Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 10, 2008, Pages 5653-5664

  Wentland, Mark P ^a   Sun, Xufeng ^a   Cohen, Dana J ^b   Bidlack, Jean M ^b  

^a Research Rensselaer Polytechnic Institute   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Opioid; Pharmacophore hypothesis; SAR

Indexed keywords

8 CARBOXAMIDOCYCLAZOCINE DERIVATIVE; BENZAZOCINE DERIVATIVE; OPIATE RECEPTOR; PYRIDONE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRIMIDINONE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; AZOCINES; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; CYCLAZOCINE; DRUG DESIGN; MOLECULAR CONFORMATION; RECEPTORS, OPIOID; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 43749107546     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.03.066     Document Type: Article

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