Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 370, Issue 1, 2004, Pages 1-8

  Höcht, Christian ^a   Di Verniero, Carla ^a   Opezzo, Javier A W ^a   Taira, Carlos A ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Aortic coarctation; Hypertension; Inverse agonism; Metoprolol; Microdialysis; Pharmacokinetic; Adrenoceptor

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA COARCTATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; BRADYCARDIA; CHRONOTROPISM; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG ACTIVITY; DRUG MECHANISM; DRUG METABOLISM; FEMALE; HEART INNERVATION; HYPERTENSION; MEAN ARTERIAL PRESSURE; NONHUMAN; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; RAT; RECEPTOR BINDING; SYMPATHETIC TONE;

EID: 4344715979     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-0945-2     Document Type: Article

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