Hydrolysis and transesterification reactions of candesartan cilexetil observed during the solid phase extraction procedure

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 855, Issue 2 SPEC. ISS., 2007, Pages 134-138

  Ferreirós, Nerea ^a,b   Dresen, Sebastian ^a   Alonso, Rosa María ^b   Weinmann, Wolfgang ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Candesartan cilexetil; Hydrolysis; Stability; Transesterification

Indexed keywords

BLOOD PRESSURE; CHROMATOGRAPHY; ESTERIFICATION; HYDROLYSIS; METHANOL; STABILITY;

CANDESARTAN CILEXETIL; GLASS TUBES; SOLID PHASE EXTRACTION; TRANSESTERIFICATION;

REACTION KINETICS;

ANGIOTENSIN 1 RECEPTOR; CANDESARTAN; CANDESARTAN HEXETIL; DRUG METABOLITE; ESTER; METHANOL; PRODRUG;

ARTICLE; CHROMATOGRAPHY; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; ELUTION; HYDROLYSIS; PRIORITY JOURNAL; REACTION ANALYSIS; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TRANSESTERIFICATION;

EID: 34547681630     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.04.009     Document Type: Article

References (10)

1. McClellan K.L., and Goa K.L. Drugs 56 (1998) 847
2. Gilar M., Bouvier E.S.P., and Compton B.J. J. Chromatogr. A 909 (2001) 111
3. Walles M., Mullett1 W.M., and Pawliszyn J. J. Chromatogr. A 1025 (2004) 85
4. Müller C., Schäfer P., Störtzel M., Vogt S., and Weinmann W. J. Chromatogr. B 773 (2002) 47
5. Fiori M., Civitareale C., Mirante S., Magari E., and Brambilla G. Anal. Chim. Acta 529 (2005) 207
6. González L., López J.A., Alonso R.M., and Jiménez R.M. J. Chromatogr. A 949 (2002) 49
7. Stenhoff H., Lagerström P.O., and Andersen C. J. Chromatogr. B 731 (1999) 411
8. http://www.cmog.org.
9. http://www.schott.com.
10. Miyabayashi T., Okuda T., Motohashi M., Izawa K., and Yashiki T. J. Chromatogr. B 677 (1996) 123