Molecular profiles of mRNA levels in laser capture microdissected murine hippocampal regions differentially responsive to TMT-induced cell death

Journal of Neurochemistry

Volumn 93, Issue 1, 2005, Pages 206-220

  D'Hellencourt, Christian Lefebvre ^a,b   Harry, G Jean ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITÉ DE LA RÉUNION   (France)

Author keywords

Hippocampus; Microglia; Trimethyltin

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; TRIMETHYLTIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DENTATE GYRUS; DNA MICROARRAY; GENE EXPRESSION; GRANULE CELL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MALE; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ASTROCYTES; BRAIN INJURIES; CASPASE 3; CASPASES; CELL COUNT; CELL DEATH; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LASERS; LECTINS; MALE; MICE; MICROARRAY ANALYSIS; MICRODISSECTION; NEURONS; PHOSPHOPYRUVATE HYDRATASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRIMETHYLTIN COMPOUNDS;

MURINAE;

EID: 16244378558     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.03017.x     Document Type: Article

References (64)

1. Aarum J., Sandberg K., Haeberlein S. L. and Persson M. A. (2003) Migration and differentiation of neural precursor cells can be directed by microglia. Proc. Natl Acad. Sci. USA 100, 15 983-15 988.
2. Abe H., Watanabe M., Yaraakuni T., Kuwano R., Takahashi Y. and Kondo H. (1992) Localization of gene expression of calbindin in the brain of adult rats. Neurosci. Lett. 138, 211-215.
3. Aloisi F. (2001) Immune function of microglia. Glia 36, 165-179.
4. Ambrosini E. and Aloisi F. (2004) Chemokines and glial cells: a complex network in the central nervous system. Neurochem. Res. 29, 1017-1038.
5. Ashkenazi A. and Dixit V. M. (1999) Apoptosis control by death and decoy receptors. Curr. Opin. Cell Biol. 11, 255-260.
6. Bartholoma A. and Nave K. A. (1994) NEX-1: a novel brain-specific helix-loop-helix protein with autoregulation and sustained expression in mature cortical neurons. Mech. Dev. 48, 217-228.
7. Benveniste E. N. (1998) Cytokine actions in the central nervous system. Cytokine Growth Factor Rev. 9, 259-275.
8. Bruccoleri A., Brown H. and Harry G. J. (1998) Cellular localization and temporal elevation of tumor necrosis factor-alpha, interleukin-1 alpha, and transforming growth factor-beta 1 mRNA in hippocampal injury response induced by trimethyltin. J. Neurochem. 71. 1577-1587.
9. Chang B., Somogyi R. and Fuhrrnan S. (2001) Evidence for shared genetic programs from cluster analysis of hippocampal gene expression dynamics in development and response to injury. Restor. Neurol. Neurosci. 18, 115-125.
10. Chang L. W., Tiemeyer T. M., Wemger G. R. and McMillan D. E. (1982) Neuropathology of mouse hippocampus in acute trimethyltin intoxication. Neurobehav. Toxicol. Teratol. 4, 149-156.
11. Costa L. G. and Sulaiman R. (1986) Inhibition of protein synthesis by trimethyltin. Toxicol. Appl. Pharmacol 86, 189-196.
12. Covolan L., Ribeiro L. T., Longo B. M. and Mello L. E. (2000) Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus. Hippocampus 10, 169-180.
13. Dey P. M., Graff R. D., Lagunowich L. A. and Reuhl K. R. (1994) Selective loss of the 180-kDa neural cell adhesion molecule in hippocampus and cerebellum of the adult mouse following trimethyltin administration. Tax. Appl. Pharmacol. 126, 69-74.
14. Doctor S. V., Sultatos L. G. and Murphy S. D. (1983) Distribution of trimethyltin in various tissues of the male mouse. Toxicol. Lett. 17, 43-48.
15. Ekdahl C. T., Claasen J. H., Bonde B., Kokaia Z. and Lindvall O. (2003) Inflammation is detrimental for neurogenesis in adult brain. Proc. Natl Acad. Sci. USA 100, 13 632-13 637.
16. Elliott R. C., Khademi S., Pleasure S. J., Parent J. M. and Lowenstein D. H. (2001) Differential regulation of basic helix-loop-helix mRNAs in the dentate gyms following status epilepticus. Neuroscience 106, 79-88.
17. Elliott R. C., Miles M. F. and Lowenstein D. H. (2003) Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth. J. Neurosci. 23, 2218-2227.
18. Eskes C., Juillerat-Jeanneret L., Leuba G., Honegger P. and Monnet-Tschudi F. (2002) Involvement of microglia-neuron interactions in the tumor necrosis factor-α release, microglia activation, and neurodegeneration induced by trimethyltin. J. Neurosci. Res. 71, 583-590.
19. Estelles A., Charlton C. A. and Blau H. M. (1999) The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis. Dev. Biol. 216, 16-28.
20. Eves E. M., Xiong W., Bellacosa A., Kennedy S. G., Tsichlis P. N., Rosner M. R. and Hay N. (1998) Akt, a target of phosphatidy-linositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line. Mol. Cell Biol. 18, 2143-2152.
21. Fiedorowicz A., Figiel I., Kaminska B., Zaremba M., Wilk S. and Oderfeld-Nowak B. (2001) Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure. Brain Res. 912, 116-127.
22. Garel S., Marin F., Mattel M.-G., Vesque C., Vincent A. and Charnay P. (1997) Family of Ebf/Olf-I-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system. Dev. Dyn. 210, 191-205.
23. Geloso M. C., Vercelli A., Corvino V., Repici M., Boca M., Haglid K., Zelano G. and Michetti R. (2002) Cyclooxygenase-2 and caspase 3 expression in trimethyltin-induced apoptosis in the mouse hippocampus. Exp. Neurol. 175, 152-160.
24. Giulian D., Vaca K. and Corpuz M. (1993) Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13, 29-37.
25. Goldsworthy S. M., Stockton P. S., Trempus C. S., Foley J. F. and Maronpot R. R. (1999) Effects of fixation on RNA extraction and amplification from laser capture microdissected tissue. Mol. Carcinog. 25, 86-91.
26. Harry G. J. and Lefebvre d'Hellencourt C. (2002) The neuroinflammatory components of the trimethyltin (TMT) model of hippocampal neurodegeneration, in Neuroinflammation: Mechanisms and Management, 2nd edn. (Wood P. L., ed.), pp. 301-329. Humana Press Inc., Totowa.
27. Harry G. J. and Lefebvre d'Hellencourt C. (2003) Dentate gyrus: alterations that occur with hippocampal injury. Neurotoxicology 24, 434-356.
28. Harry G. J. and Lefebvre d'Hellencourt C. (2004) cDNA microarray analysis of laser captured microdissected hippocampal dentate and pyramidal cell layers: inflammatory factors in trimethyltin-induced injury, in Proceedings of Neurotox '03: Neurotoxicological Targets from Functional Genomics and Proteomics. (Beadle D. J., Mellor I. R. and Usherwood P. N. R., eds), pp. 105-109. Society of Chemical Industry, London.
29. Harry G. J., Tyler K. K., Lefebevre d'Hellencourt C., Tilson H. A. and Maier W. E. (2002) Morphological alterations and elevations in tumor necrosis factor-alpha, interleukin (IL)-1 alpha, and IL-6 in mixed glia cultures following exposure to trimethyltin: modulation by pro inflammatory cytokine recombinant proteins and neutralizing antibodies. Toxicol. Appl. Pharmacol. 180, 205-218.
30. Harry G. J., McPherson C., Wine R. N., Atkinson K. and Lefebvre d'Hellencourt C. (2003) Trimethyltin-induced neurogenesis in the murine hippocampus. Neurotox. Res. 5, 573-578.
31. Hastings G. A., Coleman T. A., Haudenschild C. C., Stefansson S., Smith E. P., Barthlow R., Cherry S., Sandkvist M. and Lawrence D. A. (1997) Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival. J. Biol. Chem. 272, 33 062-33 067.
32. Jiang X. H., Lam S. K., Lin M. C., Jiang S. H., Kung H. F., Slosberg E. D., Soh J. W., Weinstein I. B. and Wong B. C. (2002) Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta (1)-dependent pathway. Oncogene 21, 6113-6122.
33. Jin K., Mao X. O., Eshoo M. W., Nagayama T., Minami M., Simon R. P. and Greenberg D. A. (2001) Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann. Neurol. 50, 93-103.
34. Kamme F., Salunga R. Yu J. et al. (2003) Single-cell microarray analysis in hippocampus CA1: Demonstration and validation of cellular heterogeneity. J. Neurosci. 23, 3607-3615.
35. Kielian T. (2004) Microglia and chemokines in infectious diseases of the nervous system: views and reviews. Front. Biosci. 9, 732-750.
36. Lein E. S., Zhao X. and Gage F. H. (2004) Denning a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. J. Neurosci. 24, 3879-3889.
37. Little A. R., Benkovic S. A., Miller D. B. and O'Callaghan J. P. (2002) Chemically induced neuronal damage and gliosis: enhanced expression of the pro-inflammatory chemokine, monocyte chemoattractant protein (MCP)-1, without a corresponding increase in proinflammatory cytokines. Neuroscience 115, 307-320.
38. Liu M., Pleasure S. J., Collins A. E., Noebels J. L., Naya F. J., Tsai M. J. and Lowenstein D. H. (2000) Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc. Natl Acad. Sci. USA 97, 865-870.
39. Lukasiuk K., Kontula L. and Pitkane A. (2003) cDNA profiling of epileptogenesis in the rat brain. Eur. J. Neurosci. 17, 271-279.
40. Marin-Teva J. L., Dusart I., Colin C., Gervais A., van Rooijen N. and Mallat M. (2004) Microglia promote the death of developing Purkinje cells. Neuron 41, 535-547.
41. Matzilevich D., Rail J., Moore A., Grill R. and Dash P. (2002) High-density microarray analysis of hippocampal gene expression following experimental brain injury. J. Neurosci. Res. 67, 646-663.
42. McNamara R. K. and Lenox R. H. (2000) Differential regulation of primary protein kinase C substrate (MARCKS, MLP, GAP-43, RC3) mRNAs in the hippocampus during kainic acid-induced seizures and synaptic reorganization. J. Neurosci. Res. 62, 416-426.
43. McPherson C. A., Kubik J., Wine R. N., Lefebvre d'Hellencourt C. and Harry G. J. (2003) Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage. Neurotox. Res. 5, 339-354.
44. Meziane H., Devigne C., Tramu G. and Soumireu-Mourat B. (1997) Distribution of cholecystokinin immunoreactivity in the BALB/c mouse forebrain: an immunocytochemical study. J. Chem. Neuroanat. 12, 191-209.
45. Nakagomi S., Suzuki Y., Namikawa K., Kiryu-Seo S. and Kiyama H. (2003) Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation. J. Neurosci. 23, 5187-5196.
46. Otto V. I., Stahel P. F., Rancan M., Kariya K., Shohami E., Yatsiv I., Eugster H. P., Kossmann T., Trentz O. and Morganti-Kossmann M. C. (2001) Regulation of chemokines and chemokine receptors after experimental closed head injury. Neuroreport 12, 2059-2064.
47. Pavlakovic G., Kane M. D., Eyer C. L., Kanthasamy A. and Isom G. E. (1995) Activation of protein kinase C by trimethyltin: relevance to neurotoxicity. J. Neurochem. 65, 2338-2343.
48. Raivich G., Jones L. L., Werner A., Bluthmann H., Doetschmann T. and Kreutzberg G. W. (1999) Molecular signals for glia activation: pro- and anti-inflammatory cytokines in the injured brain. Acta Neurochir. (Wien) 73(Suppl), 21-30.
49. Reuhl K. R. and Cramner J. M. (1984) Developmental neuropathology of organotin compounds. Neurotoxicology 5, 187-204.
50. Reuhl K. R., Smallridge E. A., Chang L. W. and Mackenzie B. A. (1983) Developmental effects of trimethyltin intoxication in the neonatal mouse. I. Light microscopic studies. Neurotoxicology 4, 19-28.
51. Rezaie P., Trillo-Pazos G., Greenwood J., Everall I. P. and Male D. K. (2002) Motility and ramification of human fetal microglia in culture: an investigation using time-lapse video microscopy and image analysis. Exp. Cell Res. 274, 68-82.
52. Sharif A., Renault F., Beuvon F., Castellanos R., Canton B., Barbeito L., Junier M. P. and Chneiweiss H. (2004) The expression of PEA-15 (phosphoprotein enriched in astrocytes of 15 kDa) defines sub-populations of astrocytes and neurons throughout the adult mouse brain. Neuroscience 126, 263-275.
53. Sommer L. and Rao M. (2002) Neural stem cells and regulation of cell number. Prog. Neurobiol. 66, 1-18.
54. Stoll G., Jander S. and Schroeter M. (2002) Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system. Adv. Exp. Med. Biol. 513, 87-113.
55. Streit W. J. (2002) Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40, 133-139.
56. Takazaki R., Nishimura I. and Yashikawa K. (2002) Necdin is required for terminal differentiation and survival of primary dorsal root ganglion neurons. Exp. Cell Res. 277, 220-232.
57. Tang Y., Lu A., Aronow B. J., Wagner K. R. and Sharp F. R. (2002) Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur. J. Neurosci. 15, 1937-1952.
58. Timsit S., Rivera S., Ouagi P., Guischard F., Tremblay E., Ben-Ari Y. and Khrestchatisky M. (1999) Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death? Eur. J. Neurosci. 11, 263-278.
59. Tsai C. E., Daood M. J., Lane R. H., Hansen T. W., Gruetzmacher E. M. and Watchko J. F. (2002) P-glycoprotein expression in mouse brain increases with maturation. Biol. Neonate 8, 58-64.
60. Ubeda M., Wang X. Z., Zinszner H., Wu I., Habener J. F. and Ron D. (1996) Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol. Cell Biol. 16. 1479-1489.
61. Viviani B., Corsini E., Pesenti M., Galli C. L. and Marinovich M. (2001) Trimethyltin-activated cyclooxygenase stimulates tumor necrosis factor-alpha release from glial cells through reactive oxygen species. Toxicol. Appl. Pharmacol. 172, 93-97.
62. Vorbrodt A. W., Dodrogowaska D. H. and Tamawaski M. (2001) Immunogold study of interendothelial junction-associated and glucose transporter proteins during postnatal maturation of the mouse blood-brain barrier. J. Neurocytol. 30, 705-716.
63. Wang F., Corbett D., Osuga H., Osuga S., Ikeda J. E., Slack R. S., Hogan M. J., Hakim A. M. and Park D. S. (2002) Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat. J. Cereb. Blood Flow Metab. 22, 171-182.
64. Zhao X., Lein E. S., He A., Smith S. C., Aston C. and Gage F. H. (2001) Transcriptional profiling reveals strict boundaries between hippocampal subregions. J. Comp. Neurol. 441, 187-196.