Degradation of components in drug formulations: A comparison between HPLC and DSC methods

Journal of Pharmaceutical and Biomedical Analysis

Volumn 32, Issue 4-5, 2003, Pages 1067-1072

  Ceschel, G C ^a   Badiello, R ^a   Ronchi, C ^a   Maffei, P ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Acetyl salicylic acid; Degradation; Differential scanning calorimetry; Drug formulation; Stability testing

Indexed keywords

ACETYLSALICYLIC ACID; EXCIPIENT; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; STARCH; TALC;

ACCELERATION; ANALYTIC METHOD; CONCENTRATION RESPONSE; CONFERENCE PAPER; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DEGRADATION; DRUG FORMULATION; DRUG INCOMPATIBILITY; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICAL RESEARCH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REDUCTION; SHELF LIFE;

EID: 0042123924     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00210-3     Document Type: Conference Paper

References (9)

1. J.L. Ford, P. Timmins, in: Pharmaceutical Thermal Analysis: Technic and Applications, Chapter 10, E. Hozwood, Chichester, (1989), pp. 238-247.
2. Lindenbaum S. Swarbrick J., Boylan J.C. Calorimetry in Pharmaceutical Research and Development in Encyclopedia of Pharmaceutical Technology. 2:1990;233-250 Marcel Dekker Inc, New York.
3. Kuhnert-Brandstatter M. Pharmazie. 51:(7):1996;443-457.
4. Mura P., Faucci M.T., Manderioli A., Furlanetto S., Pinzauti S. Drug Dev. Ind. Pharm. 24:(8):1998;747-756.
5. The United States Pharmacopeia, 24th Revision, Asian Edition, United States Pharmacopeial Convention, Inc., Rockville, MD, (2000).
6. Mroso P.V., Li-Wan-Po A., Irwin W.J. J. Pharm. Sci. 71:1982;1096-1101.
7. US Pharmacopoeia, XXII Ed./N.F. XVII.
8. M.T. Faucci, S. Furlanetto, P. Mura, S. Pinzauti, Drug Analysis 2002, Bruges (Belgium), 22-25 April 2002, Book of Abstract p. 92.
9. Blondino R., Byron P. J. Pharm. Biomed. Anal. 13:(2):1995;111-119.