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Volumn 64, Issue 5, 2008, Pages 1230-1238

Hepatic transcription factor activation and proinflammatory mediator production is attenuated by hypertonic saline and pentoxifylline resuscitation after hemorrhagic shock

Author keywords

Hemorrhagic shock; Hepatic injury; Hypertonic saline; Ischemia reperfusion; Pentoxifylline

Indexed keywords

AMINOTRANSFERASE; HIGH MOBILITY GROUP B1 PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRITE; PENTOXIFYLLINE; RINGER LACTATE SOLUTION; SODIUM CHLORIDE; STAT3 PROTEIN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 43449116671     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e31816a4391     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 0029932697 scopus 로고    scopus 로고
    • Prevention and therapy of multiple organ failure
    • Vincent JL. Prevention and therapy of multiple organ failure. World J Surg. 1996;20:465-470.
    • (1996) World J Surg , vol.20 , pp. 465-470
    • Vincent, J.L.1
  • 2
    • 0026744448 scopus 로고
    • Multiple organ failure: Pathophysiology and potential future therapy
    • Deitch EA. Multiple organ failure: pathophysiology and potential future therapy. Ann Surg. 1992;216:117-134.
    • (1992) Ann Surg , vol.216 , pp. 117-134
    • Deitch, E.A.1
  • 3
    • 0028143057 scopus 로고
    • Mediators, mechanism, and mortality in major trauma
    • Donelly SC, Robertson C. Mediators, mechanism, and mortality in major trauma. Resuscitation. 1994;28:87-92.
    • (1994) Resuscitation , vol.28 , pp. 87-92
    • Donelly, S.C.1    Robertson, C.2
  • 4
    • 0028962832 scopus 로고
    • Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma
    • Roumen RM, Redl H, Schlag G, et al. Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma. Crit Care Med. 1995;23:474-480.
    • (1995) Crit Care Med , vol.23 , pp. 474-480
    • Roumen, R.M.1    Redl, H.2    Schlag, G.3
  • 5
    • 0035221277 scopus 로고    scopus 로고
    • Post-injury multiple organ failure: The role of the gut
    • Hassoun HT, Kone BC, Mercer DW, et al. Post-injury multiple organ failure: the role of the gut. Shock. 2001;15:1-10.
    • (2001) Shock , vol.15 , pp. 1-10
    • Hassoun, H.T.1    Kone, B.C.2    Mercer, D.W.3
  • 6
    • 0029792273 scopus 로고    scopus 로고
    • Splanchnic ischemia and gut mucosal injury in sepsis and multiple organ dysfunction syndrome
    • Pastores SM, Katz DP, Kvetan V. Splanchnic ischemia and gut mucosal injury in sepsis and multiple organ dysfunction syndrome. Am J Gastroenterol. 1996;91:1697-1710.
    • (1996) Am J Gastroenterol , vol.91 , pp. 1697-1710
    • Pastores, S.M.1    Katz, D.P.2    Kvetan, V.3
  • 7
    • 0029935286 scopus 로고    scopus 로고
    • Role of the gut in multiple organ failure: Bacterial translocation and permeability changes
    • Swank GM, Deitch EA. Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg. 1996;20:411-417.
    • (1996) World J Surg , vol.20 , pp. 411-417
    • Swank, G.M.1    Deitch, E.A.2
  • 8
    • 0032111014 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in the liver: Regulation and function
    • Taylor BS, Alarcon LH, Billiar TR. Inducible nitric oxide synthase in the liver: regulation and function. Biochemistry. 1998;63:766-781.
    • (1998) Biochemistry , vol.63 , pp. 766-781
    • Taylor, B.S.1    Alarcon, L.H.2    Billiar, T.R.3
  • 9
    • 0036365190 scopus 로고    scopus 로고
    • The modulation of hepatic injury and heat shock expression by inhibition of nitric oxide synthase after hemorrhagic shock
    • Menezes JM, Hierholzer C, Watkins SC, et al. The modulation of hepatic injury and heat shock expression by inhibition of nitric oxide synthase after hemorrhagic shock. Shock. 2002;17:13-18.
    • (2002) Shock , vol.17 , pp. 13-18
    • Menezes, J.M.1    Hierholzer, C.2    Watkins, S.C.3
  • 10
    • 0032536875 scopus 로고    scopus 로고
    • Essential role of inducible nitric oxide in the initiation of the inflammatory response after hemorrhagic shock
    • Hierholzer C, Harbrecht B, Menezes JM, et al. Essential role of inducible nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med. 1998;187:917-928.
    • (1998) J Exp Med , vol.187 , pp. 917-928
    • Hierholzer, C.1    Harbrecht, B.2    Menezes, J.M.3
  • 11
    • 0037229864 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning
    • Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol. 2003;284:G15-G26.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Jaeschke, H.1
  • 12
    • 0141594593 scopus 로고    scopus 로고
    • Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
    • Jaeschke H, Lemasters JJ. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology. 2003; 125:1246-1257.
    • (2003) Gastroenterology , vol.125 , pp. 1246-1257
    • Jaeschke, H.1    Lemasters, J.J.2
  • 13
    • 1542316768 scopus 로고    scopus 로고
    • Extracellular role of HMGB1 in inflammation and sepsis
    • Wang H, Yang H, Tracey KJ. Extracellular role of HMGB1 in inflammation and sepsis. J Int Med. 2004;255:320-331.
    • (2004) J Int Med , vol.255 , pp. 320-331
    • Wang, H.1    Yang, H.2    Tracey, K.J.3
  • 14
    • 3242693560 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 as a proinflammatory mediator
    • Erlandsson H, Andersson U. The nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol. 2004;34:1503-1512.
    • (2004) Eur J Immunol , vol.34 , pp. 1503-1512
    • Erlandsson, H.1    Andersson, U.2
  • 15
    • 33747345872 scopus 로고    scopus 로고
    • Bioactivity of post-shock mesenteric lymph depends on the depth and duration of hemorrhagic shock
    • Masuno T, Moore EE, Cheng AM, et al. Bioactivity of post-shock mesenteric lymph depends on the depth and duration of hemorrhagic shock. Shock. 2006;26:285-289.
    • (2006) Shock , vol.26 , pp. 285-289
    • Masuno, T.1    Moore, E.E.2    Cheng, A.M.3
  • 16
    • 1342279608 scopus 로고    scopus 로고
    • Effect of different resuscitation strategies on neutrophil activation in a swine model of hemorrhagic shock
    • Alam HB, Stanton K, Koustova E, et al. Effect of different resuscitation strategies on neutrophil activation in a swine model of hemorrhagic shock. Resuscitation. 2004;60:91-99.
    • (2004) Resuscitation , vol.60 , pp. 91-99
    • Alam, H.B.1    Stanton, K.2    Koustova, E.3
  • 17
    • 0033674561 scopus 로고    scopus 로고
    • E- and P-selectin expression depends on the resuscitation fluid used in hemorrhaged rats
    • Alam HB, Sun L, Ruff P, et al. E- and P-selectin expression depends on the resuscitation fluid used in hemorrhaged rats. J Surg Res. 2000;94:145-152.
    • (2000) J Surg Res , vol.94 , pp. 145-152
    • Alam, H.B.1    Sun, L.2    Ruff, P.3
  • 18
    • 27844599616 scopus 로고    scopus 로고
    • Endothelial dysfunction after lactated ringer's solution resuscitation for hemorrhagic shock
    • Savage SA, Fitzpatrick CM, Kashyap V, et al. Endothelial dysfunction after lactated ringer's solution resuscitation for hemorrhagic shock. J Trauma. 2005;59:284-290.
    • (2005) J Trauma , vol.59 , pp. 284-290
    • Savage, S.A.1    Fitzpatrick, C.M.2    Kashyap, V.3
  • 19
    • 0032014985 scopus 로고    scopus 로고
    • Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock
    • Angle N, Hoyt DB, Liu F, et al. Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock. Shock. 1998;9:164-170.
    • (1998) Shock , vol.9 , pp. 164-170
    • Angle, N.1    Hoyt, D.B.2    Liu, F.3
  • 20
    • 0025040436 scopus 로고
    • Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock
    • Barroso-Aranda J, Schmid-Schonbein GW. Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock. Biorheology. 1990;27:401-418.
    • (1990) Biorheology , vol.27 , pp. 401-418
    • Barroso-Aranda, J.1    Schmid-Schonbein, G.W.2
  • 21
    • 27844463498 scopus 로고    scopus 로고
    • Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-α synthesis: A novel resuscitation strategy
    • Coimbra R, Loomis WH, Melbostad H, et al. Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-α synthesis: a novel resuscitation strategy. J Trauma. 2005; 59:257-265.
    • (2005) J Trauma , vol.59 , pp. 257-265
    • Coimbra, R.1    Loomis, W.H.2    Melbostad, H.3
  • 22
    • 33646107892 scopus 로고    scopus 로고
    • HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: An attractive alternative to ringer's lactate
    • Coimbra R, Porcides R, Loomis WH, et al. HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: an attractive alternative to ringer's lactate. J Trauma. 2006;60:41-51.
    • (2006) J Trauma , vol.60 , pp. 41-51
    • Coimbra, R.1    Porcides, R.2    Loomis, W.H.3
  • 23
    • 33846203391 scopus 로고    scopus 로고
    • Hypertonic saline and pentoxifylline educes hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and pro-inflammatory mediator synthesis
    • Deree J, Martins JO, Leedom A, et al. Hypertonic saline and pentoxifylline educes hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and pro-inflammatory mediator synthesis. J Trauma. 2007;62:104-111.
    • (2007) J Trauma , vol.62 , pp. 104-111
    • Deree, J.1    Martins, J.O.2    Leedom, A.3
  • 24
    • 34247237289 scopus 로고    scopus 로고
    • Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: The kinder, gentler resuscitation
    • Deree J, de Campos T, Shenvi E, et al. Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation. J Trauma. 2007;62:818-827.
    • (2007) J Trauma , vol.62 , pp. 818-827
    • Deree, J.1    de Campos, T.2    Shenvi, E.3
  • 25
    • 17444444908 scopus 로고    scopus 로고
    • Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol
    • Sneed RA, Grimes SD, Schultze AE, et al. Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol. Toxicol Appl Pharmacol. 1997;144:77-87.
    • (1997) Toxicol Appl Pharmacol , vol.144 , pp. 77-87
    • Sneed, R.A.1    Grimes, S.D.2    Schultze, A.E.3
  • 26
    • 19044389392 scopus 로고    scopus 로고
    • Nonspecific phosphodiesterase inhibition attenuates liver injury in acute endotoxemia
    • Coimbra R, Porcides RD, Melbostad H, et al. Nonspecific phosphodiesterase inhibition attenuates liver injury in acute endotoxemia. Surg Infect. 2005;6:73-85.
    • (2005) Surg Infect , vol.6 , pp. 73-85
    • Coimbra, R.1    Porcides, R.D.2    Melbostad, H.3
  • 27
    • 0003055186 scopus 로고    scopus 로고
    • The role of nitric oxide in sepsis-an overview
    • Kirkeboen KA, Strand OA. The role of nitric oxide in sepsis-an overview. Acta Anaesthesiol Scand. 1999;43:275-288.
    • (1999) Acta Anaesthesiol Scand , vol.43 , pp. 275-288
    • Kirkeboen, K.A.1    Strand, O.A.2
  • 28
    • 0030610685 scopus 로고    scopus 로고
    • Activation of the NF-kB pathway by inflammatory stimuli in human neutrophils
    • McDonald PP, Bald A, Cassatella MA. Activation of the NF-kB pathway by inflammatory stimuli in human neutrophils. Blood. 1997; 89:3421-3433.
    • (1997) Blood , vol.89 , pp. 3421-3433
    • McDonald, P.P.1    Bald, A.2    Cassatella, M.A.3
  • 29
    • 0034685542 scopus 로고    scopus 로고
    • Inducible NF-kB activation is permitted by simultaneous degradation of nuclear IkB-α
    • Renard P, Percherancier Y, Kroll M, et al. Inducible NF-kB activation is permitted by simultaneous degradation of nuclear IkB-α. J Biol Chem. 2000;275:15193-15199.
    • (2000) J Biol Chem , vol.275 , pp. 15193-15199
    • Renard, P.1    Percherancier, Y.2    Kroll, M.3
  • 30
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-kB
    • Schmitz ML, Baeuerle PA. The p65 subunit is responsible for the strong transcription activating potential of NF-kB. EMBO J. 1991; 10:3805-3817.
    • (1991) EMBO J , vol.10 , pp. 3805-3817
    • Schmitz, M.L.1    Baeuerle, P.A.2
  • 31
    • 0042736093 scopus 로고    scopus 로고
    • Amplification of the pro-inflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine
    • Brundage SI, Schreiber MA, Holcomb JB, et al. Amplification of the pro-inflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine. J Surg Res. 2003; 113:74-80.
    • (2003) J Surg Res , vol.113 , pp. 74-80
    • Brundage, S.I.1    Schreiber, M.A.2    Holcomb, J.B.3
  • 32
    • 20244373939 scopus 로고    scopus 로고
    • The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
    • Tsung A, Sahai R, Tanaka H, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med. 2005;210:1135-1143.
    • (2005) J Exp Med , vol.210 , pp. 1135-1143
    • Tsung, A.1    Sahai, R.2    Tanaka, H.3
  • 33
    • 34548378391 scopus 로고    scopus 로고
    • Outcome after hemorrhagic shock in trauma patients
    • Heckbert SR, Vedder NB, Hoffmann W, et al. Outcome after hemorrhagic shock in trauma patients. Am J Physiol. 1998;45:545-549.
    • (1998) Am J Physiol , vol.45 , pp. 545-549
    • Heckbert, S.R.1    Vedder, N.B.2    Hoffmann, W.3
  • 34
    • 27544464684 scopus 로고    scopus 로고
    • The liver and hemorrhagic shock
    • Helling TS. The liver and hemorrhagic shock. J Am Coll Surg. 2005; 201:774-783.
    • (2005) J Am Coll Surg , vol.201 , pp. 774-783
    • Helling, T.S.1
  • 35
    • 0036024424 scopus 로고    scopus 로고
    • cDNA array analysis of gene expression following hemorrhagic shock and resuscitation in rats
    • Alam HB, Stegalkina S, Rhee P, et al. cDNA array analysis of gene expression following hemorrhagic shock and resuscitation in rats. Resuscitation. 2002;54:195-206.
    • (2002) Resuscitation , vol.54 , pp. 195-206
    • Alam, H.B.1    Stegalkina, S.2    Rhee, P.3
  • 36
    • 0036098545 scopus 로고    scopus 로고
    • Effects of lactated ringer's solutions on human leukocytes
    • Koustova E, Stanton K, Gushchin V, et al. Effects of lactated ringer's solutions on human leukocytes. J Trauma. 2002;52:872-878.
    • (2002) J Trauma , vol.52 , pp. 872-878
    • Koustova, E.1    Stanton, K.2    Gushchin, V.3
  • 37
    • 0036829826 scopus 로고    scopus 로고
    • Hypertonic saline resuscitation of hemorrhagic shock diminishes neutrophil rolling and adherence to endothelium and reduced in vivo vascular leakage
    • Pascual JL, Ferri LE, Seely AJ, et al. Hypertonic saline resuscitation of hemorrhagic shock diminishes neutrophil rolling and adherence to endothelium and reduced in vivo vascular leakage. Ann Surg. 2002; 236:634-642.
    • (2002) Ann Surg , vol.236 , pp. 634-642
    • Pascual, J.L.1    Ferri, L.E.2    Seely, A.J.3
  • 38
    • 0030968482 scopus 로고    scopus 로고
    • Pentoxifylline prevents endothelial damage due to ischemia and reperfusion injury
    • Coe DA, Freischlag JA, Johnson D, et al. Pentoxifylline prevents endothelial damage due to ischemia and reperfusion injury. J Surg Res. 1997;67:21-25.
    • (1997) J Surg Res , vol.67 , pp. 21-25
    • Coe, D.A.1    Freischlag, J.A.2    Johnson, D.3
  • 39
    • 53949109640 scopus 로고    scopus 로고
    • Pentoxifylline-supplemented resuscitation attenuates both early and late mediators of hepatic inflammation after hemorrhagic shock
    • In press
    • Deree J, Loomis WH, Putnam JG, et al. Pentoxifylline-supplemented resuscitation attenuates both early and late mediators of hepatic inflammation after hemorrhagic shock. J Organ Dysfunct. In press.
    • J Organ Dysfunct
    • Deree, J.1    Loomis, W.H.2    Putnam, J.G.3
  • 40
    • 1542346788 scopus 로고    scopus 로고
    • Effects of phosphodiesterase inhibition on the inflammatory response after shock: Role of pentoxifylline
    • Coimbra R, Melbostad H, Hoyt DB. Effects of phosphodiesterase inhibition on the inflammatory response after shock: role of pentoxifylline. J Trauma. 2004;56:442-449.
    • (2004) J Trauma , vol.56 , pp. 442-449
    • Coimbra, R.1    Melbostad, H.2    Hoyt, D.B.3
  • 41
    • 33645893751 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase prevents hepatic, but not pulmonary, injury following ischemia-reperfusion injury of rat liver
    • Takamatsu Y, Shimada K, Yamaguchi K, et al. Inhibition of inducible nitric oxide synthase prevents hepatic, but not pulmonary, injury following ischemia-reperfusion injury of rat liver. Dig Dis Sci. 2006;51:571-579.
    • (2006) Dig Dis Sci , vol.51 , pp. 571-579
    • Takamatsu, Y.1    Shimada, K.2    Yamaguchi, K.3
  • 42
    • 0038677102 scopus 로고    scopus 로고
    • Reduced hepatic transcription factor activation and expression of IL-6 and ICAM-1 after hemorrhage by NO scavenging
    • Hierholzer C, Billiar TR, Tweardy DJ, et al. Reduced hepatic transcription factor activation and expression of IL-6 and ICAM-1 after hemorrhage by NO scavenging. Arch Orthop Trauma Surg. 2003;123:55-59.
    • (2003) Arch Orthop Trauma Surg , vol.123 , pp. 55-59
    • Hierholzer, C.1    Billiar, T.R.2    Tweardy, D.J.3
  • 43
    • 13544261749 scopus 로고    scopus 로고
    • Superoxide potentiates NF-kB activation and modulates endotoxin-induced cytokine production in alveolar macrophages
    • Ndengele MM, Muscoli C, Wang ZQ, et al. Superoxide potentiates NF-kB activation and modulates endotoxin-induced cytokine production in alveolar macrophages. Shock. 2005;23:186-193.
    • (2005) Shock , vol.23 , pp. 186-193
    • Ndengele, M.M.1    Muscoli, C.2    Wang, Z.Q.3
  • 45
    • 2942652398 scopus 로고    scopus 로고
    • Extracellular HMGB1 as a proinflammatory cytokine
    • Chen G, Ward MF, Sama AE, et al. Extracellular HMGB1 as a proinflammatory cytokine. J Interferon Cytokine Res. 2004;24:329-333.
    • (2004) J Interferon Cytokine Res , vol.24 , pp. 329-333
    • Chen, G.1    Ward, M.F.2    Sama, A.E.3
  • 46
    • 33745825536 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase expressed by alveolar macrophages in high mobility group box 1-induced acute lung injury
    • Ren D, Sun R, Wang S. Role of inducible nitric oxide synthase expressed by alveolar macrophages in high mobility group box 1-induced acute lung injury. Inflamm Res. 2006;55:207-215.
    • (2006) Inflamm Res , vol.55 , pp. 207-215
    • Ren, D.1    Sun, R.2    Wang, S.3
  • 47
    • 0041942745 scopus 로고    scopus 로고
    • Gastric mucosal acidosis and cytokine release in patients with septic shock
    • Tamion F, Richard V, Sauger F, et al. Gastric mucosal acidosis and cytokine release in patients with septic shock. Crit Care Med. 2003; 31:2137-2143.
    • (2003) Crit Care Med , vol.31 , pp. 2137-2143
    • Tamion, F.1    Richard, V.2    Sauger, F.3
  • 48
    • 33646180457 scopus 로고    scopus 로고
    • The synergistic effects of pentoxifylline on systemic and regional perfusion after hemorrhage and hypertonic resuscitation
    • Cruz RJ, Yada-Langui MM, Poli de Figueiredo LF, et al. The synergistic effects of pentoxifylline on systemic and regional perfusion after hemorrhage and hypertonic resuscitation. Anesth Analg. 2006;102:1518-1524.
    • (2006) Anesth Analg , vol.102 , pp. 1518-1524
    • Cruz, R.J.1    Yada-Langui, M.M.2    Poli de Figueiredo, L.F.3


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