Interleukin-1β up-regulates RGS4 through the canonical IKK2/IκBα/NF-κB pathway in rabbit colonic smooth muscle

Biochemical Journal

Volumn 412, Issue 1, 2008, Pages 34-43

  Hu, Wenhui ^a   Li, Fang ^a   Mahavadi, Sunila ^a   Murthy, Karnam S ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Interleukin 1 (IL 1 ); Intestinal smooth muscle; Nuclear factor B (NF B); Phospholipase C; Regulator of G protein signaling 4 (RGS4); Small interfering RNA

Indexed keywords

BINDING SITES; DNA; MUSCLE; SIGNAL TRANSDUCTION; TRANSCRIPTION;

ACETYLCHOLINE; NUCLEAR TRANSLOCATION;

GENETIC ENGINEERING;

6 AMINO 4 (4 PHENOXYPHENYLETHYLAMINO)QUINAZOLINE; ACETYLCHOLINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DACTINOMYCIN; ENZYME INHIBITOR; ESTERASE; I KAPPA B ALPHA; I KAPPA B KINASE; I KAPPA B KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PHOSPHOLIPASE C BETA; RGS4 PROTEIN; SERINE; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; I KAPPA B; MESSENGER RNA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; RGS PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG ANTAGONISM; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; GENE TARGETING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; UPREGULATION; ANIMAL; CELL CULTURE; COLON; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUSCLE CONTRACTION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ORYCTOLAGUS CUNICULUS;

ACETYLCHOLINE; ANIMALS; CELLS, CULTURED; COLON; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; PHOSPHOLIPASE C BETA; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RABBITS; RGS PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION; UP-REGULATION;

EID: 43549113351     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20080042     Document Type: Article

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