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Volumn 10, Issue 5, 2008, Pages 1009-1012

Enzymatic synthesis of tumor-associated carbohydrate antigen globo-H hexasaccharide

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYL LACTOSE; 1-BENZYL-LACTOSE; FUCOSYLTRANSFERASE; GALACTOSYLTRANSFERASE; GLOBO H; GLOBO-H; LACTOSE; N ACETYLGALACTOSAMINYLTRANSFERASE; TUMOR ANTIGEN; UDP GALACTOSE LACTOSYLCERAMIDE ALPHA 1 4 GALACTOSYLTRANSFERASE; UDP-GALACTOSE-LACTOSYLCERAMIDE ALPHA 1-4-GALACTOSYLTRANSFERASE;

EID: 43549106881     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol703121h     Document Type: Article
Times cited : (35)

References (49)
  • 21
    • 0029959536 scopus 로고    scopus 로고
    • Park, T. K.; Kim, I. J.; Hu. S.; Biiodeau, M. T.; Randolph, J. T.; Kwon.O.; Danishefsky, S. J.J.Am. Chem. Soc. 1996, 118, 11488-11500.
    • (b) Park, T. K.; Kim, I. J.; Hu. S.; Biiodeau, M. T.; Randolph, J. T.; Kwon.O.; Danishefsky, S. J.J.Am. Chem. Soc. 1996, 118, 11488-11500.
  • 34
    • 0028997164 scopus 로고    scopus 로고
    • De Luca. C.; Lansing, M.; Martini, I.; Crescenzi, F.; Shen, G.-.J.; O'Regan, M.; Wong, C.-H.J. Am. Chem. Soc. 1995, 117, 5869-5870.
    • (e) De Luca. C.; Lansing, M.; Martini, I.; Crescenzi, F.; Shen, G.-.J.; O'Regan, M.; Wong, C.-H.J. Am. Chem. Soc. 1995, 117, 5869-5870.
  • 44
    • 58149191841 scopus 로고    scopus 로고
    • Spectroscopic data for Gb5-OBn: 1H NMR (500 MHz, D 2O, δ 7.47-7.38 (m, 5H, Ph, 4.91 (d, J, 11.7 Hz, 1H. PhCH2, 4.88 (d, J, 3.8 Hz. H-1‴, 4.74 (d, J, 11.8 Hz, 1H, PhCH2, 4.66 (d, J, 8.6 Hz, 1H, H-l, 4.52 (d, J, 8.1 Hz, 1H, H-1, 4.48 (d, J, 7.8 Hz. 1H, H-1, 4.42 (d, J, 7.7 Hz, 1H, H-1, 4.35 (t, J, 6.3 Hz, 1H, 4.22 (d, J, 1.7 Hz, 1H, 4.15 (d, J, 2.7 Hz, 1H, 4.03 (m, 1H, 4.01 (m, 1H, 3.97 (dd, J, 12.5, 1.6 Hz, 1H, 3.94 (dd, J, 10.1. 2.9 Hz, Hi, 3.91-3.85 (m. 4H, 3.82 (d, J, 4.4 Hz, 1H, 3.79 (d, J, 4.4 Hz. 1H, 3.78-3.69 (m, 6H, 3.68-3.65 (m, 3H, 3.64-3.61 (m, 2H, 3.60-3.53 (m, 4H, 3.50 (dd, J, 9.9, 7.9 Hz, 1H, 3.32 (t, J, 8.6 Hz. 1H, 1.99 (s, 3H, CH3CONH, l3C NMR 125 MHz, D2O, δ 175.2, 136.6, 128.8, 128.76, 128.5, 104.8, 103.3, 103.0. 101.0
    • 26Na ([M + Na]+) 982.3380, found 982.3405.
  • 47
    • 58149184288 scopus 로고    scopus 로고
    • Li, M, Liu, X.-W, Shao. J; Shen, J, Jia, Q, Yi, W, Song, J. K.;
    • Li, M.; Liu, X.-W.; Shao. J; Shen, J.; Jia, Q.; Yi, W.; Song, J. K.;
  • 49
    • 58149177749 scopus 로고    scopus 로고
    • Spectroscopic data for Globo-H-OBn: 1H NMR (500 MHz, D 2O):δ 7.46-7.38 (m, 5H, Ph, 5.20 (d, J, 4.1 Hz, 1H. H-1d‴, 4.91 (d, J =11.7 Hz, 1H, PhCH2, 4.86 (d, J, 3.9 Hz, 1H, H-1‴, 4.74 (d, J, 11.6 Hz, 1H. PhCH 2, 4.59 (d, J, 7.7 Hz, 1H, H-1, 4.53 (d,.J, 7.4 Hz. 1H. H-1, 4.51 (d, J, 6.7 Hz, 1H, H-1, 4.48 (d,.J, 7.7 Hz, 1H, H-1, 4.35 (t, J, 6.4 Hz, 1H, 4.22-4.18 (m, 2H, 4.07 (d, J, 2.1 Hz, 1H, 4.00 (d, J, 3.0 Hz, 1H, 3.98-3.94 (m, 3H, 3.91 (dd, J, 10.6, 2.8 Hz, 1H, 3.88-3.84 (m, 3H, 3.83-3.79 (m, 4H, 3.77 3.72 (m, 7H, 3.70-3.65 (m, 5H, 3.64-3.60 (m, 5H, 3.58-3.53 (m, 3H, 3.33 (t. J, 8.6 Hz. 1H, 2.01 (s, 3H. CH3CONH, 1.19 (d, J, 6.6 Hz, 3H, CH3 of fucose, 13C NMR-DEPT125 MHz, D 2O, δ 128.8, 128.77. 128.5, 104.0. 103.3, 102.1, 101.0, 100.5, 99.3
    • +) 1128.3959, found 1128.3981.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.