Identification of a degradation product in stressed tablets of olmesartan medoxomil by the complementary use of HPLC hyphenated techniques

Journal of Pharmaceutical and Biomedical Analysis

Volumn 47, Issue 3, 2008, Pages 553-559

  Murakami, Tomonori ^a   Konno, Hidetoshi ^a   Fukutsu, Naoto ^a   Onodera, Michinobu ^a   Kawasaki, Takao ^a   Kusu, Fumiyo ^b  

^a DAIICHI SANKYO CO   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Degradation product; HPLC hyphenated technique; LC MS; LC NMR; Olmesartan medoxomil; Solvent elimination LC IR

Indexed keywords

CARBONYL DERIVATIVE; DIMER; DRUG; DRUG DEGRADATION PRODUCT; ESTER; OLMESARTAN;

ARTICLE; DRUG DEGRADATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED RADIATION; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; IMIDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TABLETS; TETRAZOLES;

EID: 43949099637     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.02.021     Document Type: Article

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