β-Glucans in promoting health: Prevention against mutation and cancer

Mutation Research - Reviews in Mutation Research

Volumn 658, Issue 3, 2008, Pages 154-161

  Mantovani, Mário S ^a   Bellini, Marilanda F ^b   Angeli, José Pedro F ^a   Oliveira, Rodrigo J ^a   Silva, Ariane F ^a   Ribeiro, Lúcia R ^b  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Glucans; Anticarcinogenic; Antimutagenesis; Biological activities; Chemoprevention

Indexed keywords

BETA GLUCAN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOCHROME P450; DOXORUBICIN; FREE RADICAL; HELIX LOOP HELIX PROTEIN; ISOENZYME; KRESTIN; LENTINAN; METHOTREXATE; SCHIZOPHYLLAN;

AGARICUS BLAZEI; ANTICOAGULATION; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; BARLEY; BIOTRANSFORMATION; CANCER PREVENTION; CELLULAR IMMUNITY; CEREAL; CHEMOPROPHYLAXIS; CHO CELL; DIETARY INTAKE; ENZYME ACTIVITY; HEALTH PROMOTION; HUMAN; HUMORAL IMMUNITY; IMMUNOMODULATION; LENTINUS EDODES; MOLECULAR WEIGHT; MUSHROOM; MUTAGENESIS; NONHUMAN; NUTRITIONAL HEALTH; OAT; PLEUROTUS; POLYMERIZATION; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; SCHIZOPHYLLUM COMMUNE; STRUCTURE ACTIVITY RELATION; YEAST;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMUTAGENIC AGENTS; ANTINEOPLASTIC AGENTS; BETA-GLUCANS; CYTOPROTECTION; HEALTH PROMOTION; HUMANS; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS;

AVENA; BACTERIA (MICROORGANISMS); BASIDIOMYCOTA; HORDEUM;

EID: 43449138203     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrrev.2007.07.002     Document Type: Review

References (54)

1. Cisneros R.L., Gibson F.C., and Tzianabos A.O. Passive transfer of poly-(1-6)-β-glucotriosyl-(1-3)-β-glucopyranose glucana protection against lethal infection in an animal model of intra-abdominal sepsis. Infect. Immun. 64 (1996) 2201-2205
2. Zimmerman J.W., Lindermuth J., Fish P.A., Palace G.P., Stevenson T.T., and DeMong D.E. A novel carbohydrate-glycosphingolipid interaction between a β-(1-3)-glucan immunomodulador, PGG-glucan, and lactosylceramide of human leukocytes. J. Biol. Chem. 273 (1998) 22014-22020
3. Turnbull J.L., Patchen M.L., and Scadden D.T. The polysaccharide, PGG-glucan, enhances human myelopoiesis by direct action independent of and additive to early-acting cytokines. Acta Haematol. 102 (1999) 66-71
4. Masihi K.N. Immunomodulators in infectious diseases panoply of possibilities. Int. J. Immunopharmacol. 22 (2000) 1083-1091
5. Zekovic D.B., Kwiatkowski S., Vrvic M.M., Jakovljevic D., and Moran C.A. Natural modified (1 → 3)-β-glucans in health promotion and disease alleviation. Crit. Rev. Biotechnol. 25 (2005) 205-230
6. Di Luzio N.R., Williams D.L., Mcnamee R.B., Edwards B.F., and Kitahama A. Comparative tumor-inhibitory and anti-bacterial activity of soluble and particulate glucana. Int. J. Cancer 24 (1979) 773-779
7. Sandula J., Machová E., and Vhribalová V. Mitogenic activity of particulate yeast β-(1 → 3)-d-glucan and its water-soluble derivatives. Int. J. Biol. Macromol. 17 (1995) 323-326
8. Tohamy A.A., El-Gohr A.A., El-Nahas S.M., and Noshy M.M. β-Glucan inhibits the genotoxicity of cyclophosphamide, adramycin and cisplatin. Mutat. Res. 541 (2003) 45-53
9. Keegstra K., and Walton J. β-Glucans-brewer's bane, dietician' delight. Science 311 (2006) 1872-1873
10. Ooi V.E.C., and Liu F. Immunomodulation and anti-cancer activity of polysaccharide-proteins complexes. Curr. Med. Chem. 7 (2000) 715-729
11. Chang Y.J., Lee S., Yoo M.A., and Lee H.G. Structural and biological characterization of sulfated-derivatized oat β-glucan. J. Agric. Food Chem. 54 (2006) 3815-3818
12. Kawagishi H., Inagaki R., Kanao T., and Mizuno T. Fraction and antitumoral activity of the water-insoluble reside of Agaricus blazei fruiting bodies. Carbohydr. Res. 186 (1989) 267-273
13. Ohno N., Furukawa M., Miura N.N., Adachi Y., Motoi M., and Yadomae T. Antitumoral β-glucan from cultured fruit body of A. blazei. Biol. Pharm. Bull. 24 (2001) 820-828
14. Mizuno T., Hagiwara T., Nakamura T., Ito H., Shimura K., Sumiya T., and Asakura A. Antitumoral activity and some properties of water-soluble polysaccharides from "Himematsutake", the fruiting body of Agaricus blazei Murill. Agric. Biol. Chem. 54 (1990) 2889-2896
15. Camelini C.M., Maraschin M., Mendonça M.M., Zucco C., Ferreira A.G., and Tavares L.A. Structural characterization of β-glucans of Agaricus brasiliensis in different stages of fruiting body maturity and their use in nutraceutical products. Biotechnol. Lett. 27 (2005) 1295-1299
16. Shin M.S., Lee S., Lee K.Y., and Lee H.G. Structural and biological characterization of aminated-derivatized oat β-glucan. J. Agric. Food Chem. 53 (2005) 5554-5558
17. Zhang M., Zhang L., Wang Y., and Cheung P.C. Chain conformation of sulfated derivatives of beta-glucan from sclerotia of Pleurotus tuber-regium. Carbohydr. Res. 338 (2003) 2863-2870
18. Wang Y., Zhang L., Li Y., Hou X., and Zeng F. Correlation of structure to antitumoral activities of betaglucan from Poria cocos sclerotium. Carbohydr. Res. 339 (2004) 2567-2574
19. Alban S., and Franz G. Anticoagulant activities of beta-1,3-glucansulfates in dependence on their molecular weight. Pure Appl. Chem. 66 (1994) 2403-2406
20. Alban S., Jeske W., Welzen D., Granz G., and Fareed J. Anticoagulant and antithrombotic activity actions of a semisynthetic beta-1,3-glucan sulfate. Thromb. Res. 78 (1995) 201-210
21. Martinichen-Herrero J.C., Carboneroa E.R., Gorina P.A.J., and Iacomini M. Anticoagulant and antithrombotic activity of a sulfate obtained from a glucan component of the lichen Parmotrema mantiqueirense Hale. Carbohydr. Polym. 60 (2005) 7-13
22. Miura N.N., Adachi Y., Yadomae T., Tamura H., Tanaka S., and Ohno N. Structure and biological activities of β-glucans from yeast and mycelial forms of Candida albicans. Microbiol. Immunol. 47 (2003) 173-182
23. Brown G.D., and Gordon S. Fungal β-glucans and mammalian immunity. Immunity 19 (2003) 311-315
24. Reynolds J.A., Kastello M.D., Harrigton D.G., Crabs C.L., Peters C.J., Jemski J.V., Scott G.H., and Di Luzio N.R. Glucan-induced enhancement of host resistance to selected infectious diseases. Infect. Immun. 30 (1980) 51-57
25. Meira D.A., Pereira P.C.M., Marcondes-Machado J., Barravieira R.P., Pellegrino J.R.J., Rezkallah-Iwasso M.T., Peraçoli M.T.S., Castilho L.M., Thomzaini I., Silva C.L., Foss N.T., and Curi P.R. The use of glucan as immunostimulant in treatment of paracoccidiomycosis. Am. J. Trop. Med. Hyg. 55 (1996) 496-503
26. Yun C.H., Estrada A., Kessel A.V., Gajadhar A., Redmond M., and Laearveld B. Immunomodulatory effects of a oat-β-glucan administered intragastrically or parentally on mice infected with Eimeria verminoformis. Microbiol. Immunol. 42 (1998) 457-465
27. Soltýs J., Borosková Z., Dubinski P., Tomasovicová O., Auer H., and Aspock H. Effect of glucan immunomodulator on the immuno response and larval burdens in mice experimental toxocaris. Appl. Parasitol. 37 (1996) 161-167
28. Bohn J.A., and Miller J.N. (1 → 3)-β-d-Glucans as biological response modifiers: a review of structure-functional activity relationships. Carbohydr. Polym. 28 (1995) 3-14
29. Falch B.H., Espevik T., Ryan L., and Stokke B.T. The cytokine stimulating activity of (1 → 3)-β-d-glucans is dependent on the triple helix conformation. Carbohydr. Res. 329 (2000) 587-596
30. Tokunaka K., Ohno N., Adachi Y., Tanaka S., Tamura H., and Yadomae T. Immunopharmacological and immunotoxicological activities of a water soluble (1 → 3)-β-glucan, CSBG from Candida albicans. Int. J. Immunopharmacol. 22 (2000) 383-394
31. Kubala L., Ruzickova J., Nickova K., Sandula J., Ciz M., and Lojek A. The effect of (1 → 3)-β-d-glucans, carboxymethylglucan and schizophyllan on human leukocytes in vitro. Carbohydr. Res. 338 (2003) 2835-2840
32. Luhm J., Langenkamp U., Hensel J., Frohn C., Brand J.M., Hennig H., Rink L., Koritke P., Wittkopf N., Williams D.L., and Mueller A. β-(1 → 3)-d-Glucan modulates DNA binding of nuclear factors kB, AT and IL-6 leading to an anti-inflammatory shift of the IL-Iβ/IL-1 receptor antagonist ratio. BMC Immunol. 7 (2006) 1-15
33. Chae B.J., Lohakare J.D., Moon W.K., Lee S.L., Park Y.H., and Hahn T.W. Effects of supplementation of β-glucan on the growth performance and immunity in broilers. Res. Vet. Sci. 80 (2006) 291-298
34. Grinde B., Hetland G., and Johson E. Effects on gene expression and viral load of a medicinal extract from Agaricus blazei in patients with chronic hepatitis C infection. Int. Immunopharmacol. 6 (2006) 1311-1314
35. Kuo Y.C., Huang Y.L., Chen C.C., Lin Y.S., Chuang K.A., and Tsai W.J. Cell cycle progression and cytokine gene expression of human peripheral blood mononuclear cells modulated by Agaricus blazei. J. Lab. Clin. Med. 140 (2002) 176-187
36. Bernardshaw S., Hetland G., Grinde B., and Johnson E. An extract of the mushroom Agaricus blazei Murill protects against lethal septicemia in a mouse model for fecal priotonitis. Shock 24 (2006) 319-320
37. Liang J., Melican D., Cafro L., Palace G., Fisette L., Armstrong R., and Patchen M.L. Enhanced clearance of a multiple antibiotic resistant Staphylococcus aureus in rats tested with PGG-glucan is associated with increased leukocyte counts and increased neutophil oxidative burst activity. Int. J. Immunopharmacol. 20 (1998) 595-614
38. Kaiser A.B., and Kernodle D. Synergism between poly-(1 → 6)-β-d-glucopyranose glucana and cefazolin in prophylaxis of staphylococcal wound infection in guinea pig model. Antimicrobiol. Agents Chemother. 42 (1998) 2449-2451
39. Alban S., and Franz G. Partial synthetic glucan sulfates as potential new antithrombotics: a review. Biomacromolecules 2 (2001) 354-361
40. Colliec- Jouault S., Chevolot L., Helley D., Ratiskol J., Bros A., Sinquin C., Roger O., and Fischer A.M. Characterization chemical modifications and in vivo anticoagulant properties of exopolysaccharide produced by Alteromonas infernos. Biochim. Biophys. Acta 1528 (2001) 141-151
41. Oliveira R.J., Ribeiro L.R., Silva A.F., Matuo R., and Mantovani M.S. Evaluation of antimutagenic activity and mechanisms of action of β-glucan from barley, in CHO-K1 and HTC cell lines using the micronucleus test. Toxicol. In Vitro 20 (2006) 1225-1233
42. Angeli J.P.F., Ribeiro L.R., Gonzaga M.L.C., Soares S.A., Ricardo M.P.S.N., Tsuboy M.S., Stidl R., Knasmuller S., Linhares R.E., and Mantovani M.S. Protective effects of β-glucan extracted from Agaricus brasiliensis against chemically induced DNA damage in human lymphocytes. Cell Biol. Toxicol. 22 (2006) 285-291
43. Oliveira R.J., Matuo R., Silva A.F., Matiazi H.J., Mantovani M.S., and Ribeiro L.R. Protective effect of β-glucan extracted from Saccharomyces cerevisiae, against DNA damage and cytotoxicity in wild-type (K1) and repair-deficient (xrs5) CHO cells. Toxicol. In Vitro 21 (2006) 41-52
44. Krizkova L., Zitnanova I., Mislovicova D., Masarova J., Sasinkova V., Durackova Z., and Krajcovica J. Antioxidant and antimutagenic activity of mannan neoglycoconjugates: mannan-human serum albumin and mannan-penicillin G acylase. Mutat. Res. 606 (2006) 72-79
45. Davegowda G., Raju M.V.L.N., and Swamy H.V.L.N. Mycotoxins: novel solutions for their counteraction. Feedstuffs 70 (1998) 12-15
46. Chorvatovicová D. Suppressing effects of glucan on micromuceli induced by Co60 in mice. Stranhlenther Onkol. 167 (1991) 612-614
47. Slamenová D., Lábaj J., Krizková L., Kogan G., Sandula J., Bresgen N., and Eckl P. Protective effects of fungal β-d-glucan derivatives against oxidative DNA lesions in V79 hamster lung cells. Cancer Lett. 198 (2003) 153-160
48. Angeli J.P.F., Ribeiro L.R., Bellini M.F., and Mantovani M.S. Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells. Hum. Exp. Toxicol. 25 (2006) 319-324
49. Hashimoto T., Nonaka Y., and Minato K. Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice. Biosci. Biotechnol. Biochem. 344 (2002) 610-1614
50. Okamoto T., Kodoi R., and Nonaka Y. Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver. Biofactors 21 (2004) 407-409
51. Kiho T., Matsushita M., Usui S., and Ukai S. Biological activities of (1 → 3)-β-d-glucan with reducing glucose side chains. Biosci. Biotechnol. Biochem. 62 (1998) 570-572
52. Zhang L., Xuelian L., Xu X., and Zeng F. Correlation between antitumoral activity, molecular weight, and conformation of lentinan. Carbohydr. Res. 340 (2005) 1515-1521
53. Sener G., Eksioglu-Demiralp E., Çetiner M., Ercan F., and Yegen B.C. β-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects. Eur. J. Pharmacol. 542 (2006) 170-178
54. Davidson M.H., Dugan L.D., Burns J.H., Bova J., Story K., and Drennan K.B. The hypocholesterolemic effects of beta-glucan in oatmeal and oat bran. A dose-controlled study. JAMA 265 (1991) 1079-1080