The AMPA modulator S 18986 improves declarative and working memory performances in aged mice

Behavioural Pharmacology

Volumn 19, Issue 3, 2008, Pages 235-244

  Marighetto, Aline ^a   Valerio, Stephane ^a   Jaffard, Robert ^a   Mormede, Cecile ^a   Muñoz, Carmen ^b   Bernard, Katy ^b   Morain, Philippe ^b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Ageing; AMPA modulator; Mnemonic flexibility; Mouse; Short term retention

Indexed keywords

2,3 DIHYDRO 3,4 CYCLOPENTANO 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BENZOTHIADIAZINE DERIVATIVE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DECLARATIVE MEMORY; DRUG DOSAGE FORM COMPARISON; DRUG MEGADOSE; LONG TERM MEMORY; LOW DRUG DOSE; MALE; MAZE TEST; MOUSE; NONHUMAN; SHORT TERM MEMORY; TASK PERFORMANCE; WORKING MEMORY;

AGING; ANIMALS; BEHAVIOR, ANIMAL; BENZOTHIADIAZINES; DISCRIMINATION LEARNING; DISEASE MODELS, ANIMAL; MALE; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; RECEPTORS, AMPA;

EID: 43449138511     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3282feb0c1     Document Type: Article

References (55)

1. Baddeley AD, Hitch GJ (1974). Working memory. In: Bower GH, ed. The psychology of learning and motivation: advances in research in theory. Vol. 8. New York: Academic Press; pp. 47-89.
2. Barnes CA, Rao G, Orr G (2000). Age-related decrease in the Schaffer collateral-evoked EPSP in awake, freely behaving rats. Neural Plast 7:167-178.
3. Beracochea D, Philippin JN, Meunier S, Morain P, Bernard K (2007). Improvement of episodic contextual memory by S 18986 in middle-aged mice: comparison with donepezil. Psychopharmacology 193:63-73.
4. Bernstein D, Olton DS, Ingram DK, Waller SB, Reynolds MA, London ED (1985). Radial maze performance in young and aged mice: neurochemical correlates. Pharmacol Biochem Behav 22:301-307.
5. Bertaina-Anglade V, La Rochelle CD, Munoz C, Morain P, Bernard K (2007). Comparison of single vs. multiple administrations of the AMPA receptors modulator S 18986 in the object recognition task in rats. Fundam Clin Pharmacol 21:349-354.
6. Bourasset F, Bernard K, Munoz C, Genissel P, Scherrmann JM (2005). Aug. Neuropharmacokinetics of a new a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) modulator, S 18986 [(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4- benzothiadiazine-1,1-dioxide], in the rat. Drug Metab Dispos 33:1137-1143.
7. Bowles RP, Salthouse TA (2003). Assessing the age-related effects of proactive interference on working memory tasks using the Rasch model. Psychol Aging 18:608-615.
8. Buccafusco JJ, Weiser T, Winter K, Klinder K, Terry AV Jr (2004). The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology 46:10-22.
9. Burke SN, Barnes CA (2006). Neural plasticity in the ageing brain. Nat Rev Neurosci 1:30-40. Review.
10. Chappell AS, Gonzales C, Williams J, Witte MM, Mohs RC, Sperling R (2007). AMPA potentiator treatment of cognitive deficits in Alzheimer disease. Neurology 68:1008-1012.
11. Cohen NJ (1984). Preserved learning capacity in amnesia: evidence for multiple memory systems. In: Squire LRBN, ed. Neuropsychology of memory. New York: Guilford press; pp. 83-103.
12. Craik FI, Rabinowitz JC (1985). The effects of presentation rate and encoding task on age-related memory deficits. J Gerontol 40:309-315.
13. Daigneault S, Braun CM (1993). Working memory and the self-ordered pointing task: further evidence of early prefrontal decline in normal aging. J Clin Exp Neuropsychol 15:881-895.
14. Derkach VA, Oh MC, Guire ES, Soderling TR (2007). Regulatory mechanisms of AMPA receptors in synaptic plasticity. Nat Rev Neurosci 8:101-113.
15. Desos P, Serkiz B, Morain P, Lepagnol J, Cordi A (1996). Enantioselective synthesis of a pyrrolo-benzothiadiazine derivate S 18986-1, a new AMPA receptor positive modulator. Bioorg Med Chem Lett 6:3003-3008.
16. Dunnett SB, Martel FL, Iversen SD (1990). Proactive interference effects on short-term memory in rats: II. effects in young and aged rats. Behav Neurosci 104:666-670.
17. Eichenbaum H (2004). Hippocampus: cognitive processes and neural representations that underlie declarative memory. Neuron 44:109-120. Review.
18. Etchamendy N, Enderkin V, Marighetto A, Vouimba RM, Pallet V, Jaffard R, Higueret P (2001). Alleviation of a selective age-related relational memory deficit in mice by pharmacologically induced normalization of brain retinoid signaling. J Neurosci 21:6423-6429.
19. Etchamendy N, Desmedt A, Cortes-Torrea C, Marighetto A, Jaffard R (2003). Hippocampal lesions and discrimination performance of mice in the radial maze: sparing or impairment depending on the representational demands of the task. Hippocampus 13:197-211.
20. Granger R, Staubli U, Davis M, Perez Y, Nilsson L, Rogers GA, Lynch G (1993). A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task. Synapse 15:326-329.
21. Lauterborn JC, Truong GS, Baudry M, Bi X, Lynch G, Gall CM (2003). Chronic elevation of brain-derived neurotrophic factor by ampakines. J Pharmacol Exp Ther 307:297-305.
22. Lebrun C, Pilliere E, Lestage P (2000). Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats. Eur J Pharmacol 401:205-212.
23. Lee H-K, Takamiya K, Han J-S, Man H, Kim C-H, Rumbaugh G, et al. (2003). Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell 112:631-643.
24. Lepagnol J, Lebrun C, Pilliere E, Thomas JY, Desos P, Cordi A, Lestage P (1997). Neuroexcitatory and cognition enhancing effect of S 18986, a positive allosteric modulator of glutamate AMPA receptor. 27th Annual Meeting of the Neuroscience Society, New Orleans. American Soc Neuroscience 23:1841.
25. Lockhart B, Iop F, Closier M, Lestage P (2000). (S)-2,3-dihydro-[3,4] cyclopentano-1,2,4-benzothiadiazine-1,1 dioxide: (S 18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H] noradrenaline release form rat hippocampal and frontal cortex slices. Eur J Pharm 401:145-153.
26. Lockhart BP, Rodriguez M, Mourlevat S, Peron P, Catesson S, Villain N, et al. (2007). S 18986: a positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures. Eur J Pharmacol 561:23-31.
27. Luebke JI, Chang YM, Moore TL, Rosene DL (2004). Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex. Neuroscience 125:277-288.
28. Lynch G (2002). Memory enhancement: the search for mechanism-based drugs. Nat Neurosci 5 (Suppl):1035-1038.
29. Lynch G (2004). AMPA receptor modulators as cognitive enhancers. Curr Opin Pharmacol 4:4-11.
30. Lynch G (2006). Glutamate-based therapeutic approaches: ampakines. Curr Opin Pharmacol 6:82-88.
31. Lynch G, Gall CM (2006). Ampakines and the threefold path to cognitive enhancement. Trends Neurosci 29:554-562.
32. Lynch G, Granger R, Ambros-Ingerson J, Davis CM, Kessler M, Schehr R (1997). Evidence that a positive modulator of AMPA-type glutamate receptors improves delayed recall in aged humans. Exp Neurol 145:89-92.
33. Marighetto A, Etchamendy N, Touzani K, Torrea CC, Yee BK, Rawlins JN, Jaffard R (1999). Knowing which and knowing what: a potential mouse model for age-related human declarative memory decline. Eur J Neurosci 11:3312-3322.
34. Marighetto A, Touzani K, Etchamendy N, Torrea CC, De Nanteuil G, Guez D, et al. (2000). Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor. Learn Mem 7:159-169.
35. Marighetto A, Valerio S, Desmedt A, Philippin JN, Trocmé-Thibierge C, Morain P (2008). Comparative effects of the α7 nicotinic partial agonist, S 24795 and the cholinesterase inhibitor, donepezil against aging-related deficits in declarative and working memory in mice. Psychopharmacology (In press).
36. Marighetto A, Valerio S, Philippin JN, Bertaina-Anglade V, Drieu La Rochelle C, Jaffard R, Morain P (2008). Comparative effects of the dopaminergic agonists piribedil and bromocriptine in three different memory paradigms in rodents. J Psychopharmacol (In press).
37. Marenco S, Weinberger DR (2006). Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders. CNS Drugs 20:173-185.
38. McCabe DP, Robertson CL, Smith AD (2005). Age differences in stroop interference in working memory. J Clin Exp Neuropsychol 27:633-644.
39. Mingaud F, Le Moine C, Etchamendy N, Mormède C, Jaffard R, Marighetto A (2007). The hippocampus plays a critical role at encoding discontiguous events for subsequent declarative memory expression in mice. Hippocampus 17:264-270.
40. Mingaud F, Mormede C, Etchamendy N, Mons N, Niedergang B, Wietrzych M, et al. (2008). Retinoid hyposignaling contributes to aging-related decline in hippocampal function in short-term/working memory organization and long-term declarative memory encoding in mice. J Neurosci 28:279-291.
41. Morrow JA, Maclean JKF, Jamieson C (2006). Recent advances in positive allosteric modulators of the AMPA receptor. Curr Opin Drug Discov Devel 9:571-579.
42. Moss MB, Rosene DL, Peters A (1988). Effects of aging on visual recognition memory in the rhesus monkey. Neurobiol Aging 9:495-502.
43. Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, et al. (2003). LY503430, a novel α-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease. J Pharmacol Exp Ther 306:752-762.
44. O'Neill MJ, Bleakman D, Zimmerman DM, Nisenbaum ES (2004). AMPA receptor potentiators for the treatment of CNS disorders. Curr Drug Targets CNS Neurol Disord 3:181-194.
45. Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton AA, Sacktor TC (2006). Storage of spatial information by the maintenance mechanism of LTP. Science 313:1141-1144.
46. Repovs G, Baddeley A (2006). The multi-component model of working memory: explorations in experimental cognitive psychology. Neuroscience 139:5-21.
47. Robbins TW, Murphy ER (2006). Behavioural pharmacology: 40 + years of progress, with a focus on glutamate receptors and cognition. Trends Pharmacol Sci 27:141-148.
48. Rosi S, Giovannini MG, Lestage PJ, Munoz C, Corte LD, Pepeu G (2004). S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat. Neurosci Lett 361:120-123.
49. Smith AD (1979). The interaction between age and list length in free recall. J Gerontol 4:381-387.
50. Touzani K, Marighetto A, Jaffard R (2003). Fos imaging reveals ageing-related changes in hippocampal response to radial maze discrimination testing in mice. Eur J Neurosci 17:628-640.
51. Van Dam D, Abramowski D, Staufenbiel M, De Deyn PP (2005). Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model. Psychopharmacology 180:177-190.
52. Wallenstein GV, Eichenbaum H, Hasselmo ME (1999). The hippocampus as an associator of discontiguous events. Trends Neurosci 21:317-323.
53. Wezenberg E, Verkes RJ, Ruigt Ge SF, Hulstijn W, Sabbe B (2007). Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology 32:1272-1283.
54. Whitlock JR, Heynen AJ, Shuler MG, Bear MF (2006). Learning induces long-term potentiation in the hippocampus. Science 313:1093-1097.
55. Winocur G (1984). The effects of retroactive and proactive interference on learning and memory in old and young rats. Dev Psychobiol 17:537-545.