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For a recent, comprehensive review, see: Enders, D.; Niemeier, O.; Henseler, A. Chem. Rev. 2007, 107, 5606-5655.
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For recent reviews, see: (a) Johnson, J. S. Angew. Chem., Int. Ed. 2003, 42, 2534-2536.
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Johnson, J.S.1
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4
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For the first reports of this concept, see: a
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For the first reports of this concept, see: (a) Chow, K. Y.-C; Bode, J. W. J. Am. Chem. Soc. 2004,126, 8126-8127.
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(b)Reynolds, N. T.; Read de Alaniz, J.; Rovis, T. J. Am. Chem. Soc. 2004, 126, 9518-9519.
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(c)Chiang, P.-C; Kaeobamrung, J.; Bode, J. W. J. Am. Chem. Soc. 2007, 129, 3520-3521.
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(a)Sohn, S. S.; Rosen, E. L.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 14370-14371.
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(b)Burstein, C; Glorius, F. Angew. Chem., Int. Ed. 2004, 43, 6205 -6208.
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(a)Kerr, M. S.; Read de Alaniz, J.; Rovis, T. J. Am. Chem. Soc. 2002, 124, 10298-10299.
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21
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0037453328
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For an excellent review of chiral N-heterocyclic carbenes, see
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For an excellent review of chiral N-heterocyclic carbenes, see: Perry, M. C; Burgess, K. Tetrahedron: Asymmetry 2003, 14, 951-961.
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Tetrahedron: Asymmetry
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Nyce, G. W.; Csihony, S.; Waymouth, R. M.; Hedrick, J. L. Chem-Eur. J. 2004, 10, 4073 -4079.
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Fürstner, A.; Alcarazo, M.; César, V.; Lehmann, C. W. Chem. Commun. 2006, 2176-2178.
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Fürstner, A.1
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Lehmann, C.W.4
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27
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58149192119
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4. Further details on the development of this route and its use to prepare a range of N- substituted derivatives is the subject of forthcoming full account.
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4. Further details on the development of this route and its use to prepare a range of N- substituted derivatives is the subject of forthcoming full account.
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28
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58149198167
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The most common achiral imidazolium salt employed for homoeno-late based annulations is IMesCl
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The most common achiral imidazolium salt employed for homoeno-late based annulations is IMesCl:
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29
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58149181956
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4 was employed. When DBU was used as base, the aldehyde was consumed but the dihydropyranone product was not observed.
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4 was employed. When DBU was used as base, the aldehyde was consumed but the dihydropyranone product was not observed.
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31
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34247874549
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For another racemic variant, see
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(b)For another racemic variant, see: Chan, A.; Scheidt, K. J. Am. Chem. Soc. 2007, 129, 5334-5335.
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(2007)
J. Am. Chem. Soc
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Chan, A.1
Scheidt, K.2
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38649133799
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DOI: 10.1039/b715733a
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Nair, V.; Pattoorpadi Babu, B.; Vellalath, S.; Suresh, E. Chem. Commun. 2008, DOI: 10.1039/b715733a.
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Chem. Commun
, vol.2008
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Nair, V.1
Pattoorpadi Babu, B.2
Vellalath, S.3
Suresh, E.4
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