Characterization of β1-selectivity, adrenoceptor-Gs-protein interaction and inverse agonism of nebivolol in human myocardium

British Journal of Pharmacology

Volumn 132, Issue 8, 2001, Pages 1817-1826

  Maack, C ^a   Tyroller, S ^b   Schnabel, P ^b   Cremers, B ^a   Dabew, E ^a   Sudkamp M ^b   Bohm M ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Heart failure; Human myocardium; Inverse agonism; adrenoceptor antagonists

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BISOPROLOL; BUCINDOLOL; CARVEDILOL; METOPROLOL; NEBIVOLOL; NITRIC OXIDE; PROTEIN G;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL CULTURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HEART CONTRACTION; HUMAN; HUMAN TISSUE; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY;

EID: 0035034991     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703992     Document Type: Article

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