In vivo intervertebral disc remodeling: Kinetics of mRNA expression in response to a single loading event

Journal of Orthopaedic Research

Volumn 26, Issue 5, 2008, Pages 579-588

  MacLean, Jeffrey J ^a   Roughley, Peter J ^b   Monsey, Robert D ^a   Alini, Mauro ^c   Iatridis, James C ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b SHRINERS HOSPITAL FOR CHILDREN   (Canada)

^c AO RESEARCH INSTITUTE   (Switzerland)

Author keywords

Animal model; Intervertebral disc; Mechano biology; mRNA kinetics; Real time RT PCR

Indexed keywords

ADAMTS 4 PROTEIN; AGGRECAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGENASE 3; GELATINASE A; MESSENGER RNA; METALLOPROTEINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; SCLEROPROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REMODELING; COLLAGEN METABOLISM; COMPRESSIVE STRENGTH; IN VIVO STUDY; INTERVERTEBRAL DISK; MECHANICAL STIMULATION; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; UPREGULATION; WEIGHT BEARING; ANIMAL; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WISTAR RAT;

ANIMALS; EXTRACELLULAR MATRIX PROTEINS; INTERVERTEBRAL DISK; METALLOENDOPEPTIDASES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASES; WEIGHT-BEARING;

EID: 43649089910     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20560     Document Type: Article

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