-
1
-
-
0004162840
-
Metoprolol
-
Scriabine A ed Raven Press, New York.
-
Ablad B, Carlsson E, Johansson and Regârdh C-G (1980) Metoprolol, in Pharmacology of Antihypertensive Drugs (Scriabine A ed) pp 247-262, Raven Press, New York.
-
(1980)
Pharmacology of Antihypertensive Drugs
, pp. 247-262
-
-
Ablad, B.1
Carlsson, E.2
Johansson3
Regârdh, C.-G.4
-
2
-
-
0025259178
-
The relationship between metoprolol plasma concentration and betarblockade in healthy subjects: A study on conventional metoprolol and metoprolol CR/ZOK formulations
-
Abrahamsson B, Lücker P, Olofsson B, Regârdh C-G, Sandberg A, Wieseigren I and Bergstrand R (1990) The relationship between metoprolol plasma concentration and betarblockade in healthy subjects: A study on conventional metoprolol and metoprolol CR/ZOK formulations. J Clin Pharmacol 30:S46-S54.
-
(1990)
J Clin Pharmacol
, vol.30
-
-
Abrahamsson, B.1
Lücker, P.2
Olofsson, B.3
Regârdh, C.-G.4
Sandberg, A.5
Wieseigren, I.6
Bergstrand, R.7
-
3
-
-
0022196924
-
Effects of the β2-adrenoceptor antagonist ICI 118,551 on exercise tachycardia and isoprenaline-induced β-adrenoceptor responses in man
-
Arnold JMO, O'Connor PC, Riddell JG, Harron DWG, Shanks RG and McDevitt DC (1985) Effects of the β2-adrenoceptor antagonist ICI 118,551 on exercise tachycardia and isoprenaline-induced β-adrenoceptor responses in man. Br J Clin Pharmacol 19:619-630.
-
(1985)
Br J Clin Pharmacol
, vol.19
, pp. 619-630
-
-
Arnold, J.M.O.1
O'Connor, P.C.2
Riddell, J.G.3
Harron, D.W.G.4
Shanks, R.G.5
McDevitt, D.C.6
-
4
-
-
0003747347
-
-
Beal SL and Sheiner LB eds NONMEM Project Group, University of California at San Francisco, San Francisco.
-
Beal SL and Sheiner LB eds (1992) NONMEM Users Guides. NONMEM Project Group, University of California at San Francisco, San Francisco.
-
(1992)
NONMEM Users Guides.
-
-
-
5
-
-
0021058778
-
Coexistence of βr and β2'aQ'renoceptors in human right atrium
-
Brodde O-E, Karad K, Zerkowski H-R, Rohm N and Reidemeister JC (1983) Coexistence of βr and β2'aQ'renoceptors in human right atrium. Circ Res 53:752-758.
-
(1983)
Circ Res
, vol.53
, pp. 752-758
-
-
Brodde, O.E.1
Karad, K.2
Zerkowski, H.R.3
Rohm, N.4
Reidemeister, J.C.5
-
6
-
-
0017745302
-
Metoprolol: A review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris
-
Brogden RN, Heel RC, Speight TM and Avery GS (1977) Metoprolol: A review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris. Drugs 14:321-348.
-
(1977)
Drugs
, vol.14
, pp. 321-348
-
-
Brogden, R.N.1
Heel, R.C.2
Speight, T.M.3
Avery, G.S.4
-
7
-
-
0023742912
-
Alteration of the pharmacokinetics and metabolism of propranolol and antipyrine elicited by indwelling catheters in the rat
-
Chindavijak B, Belpaire FM, De Smet F and Bogaert MG (1988) Alteration of the pharmacokinetics and metabolism of propranolol and antipyrine elicited by indwelling catheters in the rat. J Pharmacol Exp Ther 246:1075-1079.
-
(1988)
J Pharmacol Exp Ther
, vol.246
, pp. 1075-1079
-
-
Chindavijak, B.1
Belpaire, F.M.2
De Smet, F.3
Bogaert, M.G.4
-
8
-
-
0015643797
-
The disposition of propranolol. III. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat
-
Evans GH, Nies AS and Shand DG (1973) The disposition of propranolol. III. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat. J Pharmacol Exp Ther 186:114-122.
-
(1973)
J Pharmacol Exp Ther
, vol.186
, pp. 114-122
-
-
Evans, G.H.1
Nies, A.S.2
Shand, D.G.3
-
9
-
-
0000722192
-
Multicompartment models
-
Marcel Dekker, Inc., New York.
-
Gibaldi M and Ferner D (1982) Multicompartment models. Pharmacokinetics, 2nd ed pp 45-111, Marcel Dekker, Inc., New York.
-
(1982)
Pharmacokinetics, 2nd Ed
, pp. 45-111
-
-
Gibaldi, M.1
Ferner, D.2
-
10
-
-
0019442342
-
Assessment of beta blockade with propranolol
-
Hager WD, Pieniaszek HJ, Ferner Jr BA, Mayersohn M and Goldberger V (1981) Assessment of beta blockade with propranolol. Clin Pharmacol Ther 30:283-290.
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 283-290
-
-
Hager, W.D.1
Pieniaszek, H.J.2
Ferner Jr., B.A.3
Mayersohn, M.4
Goldberger, V.5
-
11
-
-
0023920602
-
The dose in humans at which ICI 188,551 (a selective β2-adrenoceptor blocking agent) demonstrates blockade of 3radrenoceptors
-
Harry JD, Norris SC, Percival GC and Young J (1988) The dose in humans at which ICI 188,551 (a selective β2-adrenoceptor blocking agent) demonstrates blockade of (3radrenoceptors. Clin Pharmacol Ther 43:492-498.
-
(1988)
Clin Pharmacol Ther
, vol.43
, pp. 492-498
-
-
Harry, J.D.1
Norris, S.C.2
Percival, G.C.3
Young, J.4
-
12
-
-
0000217817
-
Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
-
Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Oilman AG eds McGraw-Hill, Inc., New York.
-
Huffman BB and Lefkowitz RJ (1996) Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists, in Goodman & Oilman's The Pharmacological Basis of Therapeutics, 9th ed (Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Oilman AG eds) pp 199-248, McGraw-Hill, Inc., New York.
-
(1996)
Goodman & Oilman's the Pharmacological Basis of Therapeutics, 9th Ed
, pp. 199-248
-
-
Huffman, B.B.1
Lefkowitz, R.J.2
-
14
-
-
0028299212
-
A simple and rapid fluorometric determination method of aracid glycoprotein in serum using quinaldine red
-
Imamura H, Maruyama T, Okabe H, Shimada H and Otagiri M (1994) A simple and rapid fluorometric determination method of aracid glycoprotein in serum using quinaldine red. Pharm Res 11:566-570.
-
(1994)
Pharm Res
, vol.11
, pp. 566-570
-
-
Imamura, H.1
Maruyama, T.2
Okabe, H.3
Shimada, H.4
Otagiri, M.5
-
15
-
-
0002322365
-
Xpose-an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM
-
in press
-
Jonsson EN and Karlsson MO (1998) Xpose-an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM. Comp Methods Prog Med, in press.
-
(1998)
Comp Methods Prog Med
-
-
Jonsson, E.N.1
Karlsson, M.O.2
-
16
-
-
0023629433
-
Propranolol pharmacodynamic modeling using unbound and total concentrations in health y volunteers
-
Lalonde RL, Straka RJ, Pieper JA, Bottorff MB and Mirvis DM (1987) Propranolol pharmacodynamic modeling using unbound and total concentrations in health y volunteers. J Pharmacokin Biopharm 15:569-582.
-
(1987)
J Pharmacokin Biopharm
, vol.15
, pp. 569-582
-
-
Lalonde, R.L.1
Straka, R.J.2
Pieper, J.A.3
Bottorff, M.B.4
Mirvis, D.M.5
-
17
-
-
0023152920
-
Effect of surgery on serum j-acid glycoprotein concentration and serum protein binding of d/-propranolol in phenobarbital-treated and untreated rats
-
Lin T-H, Sugiyama Y, Sawada Y, Suzuki Y, Iga T and Hanano M (1987) Effect of surgery on serum j-acid glycoprotein concentration and serum protein binding of d/-propranolol in phenobarbital-treated and untreated rats. Drug Metab Dispos 15:138-140.
-
(1987)
Drug Metab Dispos
, vol.15
, pp. 138-140
-
-
Lin, T.-H.1
Sugiyama, Y.2
Sawada, Y.3
Suzuki, Y.4
Iga, T.5
Hanano, M.6
-
18
-
-
0026035221
-
A dose-ranging study to evaluate the βradrenoceptor selectivity of bisoprolol
-
Lipworth BJ, Irvine NA and McDevitt DG (1991) A dose-ranging study to evaluate the βradrenoceptor selectivity of bisoprolol. Eur J Clin Pharmacol 40:135-139.
-
(1991)
Eur J Clin Pharmacol
, vol.40
, pp. 135-139
-
-
Lipworth, B.J.1
Irvine, N.A.2
McDevitt, D.G.3
-
19
-
-
0023353703
-
Characterization of beta-1 and beta-2 adrenoceptors in guinea pig atrium: Functional and receptor binding studies
-
Molenaar P and Summers RJ (1987) Characterization of beta-1 and beta-2 adrenoceptors in guinea pig atrium: Functional and receptor binding studies. J Pharmc.col Exp Ther 241:1041-1047.
-
(1987)
J Pharmc.col Exp Ther
, vol.241
, pp. 1041-1047
-
-
Molenaar, P.1
Summers, R.J.2
-
20
-
-
0025239913
-
Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade
-
Murray KT, Reilly C, Koshakji RP, Roden DM, Lineberry MD, Wood AJJ, Siddoway LA, Barbey JT and Woosely RL (1990) Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade. J Clin Invest 85:836-842.
-
(1990)
J Clin Invest
, vol.85
, pp. 836-842
-
-
Murray, K.T.1
Reilly, C.2
Koshakji, R.P.3
Roden, D.M.4
Lineberry, M.D.5
Wood, A.J.J.6
Siddoway, L.A.7
Barbey, J.T.8
Woosely, R.L.9
-
21
-
-
11144307183
-
Pharmacodynamics
-
Mansch C, Sammes PG and Taylor JB eds Pergamon Press, Oxford.
-
Paalzow LK (1990) Pharmacodynamics, in Comprehensive Medical Chemistry, Biopharmaceutics (Mansch C, Sammes PG and Taylor JB eds) pp 333-358, Pergamon Press, Oxford.
-
(1990)
Comprehensive Medical Chemistry, Biopharmaceutics
, pp. 333-358
-
-
Paalzow, L.K.1
-
22
-
-
0018572957
-
Multiple receptor responses: A new concept to describe the relationship between pharmacological effects and pharmacokinetics of a drug: Studies on clonidine in the rat and cat
-
Paalzow LK and Edlund PO (1979) Multiple receptor responses: A new concept to describe the relationship between pharmacological effects and pharmacokinetics of a drug: Studies on clonidine in the rat and cat. J Pharmacokin Biopharm 7:495 510.
-
(1979)
J Pharmacokin Biopharm
, vol.7
, pp. 495510
-
-
Paalzow, L.K.1
Edlund, P.O.2
-
23
-
-
0023698164
-
Characterization of the betaadrenoceptors which mediate the isoprenaline-induced changes in finger tremor and cardiovascular function in man
-
Pringle TH, Riddell JG and Shanks RG (1988) Characterization of the betaadrenoceptors which mediate the isoprenaline-induced changes in finger tremor and cardiovascular function in man. Eur J Clin Pharmacol 35:507-514.
-
(1988)
Eur J Clin Pharmacol
, vol.35
, pp. 507-514
-
-
Pringle, T.H.1
Riddell, J.G.2
Shanks, R.G.3
-
24
-
-
0017649448
-
Association of in vivo and in vitro propranolol levels in canine Purkinje fibers with antiarrhythmic effects
-
Pruett JK, Walle T arid Bagwell EE (1977) Association of in vivo and in vitro propranolol levels in canine Purkinje fibers with antiarrhythmic effects. J Pharmacol Exp Ther 202:45-54.
-
(1977)
J Pharmacol Exp Ther
, vol.202
, pp. 45-54
-
-
Pruett, J.K.1
Walle, T.2
Arid Bagwell, E.E.3
-
25
-
-
0019147708
-
Propranolol effects on membrane repolarization time in isolated canine Purkinje fibers: Threshold tissue content and the influence of exposure time
-
Pruett JK, Walle T and Walle UK (1980) Propranolol effects on membrane repolarization time in isolated canine Purkinje fibers: Threshold tissue content and the influence of exposure time. J Pharmacol Exp Ther 215:539-543.
-
(1980)
J Pharmacol Exp Ther
, vol.215
, pp. 539-543
-
-
Pruett, J.K.1
Walle, T.2
Walle, U.K.3
-
26
-
-
0001954570
-
Antiarrhythmic drugs
-
Hardman JG, Limbird LE, Molinoff PE., Ruddon RW, Gilman AG eds McGraw-Hill, Inc., New York.
-
Roden DM (1996) Antiarrhythmic drugs, in Goodman & Oilman's The Pharmacological Basis of Therapeutics, 9th ed (Hardman JG, Limbird LE, Molinoff PE., Ruddon RW, Gilman AG eds) pp 839-874, McGraw-Hill, Inc., New York.
-
(1996)
Goodman & Oilman's the Pharmacological Basis of Therapeutics, 9th Ed
, pp. 839-874
-
-
Roden, D.M.1
-
27
-
-
0024342630
-
Determination of metoprolol and its a-hydroxida metabolite in serum by reversed-phase high-performance liquid Chromatograph}
-
Rutledge RD and Garrick C (1989) Determination of metoprolol and its a-hydroxida metabolite in serum by reversed-phase high-performance liquid Chromatograph}. J Chromatogr Sei 27:561-565.
-
(1989)
J Chromatogr Sei
, vol.27
, pp. 561-565
-
-
Rutledge, R.D.1
Garrick, C.2
-
29
-
-
0029032224
-
Racial differences in sensitivity to the negative chronotropic effects of propranolol in healthy men
-
Sowinski KM, Burlew BS and Johnson JA (1995) Racial differences in sensitivity to the negative chronotropic effects of propranolol in healthy men. Clin Pharmacol Ther 57:678-683.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 678-683
-
-
Sowinski, K.M.1
Burlew, B.S.2
Johnson, J.A.3
-
30
-
-
8244229950
-
-
StatSci, a division of Mathsoft Inc., Seattle, WA.
-
Statistical Sciences Inc. (1993) S-PLUS Reference Manual, version 3.3. StatSci, a division of Mathsoft Inc., Seattle, WA.
-
(1993)
S-PLUS Reference Manual, Version 3.3.
-
-
-
31
-
-
0021026583
-
Alterations in serum protein binding and pharmacokinetics of/-propranolol in the rat elicited by the presence of an indwelling venom catheter
-
Terao N and Shen DD 11983) Alterations in serum protein binding and pharmacokinetics of/-propranolol in the rat elicited by the presence of an indwelling venom catheter. J Pharmacol Exp Ther 227:369-375.
-
(1983)
J Pharmacol Exp Ther
, vol.227
, pp. 369-375
-
-
Terao, N.1
Shen, D.D.2
-
32
-
-
0021266018
-
Comparison of rat and human left ventricle beta-adrenergic receptors: Subtype heterogeneity delineated by direct radioligand binding
-
Vago T, Bevilacqua M, Dagani R, Meroni R, Frigeni G, Santoliβ C and Norbiato (J (1984) Comparison of rat and human left ventricle beta-adrenergic receptors: Subtype heterogeneity delineated by direct radioligand binding. Biochem Biophy.i Res Comm 121:346-354.
-
(1984)
Biochem Biophy.i Res Comm
, vol.121
, pp. 346-354
-
-
Vago, T.1
Bevilacqua, M.2
Dagani, R.3
Meroni, R.4
Frigeni, G.5
Santoli, C.6
Norbiato7
-
34
-
-
0016173684
-
A safe method for rapidly achieving plasma concentration plateaus
-
Wagner JG (1974) A safe method for rapidly achieving plasma concentration plateaus. Clin Pharmacol Ther 16:691-700.
-
(1974)
Clin Pharmacol Ther
, vol.16
, pp. 691-700
-
-
Wagner, J.G.1
-
35
-
-
0023868442
-
I Stereoselective delivery and actions of beta receptor antagonists
-
Walle T, Webb JG, Bagwell EE, Walle UK, Daniell HB and Gaffney TE (1988I Stereoselective delivery and actions of beta receptor antagonists. Biochem Pharmacol 37:115-124.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 115-124
-
-
Walle, T.1
Webb, J.G.2
Bagwell, E.E.3
Walle, U.K.4
Daniell, H.B.5
Gaffney, T.E.6
-
36
-
-
0022384123
-
Receptor binding of propranolol is the missing link between plasma concentration kinetics and the effect-time course in man
-
Wellstein A, Palm D, Pitschner HF and Beiz GG (1985) Receptor binding of propranolol is the missing link between plasma concentration kinetics and the effect-time course in man. Eur J Pharmacol 29:131-147.
-
(1985)
Eur J Pharmacol
, vol.29
, pp. 131-147
-
-
Wellstein, A.1
Palm, D.2
Pitschner, H.F.3
Beiz, G.G.4
-
37
-
-
33748358723
-
-
van Boxtel CJ, Holford NHG. Danhof M eds Elsevier Science Publishers B. V., Amsterdam.
-
Wellstein A, Woosley RL and Schwartz SL ( 1992) Antiarrhythmic drugs and cardiac glycosides, in The In Vivo Study of Drug Action (van Boxtel CJ, Holford NHG. Danhof M eds) pp 277-301, Elsevier Science Publishers B. V., Amsterdam.
-
(1992)
Antiarrhythmic drugs and cardiac glycosides, in the in Vivo Study of Drug Action
, pp. 277-301
-
-
Wellstein, A.1
Woosley, R.L.2
Schwartz, S.L.3
-
38
-
-
0018669842
-
Suppression of chronic ventricular arrhythmias with propranolol
-
Woosley RL, Kornhauser D, Smith R, Reele S, Higgins SB, Nies AS, Shand DG and Gates JA (1979) Suppression of chronic ventricular arrhythmias with propranolol Circulation 60:819-827.
-
(1979)
Circulation
, vol.60
, pp. 819-827
-
-
Woosley, R.L.1
Kornhauser, D.2
Smith, R.3
Reele, S.4
Higgins, S.B.5
Nies, A.S.6
Shand, D.G.7
Gates, J.A.8
-
39
-
-
0022178315
-
Effect of altered plasma protein binding on pharmacokinetics and pharmacodynamics of propranolol in rats after surgery: Role of aracid glycoprotein
-
Yasuhara M, Fujiwara J, Kitade S, Katayama H, Okumura K and Hori R (1983.1 Effect of altered plasma protein binding on pharmacokinetics and pharmacodynamics of propranolol in rats after surgery: Role of aracid glycoprotein. J Pharmacol Exp Ther 235:513-520.
-
(1983)
J Pharmacol Exp Ther
, vol.235
, pp. 513-520
-
-
Yasuhara, M.1
Fujiwara, J.2
Kitade, S.3
Katayama, H.4
Okumura, K.5
Hori, R.6
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