메뉴 건너뛰기




Volumn 28, Issue 6, 2008, Pages 375-397

Current and future antiretroviral treatment options in paediatric HIV infection

Author keywords

Antiretrovirals, therapeutic use; CCR5 receptor antagonists, therapeutic use; Children; Darunavir, therapeutic use; Efavirenz, therapeutic use; Elvitegravir, therapeutic use; Enfuvirtide, therapeutic use; Etravirine, therapeutic use

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; AMPRENAVIR; AMPRENAVIR PHOSPHATE; ANTIRETROVIRUS AGENT; ATAZANAVIR; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; DARUNAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EMTRICITABINE; ENFUVIRTIDE; ETRAVIRINE; INDINAVIR; INTEGRASE INHIBITOR; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; NUCLEOSIDE ANALOG; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; TENOFOVIR; TIPRANAVIR; UNINDEXED DRUG; VIRUS RNA; ZIDOVUDINE;

EID: 43849110759     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-200828060-00005     Document Type: Review
Times cited : (35)

References (117)
  • 1
    • 43849112179 scopus 로고    scopus 로고
    • World Health Organization (WHO). Antiretroviral treatment of HIV infection in infants and children in resource-limited settings, towards universal access: recommendations for a public health approach (2006 revision) [online]. Available from URL: http://www.who.int/hiv/pub/guidelines/art/en/ index.html [Accessed 2007 Jul 1]
    • World Health Organization (WHO). Antiretroviral treatment of HIV infection in infants and children in resource-limited settings, towards universal access: recommendations for a public health approach (2006 revision) [online]. Available from URL: http://www.who.int/hiv/pub/guidelines/art/en/ index.html [Accessed 2007 Jul 1]
  • 2
    • 0034641328 scopus 로고    scopus 로고
    • Reduction in mortality with availability of antiretroviral therapy for children with perinatal HIV-1 infection. Italian Register for HIV Infection in Children and the Italian National AIDS Registry
    • de Martino M, Tovo PA, Balducci M, et al. Reduction in mortality with availability of antiretroviral therapy for children with perinatal HIV-1 infection. Italian Register for HIV Infection in Children and the Italian National AIDS Registry. JAMA 2000; 284 (2): 190-7
    • (2000) JAMA , vol.284 , Issue.2 , pp. 190-197
    • de Martino, M.1    Tovo, P.A.2    Balducci, M.3
  • 3
    • 0242288797 scopus 로고    scopus 로고
    • Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland
    • Gibb DM, Duong T, Tookey PA, et al. Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland. BMJ 2003; 327 (7422): 1019
    • (2003) BMJ , vol.327 , Issue.7422 , pp. 1019
    • Gibb, D.M.1    Duong, T.2    Tookey, P.A.3
  • 4
    • 33746548652 scopus 로고    scopus 로고
    • March, online, Available from URL:, Accessed 2007 Jul 1
    • World Health Organization (WHO). Progress on global access to HIV antiretroviral therapy: a report on "3 by 5" and beyond (March 2006) [online]. Available from URL: http://www.wpro.who.int/health_topics/ antiretroviral_therapy/publications.htm [Accessed 2007 Jul 1]
    • (2006) Progress on global access to HIV antiretroviral therapy: A report on 3 by 5
  • 5
    • 33646773540 scopus 로고    scopus 로고
    • Outcomes for human immunodeficiency virus-1-infected infants in the United kingdom and Republic of Ireland in the era of effective antiretroviral therapy
    • Doerholt K, Duong T, Tookey P, et al. Outcomes for human immunodeficiency virus-1-infected infants in the United kingdom and Republic of Ireland in the era of effective antiretroviral therapy. Pediatr Infect Dis J 2006; 25 (5): 420-6
    • (2006) Pediatr Infect Dis J , vol.25 , Issue.5 , pp. 420-426
    • Doerholt, K.1    Duong, T.2    Tookey, P.3
  • 6
    • 0035999346 scopus 로고    scopus 로고
    • Lipodystrophy syndrome in human immunodeficiency virus-infected children
    • Amaya RA, Kozinetz CA, McMeans A, et al. Lipodystrophy syndrome in human immunodeficiency virus-infected children. Pediatr Infect Dis J 2002; 21 (5): 405-10
    • (2002) Pediatr Infect Dis J , vol.21 , Issue.5 , pp. 405-410
    • Amaya, R.A.1    Kozinetz, C.A.2    McMeans, A.3
  • 7
    • 0037231547 scopus 로고    scopus 로고
    • Metabolic complications of antiretroviral therapy in children
    • Leonard EG, McComsey GA. Metabolic complications of antiretroviral therapy in children. Pediatr Infect Dis J 2003; 22 (1): 77-84
    • (2003) Pediatr Infect Dis J , vol.22 , Issue.1 , pp. 77-84
    • Leonard, E.G.1    McComsey, G.A.2
  • 8
    • 0037072066 scopus 로고    scopus 로고
    • Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: A collabo- rative analysis of prospective studies
    • Egger M, May M, Chene G, et al. Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collabo- rative analysis of prospective studies. Lancet 2002; 360 (9327): 119-29
    • (2002) Lancet , vol.360 , Issue.9327 , pp. 119-129
    • Egger, M.1    May, M.2    Chene, G.3
  • 9
    • 0041631056 scopus 로고    scopus 로고
    • Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study
    • Florence E, Lundgren J, Dreezen C, et al. Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study. HIV Med 2003; 4 (3): 255-62
    • (2003) HIV Med , vol.4 , Issue.3 , pp. 255-262
    • Florence, E.1    Lundgren, J.2    Dreezen, C.3
  • 10
    • 0038662719 scopus 로고    scopus 로고
    • Survival benefit of initiating antiretroviral therapy in HIV-infected persons in different CD4+ cell strata
    • Palella Jr FJ, Deloria-Knoll M, Chmiel JS, et al. Survival benefit of initiating antiretroviral therapy in HIV-infected persons in different CD4+ cell strata. Ann Intern Med 2003; 138 (8): 620-6
    • (2003) Ann Intern Med , vol.138 , Issue.8 , pp. 620-626
    • Palella Jr, F.J.1    Deloria-Knoll, M.2    Chmiel, J.S.3
  • 11
    • 43849103185 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. 1994 revised classi- fication system for human immunodeficiency infection in children less than 13 years of age. MMWR Recomm Rep 1994 Sep 30; 43 (RR-12): 1-19
    • Centers for Disease Control and Prevention. 1994 revised classi- fication system for human immunodeficiency infection in children less than 13 years of age. MMWR Recomm Rep 1994 Sep 30; 43 (RR-12): 1-19
  • 12
    • 0032873156 scopus 로고    scopus 로고
    • Paediatric HIV-1 infection
    • Burns DN, Mofenson LM. Paediatric HIV-1 infection. Lancet 1999; 354 Suppl. 2: SII1-6
    • (1999) Lancet , vol.354 , Issue.SUPPL. 2
    • Burns, D.N.1    Mofenson, L.M.2
  • 13
    • 33846794933 scopus 로고    scopus 로고
    • Temporal trends in postseroconversion CD4 cell count and HIV load: The Concerted Action on Seroconversion to AIDS and Death in Europe Collaboration, 1985-2002
    • Dorrucci M, Rezza G, Porter K, et al. Temporal trends in postseroconversion CD4 cell count and HIV load: the Concerted Action on Seroconversion to AIDS and Death in Europe Collaboration, 1985-2002. J Infect Dis 2007; 195 (4): 525-34
    • (2007) J Infect Dis , vol.195 , Issue.4 , pp. 525-534
    • Dorrucci, M.1    Rezza, G.2    Porter, K.3
  • 14
    • 28044466931 scopus 로고    scopus 로고
    • HIV Paediatric Prognostic Markers Collaborative Study. Use of total lymphocyte count for informing when to start antiretroviral therapy in HIV-infected children: a meta-analysis of longi-tudinal data. Lancet 2005; 366 (9500): 1868-74
    • HIV Paediatric Prognostic Markers Collaborative Study. Use of total lymphocyte count for informing when to start antiretroviral therapy in HIV-infected children: a meta-analysis of longi-tudinal data. Lancet 2005; 366 (9500): 1868-74
  • 15
    • 33745839882 scopus 로고    scopus 로고
    • HIV Paediatric Prognostic Markers Collaborative Study. Predictive value of absolute CD4 cell count for disease progression in untreated HIV-1-infected children. AIDS 2006; 20 (9): 1289-94
    • HIV Paediatric Prognostic Markers Collaborative Study. Predictive value of absolute CD4 cell count for disease progression in untreated HIV-1-infected children. AIDS 2006; 20 (9): 1289-94
  • 16
    • 0345714615 scopus 로고    scopus 로고
    • Short-term risk of disease progression in HIV-1-infected children receiving no antiretroviral therapy or zidovudine monotherapy: A meta-analysis
    • Dunn D. Short-term risk of disease progression in HIV-1-infected children receiving no antiretroviral therapy or zidovudine monotherapy: a meta-analysis. Lancet 2003; 362 (9396): 1605-11
    • (2003) Lancet , vol.362 , Issue.9396 , pp. 1605-1611
    • Dunn, D.1
  • 17
    • 4043162723 scopus 로고    scopus 로고
    • PENTA guidelines for the use of antiretroviral therapy, 2004
    • Sharland M, Blanche S, Castelli G, et al. PENTA guidelines for the use of antiretroviral therapy, 2004. HIV Med 2004; 5 Suppl. 2: 61-86
    • (2004) HIV Med , vol.5 , Issue.SUPPL. 2 , pp. 61-86
    • Sharland, M.1    Blanche, S.2    Castelli, G.3
  • 18
    • 43849102689 scopus 로고    scopus 로고
    • François-Xavier Bagnoud Center, UMDNJ, The Health Resources and Services Administration, et al. Working group on antiretroviral therapy and medical management of HIV-infected children: guidelines for the use of antiretroviral agents in pediatric HIV infection [online]. Available at URL: http://aidsinfo.nih.gov/contentfiles/PediatricGuidelines.pdf [Accessed 2008 Apr 30]
    • François-Xavier Bagnoud Center, UMDNJ, The Health Resources and Services Administration, et al. Working group on antiretroviral therapy and medical management of HIV-infected children: guidelines for the use of antiretroviral agents in pediatric HIV infection [online]. Available at URL: http://aidsinfo.nih.gov/contentfiles/PediatricGuidelines.pdf [Accessed 2008 Apr 30]
  • 19
    • 0033047797 scopus 로고    scopus 로고
    • Italian guidelines for antiretroviral therapy in children with human immunodeficiency virus-type 1 infection. Italian Register for HIV Infection in Children
    • Italian guidelines for antiretroviral therapy in children with human immunodeficiency virus-type 1 infection. Italian Register for HIV Infection in Children. Acta Paediatr 1999; 88 (2): 228-32
    • (1999) Acta Paediatr , vol.88 , Issue.2 , pp. 228-232
  • 20
    • 0035660904 scopus 로고    scopus 로고
    • Recommendations for antiretroviral therapy in HIV-infected children: Completely revised and updated consensus statement of the Pediatric AIDS Committee (PAAD) and the German Society for Pediatric Infectiology
    • Niehues T, Wintergerst U, Funk M, et al. Recommendations for antiretroviral therapy in HIV-infected children: completely revised and updated consensus statement of the Pediatric AIDS Committee (PAAD) and the German Society for Pediatric Infectiology. Monatsschr Kinderheilk 2001; 149: 1372-82
    • (2001) Monatsschr Kinderheilk , vol.149 , pp. 1372-1382
    • Niehues, T.1    Wintergerst, U.2    Funk, M.3
  • 21
    • 0035908754 scopus 로고    scopus 로고
    • Commissie Richtlijnen van de Nederlandse Vereniging van Aids Behandelaren. CBO guidelines Antiretroviral therapy in the Netherlands
    • in Dutch
    • Borleffs JC, Danner SA, Lange JM, et al. Commissie Richtlijnen van de Nederlandse Vereniging van Aids Behandelaren. CBO guidelines Antiretroviral therapy in the Netherlands [in Dutch]. Ned Tijdschr Geneeskd 2001; 145 (33): 1585-9
    • (2001) Ned Tijdschr Geneeskd , vol.145 , Issue.33 , pp. 1585-1589
    • Borleffs, J.C.1    Danner, S.A.2    Lange, J.M.3
  • 22
    • 34547173254 scopus 로고    scopus 로고
    • Nucleoside and nucleotide reverse transcriptase inhibitors in children
    • Giaquinto C, Rampon O, Penazzato M, et al. Nucleoside and nucleotide reverse transcriptase inhibitors in children. Clin Drug Investig 2007; 27 (8): 509-31
    • (2007) Clin Drug Investig , vol.27 , Issue.8 , pp. 509-531
    • Giaquinto, C.1    Rampon, O.2    Penazzato, M.3
  • 23
    • 3142582062 scopus 로고    scopus 로고
    • Triple nucleoside reverse transcriptase inhibitor therapy in children
    • Handforth J, Sharland M. Triple nucleoside reverse transcriptase inhibitor therapy in children. Paediatr Drugs 2004; 6 (3): 147-59
    • (2004) Paediatr Drugs , vol.6 , Issue.3 , pp. 147-159
    • Handforth, J.1    Sharland, M.2
  • 24
    • 33748499796 scopus 로고    scopus 로고
    • Switching from protease inhibitor-based-HAART to a protease inhibitor-sparing regimen is associated with improved specific HIV-immune responses in HIV-infected children
    • Pensieroso S, Romiti ML, Palma P, et al. Switching from protease inhibitor-based-HAART to a protease inhibitor-sparing regimen is associated with improved specific HIV-immune responses in HIV-infected children. AIDS 2006; 20 (14): 1893-6
    • (2006) AIDS , vol.20 , Issue.14 , pp. 1893-1896
    • Pensieroso, S.1    Romiti, M.L.2    Palma, P.3
  • 25
    • 33750253867 scopus 로고    scopus 로고
    • An updated systematic overview of triple combination therapy in antiretroviral-naive HIV-infected adults
    • Bartlett JA, Fath MJ, Demasi R, et al. An updated systematic overview of triple combination therapy in antiretroviral-naive HIV-infected adults. AIDS 2006; 20 (16): 2051-64
    • (2006) AIDS , vol.20 , Issue.16 , pp. 2051-2064
    • Bartlett, J.A.1    Fath, M.J.2    Demasi, R.3
  • 26
    • 30944468562 scopus 로고    scopus 로고
    • Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV
    • Gallant JE, DeJesus E, Arribas JR, et al. Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. N Engl J Med 2006; 354 (3): 251-60
    • (2006) N Engl J Med , vol.354 , Issue.3 , pp. 251-260
    • Gallant, J.E.1    DeJesus, E.2    Arribas, J.R.3
  • 27
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
    • Gallant JE, Staszewski S, Pozniak AL, et al. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA 2004; 292 (2): 191-201
    • (2004) JAMA , vol.292 , Issue.2 , pp. 191-201
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3
  • 28
    • 0033576814 scopus 로고    scopus 로고
    • Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team
    • Starr SE, Fletcher CV, Spector SA, et al. Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team. N Engl J Med 1999; 341 (25): 1874-81
    • (1999) N Engl J Med , vol.341 , Issue.25 , pp. 1874-1881
    • Starr, S.E.1    Fletcher, C.V.2    Spector, S.A.3
  • 29
    • 33750267263 scopus 로고    scopus 로고
    • Long-term results of initial therapy with abacavir and lamivudine combined with efavirenz, amprenavir/ritonavir, or stavudine
    • Bartlett JA, Johnson J, Herrera G, et al. Long-term results of initial therapy with abacavir and lamivudine combined with efavirenz, amprenavir/ritonavir, or stavudine. J Acquir Immune Defic Syndr 2006; 43 (3): 284-92
    • (2006) J Acquir Immune Defic Syndr , vol.43 , Issue.3 , pp. 284-292
    • Bartlett, J.A.1    Johnson, J.2    Herrera, G.3
  • 30
    • 20844462378 scopus 로고    scopus 로고
    • Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults
    • DeJesus E, Herrera G, Teofilo E, et al. Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults. Clin Infect Dis 2004; 39 (7): 1038-46
    • (2004) Clin Infect Dis , vol.39 , Issue.7 , pp. 1038-1046
    • DeJesus, E.1    Herrera, G.2    Teofilo, E.3
  • 31
    • 33749360470 scopus 로고    scopus 로고
    • ACTG 5095: Zidovudine/ lamivudine/abacavir vs zidovudine/lamivudine + efavirenz vs zidovudine/ lamivudine/abacavir + efavirenz for initial HIV therapy
    • Washington, DC
    • Gulick RM, Ribaudo HJ, Shikuma CM, et al. ACTG 5095: zidovudine/ lamivudine/abacavir vs zidovudine/lamivudine + efavirenz vs zidovudine/ lamivudine/abacavir + efavirenz for initial HIV therapy. In: Antimicrobial Agents and Chemotherapy: 45th Interscience Conference, 2005, Washington, DC
    • (2005) Antimicrobial Agents and Chemotherapy: 45th Interscience Conference
    • Gulick, R.M.1    Ribaudo, H.J.2    Shikuma, C.M.3
  • 32
    • 2342537759 scopus 로고    scopus 로고
    • Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection
    • Gulick RM, Ribaudo HJ, Shikuma CM, et al. Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection. N Engl J Med 2004; 350 (18): 1850-61
    • (2004) N Engl J Med , vol.350 , Issue.18 , pp. 1850-1861
    • Gulick, R.M.1    Ribaudo, H.J.2    Shikuma, C.M.3
  • 33
    • 15044341385 scopus 로고    scopus 로고
    • Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: Results of the Ziagen Once Daily in Antiretroviral Combination Study
    • Moyle GJ, DeJesus E, Cahn P, et al. Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: results of the Ziagen Once Daily in Antiretroviral Combination Study. J Acquir Immune Defic Syndr 2005; 38 (4): 417-25
    • (2005) J Acquir Immune Defic Syndr , vol.38 , Issue.4 , pp. 417-425
    • Moyle, G.J.1    DeJesus, E.2    Cahn, P.3
  • 34
    • 0345012053 scopus 로고    scopus 로고
    • Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection
    • Robbins GK, De Gruttola V, Shafer RW, et al. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003; 349 (24): 2293-303
    • (2003) N Engl J Med , vol.349 , Issue.24 , pp. 2293-2303
    • Robbins, G.K.1    De Gruttola, V.2    Shafer, R.W.3
  • 35
    • 0344149561 scopus 로고    scopus 로고
    • Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection
    • Shafer RW, Smeaton LM, Robbins GK, et al. Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003; 349 (24): 2304-15
    • (2003) N Engl J Med , vol.349 , Issue.24 , pp. 2304-2315
    • Shafer, R.W.1    Smeaton, L.M.2    Robbins, G.K.3
  • 36
    • 0033576816 scopus 로고    scopus 로고
    • Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults: Study 006 team
    • Staszewski S, Morales-Ramirez J, Tashima KT, et al. Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults: study 006 team. N Engl J Med 1999; 341 (25): 1865-73
    • (1999) N Engl J Med , vol.341 , Issue.25 , pp. 1865-1873
    • Staszewski, S.1    Morales-Ramirez, J.2    Tashima, K.T.3
  • 37
    • 38949202140 scopus 로고    scopus 로고
    • Durable viral suppression on EFV-based HAART: 168 weeks of follow-up
    • abstract no. TUPEB4547, Presented at the, Jul 11-16; Bangkok
    • Tashima K, Staszewski S, Nelson M, et al. Durable viral suppression on EFV-based HAART: 168 weeks of follow-up [abstract no. TUPEB4547]. Presented at the 15th International AIDS Conference; 2004 Jul 11-16; Bangkok
    • (2004) 15th International AIDS Conference
    • Tashima, K.1    Staszewski, S.2    Nelson, M.3
  • 38
    • 11144357656 scopus 로고    scopus 로고
    • Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: A randomised open-label trial, the 2NN Study
    • van Leth F, Phanuphak P, Ruxrungtham K, et al. Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet 2004; 363 (9417): 1253-63
    • (2004) Lancet , vol.363 , Issue.9417 , pp. 1253-1263
    • van Leth, F.1    Phanuphak, P.2    Ruxrungtham, K.3
  • 39
    • 1942471103 scopus 로고    scopus 로고
    • Antiretroviral therapy for previously untreated HIV-1-infected adults: 2NN, or just one?
    • Carr A. Antiretroviral therapy for previously untreated HIV-1-infected adults: 2NN, or just one? Lancet 2004; 363 (9417): 1248-50
    • (2004) Lancet , vol.363 , Issue.9417 , pp. 1248-1250
    • Carr, A.1
  • 40
    • 1842563002 scopus 로고    scopus 로고
    • Efavirenz versus nevirapine in current clinical practice: A prospective, open-label observational study
    • Manfredi R, Calza L, Chiodo F. Efavirenz versus nevirapine in current clinical practice: a prospective, open-label observational study. J Acquir Immune Defic Syndr 2004; 35 (5): 492-502
    • (2004) J Acquir Immune Defic Syndr , vol.35 , Issue.5 , pp. 492-502
    • Manfredi, R.1    Calza, L.2    Chiodo, F.3
  • 41
    • 1642565249 scopus 로고    scopus 로고
    • Nevirapine- versus efavirenz-based highly active antiretroviral therapy regimens in antiretroviral-naive patients with advanced HIV infection
    • Manosuthi W, Sungkanuparph S, Vibhagool A, et al. Nevirapine- versus efavirenz-based highly active antiretroviral therapy regimens in antiretroviral-naive patients with advanced HIV infection. HIV Med 2004; 5 (2): 105-9
    • (2004) HIV Med , vol.5 , Issue.2 , pp. 105-109
    • Manosuthi, W.1    Sungkanuparph, S.2    Vibhagool, A.3
  • 42
    • 0035951441 scopus 로고    scopus 로고
    • Tolerance of efavirenz in children
    • Teglas JP, Quartier P, Treluyer JM, et al. Tolerance of efavirenz in children. AIDS 2001; 15 (2): 241-3
    • (2001) AIDS , vol.15 , Issue.2 , pp. 241-243
    • Teglas, J.P.1    Quartier, P.2    Treluyer, J.M.3
  • 43
    • 0036532103 scopus 로고    scopus 로고
    • Nucleoside-analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with human immunodeficiency virus type 1
    • Krogstad P, Lee S, Johnson G, et al. Nucleoside-analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with human immunodeficiency virus type 1. Clin Infect Dis 2002; 34 (7): 991-1001
    • (2002) Clin Infect Dis , vol.34 , Issue.7 , pp. 991-1001
    • Krogstad, P.1    Lee, S.2    Johnson, G.3
  • 44
    • 0030990223 scopus 로고    scopus 로고
    • Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection
    • Luzuriaga K, Bryson Y, Krogstad P, et al. Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection. N Engl J Med 1997; 336 (19): 1343-9
    • (1997) N Engl J Med , vol.336 , Issue.19 , pp. 1343-1349
    • Luzuriaga, K.1    Bryson, Y.2    Krogstad, P.3
  • 45
    • 0029845343 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and activity of nevirapine in human immunodeficiency virus type 1-infected children
    • Luzuriaga K, Bryson Y, McSherry G, et al. Pharmacokinetics, safety, and activity of nevirapine in human immunodeficiency virus type 1-infected children. J Infect Dis 1996; 174 (4): 713-21
    • (1996) J Infect Dis , vol.174 , Issue.4 , pp. 713-721
    • Luzuriaga, K.1    Bryson, Y.2    McSherry, G.3
  • 46
    • 2942625676 scopus 로고    scopus 로고
    • A trial of three antiretroviral regimens in HIV-1-infected children
    • Luzuriaga K, McManus M, Mofenson L, et al. A trial of three antiretroviral regimens in HIV-1-infected children. N Engl J Med 2004; 350 (24): 2471-80
    • (2004) N Engl J Med , vol.350 , Issue.24 , pp. 2471-2480
    • Luzuriaga, K.1    McManus, M.2    Mofenson, L.3
  • 47
    • 0033760913 scopus 로고    scopus 로고
    • Nevirapine: Pharmacokinetic considerations in children and pregnant women
    • Mirochnick M, Clarke DF, Dorenbaum A. Nevirapine: pharmacokinetic considerations in children and pregnant women. Clin Pharmacokinet 2000; 39 (4): 281-93
    • (2000) Clin Pharmacokinet , vol.39 , Issue.4 , pp. 281-293
    • Mirochnick, M.1    Clarke, D.F.2    Dorenbaum, A.3
  • 48
    • 0043130149 scopus 로고    scopus 로고
    • Nevirapine use in HIV-1-infected children
    • Verweel G, Sharland M, Lyall H, et al. Nevirapine use in HIV-1-infected children. AIDS 2003; 17 (11): 1639-47
    • (2003) AIDS , vol.17 , Issue.11 , pp. 1639-1647
    • Verweel, G.1    Sharland, M.2    Lyall, H.3
  • 49
    • 0034632922 scopus 로고    scopus 로고
    • Combination nucleoside analog reverse transcriptase inhibitor(s) plus nevirapine, nelfinavir, or ritonavir in stable antiretroviral therapy-experienced HIV-infected children: Week 24 results of a randomized controlled trial: PACTG 377. Pediatric AIDS Clinical Trials Group 377 Study Team
    • Wiznia A, Stanley K, Krogstad P, et al. Combination nucleoside analog reverse transcriptase inhibitor(s) plus nevirapine, nelfinavir, or ritonavir in stable antiretroviral therapy-experienced HIV-infected children: week 24 results of a randomized controlled trial: PACTG 377. Pediatric AIDS Clinical Trials Group 377 Study Team. AIDS Res Hum Retroviruses 2000; 16 (12): 1113-21
    • (2000) AIDS Res Hum Retroviruses , vol.16 , Issue.12 , pp. 1113-1121
    • Wiznia, A.1    Stanley, K.2    Krogstad, P.3
  • 50
    • 26944466328 scopus 로고    scopus 로고
    • Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: Pediatric AIDS clinical trials group protocol 403
    • King JR, Nachman S, Yogev R, et al. Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403. Pediatr Infect Dis J 2005; 24 (10): 880-5
    • (2005) Pediatr Infect Dis J , vol.24 , Issue.10 , pp. 880-885
    • King, J.R.1    Nachman, S.2    Yogev, R.3
  • 51
    • 33847746248 scopus 로고    scopus 로고
    • Efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) in Thai HIV-infected patients
    • Kiertiburanakul S, Khongnorasat S, Rattanasiri S, et al. Efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) in Thai HIV-infected patients. J Med Assoc Thai 2007; 90 (2): 237-43
    • (2007) J Med Assoc Thai , vol.90 , Issue.2 , pp. 237-243
    • Kiertiburanakul, S.1    Khongnorasat, S.2    Rattanasiri, S.3
  • 52
    • 33845890515 scopus 로고    scopus 로고
    • Pharmacokinetics of two generic fixed-dose combinations for HIV-infected children (Pedimune Baby & Pedimune Junior) are similar to the branded products in healthy adults
    • L'Homme RF, Dijkema T, Warris A, et al. Pharmacokinetics of two generic fixed-dose combinations for HIV-infected children (Pedimune Baby & Pedimune Junior) are similar to the branded products in healthy adults. J Antimicrob Chemother 2007; 59 (1): 92-6
    • (2007) J Antimicrob Chemother , vol.59 , Issue.1 , pp. 92-96
    • L'Homme, R.F.1    Dijkema, T.2    Warris, A.3
  • 53
    • 10644291830 scopus 로고    scopus 로고
    • Effectiveness of generic fixed-dose combinations of highly active antiretroviral therapy for treatment of HIV infection in India
    • Pujari SN, Patel AK, Naik E, et al. Effectiveness of generic fixed-dose combinations of highly active antiretroviral therapy for treatment of HIV infection in India. J Acquir Immune Defic Syndr 2004; 37 (5): 1566-9
    • (2004) J Acquir Immune Defic Syndr , vol.37 , Issue.5 , pp. 1566-1569
    • Pujari, S.N.1    Patel, A.K.2    Naik, E.3
  • 54
    • 33645290009 scopus 로고    scopus 로고
    • A randomized crossover study to determine bioequivalence of generic and brand name nevirapine, zidovudine, and lamivudine in HIV-negative women in India
    • Vezina HE, Henry K, Ravindran GD, et al. A randomized crossover study to determine bioequivalence of generic and brand name nevirapine, zidovudine, and lamivudine in HIV-negative women in India. J Acquir Immune Defic Syndr 2006; 41 (2): 131-6
    • (2006) J Acquir Immune Defic Syndr , vol.41 , Issue.2 , pp. 131-136
    • Vezina, H.E.1    Henry, K.2    Ravindran, G.D.3
  • 55
    • 34347357578 scopus 로고    scopus 로고
    • Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children
    • Wamalwa DC, Farquhar C, Obimbo EM, et al. Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children. J Acquir Immune Defic Syndr 2007; 45 (3): 311-7
    • (2007) J Acquir Immune Defic Syndr , vol.45 , Issue.3 , pp. 311-317
    • Wamalwa, D.C.1    Farquhar, C.2    Obimbo, E.M.3
  • 56
    • 13444279867 scopus 로고    scopus 로고
    • Prevalence of antiretroviral drug resistance mutations in chronically HIV-infected, treatment-naive patients: Implications for routine resistance screening before initiation of antiretroviral therapy
    • Novak RM, Chen L, MacArthur RD, et al. Prevalence of antiretroviral drug resistance mutations in chronically HIV-infected, treatment-naive patients: implications for routine resistance screening before initiation of antiretroviral therapy. Clin Infect Dis 2005; 40 (3): 468-74
    • (2005) Clin Infect Dis , vol.40 , Issue.3 , pp. 468-474
    • Novak, R.M.1    Chen, L.2    MacArthur, R.D.3
  • 57
    • 2942529150 scopus 로고    scopus 로고
    • The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infected persons in 10 US cities
    • Weinstock HS, Zaidi I, Heneine W, et al. The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infected persons in 10 US cities. J Infect Dis 2004; 189 (12): 2174-80
    • (2004) J Infect Dis , vol.189 , Issue.12 , pp. 2174-2180
    • Weinstock, H.S.1    Zaidi, I.2    Heneine, W.3
  • 58
    • 24644472997 scopus 로고    scopus 로고
    • Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: Implications for clinical management
    • Wensing AM, van de Vijver DA, Angarano G, et al. Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management. J Infect Dis 2005; 192 (6): 958-66
    • (2005) J Infect Dis , vol.192 , Issue.6 , pp. 958-966
    • Wensing, A.M.1    van de Vijver, D.A.2    Angarano, G.3
  • 59
    • 0037945435 scopus 로고    scopus 로고
    • Toxicity of non-nucleoside analogue reverse transcriptase inhibitors
    • Kontorinis N, Dieterich DT. Toxicity of non-nucleoside analogue reverse transcriptase inhibitors. Semin Liver Dis 2003; 23 (2): 173-82
    • (2003) Semin Liver Dis , vol.23 , Issue.2 , pp. 173-182
    • Kontorinis, N.1    Dieterich, D.T.2
  • 60
    • 20044382589 scopus 로고    scopus 로고
    • Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects
    • Sanne I, Mommeja-Marin H, Hinkle J, et al. Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects. J Infect Dis 2005; 191 (6): 825-9
    • (2005) J Infect Dis , vol.191 , Issue.6 , pp. 825-829
    • Sanne, I.1    Mommeja-Marin, H.2    Hinkle, J.3
  • 61
    • 43849099067 scopus 로고    scopus 로고
    • Clarification of risk factors for severe, life threatening and fatal hepatotoxicity with Viramune (nevirapine) [letter]
    • Shepard K. Clarification of risk factors for severe, life threatening and fatal hepatotoxicity with Viramune (nevirapine) [letter]. Rigdefield (CT): Boehringer Ingelheim Pharmaceuticals, 2004
    • (2004) Rigdefield (CT): Boehringer Ingelheim Pharmaceuticals
    • Shepard, K.1
  • 62
    • 34249054728 scopus 로고    scopus 로고
    • Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naive and - experienced HIV-infected patients with high and low CD4+ T-cell counts
    • Mocroft A, Staszewski S, Weber R, et al. Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naive and - experienced HIV-infected patients with high and low CD4+ T-cell counts. Antivir Ther 2007; 12 (3): 325-33
    • (2007) Antivir Ther , vol.12 , Issue.3 , pp. 325-333
    • Mocroft, A.1    Staszewski, S.2    Weber, R.3
  • 63
    • 0035913939 scopus 로고    scopus 로고
    • Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012)
    • Eshleman SH, Mracna M, Guay LA, et al. Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012). AIDS 2001; 15 (15): 1951-7
    • (2001) AIDS , vol.15 , Issue.15 , pp. 1951-1957
    • Eshleman, S.H.1    Mracna, M.2    Guay, L.A.3
  • 64
    • 0035946701 scopus 로고    scopus 로고
    • Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1
    • Mandelbrot L, Landreau-Mascaro A, Rekacewicz C, et al. Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1. JAMA 2001; 285 (16): 2083-93
    • (2001) JAMA , vol.285 , Issue.16 , pp. 2083-2093
    • Mandelbrot, L.1    Landreau-Mascaro, A.2    Rekacewicz, C.3
  • 65
    • 43849083888 scopus 로고    scopus 로고
    • Kaletra® (lopinavir-ritonavir tablets, oral solution). Prescribing information. North Chicago (IL): Abbott Laboratories, 2007
    • Kaletra® (lopinavir-ritonavir tablets, oral solution). Prescribing information. North Chicago (IL): Abbott Laboratories, 2007
  • 66
    • 42049094266 scopus 로고    scopus 로고
    • Pharmacokinetics and 24-week efficacy and safety of lopinavir/ritonavir in HIV-1 infected infants < 6 weeks of age
    • Feb 25-28; Los Angeles CA
    • Pinto J, Robbins B, Chen J, et al. Pharmacokinetics and 24-week efficacy and safety of lopinavir/ritonavir in HIV-1 infected infants < 6 weeks of age. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Pinto, J.1    Robbins, B.2    Chen, J.3
  • 67
    • 43849106465 scopus 로고    scopus 로고
    • Seven-year followup of a lopinavir/ritonavir (LPV/r)-based regimen in antiretroviral (ARV)-naive subjects [poster PE7.9/3]. European AIDS
    • Nov 17-20: Dublin
    • Murphy RL, da Silva B, McMillan F, et al. Seven-year followup of a lopinavir/ritonavir (LPV/r)-based regimen in antiretroviral (ARV)-naive subjects [poster PE7.9/3]. European AIDS, 10th Conference; 2005 Nov 17-20: Dublin
    • (2005) 10th Conference
    • Murphy, R.L.1    da Silva, B.2    McMillan, F.3
  • 68
    • 0037182766 scopus 로고    scopus 로고
    • Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection
    • Walmsley S, Bernstein B, King M, et al. Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection. N Engl J Med 2002; 346 (26): 2039-46
    • (2002) N Engl J Med , vol.346 , Issue.26 , pp. 2039-2046
    • Walmsley, S.1    Bernstein, B.2    King, M.3
  • 69
    • 3843151487 scopus 로고    scopus 로고
    • SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir/ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients
    • Gathe Jr JC, Ive P, Wood R, et al. SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir/ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients. AIDS 2004; 18 (11): 1529-37
    • (2004) AIDS , vol.18 , Issue.11 , pp. 1529-1537
    • Gathe Jr, J.C.1    Ive, P.2    Wood, R.3
  • 70
    • 0347990584 scopus 로고    scopus 로고
    • The NEAT study: A 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients
    • Rodriguez-French A, Boghossian J, Gray GE, et al. The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients. J Acquir Immune Defic Syndr 2004; 35 (1): 22-32
    • (2004) J Acquir Immune Defic Syndr , vol.35 , Issue.1 , pp. 22-32
    • Rodriguez-French, A.1    Boghossian, J.2    Gray, G.E.3
  • 71
    • 43849092481 scopus 로고    scopus 로고
    • Safety and antiviral activity of fosamprenavir/ritonavir once daily regimens in HIV-infected pediatric subjects ages 2 to 18 years (48-week interim data, study APV20003)
    • abstract no. 719, Feb 25-28; Los Angeles CA
    • Chadwick E, Borkowsky W, Fortuny C, et al. Safety and antiviral activity of fosamprenavir/ritonavir once daily regimens in HIV-infected pediatric subjects ages 2 to 18 years (48-week interim data, study APV20003) [abstract no. 719]. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA))
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Chadwick, E.1    Borkowsky, W.2    Fortuny, C.3
  • 72
    • 43849087187 scopus 로고    scopus 로고
    • Safety and antiviral activity of fosamprenavir-containing regimens in HIV-infected 2- to 18-year-old pediatric subjects (interim data, study APV29005)
    • abstract no. 718, Feb 25-28; Los Angeles CA
    • Cunningham C, Freedman A, Read S, et al. Safety and antiviral activity of fosamprenavir-containing regimens in HIV-infected 2- to 18-year-old pediatric subjects (interim data, study APV29005) [abstract no. 718]. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Cunningham, C.1    Freedman, A.2    Read, S.3
  • 73
    • 43849084067 scopus 로고    scopus 로고
    • PREA Labeling Changes, online, Available from URL:, Accessed 2008 Apr 30
    • PREA Labeling Changes. Lexiva oral suspension (fosamprenavir) [online]. Available from URL: http://www.fda.gov/ cder/foi/label/2007/022116lbl.pdf [Accessed 2008 Apr 30]
    • Lexiva oral suspension (fosamprenavir)
  • 74
    • 33749867216 scopus 로고    scopus 로고
    • The KLEAN study: Fosamprenavir + ritonavir (FPV/r) versus lopinavir/ritonavir (LPV/r) in antiretroviral-naive (ART-naive) HIV-1 infected adults over 48 weeks
    • Aug 13-18; Toronto
    • Eron Jr JJ, Yeni GP, Gathe Jr JC, et al. The KLEAN study: fosamprenavir + ritonavir (FPV/r) versus lopinavir/ritonavir (LPV/r) in antiretroviral-naive (ART-naive) HIV-1 infected adults over 48 weeks. XVI International AIDS; 2006 Aug 13-18; Toronto
    • (2006) XVI International AIDS
    • Eron Jr, J.J.1    Yeni, G.P.2    Gathe Jr, J.C.3
  • 75
    • 1642465026 scopus 로고    scopus 로고
    • Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results
    • Murphy RL, Sanne I, Cahn P, et al. Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results. AIDS 2003; 17 (18): 2603-14
    • (2003) AIDS , vol.17 , Issue.18 , pp. 2603-2614
    • Murphy, R.L.1    Sanne, I.2    Cahn, P.3
  • 76
    • 3342924014 scopus 로고    scopus 로고
    • Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV
    • Squires K, Lazzarin A, Gatell JM, et al. Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV. J Acquir Immune Defic Syndr 2004; 36 (5): 1011-9
    • (2004) J Acquir Immune Defic Syndr , vol.36 , Issue.5 , pp. 1011-1019
    • Squires, K.1    Lazzarin, A.2    Gatell, J.M.3
  • 77
    • 33747141841 scopus 로고    scopus 로고
    • Efficacy and safety of atazanavir-based therapy in antiretroviral naive HIV-1 infected subjects, both with and without ritonavir: 48-week results from AI424-089
    • Feb 5-8, Denver CO
    • Malan N, Krantz E, David N, et al. Efficacy and safety of atazanavir-based therapy in antiretroviral naive HIV-1 infected subjects, both with and without ritonavir: 48-week results from AI424-089. 13th Conference on Retroviruses and Opportunistic Infections; 2006 Feb 5-8, Denver (CO)
    • (2006) 13th Conference on Retroviruses and Opportunistic Infections
    • Malan, N.1    Krantz, E.2    David, N.3
  • 78
    • 38849116827 scopus 로고    scopus 로고
    • The PACTG 1020A protocol: Atazanavir with or without ritonavir in HIV-infected infants, children, and adolescents
    • Feb 25-28; Los Angeles CA
    • Rutstein R, Samson P, Kiser J, et al. The PACTG 1020A protocol: atazanavir with or without ritonavir in HIV-infected infants, children, and adolescents. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Rutstein, R.1    Samson, P.2    Kiser, J.3
  • 79
    • 33746576313 scopus 로고    scopus 로고
    • Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug reSistant patients with Tipranavir (RESIST) studies: An analysis of combined data from two randomised open-label trials
    • Hicks CB, Cahn P, Cooper DA, et al. Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug reSistant patients with Tipranavir (RESIST) studies: an analysis of combined data from two randomised open-label trials. Lancet 2006; 368 (9534): 466-75
    • (2006) Lancet , vol.368 , Issue.9534 , pp. 466-475
    • Hicks, C.B.1    Cahn, P.2    Cooper, D.A.3
  • 80
    • 20544445401 scopus 로고    scopus 로고
    • Efficacy of TMC114/r in 3-class experienced patients with limited treatment options: 24-week planned interim analysis of 2 96-week multinational dose-finding trials
    • Feb 22-25, Boston MA
    • Katlama C, Berger DS, Bellos N, et al. Efficacy of TMC114/r in 3-class experienced patients with limited treatment options: 24-week planned interim analysis of 2 96-week multinational dose-finding trials. 12th Conference on Retroviruses and Opportunistic Infections; 2005 Feb 22-25, Boston (MA)
    • (2005) 12th Conference on Retroviruses and Opportunistic Infections
    • Katlama, C.1    Berger, D.S.2    Bellos, N.3
  • 81
    • 2542452668 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adult and Adolescents, Department of Health and Human Services, Washington, DC
    • Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Department of Health and Human Services 2007; Washington, DC: 1-136
    • (2007) Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents , pp. 1-136
  • 82
    • 0038699906 scopus 로고    scopus 로고
    • Initial therapy with abacavir + lamivudine (ABC + 3TC) combined with efavirenz (NNRTI), amprenavir/ritonavir (PI), or stavudine (NRTI): ESS40001 (CLASS)
    • Bangkok
    • Bartlett JA, Johnson J, Herrera G, et al. Initial therapy with abacavir + lamivudine (ABC + 3TC) combined with efavirenz (NNRTI), amprenavir/ritonavir (PI), or stavudine (NRTI): ESS40001 (CLASS). In: International AIDS, 15th Conference; 2004: Bangkok
    • (2004) International AIDS, 15th Conference
    • Bartlett, J.A.1    Johnson, J.2    Herrera, G.3
  • 83
    • 43849085933 scopus 로고    scopus 로고
    • Riddler SA, Haubrich R, DiRienzo G, et al. A prospective, randomized, phase III trial of NRTI-, PI-, and NNRTI-sparing regimens for initial treatment of HIV-1 infection: ACTG 5142. IXVI International AIDS; 2006 Aug 13-18; Toronto
    • Riddler SA, Haubrich R, DiRienzo G, et al. A prospective, randomized, phase III trial of NRTI-, PI-, and NNRTI-sparing regimens for initial treatment of HIV-1 infection: ACTG 5142. IXVI International AIDS; 2006 Aug 13-18; Toronto
  • 84
    • 43849107474 scopus 로고    scopus 로고
    • MacArthur RD, Novak RM, Peng G, et al. Long-term clinical and immunologic outcomes are similar in HIV-infected persons randomized to NNRTI vs PI vs NNRTI + PI-based antiretroviral regimens as initial therapy: results of the CPCRA 058 FIRST study. XVI International AIDS; 2006 Aug 13-18; Toronto
    • MacArthur RD, Novak RM, Peng G, et al. Long-term clinical and immunologic outcomes are similar in HIV-infected persons randomized to NNRTI vs PI vs NNRTI + PI-based antiretroviral regimens as initial therapy: results of the CPCRA 058 FIRST study. XVI International AIDS; 2006 Aug 13-18; Toronto
  • 85
    • 32644444845 scopus 로고    scopus 로고
    • Antiretroviral activity and safety of lopinavir/ritonavir in protease inhibitor-experienced HIV-infected children with severe-moderate immunodeficiency
    • Resino S, Bellon JM, Munoz-Fernandez MA. Antiretroviral activity and safety of lopinavir/ritonavir in protease inhibitor-experienced HIV-infected children with severe-moderate immunodeficiency. J Antimicrob Chemother 2006; 57 (3): 579-82
    • (2006) J Antimicrob Chemother , vol.57 , Issue.3 , pp. 579-582
    • Resino, S.1    Bellon, J.M.2    Munoz-Fernandez, M.A.3
  • 86
    • 16544384038 scopus 로고    scopus 로고
    • Salvage lopinavir-ritonavir therapy in human immunodeficiency virus-infected children
    • Resino S, Bellon JM, Ramos JT, et al. Salvage lopinavir-ritonavir therapy in human immunodeficiency virus-infected children. Pediatr Infect Dis J 2004; 23 (10): 923-30
    • (2004) Pediatr Infect Dis J , vol.23 , Issue.10 , pp. 923-930
    • Resino, S.1    Bellon, J.M.2    Ramos, J.T.3
  • 87
    • 20444423799 scopus 로고    scopus 로고
    • Immunological changes after highly active antiretroviral therapy with lopinavir-ritonavir in heavily pretreated HIV-infected children
    • Resino S, Galan I, Perez A, et al. Immunological changes after highly active antiretroviral therapy with lopinavir-ritonavir in heavily pretreated HIV-infected children. AIDS Res Hum Retroviruses 2005; 21 (5): 398-406
    • (2005) AIDS Res Hum Retroviruses , vol.21 , Issue.5 , pp. 398-406
    • Resino, S.1    Galan, I.2    Perez, A.3
  • 88
    • 34548203506 scopus 로고    scopus 로고
    • Safety and efficacy of enfuvirtide for 48 weeks as part of an optimized antiretroviral regimen in pediatric human immunodeficiency virus 1-infected patients
    • Wiznia A, Church J, Emmanuel P, et al. Safety and efficacy of enfuvirtide for 48 weeks as part of an optimized antiretroviral regimen in pediatric human immunodeficiency virus 1-infected patients. Pediatr Infect Dis J 2007; 26 (9): 799-805
    • (2007) Pediatr Infect Dis J , vol.26 , Issue.9 , pp. 799-805
    • Wiznia, A.1    Church, J.2    Emmanuel, P.3
  • 89
    • 0038576281 scopus 로고    scopus 로고
    • Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
    • Lalezari JP, Henry K, O'Hearn M, et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003; 348 (22): 2175-85
    • (2003) N Engl J Med , vol.348 , Issue.22 , pp. 2175-2185
    • Lalezari, J.P.1    Henry, K.2    O'Hearn, M.3
  • 90
    • 27944473910 scopus 로고    scopus 로고
    • Durable efficacy of enfuvirtide over 48 weeks in heavily treatment-experienced HIV-1-infected patients in the T-20 versus Optimized background Regimen Only 1 and 2 clinical trials
    • Nelson M, Arasteh K, Clotet B, et al. Durable efficacy of enfuvirtide over 48 weeks in heavily treatment-experienced HIV-1-infected patients in the T-20 versus Optimized background Regimen Only 1 and 2 clinical trials. J Acquir Immune Defic Syndr 2005; 40 (4): 404-12
    • (2005) J Acquir Immune Defic Syndr , vol.40 , Issue.4 , pp. 404-412
    • Nelson, M.1    Arasteh, K.2    Clotet, B.3
  • 91
    • 34147134958 scopus 로고    scopus 로고
    • Efficacy and safety of etravirine (TMC125) in patients with highly resistant HIV-1: Primary 24-week analysis
    • Nadler JP, Berger DS, Blick G, et al. Efficacy and safety of etravirine (TMC125) in patients with highly resistant HIV-1: primary 24-week analysis. AIDS 2007; 21 (6): F1-10
    • (2007) AIDS , vol.21 , Issue.6
    • Nadler, J.P.1    Berger, D.S.2    Blick, G.3
  • 92
    • 12144287763 scopus 로고    scopus 로고
    • An open-label assessment of TMC 125: A new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRTI resistance
    • Gazzard BG, Pozniak AL, Rosenbaum W, et al. An open-label assessment of TMC 125: a new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRTI resistance. AIDS 2003; 17 (18): F49-54
    • (2003) AIDS , vol.17 , Issue.18
    • Gazzard, B.G.1    Pozniak, A.L.2    Rosenbaum, W.3
  • 93
    • 12144289848 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects
    • Gruzdev B, Rakhmanova A, Doubovskaya E, et al. A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects. AIDS 2003; 17 (17): 2487-94
    • (2003) AIDS , vol.17 , Issue.17 , pp. 2487-2494
    • Gruzdev, B.1    Rakhmanova, A.2    Doubovskaya, E.3
  • 94
    • 43849086642 scopus 로고    scopus 로고
    • Cohen C, Steinhart CR, Ward D, et al. Efficacy and safety results at 48 weeks with the novel NNRTI, TMC125, and impact of baseline resistance on the virologic response in study TMC125, and impact of baseline resistance on the virologic response in study TMC125-C223. XVI International AIDS; 2006 Aug 13-18; Toronto
    • Cohen C, Steinhart CR, Ward D, et al. Efficacy and safety results at 48 weeks with the novel NNRTI, TMC125, and impact of baseline resistance on the virologic response in study TMC125, and impact of baseline resistance on the virologic response in study TMC125-C223. XVI International AIDS; 2006 Aug 13-18; Toronto
  • 95
    • 20844435865 scopus 로고    scopus 로고
    • Effect of baseline genotype on response to tipranavir/ritonavir compared with standard-of-care comparator in treatment-experienced patients: The phase 3 RESIST-1 and -2 trials
    • Feb 22-25, Boston MA
    • Schapiro JM, Cahn P, Trottier B, et al. Effect of baseline genotype on response to tipranavir/ritonavir compared with standard-of-care comparator in treatment-experienced patients: the phase 3 RESIST-1 and -2 trials. 12th Conference on Retroviruses and Opportunistic Infections; 2005 Feb 22-25, Boston (MA)
    • (2005) 12th Conference on Retroviruses and Opportunistic Infections
    • Schapiro, J.M.1    Cahn, P.2    Trottier, B.3
  • 96
    • 33750338185 scopus 로고    scopus 로고
    • Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir
    • Baxter JD, Schapiro JM, Boucher CA, et al. Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol 2006; 80 (21): 10794-801
    • (2006) J Virol , vol.80 , Issue.21 , pp. 10794-10801
    • Baxter, J.D.1    Schapiro, J.M.2    Boucher, C.A.3
  • 97
    • 33747019824 scopus 로고    scopus 로고
    • Population pharmacokinetic (PK) assessment of systemic steady-state tipranavir (TPV) concentrations for HIV + pediatric patients administered tipranavir/ritonavir (TPV/r 290/115 mg/m2 BID BI1192.14 and PACTG 1051 study team)
    • Feb 5-8, Denver CO
    • Sabo JP, Cahn P, Della Negra M, et al. Population pharmacokinetic (PK) assessment of systemic steady-state tipranavir (TPV) concentrations for HIV + pediatric patients administered tipranavir/ritonavir (TPV/r 290/115 mg/m2 BID BI1192.14 and PACTG 1051 study team). 13th Conference on Retroviruses and Opportunistic Infections; 2006 Feb 5-8, Denver (CO)
    • (2006) 13th Conference on Retroviruses and Opportunistic Infections
    • Sabo, J.P.1    Cahn, P.2    Della Negra, M.3
  • 98
    • 33747122666 scopus 로고    scopus 로고
    • Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel
    • Hammer SM, Saag MS, Schechter M, et al. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. JAMA 2006; 296 (7): 827-43
    • (2006) JAMA , vol.296 , Issue.7 , pp. 827-843
    • Hammer, S.M.1    Saag, M.S.2    Schechter, M.3
  • 99
    • 34047207229 scopus 로고    scopus 로고
    • Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: A pooled subgroup analysis of data from two randomised trials
    • Clotet B, Bellos N, Molina JM, et al. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. Lancet 2007; 369 (9568): 1169-78
    • (2007) Lancet , vol.369 , Issue.9568 , pp. 1169-1178
    • Clotet, B.1    Bellos, N.2    Molina, J.M.3
  • 100
    • 26944437399 scopus 로고    scopus 로고
    • Pharmacokinetics and 24-week efficacy/safety of dual boosted saquinavir/lopinavir/ritonavir in nucleoside-pretreated children
    • Ananworanich J, Kosalaraksa P, Hill A, et al. Pharmacokinetics and 24-week efficacy/safety of dual boosted saquinavir/lopinavir/ritonavir in nucleoside-pretreated children. Pediatr Infect Dis J 2005; 24 (10): 874-9
    • (2005) Pediatr Infect Dis J , vol.24 , Issue.10 , pp. 874-879
    • Ananworanich, J.1    Kosalaraksa, P.2    Hill, A.3
  • 101
    • 34250310413 scopus 로고    scopus 로고
    • Combination antiretroviral therapy without a nucleoside reverse transcriptase inhibitor: Experience from 334 patients in three cohorts
    • Calmy A, Petoumenos K, Lewden C, et al. Combination antiretroviral therapy without a nucleoside reverse transcriptase inhibitor: experience from 334 patients in three cohorts. HIV Med 2007; 8 (3): 171-80
    • (2007) HIV Med , vol.8 , Issue.3 , pp. 171-180
    • Calmy, A.1    Petoumenos, K.2    Lewden, C.3
  • 102
    • 33846596702 scopus 로고    scopus 로고
    • Randomized open-label trial of two simplified, class-sparing regimens following a first suppressive three or four-drug regimen
    • Fischl MA, Collier AC, Mukherjee AL, et al. Randomized open-label trial of two simplified, class-sparing regimens following a first suppressive three or four-drug regimen. AIDS 2007; 21 (3): 325-33
    • (2007) AIDS , vol.21 , Issue.3 , pp. 325-333
    • Fischl, M.A.1    Collier, A.C.2    Mukherjee, A.L.3
  • 103
    • 0042628231 scopus 로고    scopus 로고
    • Lopinavir/ritovinar plus saquinavir in salvage therapy: Pharmacokinetics, tolerability and efficacy
    • La Porte CJ, Wasmuth JC, Schneider K, et al. Lopinavir/ritovinar plus saquinavir in salvage therapy: pharmacokinetics, tolerability and efficacy. AIDS 2003; 17: 1700-2
    • (2003) AIDS , vol.17 , pp. 1700-1702
    • La Porte, C.J.1    Wasmuth, J.C.2    Schneider, K.3
  • 104
    • 25144451316 scopus 로고    scopus 로고
    • Virologic and immunologic response to a boosted double-protease inhibitor-based therapy in highly pretreated HIV-1-infected patients
    • Smith GH, Boulassel MR, Klien M, et al. Virologic and immunologic response to a boosted double-protease inhibitor-based therapy in highly pretreated HIV-1-infected patients. HIV Clin Trials 2005; 6: 63-72
    • (2005) HIV Clin Trials , vol.6 , pp. 63-72
    • Smith, G.H.1    Boulassel, M.R.2    Klien, M.3
  • 105
    • 33746266719 scopus 로고    scopus 로고
    • Approach to salvage antiretroviral therapy in heavily antiretroviral-experienced HIV-positive adults
    • Temesgen Z, Cainelli F, Poeschla EM, et al. Approach to salvage antiretroviral therapy in heavily antiretroviral-experienced HIV-positive adults. Lancet Infect Dis 2006; 6 (8): 496-507
    • (2006) Lancet Infect Dis , vol.6 , Issue.8 , pp. 496-507
    • Temesgen, Z.1    Cainelli, F.2    Poeschla, E.M.3
  • 106
    • 0034723439 scopus 로고    scopus 로고
    • Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
    • Hazuda DJ, Felock P, Witmer M, et al. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science 2000; 287 (5453): 646-50
    • (2000) Science , vol.287 , Issue.5453 , pp. 646-650
    • Hazuda, D.J.1    Felock, P.2    Witmer, M.3
  • 107
    • 34248199833 scopus 로고    scopus 로고
    • The HIV integrase inhibitor GS-9137 demonstrates potent antiretroviral activity in treatment-experienced patients
    • Feb 25-28; Los Angeles CA
    • Zolopa A, Mullen M, Berger DS, et al. The HIV integrase inhibitor GS-9137 demonstrates potent antiretroviral activity in treatment-experienced patients. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Zolopa, A.1    Mullen, M.2    Berger, D.S.3
  • 110
    • 24344496912 scopus 로고    scopus 로고
    • Emerging drug targets for antiretroviral therapy
    • Reeves JD, Piefer AJ. Emerging drug targets for antiretroviral therapy. Drugs 2005; 65 (13): 1747-66
    • (2005) Drugs , vol.65 , Issue.13 , pp. 1747-1766
    • Reeves, J.D.1    Piefer, A.J.2
  • 111
    • 33847237614 scopus 로고    scopus 로고
    • Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry
    • Westby M, Smith-Burchnell C, Mori J, et al. Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry. J Virol 2007; 81 (5): 2359-71
    • (2007) J Virol , vol.81 , Issue.5 , pp. 2359-2371
    • Westby, M.1    Smith-Burchnell, C.2    Mori, J.3
  • 112
    • 27644510382 scopus 로고    scopus 로고
    • Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
    • Dorr P, Westby M, Dobbs S, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob Agents Chemother 2005; 49 (11): 4721-32
    • (2005) Antimicrob Agents Chemother , vol.49 , Issue.11 , pp. 4721-4732
    • Dorr, P.1    Westby, M.2    Dobbs, S.3
  • 113
    • 30744447460 scopus 로고    scopus 로고
    • Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1
    • Fatkenheuer G, Pozniak AL, Johnson MA, et al. Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1. Nat Med 2005; 11 (11): 1170-2
    • (2005) Nat Med , vol.11 , Issue.11 , pp. 1170-1172
    • Fatkenheuer, G.1    Pozniak, A.L.2    Johnson, M.A.3
  • 114
    • 34249089383 scopus 로고    scopus 로고
    • Efficacy and safety of maraviroc plus optimized background therapy in viremic ART-experienced patients infected with CCR5-tropic HIV-1: 24-week results of a phase 2b/3 study in the US and Canada
    • Feb 25-28; Los Angeles CA
    • Lalezari JP, Goodrich J, DeJesus E, et al. Efficacy and safety of maraviroc plus optimized background therapy in viremic ART-experienced patients infected with CCR5-tropic HIV-1: 24-week results of a phase 2b/3 study in the US and Canada. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Lalezari, J.P.1    Goodrich, J.2    DeJesus, E.3
  • 115
    • 34249075565 scopus 로고    scopus 로고
    • Efficacy and safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results
    • Feb 25-28; Los Angeles CA
    • Nelson M, Fatkenheuer G, Konourina I, et al. Efficacy and safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results. 14th Conference on Retroviruses and Opportunistic Infections; 2007 Feb 25-28; Los Angeles (CA)
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Nelson, M.1    Fatkenheuer, G.2    Konourina, I.3
  • 116
    • 34250205194 scopus 로고    scopus 로고
    • Drug resistant HIV
    • Hatano H, Deeks SG. Drug resistant HIV. BMJ 2007; 334 (7604): 1124-5
    • (2007) BMJ , vol.334 , Issue.7604 , pp. 1124-1125
    • Hatano, H.1    Deeks, S.G.2
  • 117
    • 43849083720 scopus 로고    scopus 로고
    • Regulation (EC) no 1901/2006 of the European Parliament and of the Council of 12 December 2006 on medicinal products for paediatric use and amending regulation (EEC) No. 1768/92, Directive 2001/20/EC, Directive 2001/83/EC and Regulation (EC) No. 726/2004. Official Journal of the European Union [online]. Available from URL: http://eurlex.europa.eu/LexUriServ/ LexUriServ.do?uri=CONSLEG:2006R1901:20070126:EN: PDF [Accessed 2008 Apr 30]
    • Regulation (EC) no 1901/2006 of the European Parliament and of the Council of 12 December 2006 on medicinal products for paediatric use and amending regulation (EEC) No. 1768/92, Directive 2001/20/EC, Directive 2001/83/EC and Regulation (EC) No. 726/2004. Official Journal of the European Union [online]. Available from URL: http://eurlex.europa.eu/LexUriServ/ LexUriServ.do?uri=CONSLEG:2006R1901:20070126:EN: PDF [Accessed 2008 Apr 30]


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.