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Volumn 401, Issue 1-2, 2007, Pages 46-60

Full length cloning and expression analysis of splice variants of regulator of G-protein signaling RGS4 in human and murine brain

Author keywords

Alternative promoter; Alternative splicing; Alzheimer's disease; Prefrontal cortex; Schizophrenia; Transcriptional regulation

Indexed keywords

AMINO ACID; RGS4 PROTEIN;

EID: 34548475785     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.07.002     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 14844284614 scopus 로고    scopus 로고
    • Two promoters control the mouse Nmp4/CIZ transcription factor gene
    • Alvarez M., Shah R., Rhodes S.J., and Bidwell J.P. Two promoters control the mouse Nmp4/CIZ transcription factor gene. Gene 347 (2005) 43-54
    • (2005) Gene , vol.347 , pp. 43-54
    • Alvarez, M.1    Shah, R.2    Rhodes, S.J.3    Bidwell, J.P.4
  • 3
    • 0029861417 scopus 로고    scopus 로고
    • The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
    • Berman D.M., Kozasa T., and Gilman A.G. The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J. Biol. Chem. 271 (1996) 27209-27212
    • (1996) J. Biol. Chem. , vol.271 , pp. 27209-27212
    • Berman, D.M.1    Kozasa, T.2    Gilman, A.G.3
  • 5
    • 0034703054 scopus 로고    scopus 로고
    • Novel alternative splicing and nuclear localization of human RGS12 gene products
    • Chatterjee T.K., and Fisher R.A. Novel alternative splicing and nuclear localization of human RGS12 gene products. J. Biol. Chem. 275 (2000) 29660-29671
    • (2000) J. Biol. Chem. , vol.275 , pp. 29660-29671
    • Chatterjee, T.K.1    Fisher, R.A.2
  • 6
    • 0042664189 scopus 로고    scopus 로고
    • Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants
    • Chatterjee T.K., Liu Z., and Fisher R.A. Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants. J. Biol. Chem. 278 (2003) 30261-30271
    • (2003) J. Biol. Chem. , vol.278 , pp. 30261-30271
    • Chatterjee, T.K.1    Liu, Z.2    Fisher, R.A.3
  • 7
    • 3342875632 scopus 로고    scopus 로고
    • Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families
    • Chen X., et al. Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families. Am. J. Med. Genet. B Neuropsychiatr. Genet. 129 (2004) 23-26
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.129 , pp. 23-26
    • Chen, X.1
  • 8
    • 71749085915 scopus 로고    scopus 로고
    • Association and linkage analyses of RGS4 polymorphisms in schizophrenia
    • Chowdari K.V., et al. Association and linkage analyses of RGS4 polymorphisms in schizophrenia. Hum. Mol. Genet. 11 (2002) 1373-1380
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1373-1380
    • Chowdari, K.V.1
  • 9
    • 12944316462 scopus 로고    scopus 로고
    • Association and linkage analysis of RGS4 polymorphisms with schizophrenia and bipolar disorder in Brazil
    • Cordeiro Q., Talkowski M.E., Chowdari K.V., Wood J., Nimgaonkar V., and Vallada H. Association and linkage analysis of RGS4 polymorphisms with schizophrenia and bipolar disorder in Brazil. Genes Brain Behav. 4 (2005) 45-50
    • (2005) Genes Brain Behav. , vol.4 , pp. 45-50
    • Cordeiro, Q.1    Talkowski, M.E.2    Chowdari, K.V.3    Wood, J.4    Nimgaonkar, V.5    Vallada, H.6
  • 11
    • 33244496656 scopus 로고    scopus 로고
    • Alzheimer's disease: mRNA expression profiles of multiple patients show alterations of genes involved with calcium signaling
    • Emilsson L., Saetre P., and Jazin E. Alzheimer's disease: mRNA expression profiles of multiple patients show alterations of genes involved with calcium signaling. Neurobiol. Dis. 21 (2006) 618-625
    • (2006) Neurobiol. Dis. , vol.21 , pp. 618-625
    • Emilsson, L.1    Saetre, P.2    Jazin, E.3
  • 12
    • 31144466836 scopus 로고    scopus 로고
    • Low mRNA levels of RGS4 splice variants in Alzheimer's disease: association between a rare haplotype and decreased mRNA expression
    • Emilsson L., Saetre P., and Jazin E. Low mRNA levels of RGS4 splice variants in Alzheimer's disease: association between a rare haplotype and decreased mRNA expression. Synapse 59 (2006) 173-176
    • (2006) Synapse , vol.59 , pp. 173-176
    • Emilsson, L.1    Saetre, P.2    Jazin, E.3
  • 13
    • 3042604602 scopus 로고    scopus 로고
    • Regional expression of RGS4 mRNA in human brain
    • Erdely H.A., et al. Regional expression of RGS4 mRNA in human brain. Eur. J. Neurosci. 19 (2004) 3125-3128
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 3125-3128
    • Erdely, H.A.1
  • 14
    • 0037135521 scopus 로고    scopus 로고
    • Natural trans-spliced mRNAs are generated from the human estrogen receptor-alpha (hER alpha) gene
    • Flouriot G., Brand H., Seraphin B., and Gannon F. Natural trans-spliced mRNAs are generated from the human estrogen receptor-alpha (hER alpha) gene. J. Biol. Chem. 277 (2002) 26244-26251
    • (2002) J. Biol. Chem. , vol.277 , pp. 26244-26251
    • Flouriot, G.1    Brand, H.2    Seraphin, B.3    Gannon, F.4
  • 15
    • 0035724427 scopus 로고    scopus 로고
    • Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysis
    • Giudice A., et al. Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysis. Cytogenet. Cell Genet. 94 (2001) 216-224
    • (2001) Cytogenet. Cell Genet. , vol.94 , pp. 216-224
    • Giudice, A.1
  • 17
    • 0027253487 scopus 로고
    • Isolation and characterization of a novel B cell activation gene
    • Hong J.X., Wilson G.L., Fox C.H., and Kehrl J.H. Isolation and characterization of a novel B cell activation gene. J. Immunol. 150 (1993) 3895-3904
    • (1993) J. Immunol. , vol.150 , pp. 3895-3904
    • Hong, J.X.1    Wilson, G.L.2    Fox, C.H.3    Kehrl, J.H.4
  • 18
    • 33644801773 scopus 로고    scopus 로고
    • Alternative initiation and splicing in dicer gene expression in human breast cells
    • Irvin-Wilson C.V., and Chaudhuri G. Alternative initiation and splicing in dicer gene expression in human breast cells. Breast Cancer Res. 7 (2005) R563-R569
    • (2005) Breast Cancer Res. , vol.7
    • Irvin-Wilson, C.V.1    Chaudhuri, G.2
  • 19
    • 0035825662 scopus 로고    scopus 로고
    • Functional annotation of a full-length mouse cDNA collection
    • Kawai J., et al. Functional annotation of a full-length mouse cDNA collection. Nature 409 (2001) 685-690
    • (2001) Nature , vol.409 , pp. 685-690
    • Kawai, J.1
  • 20
    • 0029762061 scopus 로고    scopus 로고
    • Importance of the two interferon-stimulated response element (ISRE) sequences in the regulation of the human indoleamine 2,3-dioxygenase gene
    • Konan K.V., and Taylor M.W. Importance of the two interferon-stimulated response element (ISRE) sequences in the regulation of the human indoleamine 2,3-dioxygenase gene. J. Biol. Chem. 271 (1996) 19140-19145
    • (1996) J. Biol. Chem. , vol.271 , pp. 19140-19145
    • Konan, K.V.1    Taylor, M.W.2
  • 21
    • 1342264196 scopus 로고    scopus 로고
    • Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system
    • Larminie C., et al. Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system. Brain Res. Mol. Brain Res. 122 (2004) 24-34
    • (2004) Brain Res. Mol. Brain Res. , vol.122 , pp. 24-34
    • Larminie, C.1
  • 22
    • 0035976763 scopus 로고    scopus 로고
    • Genes differentially expressed in the kindled mouse brain
    • Liang D., and Seyfried T.N. Genes differentially expressed in the kindled mouse brain. Brain Res. Mol. Brain Res. 96 (2001) 94-102
    • (2001) Brain Res. Mol. Brain Res. , vol.96 , pp. 94-102
    • Liang, D.1    Seyfried, T.N.2
  • 23
    • 11244339945 scopus 로고    scopus 로고
    • Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1)
    • Liang S.H., Hassett C., and Omiecinski C.J. Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1). Mol. Pharmacol. 67 (2005) 220-230
    • (2005) Mol. Pharmacol. , vol.67 , pp. 220-230
    • Liang, S.H.1    Hassett, C.2    Omiecinski, C.J.3
  • 24
    • 13444292030 scopus 로고    scopus 로고
    • Identification of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues
    • Liang Y., et al. Identification of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues. FEBS J. 272 (2005) 791-799
    • (2005) FEBS J. , vol.272 , pp. 791-799
    • Liang, Y.1
  • 25
    • 0035061298 scopus 로고    scopus 로고
    • Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia
    • Mirnics K., Middleton F.A., Stanwood G.D., Lewis D.A., and Levitt P. Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol. Psychiatry 6 (2001) 293-301
    • (2001) Mol. Psychiatry , vol.6 , pp. 293-301
    • Mirnics, K.1    Middleton, F.A.2    Stanwood, G.D.3    Lewis, D.A.4    Levitt, P.5
  • 26
    • 0034459468 scopus 로고    scopus 로고
    • Upstream open reading frames as regulators of mRNA translation
    • Morris D.R., and Geballe A.P. Upstream open reading frames as regulators of mRNA translation. Mol. Cell Biol. 20 (2000) 8635-8642
    • (2000) Mol. Cell Biol. , vol.20 , pp. 8635-8642
    • Morris, D.R.1    Geballe, A.P.2
  • 27
    • 0942268965 scopus 로고    scopus 로고
    • Confirming RGS4 as a susceptibility gene for schizophrenia
    • Morris D.W., et al. Confirming RGS4 as a susceptibility gene for schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 125 (2004) 50-53
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.125 , pp. 50-53
    • Morris, D.W.1
  • 28
    • 0037211793 scopus 로고    scopus 로고
    • Differences in regional and subcellular localization of G(q/11) and RGS4 protein levels in Alzheimer's disease: correlation with muscarinic M1 receptor binding parameters
    • Muma N.A., Mariyappa R., Williams K., and Lee J.M. Differences in regional and subcellular localization of G(q/11) and RGS4 protein levels in Alzheimer's disease: correlation with muscarinic M1 receptor binding parameters. Synapse 47 (2003) 58-65
    • (2003) Synapse , vol.47 , pp. 58-65
    • Muma, N.A.1    Mariyappa, R.2    Williams, K.3    Lee, J.M.4
  • 29
    • 17844404583 scopus 로고    scopus 로고
    • Large-scale analysis of human alternative protein isoforms: pattern classification and correlation with subcellular localization signals
    • Nakao M., Barrero R.A., Mukai Y., Motono C., Suwa M., and Nakai K. Large-scale analysis of human alternative protein isoforms: pattern classification and correlation with subcellular localization signals. Nucleic Acids Res. 33 (2005) 2355-2363
    • (2005) Nucleic Acids Res. , vol.33 , pp. 2355-2363
    • Nakao, M.1    Barrero, R.A.2    Mukai, Y.3    Motono, C.4    Suwa, M.5    Nakai, K.6
  • 30
    • 14944358603 scopus 로고    scopus 로고
    • Expression of the plasma prekallikrein gene: utilization of multiple transcription start sites and alternative promoter regions
    • Neth P., Arnhold M., Sidarovich V., Bhoola K.D., and Fink E. Expression of the plasma prekallikrein gene: utilization of multiple transcription start sites and alternative promoter regions. Biol. Chem. 386 (2005) 101-109
    • (2005) Biol. Chem. , vol.386 , pp. 101-109
    • Neth, P.1    Arnhold, M.2    Sidarovich, V.3    Bhoola, K.D.4    Fink, E.5
  • 31
    • 0033562392 scopus 로고    scopus 로고
    • Region-specific regulation of RGS4 (Regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: in vivo and in vitro studies
    • Ni Y.G., Gold S.J., Iredale P.A., Terwilliger R.Z., Duman R.S., and Nestler E.J. Region-specific regulation of RGS4 (Regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: in vivo and in vitro studies. J. Neurosci. 19 (1999) 3674-3680
    • (1999) J. Neurosci. , vol.19 , pp. 3674-3680
    • Ni, Y.G.1    Gold, S.J.2    Iredale, P.A.3    Terwilliger, R.Z.4    Duman, R.S.5    Nestler, E.J.6
  • 32
    • 27744479194 scopus 로고    scopus 로고
    • Involvement of N-terminally extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis
    • Okada T., et al. Involvement of N-terminally extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis. J. Biol. Chem. 280 (2005) 36318-36325
    • (2005) J. Biol. Chem. , vol.280 , pp. 36318-36325
    • Okada, T.1
  • 33
    • 7444253965 scopus 로고    scopus 로고
    • Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs
    • Oyama M., et al. Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs. Genome Res. 14 (2004) 2048-2052
    • (2004) Genome Res. , vol.14 , pp. 2048-2052
    • Oyama, M.1
  • 34
    • 4644248763 scopus 로고    scopus 로고
    • COMT haplotypes suggest P2 promoter region relevance for schizophrenia
    • Palmatier M.A., et al. COMT haplotypes suggest P2 promoter region relevance for schizophrenia. Mol. Psychiatry 9 (2004) 859-870
    • (2004) Mol. Psychiatry , vol.9 , pp. 859-870
    • Palmatier, M.A.1
  • 36
    • 0033559843 scopus 로고    scopus 로고
    • Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene
    • Rahman Z., et al. Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. J. Neurosci. 19 (1999) 2016-2026
    • (1999) J. Neurosci. , vol.19 , pp. 2016-2026
    • Rahman, Z.1
  • 37
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins
    • Ross E.M., and Wilkie T.M. GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu. Rev. Biochem. 69 (2000) 795-827
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 38
    • 0037162557 scopus 로고    scopus 로고
    • Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling
    • Saitoh O., et al. Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 10138-10143
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 10138-10143
    • Saitoh, O.1
  • 39
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw G., and Kamen R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46 (1986) 659-667
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 40
    • 20844449699 scopus 로고    scopus 로고
    • The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation
    • Sims-Mourtada J.C., et al. The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation. DNA Cell Biol. 24 (2005) 325-338
    • (2005) DNA Cell Biol. , vol.24 , pp. 325-338
    • Sims-Mourtada, J.C.1
  • 41
    • 15644373915 scopus 로고    scopus 로고
    • GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain
    • Snow B.E., et al. GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. J. Biol. Chem. 273 (1998) 17749-17755
    • (1998) J. Biol. Chem. , vol.273 , pp. 17749-17755
    • Snow, B.E.1
  • 45
    • 0037305038 scopus 로고    scopus 로고
    • Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system
    • Wieland T., and Mittmann C. Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system. Pharmacol. Ther. 97 (2003) 95-115
    • (2003) Pharmacol. Ther. , vol.97 , pp. 95-115
    • Wieland, T.1    Mittmann, C.2
  • 46
    • 12144286093 scopus 로고    scopus 로고
    • Support for RGS4 as a susceptibility gene for schizophrenia
    • Williams N.M., et al. Support for RGS4 as a susceptibility gene for schizophrenia. Biol. Psychiatry 55 (2004) 192-195
    • (2004) Biol. Psychiatry , vol.55 , pp. 192-195
    • Williams, N.M.1
  • 47
    • 0032567439 scopus 로고    scopus 로고
    • The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling
    • Zeng W., et al. The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling. J. Biol. Chem. 273 (1998) 34687-34690
    • (1998) J. Biol. Chem. , vol.273 , pp. 34687-34690
    • Zeng, W.1
  • 48
    • 0032706915 scopus 로고    scopus 로고
    • Structure, alternative splicing, and expression of the human RGS9 gene
    • Zhang K., et al. Structure, alternative splicing, and expression of the human RGS9 gene. Gene 240 (1999) 23-34
    • (1999) Gene , vol.240 , pp. 23-34
    • Zhang, K.1


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