Imaging docking and fusion of insulin granules induced by antidiabetes agents: Sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules

Diabetes

Volumn 55, Issue 10, 2006, Pages 2819-2825

  Nagamatsu, Shinya ^a   Ohara Imaizumi, Mica ^a   Nakamichi, Yoko ^a   Kikuta, Toshiteru ^a   Nishiwaki, Chiyono ^a  

^a KYORIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLIBENCLAMIDE; INSULIN; MITIGLINIDE; SULFONYLUREA RECEPTOR 1; ABC TRANSPORTER; ABCC8 PROTEIN, MOUSE; ANTIDIABETIC AGENT; INDOLE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUSION; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; EXOCYTOSIS; FLUORESCENCE MICROSCOPY; IMAGE ANALYSIS; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; ANIMAL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; IMAGE PROCESSING; MEMBRANE FUSION; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; RAT STRAIN; WISTAR RAT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DIABETES MELLITUS, EXPERIMENTAL; GLYBURIDE; HYPOGLYCEMIC AGENTS; IMAGE PROCESSING, COMPUTER-ASSISTED; INDOLES; INSULIN; INSULIN-SECRETING CELLS; MALE; MEMBRANE FUSION; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; RATS; RATS, MUTANT STRAINS; RATS, WISTAR;

EID: 33750894809     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0105     Document Type: Article

References (38)

1. Portha B, Giroix MH, Serradas P, Welsh N, Hellerstrom C, Sener A, Malaisse WJ: Insulin production and glucose metabolism in isolated pancreatic islets of rats with NIDDM. Diabetes 37:1226-1233, 1988
2. Ostenson CG, Khan A, Abdel-Halim SM, Guenifi A, Suņuki K, Goto Y, Efendic S: Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat. Diabetologia 36:3-8, 1993
3. Nagamatsu S, Nakamichi Y, Yamamura C, Matsushima S, Watanabe T, Ozawa S, Furukawa H, Ishida H: Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic β-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion. Diabetes 48:2367-2373, 1999
4. Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Kikuta T, Nagai S, Nagamatsu S: Correlation of syntaxin-1 and SNAP-25 clusters with docking and fusion of insulin granules analysed by total internal reflection fluorescence microscopy. Diabetologia 47:2200-2207, 2004
5. Henquin JC: Tolbutamide stimulation and inhibition of insulin release: studies of the underlying ionic mechanisms in isolated rat islets. Diabetologia 18:151-160, 1980
6. Lebovitz H, Melander A: Sulfonylureas: basic aspects and clinical uses. In International Textbook of Diabetes Mellitus. 2nd ed. Alberti KGMM, Zimmet P, DeFronzo RA, Eds. London, Wiley, 1997, p. 817-840
7. Ashcroft FM, Gribble FM: ATP-sensitive K+ channels and insulin secretion: their role in health and disease. Diabetologia 42:903-919, 1999
8. Proks P, Reimann F, Green N, Gribble F, Ashcroft FM: Sulfonylurea stimulation of insulin secretion. Diabetes 51 (Suppl. 3):S368-S376, 2002
9. ATP channels. Diabetes 47:1412-1418, 1998
10. Malaisse WJ: Pharmacology of the meglitinide analogs: new treatment option for type 2 diabetes mellitus. Treat Endocrinol 2:401-414, 2003
11. Bryan J, Crane A, Vila-Carriles WH, Bahenko AP, Aguilar-Bryan L: Insulin secretagogues, sulfonylurea receptors and KATP channels. Curr Pharm Des 11:2699-2716, 2005
12. Perfetti R, Barnett PS, Mathur R, Egan JM: Novel therapeutic strategies for the treatment of type 2 diabetes. Diabetes Metab Rev 14:207-225, 1998
13. Horton ES, Clinkingbeard C, Gatlin M, Foley J, Mallows S, Shen S: Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. Diabetes Care 23:1660-1665, 2000
14. Sunaga Y, Gonoi T, Shibasaki T, Ichikawa K, Kusama H, Yano H, Seino S: The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide. Eur J Pharmacol 431:119-125, 2001
15. ATP channels. Annu Rev Physiol 60:667-687, 1998
16. Gribble FM, Ashcroft FM: Differential sensitivity of beta-cell and extrapancreatic KATP channels to gliclazide. Diabetologia 42:845-848, 1999
17. Gribble FM, Tucker SJ, Ashcroft FM: The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation. J Physiology 504:35-45, 1997
18. +-channel opener sensitivity of KATP channels: functional coupling of Kir6.2 and SUR1 subunits. J Gen Physiol 114:203-213, 1999
19. Gribble FM, Reimann F: Sulphonylurea action revisited: the post-cloning era. Diabetologia 46:875-891, 2003
20. Hansen AM, Christensen IT, Hansen JB, Carr RD, Ashcroft FM, Wahl P: Differential interactions of nateglinide and repaglinide on the human β-cell sulphonylurea receptor 1. Diabetes 51:2789-2795, 2002
21. Chachin M, Yamada M, Fujita A, Matsuoka T, Matsushita K, Kurachi Y: Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamide moiety, specifically inhibits pancreatic beta cell-type KATP channels. J Pharmacol Exp Ther 304:1025-1032, 2003
22. Mogami H, Shibata H, Nobusawa R, Ohnota H, Satou F, Miyazaki J, Kojima I: Inhibition of ATP-sensitive K+ channel by a non-sulfonylurea compound KAD-1229 in a pancreatic beta-cell line, MIN 6 cell. Eur J Pharmacol 269:293-298, 1994
23. Ohara-Imaizumi M, Nakamichi Y, Tanaka T, Ishida H, Nagamatsu S: Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy: distinct behavior of granule motion in biphasic insulin release. J Biol Chem 277:3805-3808, 2002
24. Ohara-Imaizumi M, Nishiwaki C, Kikuta T, Nagai S, Nakamichi Y, Nagamatsu S: TIRF imaging of docking and fusion of single insulin granule motion in primary rat pancreatic beta-cells: different behaviour of granule motion between normal and Goto-Kakizaki diabetic rat beta-cells. Biochem J 381:13-18, 2004
25. Kasai K, Ohara-Imaizumi M, Takahashi N, Mizutani S, Zhao S, Kikuta T, Kasai H, Nagamatsu S, Gomi H, Izumi T: Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation. J Clin Invest 115:388-396, 2005
26. Ohara-Imaizumi M, Nakamichi Y, Tanaka T, Katsuta H, Ishida H, Nagamatsu S: Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy. Biochem J 363:73-80, 2002
27. Axelrod D: Cell surface contacts illuminated by total internal reflection fluorescence. J Cell Biol 89:141-145, 1981
28. ATP channel-independent regulation of insulin secretion. J Biol Chem 275:9270-9277, 2000
29. Kikuta T, Ohara-Imaizumi M, Nakazaki M, Nishiwaki C, Nakamichi Y, Tei C, Aguilar-Bryan L, Bryan J, Nagamatsu S: Docking and fusion of insulin secretory granules in SUR1 knock out mouse beta-cells observed by total internal reflection fluorescence microscopy. FEBS Lett 579:1602-1606, 2005
30. Marynissen G, Smets G, Kloppel G, Gerlache L, Mallaisse WJ: Internalization of glimepiride and glibenclamide in the pancreatic β cells. Acta Diabetol 29:113-114, 1992
31. Fuhlendorff J, Rorsman P, Kofod H, Brand CL, Rolin B, MacKay P, Shymko R, Carr RD: Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes. Diabetes 47:345-351, 1998
32. Ozanne SE, Guest PC, Hutton JC, Hales CN: Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells. Diabetologia 38:277-282, 1995
33. ATP channels of the endocrine pancreas. Diabetes 52:767-776, 2003
34. Renstrom E, Barg S, Thevenod F, Rorsman P: Sulfonylurea-mediated stimulation of insulin exocytosis via an ATP-sensitive K+ channel-independent action (Review). Diabetes 51 (Suppl. 1):S33-S36, 2002
35. Kamp F, Kizilbash N, Corkey BE, Berggren PO, Hamilton JA: Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism. Diabetes 52:2526-2531, 2003
36. Ivarsson R, Jing X, Waselle L, Regazzi R, Renstrom E: Myosin 5a controls insulin granule recruitment during late-phase secretion. Traffic 6:1027-1035, 2005
37. Barg S, Huang P, Eliasson L, Nelson DJ, Obermuller S, Rorsman P, Thevenod F, Renstrom E: Priming of insulin granules for exocytosis by granular Cl- uptake and acidification. J Cell Sci 114:2145-2154, 2001
38. Thevenod F: Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins. Am J Physiol Cell Physiol 283:C651-C672, 2002