메뉴 건너뛰기




Volumn 104, Issue 2, 2008, Pages 435-443

The role of protein translocation in the regulation of glycogen metabolism

Author keywords

Glucokinase; GLUT4; Glycogen synthase; Hexokinase; Insulin; Phosphorylase

Indexed keywords

GLUCOKINASE; GLYCOGEN SYNTHASE; HEXOKINASE; PHOSPHORYLASE;

EID: 43449123638     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21634     Document Type: Review
Times cited : (17)

References (65)
  • 1
    • 0029093298 scopus 로고
    • The regulatory protein of glucokinase binds to the hepatocyte matrix, but, unlike glucokinase, does not translocate during substrate stimulation
    • Agius L, Peak M, Van Schaftingen E. 1995. The regulatory protein of glucokinase binds to the hepatocyte matrix, but, unlike glucokinase, does not translocate during substrate stimulation. Biochem J 309(Pt 3):711-713.
    • (1995) Biochem J , vol.309 , Issue.PART 3 , pp. 711-713
    • Agius, L.1    Peak, M.2    Van Schaftingen, E.3
  • 2
    • 0029851722 scopus 로고    scopus 로고
    • Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis
    • Agius L, Peak M, Newgard CB, Gomez-Foix AM, Guinovart JJ. 1996. Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis. J Biol Chem 271:30479-30486.
    • (1996) J Biol Chem , vol.271 , pp. 30479-30486
    • Agius, L.1    Peak, M.2    Newgard, C.B.3    Gomez-Foix, A.M.4    Guinovart, J.J.5
  • 3
    • 0038660083 scopus 로고    scopus 로고
    • Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase
    • Aiston S, Andersen B, Agius L. 2003. Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase. Diabetes 52:1333-1339.
    • (2003) Diabetes , vol.52 , pp. 1333-1339
    • Aiston, S.1    Andersen, B.2    Agius, L.3
  • 4
    • 1642452990 scopus 로고    scopus 로고
    • Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose
    • Aiston S, Green A, Mukhtar M, Agius L. 2004. Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose. Biochem J 377:195-204.
    • (2004) Biochem J , vol.377 , pp. 195-204
    • Aiston, S.1    Green, A.2    Mukhtar, M.3    Agius, L.4
  • 5
    • 33845536286 scopus 로고    scopus 로고
    • Glucokinase regulatory network in pancreatic {beta}-cells and liver
    • Baltrusch S, Tiedge M. 2006. Glucokinase regulatory network in pancreatic {beta}-cells and liver. Diabetes 55 (Suppl 2):S55-S64.
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Baltrusch, S.1    Tiedge, M.2
  • 6
    • 0037262963 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells
    • Boustead JN, Stadelmaier BT, Eeds AM, Wiebe PO, Svitek CA, Oeser JK, O'Brien RM. 2003. Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells. Biochem J 369:17-22.
    • (2003) Biochem J , vol.369 , pp. 17-22
    • Boustead, J.N.1    Stadelmaier, B.T.2    Eeds, A.M.3    Wiebe, P.O.4    Svitek, C.A.5    Oeser, J.K.6    O'Brien, R.M.7
  • 7
    • 0030953106 scopus 로고    scopus 로고
    • Glucokinase regulatory protein may interact with glucokinase in the hepatocyte nucleus
    • Brown KS, Kalinowski SS, Megill JR, Durham SK, Mookhtiar KA. 1997. Glucokinase regulatory protein may interact with glucokinase in the hepatocyte nucleus. Diabetes 46:179-186.
    • (1997) Diabetes , vol.46 , pp. 179-186
    • Brown, K.S.1    Kalinowski, S.S.2    Megill, J.R.3    Durham, S.K.4    Mookhtiar, K.A.5
  • 9
    • 0026667618 scopus 로고
    • Sequence of insulin effects on cytoskeletal and cytosolic phosphofructokinase, mitochondrial hexokinase, glucose 1,6-bisphosphate and fructose 2,6-bisphosphate levels, and the antagonistic action of calmodulin inhibitors, in diaphragm muscle
    • Chen-Zion M, Bassukevitz Y, Beitner R. 1992. Sequence of insulin effects on cytoskeletal and cytosolic phosphofructokinase, mitochondrial hexokinase, glucose 1,6-bisphosphate and fructose 2,6-bisphosphate levels, and the antagonistic action of calmodulin inhibitors, in diaphragm muscle. Int J Biochem 24:1661-1667.
    • (1992) Int J Biochem , vol.24 , pp. 1661-1667
    • Chen-Zion, M.1    Bassukevitz, Y.2    Beitner, R.3
  • 12
    • 0018672517 scopus 로고
    • Kinetics of 3-O-methyl-D- glucose transport in isolated rat hepatocytes
    • Craik JD, Elliott KR. 1979. Kinetics of 3-O-methyl-D- glucose transport in isolated rat hepatocytes. Biochem J 182:503-508.
    • (1979) Biochem J , vol.182 , pp. 503-508
    • Craik, J.D.1    Elliott, K.R.2
  • 13
    • 0033525087 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase translocates onto liver endoplasmic reticulum and may account for the inhibition of glucose-6-phosphatase during refeeding
    • Daniele N, Rajas F, Payrastre B, Mauco G, Zitoun C, Mithieux G. 1999. Phosphatidylinositol 3-kinase translocates onto liver endoplasmic reticulum and may account for the inhibition of glucose-6-phosphatase during refeeding. J Biol Chem 274:3597-3601.
    • (1999) J Biol Chem , vol.274 , pp. 3597-3601
    • Daniele, N.1    Rajas, F.2    Payrastre, B.3    Mauco, G.4    Zitoun, C.5    Mithieux, G.6
  • 14
    • 0025082923 scopus 로고
    • Fructose 1-phosphate and the regulation of glucokinase activity in isolated hepatocytes
    • Davies DR, Detheux M, Van Schaftingen E. 1990. Fructose 1-phosphate and the regulation of glucokinase activity in isolated hepatocytes. Eur J Biochem 192:283-289.
    • (1990) Eur J Biochem , vol.192 , pp. 283-289
    • Davies, D.R.1    Detheux, M.2    Van Schaftingen, E.3
  • 15
    • 0032801668 scopus 로고    scopus 로고
    • Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase
    • de la Iglesia N, Veiga-da-Cunha M, Van Schaftingen E, Guinovart JJ, Ferrer JC. 1999. Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase. FEBS Lett 456:332-338.
    • (1999) FEBS Lett , vol.456 , pp. 332-338
    • de la Iglesia, N.1    Veiga-da-Cunha, M.2    Van Schaftingen, E.3    Guinovart, J.J.4    Ferrer, J.C.5
  • 16
    • 0028788805 scopus 로고
    • Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1
    • Doherty MJ, Moorhead G, Morrice N, Cohen P, Cohen PT. 1995. Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1. FEBS Lett 375:294-298.
    • (1995) FEBS Lett , vol.375 , pp. 294-298
    • Doherty, M.J.1    Moorhead, G.2    Morrice, N.3    Cohen, P.4    Cohen, P.T.5
  • 17
    • 0016379071 scopus 로고
    • Studies on the kinetics and mechanism of orthophosphate activation of bovine brain hexokinase
    • Ellison WR, Lueck JD, Fromm HJ. 1974. Studies on the kinetics and mechanism of orthophosphate activation of bovine brain hexokinase. Biochem Biophys Res Commun 57:1214-1220.
    • (1974) Biochem Biophys Res Commun , vol.57 , pp. 1214-1220
    • Ellison, W.R.1    Lueck, J.D.2    Fromm, H.J.3
  • 18
    • 0016636347 scopus 로고
    • Studies on the mechanism of orthophosphate regulation of bovine brain hexokinase
    • Ellison WR, Lueck JD, Fromm HJ. 1975. Studies on the mechanism of orthophosphate regulation of bovine brain hexokinase. J Biol Chem 250:1864-1871.
    • (1975) J Biol Chem , vol.250 , pp. 1864-1871
    • Ellison, W.R.1    Lueck, J.D.2    Fromm, H.J.3
  • 20
    • 0026464733 scopus 로고
    • Role of glucose 6-phosphate in the translocation of glycogen synthase in rat hepatocytes
    • Fernandez-Novell JM, Arino J, Vilaro S, Bellido D, Guinovart JJ. 1992. Role of glucose 6-phosphate in the translocation of glycogen synthase in rat hepatocytes. Biochem J 288:497-501.
    • (1992) Biochem J , vol.288 , pp. 497-501
    • Fernandez-Novell, J.M.1    Arino, J.2    Vilaro, S.3    Bellido, D.4    Guinovart, J.J.5
  • 21
    • 0029888220 scopus 로고    scopus 로고
    • Translocation and aggregation of hepatic glycogen synthase during the fasted-to-refed transition in rats
    • Fernandez-Novell JM, Roca A, Bellido D, Vilaro S, Guinovart JJ. 1996. Translocation and aggregation of hepatic glycogen synthase during the fasted-to-refed transition in rats. Eur J Biochem 238:570-575.
    • (1996) Eur J Biochem , vol.238 , pp. 570-575
    • Fernandez-Novell, J.M.1    Roca, A.2    Bellido, D.3    Vilaro, S.4    Guinovart, J.J.5
  • 22
    • 0031033009 scopus 로고    scopus 로고
    • Glucose induces the translocation of glycogen synthase to the cell cortex in rat hepatocytes
    • Fernandez-Novell JM, Bellido D, Vilaro S, Guinovart JJ. 1997. Glucose induces the translocation of glycogen synthase to the cell cortex in rat hepatocytes. Biochem J 321:227-231.
    • (1997) Biochem J , vol.321 , pp. 227-231
    • Fernandez-Novell, J.M.1    Bellido, D.2    Vilaro, S.3    Guinovart, J.J.4
  • 24
    • 0030853642 scopus 로고    scopus 로고
    • Muscle glycogen synthase translocates from the cell nucleus to the cystosol in response to glucose
    • Ferrer JC, Baque S, Guinovart JJ. 1997. Muscle glycogen synthase translocates from the cell nucleus to the cystosol in response to glucose. FEBS Lett 415:249-252.
    • (1997) FEBS Lett , vol.415 , pp. 249-252
    • Ferrer, J.C.1    Baque, S.2    Guinovart, J.J.3
  • 26
    • 0020482168 scopus 로고
    • Evidence for identity between the hexokinase-binding protein and the mitochondrial porin in the outer membrane of rat liver mitochondria
    • Fiek C, Benz R, Roos N, Brdiczka D. 1982. Evidence for identity between the hexokinase-binding protein and the mitochondrial porin in the outer membrane of rat liver mitochondria. Biochim Biophys Acta 688:429-440.
    • (1982) Biochim Biophys Acta , vol.688 , pp. 429-440
    • Fiek, C.1    Benz, R.2    Roos, N.3    Brdiczka, D.4
  • 27
    • 0017352133 scopus 로고
    • A cluster-gene: Evidence for one gene, one polypeptide, five enzymes
    • Gaertner FH, Cole KW. 1977. A cluster-gene: Evidence for one gene, one polypeptide, five enzymes. Biochem Biophys Res Commun 75:259-264.
    • (1977) Biochem Biophys Res Commun , vol.75 , pp. 259-264
    • Gaertner, F.H.1    Cole, K.W.2
  • 29
    • 11244335844 scopus 로고    scopus 로고
    • A distal region involving hepatocyte nuclear factor 4alpha and CAAT/ enhancer binding protein markedly potentiates the protein kinase A stimulation of the glucose-6-phosphatase promoter
    • Gautier-Stein A, Mithieux G, Rajas F. 2005. A distal region involving hepatocyte nuclear factor 4alpha and CAAT/ enhancer binding protein markedly potentiates the protein kinase A stimulation of the glucose-6-phosphatase promoter. Mol Endocrinol 19:163-174.
    • (2005) Mol Endocrinol , vol.19 , pp. 163-174
    • Gautier-Stein, A.1    Mithieux, G.2    Rajas, F.3
  • 30
    • 8744286850 scopus 로고    scopus 로고
    • The glycogenic action of protein targeting to glycogen in hepatocytes involves multiple mechanisms including phosphorylase inactivation and glycogen synthase translocation
    • Green AR, Aiston S, Greenberg CC, Freeman S, Poucher SM, Brady MJ, Agius L. 2004. The glycogenic action of protein targeting to glycogen in hepatocytes involves multiple mechanisms including phosphorylase inactivation and glycogen synthase translocation. J Biol Chem 279:46474-46482.
    • (2004) J Biol Chem , vol.279 , pp. 46474-46482
    • Green, A.R.1    Aiston, S.2    Greenberg, C.C.3    Freeman, S.4    Poucher, S.M.5    Brady, M.J.6    Agius, L.7
  • 34
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 glucose transporter
    • Huang S, Czech MP. 2007. The GLUT4 glucose transporter. Cell Metab 5:237-252.
    • (2007) Cell Metab , vol.5 , pp. 237-252
    • Huang, S.1    Czech, M.P.2
  • 35
    • 0020485742 scopus 로고
    • Pore protein and the hexokinase-binding protein from the outer membrane of rat liver mitochondria are identical
    • Linden M, Gellerfors P, Nelson BD. 1982. Pore protein and the hexokinase-binding protein from the outer membrane of rat liver mitochondria are identical. FEBS Lett 141:189-192.
    • (1982) FEBS Lett , vol.141 , pp. 189-192
    • Linden, M.1    Gellerfors, P.2    Nelson, B.D.3
  • 37
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae J, Kitamura T, Silver DL, Accili D. 2001. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359-1367.
    • (2001) J Clin Invest , vol.108 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 38
    • 0033664155 scopus 로고    scopus 로고
    • Organizing glucose disposal: Emerging roles of the glycogen targeting subunits of protein phosphatase-1
    • Newgard CB, Brady MJ, O'Doherty RM, Saltiel AR. 2000. Organizing glucose disposal: Emerging roles of the glycogen targeting subunits of protein phosphatase-1. Diabetes 49:1967-1977.
    • (2000) Diabetes , vol.49 , pp. 1967-1977
    • Newgard, C.B.1    Brady, M.J.2    O'Doherty, R.M.3    Saltiel, A.R.4
  • 39
    • 0035868681 scopus 로고    scopus 로고
    • Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content
    • Nielsen JN, Derave W, Kristiansen S, Ralston E, Ploug T, Richter EA. 2001. Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content. J Physiol 531:757-769.
    • (2001) J Physiol , vol.531 , pp. 757-769
    • Nielsen, J.N.1    Derave, W.2    Kristiansen, S.3    Ralston, E.4    Ploug, T.5    Richter, E.A.6
  • 40
    • 11144228627 scopus 로고    scopus 로고
    • Spatial reorganization of glycogen synthase upon activation in 3T3-L1 adipocytes
    • Ou H, Yan L, Osmanovic S, Greenberg CC, Brady MJ. 2005. Spatial reorganization of glycogen synthase upon activation in 3T3-L1 adipocytes. Endocrinology 146:494-502.
    • (2005) Endocrinology , vol.146 , pp. 494-502
    • Ou, H.1    Yan, L.2    Osmanovic, S.3    Greenberg, C.C.4    Brady, M.J.5
  • 41
    • 0842345408 scopus 로고    scopus 로고
    • On the origin of intracellular compartmentation and organized metabolic systems
    • Ovadi J, Saks V. 2004. On the origin of intracellular compartmentation and organized metabolic systems. Mol Cell Biochem 256-257:5-12.
    • (2004) Mol Cell Biochem , vol.256-257 , pp. 5-12
    • Ovadi, J.1    Saks, V.2
  • 42
    • 0041309460 scopus 로고    scopus 로고
    • Hexokinase II: The integration of energy metabolism and control of apoptosis
    • Pastorino JG, Hoek JB. 2003. Hexokinase II: The integration of energy metabolism and control of apoptosis. Curr Med Chem 10:1535-1551.
    • (2003) Curr Med Chem , vol.10 , pp. 1535-1551
    • Pastorino, J.G.1    Hoek, J.B.2
  • 46
    • 0026321413 scopus 로고
    • Multisite and hierarchal protein phosphorylation
    • Roach PJ. 1991. Multisite and hierarchal protein phosphorylation. J Biol Chem 266:14139-14142.
    • (1991) J Biol Chem , vol.266 , pp. 14139-14142
    • Roach, P.J.1
  • 47
    • 0022233869 scopus 로고
    • Organization of Krebs tricarboxylic acid cycle enzymes in mitochondria
    • Robinson JB, Jr., Srere PA. 1985. Organization of Krebs tricarboxylic acid cycle enzymes in mitochondria. J Biol Chem 260:10800-10805.
    • (1985) J Biol Chem , vol.260 , pp. 10800-10805
    • Robinson Jr., J.B.1    Srere, P.A.2
  • 48
    • 0026611962 scopus 로고
    • 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus
    • Rothman DL, Shulman RG, Shulman GI. 1992. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. J Clin Invest 89:1069-1075.
    • (1992) J Clin Invest , vol.89 , pp. 1069-1075
    • Rothman, D.L.1    Shulman, R.G.2    Shulman, G.I.3
  • 50
    • 0033601256 scopus 로고    scopus 로고
    • Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
    • Shiota C, Coffey J, Grimsby J, Grippo JF, Magnuson MA. 1999. Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase. J Biol Chem 274:37125-37130.
    • (1999) J Biol Chem , vol.274 , pp. 37125-37130
    • Shiota, C.1    Coffey, J.2    Grimsby, J.3    Grippo, J.F.4    Magnuson, M.A.5
  • 51
    • 0029075837 scopus 로고
    • In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis
    • Shulman RG, Bloch G, Rothman DL. 1995. In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. Proc Natl Acad Sci USA 92:8535-8542.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8535-8542
    • Shulman, R.G.1    Bloch, G.2    Rothman, D.L.3
  • 52
    • 0028072751 scopus 로고
    • Rabbit skeletal muscle glycogen synthase expressed in COS cells. Identification of regulatory phosphorylation sites
    • Skurat AV, Wang Y, Roach PJ. 1994. Rabbit skeletal muscle glycogen synthase expressed in COS cells. Identification of regulatory phosphorylation sites. J Biol Chem 269:25534-25542.
    • (1994) J Biol Chem , vol.269 , pp. 25534-25542
    • Skurat, A.V.1    Wang, Y.2    Roach, P.J.3
  • 53
    • 0014209716 scopus 로고
    • Enzyme concentrations in tissues
    • Srere PA. 1967. Enzyme concentrations in tissues. Science 158:936-937.
    • (1967) Science , vol.158 , pp. 936-937
    • Srere, P.A.1
  • 54
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • Taniguchi CM, Emanuelli B, Kahn CR. 2006. Critical nodes in signalling pathways: Insights into insulin action. Nat Rev Mol Cell Biol 7:85-96.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 56
    • 0028819431 scopus 로고
    • Functional organization of mammalian hexokinases: Characterization of chimeric hexokinases constructed from the N- and C-terminal domains of the rat type I and type II isozymes
    • Tsai HJ, Wilson JE. 1995. Functional organization of mammalian hexokinases: Characterization of chimeric hexokinases constructed from the N- and C-terminal domains of the rat type I and type II isozymes. Arch Biochem Biophys 316:206-214.
    • (1995) Arch Biochem Biophys , vol.316 , pp. 206-214
    • Tsai, H.J.1    Wilson, J.E.2
  • 57
    • 0025341608 scopus 로고
    • The mechanism by which rat liver glucokinase is inhibited by the regulatory protein
    • Vandercammen A, Van Schaftingen E. 1990. The mechanism by which rat liver glucokinase is inhibited by the regulatory protein. Eur J Biochem 191:483-489.
    • (1990) Eur J Biochem , vol.191 , pp. 483-489
    • Vandercammen, A.1    Van Schaftingen, E.2
  • 58
    • 0026074940 scopus 로고
    • Substrate specific activation by glucose 6-phosphate of the dephosphorylation of muscle glycogen synthase
    • Villar-Palasi C. 1991. Substrate specific activation by glucose 6-phosphate of the dephosphorylation of muscle glycogen synthase. Biochim Biophys Acta 1095:261-267.
    • (1991) Biochim Biophys Acta , vol.1095 , pp. 261-267
    • Villar-Palasi, C.1
  • 61
    • 33645997012 scopus 로고    scopus 로고
    • Bridging the GAP between insulin signaling and GLUT4 translocation
    • Watson RT, Pessin JE. 2006. Bridging the GAP between insulin signaling and GLUT4 translocation. Trends Biochem Sci 31:215-222.
    • (2006) Trends Biochem Sci , vol.31 , pp. 215-222
    • Watson, R.T.1    Pessin, J.E.2
  • 62
    • 0023615778 scopus 로고
    • Glycolysis preferentially inhibits ATP-sensitive K+ channels in isolated guinea pig cardiac myocytes
    • Weiss JN, Lamp ST. 1987. Glycolysis preferentially inhibits ATP-sensitive K+ channels in isolated guinea pig cardiac myocytes. Science 238:67-69.
    • (1987) Science , vol.238 , pp. 67-69
    • Weiss, J.N.1    Lamp, S.T.2
  • 63
    • 0031918624 scopus 로고    scopus 로고
    • The IRS-signalling system: A network of docking proteins that mediate insulin action
    • White MF. 1998. The IRS-signalling system: A network of docking proteins that mediate insulin action. Mol Cell Biochem 182:3-11.
    • (1998) Mol Cell Biochem , vol.182 , pp. 3-11
    • White, M.F.1
  • 65
    • 0038714272 scopus 로고    scopus 로고
    • Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function
    • Wilson JE. 2003. Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function. J Exp Biol 206:2049-2057.
    • (2003) J Exp Biol , vol.206 , pp. 2049-2057
    • Wilson, J.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.