Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats

Pharmacology

Volumn 70, Issue 1, 2004, Pages 23-30

  Höcht, Christian ^a   Opezzo, Javier A W ^a   Taira, Carlos A ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

'Shunt' probe; Anterior hypothalamus; Aortic coarctation; Cardiovascular effect, irbesartan; Irbesartan; Microdialysis; Plasma pharmacokinetics, irbesartan

Indexed keywords

IRBESARTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR HYPOTHALAMUS; AORTA COARCTATION; AREA UNDER THE CURVE; ARTERIAL PRESSURE; ARTERY BYPASS; ARTICLE; BLOOD ANALYSIS; BLOOD PRESSURE REGULATION; BLOOD SAMPLING; CAROTID ARTERY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG ELIMINATION; DRUG PROTEIN BINDING; FEMALE; HEART RATE VARIABILITY; HYPOTENSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANGIOTENSIN II; ANIMALS; AORTA; AORTIC COARCTATION; BIPHENYL COMPOUNDS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FEMALE; HEART RATE; HYPOTHALAMUS, ANTERIOR; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; METABOLIC CLEARANCE RATE; MICRODIALYSIS; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 2; TETRAZOLES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 17644431325     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000074239     Document Type: Article

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