Insulin exocytosis in Goto-Kakizaki rat β-cells subjected to long-term glinide or sulfonylurea treatment

Biochemical Journal

Volumn 412, Issue 1, 2008, Pages 93-101

  Kawai, Junko ^a,b   Ohara Imaizumi, Mica ^a   Nakamichi, Yoko ^a   Okamura, Tadashi ^c   Akimoto, Yoshihiro ^a   Matsushima, Satsuki ^a   Aoyagi, Kyota ^a   Kawakami, Hayato ^a   Watanabe, Takashi ^a   Watada, Hirotaka ^b   Kawamori, Ryuzo ^b   Nagamatsu, Shinya ^a  

^a KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Exocytosis; Glinide; Insulin; Pancreatic cell; Sulfonylurea; Total internal reflection fluorescence (TIRF)

Indexed keywords

CELL PROLIFERATION; ELECTRON MICROSCOPY; LIVING SYSTEMS STUDIES; PROTEINS;

ETHYLMALEIMIDE; GLIBENCLAMIDE TREATMENT; TOTAL INTERNAL REFLECTION FLUORESCENCE (TIRF);

INSULIN;

GLIBENCLAMIDE; HUMAN INSULIN; INSULIN; NATEGLINIDE; SNARE PROTEIN; SULFONYLUREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL FUNCTION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; EXOCYTOSIS; GOTO KAKIZAKI RAT; IN VIVO STUDY; INSULIN RELEASE; MALE; MORPHOLOGY; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOOD GLUCOSE; CYCLOHEXANES; DIABETES MELLITUS, EXPERIMENTAL; EXOCYTOSIS; GLYBURIDE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; PHENYLALANINE; RATS; RATS, WISTAR; SNARE PROTEINS; SULFONYLUREA COMPOUNDS; TIME FACTORS;

RATTUS;

EID: 43549095481     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071282     Document Type: Article

References (43)

1. Kannel, W. B. and McGee, D. L. (1979) Diabetes and cardiovascular disease: the Framingham study. JAMA, J. Am. Med. Assoc. 241, 2035-2038
2. Stamler, J., Vaccaro, O., Neaton, J. D. and Wentworth, D. (1993) Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 16, 434-444
3. Efendic, S., Luft, R. and Wajngot, A. (1984) Aspects of the pathogenesis of type 2 diabetes. Endocr. Rev. 5, 395-410
4. Portha, B., Giroix, M. H., Serradas, P., Welsh, N., Hellerstrom, C., Sener, A. and Malaisse, W. J. (1988) Insulin production and glucose metabolism in isolated pancreatic islets of rats with NIDDM. Diabetes 37, 1226-1233
5. DeFronzo, R. A., Bonadonna, R. C. and Ferrannini, E. (1992) Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15, 318-368
6. Lebovitz, H. and Melander, A. (1997) Sulfonylureas: basic aspects and clinical uses. In International Textbook of Diabetes Mellitus, 2nd edn (Alberti, K. G. M. M., Zimmet, P. and DeFronzo, R. A., eds), Wiley, London 817-840
7. + channels and insulin secretion: their role in health and disease. Diabetologia 42, 903-919
8. Proks, P., Reimann, F., Green, N., Gribble, F. and Ashcroft, F. (2002) Sulfonylurea stimulation of insulin secretion. Diabetes 51 (Suppl. 3), S368-S376
9. Henquin, J. C. (1980) Tolbutamide stimulation and inhibition of insulin release: studies of the underlying ionic mechanisms in isolated rat islets. Diabetologia 18, 151-160
10. Malaisse, W. J. (2003) Pharmacology of the meglitinide analogs: new treatment options for type 2 diabetes mellitus. Treat. Endocrinol. 2, 401-414
11. ATP channels. Curr. Pharm. Des. 11, 2699-2716
12. Perfetti, R., Barnett, P. S., Mathur, R. and Egan, J. M. (1998) Novel therapeutic strategies for the treatment of type 2 diabetes. Diabetes Metab. Rev. 14, 207-225
13. Rendell, M. (2004) The role of sulphonylureas in the management of type 2 diabetes mellitus. Drugs 64, 1339-1358
14. Horton, E. S., Clinkingbeard, C., Gatlin, M., Foley, J., Mallows, S. and Shen, S. (2000) Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. Diabetes Care 23, 1660-1665
15. Nagamatsu, S., Ohara-Imaizumi, M., Nakamichi, Y., Kikuta, T. and Nishiwaki, C. (2006) Imaging docking and fusion of insulin granules induced by antidiabetes agents: sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules. Diabetes 55, 2819-2825
16. Rydberg, T., Jonsson, A., Karlsson, M. O. and Melander, A. (1997) Concentration-effect relations of glibenclamide and its active metabolites in man: modelling of pharmacokinetics and pharmacodynamics. Br. J. Clin. Pharmacol. 43, 373-381
17. Jonsson, A., Hallengren, B., Rydberg, T. and Melander, A. (2001) Effects and serum levels of glibenclamide and its active metabolites in patients with type 2 diabetes. Diabetes Obes. Metab. 3, 403-409
18. Ginier, P., Madan, S., Fajardo, F. and Levin, S. R. (1985) Once-daily use of glyburide. Am. J. Med. 79, 72-77
19. ATP channel activity and membrane-binding studies with nateglinide: a comparison with sulfonylureas and repaglinide. J. Pharmacol. Exp. Ther. 293, 444-452
20. Ciaraldi, T. P., Carter, L., Seipke, G., Mudaliar, S. and Henry, R. R. (2001) Effects of the long-acting insulin analog insulin glargine on cultured human skeletal muscle cells: comparisons to insulin and IGF-I. J. Clin. Endocrinol. Metab. 86, 5838-5847
21. Campbell, I. W. (2005) Nateglinide: current and future role in the treatment of patients with type 2 diabetes mellitus. Int. J. Clin. Pract. 59, 1218-1228
22. Nagamatsu, S., Nakamichi, Y., Yamamura, C., Matsushima, S., Watanabe, T., Ozawa, S., Furukawa, H. and Ishida, H. (1999) Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic β-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion. Diabetes 48, 2367-2373
23. Ohara-Imaizumi, M., Nishiwaki, C., Kikuta, T., Nagai, S., Nakamichi, Y. and Nagamatsu, S. (2004) TIRF imaging of docking and fusion of single insulin granule motion in primary rat pancreatic β-cells: different behaviour of granule motion between normal and Goto-Kakizaki diabetic rat β-cells. Biochem. J. 381, 13-18
24. Akimoto, Y., Kreppel, L. K., Hirano, H. and Hart, G. W. (1999) Localization of the O-linked N-acetylglucosamine transferase in rat pancreas. Diabetes 48, 2407-2413
25. Parsons, T. D., Coorssen, J. R., Horstmann, H. and Almers, W. (1995) Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells. Neuron 15, 1085-1096
26. Nagamatsu, S., Watanabe, T., Nakamichi, Y., Yamamura, C., Tsuzuki, K. and Matsushima, S. (1999) α-Soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic β-cells and functions in insulin but not γ-aminobutyric acid secretion. J. Biol. Chem. 274, 8053-8060
27. Ikenoue, T., Akiyoshi, M., Fujitani, S., Okazaki, K., Kondo, N. and Maki, T. (1997) Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D- phenylalanine (A-4166). Br. J. Pharmacol. 120, 137-145
28. Ohara-Imaizumi, M., Fujiwara, T., Nakamichi, Y., Okamura, T., Akimoto, Y., Kawai, J., Matsushima, S., Kawakami, H., Watanabe, T., Akagawa, K. and Nagamatsu, S. (2007) Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis. J. Cell Biol. 177, 695-705
29. Del Prato, S. and Tiengo, A. (2001) The importance of first-phase insulin secretion: implications for the therapy of type 2 diabetes mellitus. Diabetes Metab. Res. Rev. 17, 164-174
30. Firth, R. G., Bell, P. M., Marsh, H. M., Hansen, I. and Rizza, R. A. (1986) Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus: role of hepatic and extrahepatic tissues. J. Clin. Invest. 77, 1525-1532
31. Floyd, Jr, J. C., Funnell, M. M., Kazi, I. and Templeton, C. (1990) Feasibility of adjustment of insulin dose by insulin-requiring type II diabetic patients. Diabetes Care 13, 386-392
32. Steiner, K. E., Mouton, S. M., Bowles, C. R., Williams, P. E. and Cherrington, A. D. (1982) The relative importance of first- and second-phase insulin secretion in countering the action of glucagon on glucose turnover in the conscious dog. Diabetes 31, 964-972
33. Maedler, K., Sergeev, P., Ris, F., Oberholzer, J., Joller-Jemelka, H. I., Spinas, G. A., Kaiser, N., Halban, P. A. and Donath, M. Y. (2002) Glucose-induced β-cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J. Clin. Invest. 110, 851-860
34. Donath, M. Y., Ehses, J. A., Maedler, K., Schumann, D. M., Ellingsgaard, H., Eppler, E. and Reinecke, M. (2005) Mechanisms of β-cell death in type 2 diabetes. Diabetes 54, (Suppl. 2), S108-S113
35. Welsh, N., Cnop, M., Kharroubi, I., Bugliani, M., Lupi, R., Marchetti, P. and Eizirik, D. L. (2005) Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets? Diabetes 54, 3238-3244
36. Ohara-Imaizumi, M., Cardozo, A. K., Kikuta, T., Eizirik, D. L. and Nagamatsu, S. (2004) The cytokine interleukin-1β reduces the docking and fusion of insulin granules in pancreatic β-cells, preferentially decreasing the first phase of exocytosis. J. Biol. Chem. 279, 41271-41274
37. Laghmich, A., Ladriere, L., Malaisse-Lagae, F. and Malaisse, W. J. (1999) Long-term effects of glibenclamide and nateglinide upon pancreatic islet function in normal and diabetic rats. Pharmacol. Res. 40, 475-482
38. Ueki, K., Okada, T., Hu, J., Liew, C. W., Assmann, A., Dahlgren, G. M., Peters, J. L., Shackman, J. G., Zhang, M., Artner, I. et al. (2006) Total insulin and IGF-I resistance in pancreatic β-cells causes overt diabetes. Nat. Genet. 38, 583-588
39. Terauchi, Y., Takamoto, I., Kubota, N., Matsui, J., Suzuki, R., Komeda, K., Hara, A., Toyoda, Y., Miwa, I., Aizawa, S. et al. (2007) Glucokinase and IRS-2 are required for compensatory β-cell hyperplasia in response to high-fat diet-induced insulin resistance. J. Clin. Invest. 117, 246-257
40. Weir, G. C. and Bonner-Weir, S. (2007) A dominant role for glucose in β-cell compensation of insulin resistance. J. Clin. Invest. 117, 81-83
41. Ihara, Y., Toyokuni, S., Uchida, K., Odaka, H., Tanaka, T., Ikeda, H., Hiai, H., Seino, Y. and Yamada, Y. (1999) Hyperglycemia causes oxidative stress in pancreatic β-cells of GK rats, a model of type 2 diabetes. Diabetes 48, 927-932
42. Momose, K., Nunomiya, S., Nakata, M., Yada, T., Kikuchi, M. and Yashiro, T. (2006) Immunohistochemical and electron-microscopic observation of β-cells in pancreatic islets of spontaneously diabetic Goto-Kakizaki rats. Med. Mol. Morphol. 39, 146-153
43. Maedler, K., Carr, R. D., Bosco, D., Zuellig, R. A., Berney, T. and Donath, M. Y. (2005) Sulfonylurea induced β-cell apoptosis in cultured human islets. J. Clin. Endocrinol. Metab. 90, 501-506