Redefining the structure-activity relationships of 2,6-methano-3- benzazocines. 4. Opioid receptor binding properties of 8-[n-(4′-phenyl)- phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine

Journal of Medicinal Chemistry

Volumn 49, Issue 18, 2006, Pages 5635-5639

  Wentland, Mark P ^a   VanAlstine, Melissa ^a   Kucejko, Robert ^a   Lou, Rongliang ^a   Cohen, Dana J ^b   Parkhill, Amy L ^b   Bidlack, Jean M ^b  

^a Research Rensselaer Polytechnic Institute   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 METHANO 3 BENZAZOCINE; 8 [N (4' PHENYL)PHENETHYL)CARBOXAMIDE DERIVATIVE; CYCLAZOCINE; DELTA OPIATE RECEPTOR; ETHYLKETAZOCINE; G PROTEIN COUPLED RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; DEMETHYLATION; DRUG RECEPTOR BINDING; ENANTIOMER; ENANTIOSELECTIVITY; GUINEA PIG; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR RECOGNITION; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLAZOCINE; ETHYLKETOCYCLAZOCINE; HUMANS; HYDROPHOBICITY; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748531857     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060278n     Document Type: Article

References (9)

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