Organocatalyzed conjugate umpolung of α,β-unsaturated aldehydes for the synthesis of γ-butyrolactones

Angewandte Chemie - International Edition

Volumn 43, Issue 45, 2004, Pages 6205-6208

  Burstein, Christian ^a   Glorius, Frank ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

Aldehydes; Carbene; Heterocycles; Organocatalysis; Umpolung

Indexed keywords

ALDEHYDES; CATALYSIS; CATALYSTS; CHEMICAL ANALYSIS; SYNTHESIS (CHEMICAL);

CONJUGATE UMPOLUNG; HOMOENOLATE; ORGANOCATALYSIS; UNSATURATED ALDEHYDES;

UNSATURATED COMPOUNDS;

ALDEHYDE; CARBENE; GAMMA BUTYROLACTONE; HETEROCYCLIC COMPOUND; KETONE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; CRYSTAL STRUCTURE; CRYSTALLIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY; SYNTHESIS;

4-BUTYROLACTONE; ALDEHYDES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE;

EID: 10044249952     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200461572     Document Type: Article

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44. Preliminary experiments show that other ketones can be used as electrophiles and alkyl-substituted α,β-unsaturated aldehydes can be used as nucleophiles after conjugate umpolung; we will report on these results in due course.
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