Synthesis and opioid receptor binding properties of a highly potent 4-hydroxy analogue of naltrexone

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 8, 2005, Pages 2107-2110

  Wentland, Mark P ^a   Lu, Qun ^a   Lou, Rongliang ^a   Bu, Yigong ^a   Knapp, Brian I ^b   Bidlack, Jean M ^b  

^a Research Rensselaer Polytechnic Institute   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Opiate; SAR

Indexed keywords

AMIDE; NALTREXONE; OPIATE RECEPTOR;

ARTICLE; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 15944415141     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.032     Document Type: Article

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