메뉴 건너뛰기




Volumn 66, Issue 3, 2004, Pages 1248-1256

Protective effects of FTY720 on chronic allograft nephropathy by reducing late lymphocytic infiltration

Author keywords

Apoptosis; Chronic rejection; FTY720; Kidney transplantation; Lymphocyte infiltration

Indexed keywords

CYCLOSPORIN A; FINGOLIMOD; INTERLEUKIN 10; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR B; TRANSFORMING GROWTH FACTOR BETA;

EID: 4344660143     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00878.x     Document Type: Article
Times cited : (12)

References (57)
  • 1
    • 0028286469 scopus 로고
    • Chronic transplant rejection
    • HOSTETTER TH: Chronic transplant rejection. Kidney Int 46:266-279, 1994
    • (1994) Kidney Int , vol.46 , pp. 266-279
    • Hostetter, T.H.1
  • 2
    • 0032894945 scopus 로고    scopus 로고
    • Sex hormones and gender-related differences: Their influences on chronic renal allograft rejection
    • MULLER V, SZABO A, VIKLICKY O, et al: Sex hormones and gender-related differences: Their influences on chronic renal allograft rejection. Kidney Int 55:2011-2020, 1999
    • (1999) Kidney Int , vol.55 , pp. 2011-2020
    • Muller, V.1    Szabo, A.2    Viklicky, O.3
  • 3
    • 0027471692 scopus 로고
    • Risk factors for chronic rejection in renal allograft recipients
    • ALMOND PS, MATAS A, GILLINGHAM K, et al: Risk factors for chronic rejection in renal allograft recipients. Transplantation 55:752-757, 1993
    • (1993) Transplantation , vol.55 , pp. 752-757
    • Almond, P.S.1    Matas, A.2    Gillingham, K.3
  • 4
    • 0034142222 scopus 로고    scopus 로고
    • Highly altered Vβ repertoire of T cells infiltrating long-term rejected kidney allografts
    • GAGNE K, BROUARD S, GIRAL M, et al: Highly altered Vβ repertoire of T cells infiltrating long-term rejected kidney allografts. J Immunol 164:1553-1563, 2000
    • (2000) J Immunol , vol.164 , pp. 1553-1563
    • Gagne, K.1    Brouard, S.2    Giral, M.3
  • 5
    • 0035113847 scopus 로고    scopus 로고
    • Cellular and molecular parameters in human renal allograft rejection
    • KAMOUN M: Cellular and molecular parameters in human renal allograft rejection. Clin Biochem 34:29-34, 2000
    • (2000) Clin Biochem , vol.34 , pp. 29-34
    • Kamoun, M.1
  • 6
    • 2542510019 scopus 로고    scopus 로고
    • In vivo migration of lymphocytes in chronically rejecting rat kidney allografts
    • MÜLLER V, HAMAR P, SZABO A, et al: In vivo migration of lymphocytes in chronically rejecting rat kidney allografts. Transplant Int 12:145-151, 1999
    • (1999) Transplant Int , vol.12 , pp. 145-151
    • Müller, V.1    Hamar, P.2    Szabo, A.3
  • 7
    • 0027963153 scopus 로고
    • Infiltration patterns of macrophages and lymphocytes in chronically rejecting rat kidney allografts
    • HEEMANN U, TULLIUS SG, TAMATAMI T, et al: Infiltration patterns of macrophages and lymphocytes in chronically rejecting rat kidney allografts. Transplant Int 7:349-355, 1994
    • (1994) Transplant Int , vol.7 , pp. 349-355
    • Heemann, U.1    Tullius, S.G.2    Tamatami, T.3
  • 8
    • 0032844172 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: An update
    • PAUL LC: Chronic allograft nephropathy: An update. Kidney Int 56:783-793, 1999
    • (1999) Kidney Int , vol.56 , pp. 783-793
    • Paul, L.C.1
  • 10
    • 0035062434 scopus 로고    scopus 로고
    • Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo
    • WAAGA AM, GASSER M, KIST-VAN HOLTHE JE, et al: Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo. J Clin Invest 107:909-916, 2001
    • (2001) J Clin Invest , vol.107 , pp. 909-916
    • Waaga, A.M.1    Gasser, M.2    Kist-Van Holthe, J.E.3
  • 11
    • 0030879985 scopus 로고    scopus 로고
    • Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction
    • VELLA JP, SPADAFORA-FERREIRA M, MURPHY B, et al: Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction. Transplantation 27:795-800, 1997
    • (1997) Transplantation , vol.27 , pp. 795-800
    • Vella, J.P.1    Spadafora-Ferreira, M.2    Murphy, B.3
  • 13
    • 0028275790 scopus 로고
    • Morphologic features of chronic rejection in kidney and less commonly transplanted organs
    • SIBLEY RK: Morphologic features of chronic rejection in kidney and less commonly transplanted organs. Clin Transplant 8:293-298, 1994
    • (1994) Clin Transplant , vol.8 , pp. 293-298
    • Sibley, R.K.1
  • 14
    • 0032892048 scopus 로고    scopus 로고
    • Apoptosis and expression of cytotoxic T lymphocyte effector molecules in renal allograft
    • OLIVE C, CHEUNG C, FALK MC: Apoptosis and expression of cytotoxic T lymphocyte effector molecules in renal allograft. Transplant Immunol 7:27-36, 1999
    • (1999) Transplant Immunol , vol.7 , pp. 27-36
    • Olive, C.1    Cheung, C.2    Falk, M.C.3
  • 15
    • 0030334109 scopus 로고    scopus 로고
    • Interstitial mononuclear cell infiltrates in chronic rejection of the kidney and correlation with peripheral blood
    • JEONG HJ, HONG SW, KIM YS, et al: Interstitial mononuclear cell infiltrates in chronic rejection of the kidney and correlation with peripheral blood. J Korean Med Sci 11:489-494, 1996
    • (1996) J Korean Med Sci , vol.11 , pp. 489-494
    • Jeong, H.J.1    Hong, S.W.2    Kim, Y.S.3
  • 16
    • 0029948767 scopus 로고    scopus 로고
    • The intragraft gene activation of markers reflecting T-cell-activation and -cytotoxicity analyzed by quantitative RT-PCR in renal transplantation
    • STREHLAU J, PAVLAKIS M, LIPMAN M, et al: The intragraft gene activation of markers reflecting T-cell-activation and -cytotoxicity analyzed by quantitative RT-PCR in renal transplantation. Clin Nephrol 46:30-33, 1996
    • (1996) Clin Nephrol , vol.46 , pp. 30-33
    • Strehlau, J.1    Pavlakis, M.2    Lipman, M.3
  • 17
    • 0026521361 scopus 로고
    • Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance
    • KIRK AD, IBRAHIM MA, BOLLINGER RR, et al: Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance. Transplantation 53:329-338, 1992
    • (1992) Transplantation , vol.53 , pp. 329-338
    • Kirk, A.D.1    Ibrahim, M.A.2    Bollinger, R.R.3
  • 18
    • 0028943870 scopus 로고
    • Design, synthesis, and structure activity relationship of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720
    • ADACHI K, KOHARA T, MISHINA T, FUJITA T: Design, synthesis, and structure activity relationship of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720. Bioorg Med Chem 5:853-856, 1995
    • (1995) Bioorg Med Chem , vol.5 , pp. 853-856
    • Adachi, K.1    Kohara, T.2    Mishina, T.3    Fujita, T.4
  • 19
    • 0034023906 scopus 로고    scopus 로고
    • Immunosuppressive agents in organ transplantation: Past, present, and future
    • HONG JC, KAHAN BD: Immunosuppressive agents in organ transplantation: Past, present, and future. Semin Nephrol 20:108-125, 2000
    • (2000) Semin Nephrol , vol.20 , pp. 108-125
    • Hong, J.C.1    Kahan, B.D.2
  • 20
    • 0034257077 scopus 로고    scopus 로고
    • The significance of timing of FTY720 administration on the immunosuppressive effect to prolong rat skin allograft survival
    • YANAGAWA Y, HOSHINO Y, CHIBA K: The significance of timing of FTY720 administration on the immunosuppressive effect to prolong rat skin allograft survival. Int J Immunopharmacol 22:597-602, 2000
    • (2000) Int J Immunopharmacol , vol.22 , pp. 597-602
    • Yanagawa, Y.1    Hoshino, Y.2    Chiba, K.3
  • 21
    • 0032103938 scopus 로고    scopus 로고
    • FTY720, a novel immunosuppressant, induces sequestration circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival decreasing T cell infiltraiton into grafts but not cytokine production in vivo
    • YANAGAWA Y, SUGAHARA K, KATAOKA H, et al: FTY720, a novel immunosuppressant, induces sequestration circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival decreasing T cell infiltraiton into grafts but not cytokine production in vivo. J Immunol 160:5493-5496, 1998
    • (1998) J Immunol , vol.160 , pp. 5493-5496
    • Yanagawa, Y.1    Sugahara, K.2    Kataoka, H.3
  • 22
    • 17744376466 scopus 로고    scopus 로고
    • Long-term graft acceptance in rat heart transplantation by gene transfection combined with FTY720 treatment
    • OHBA M, LI XK, KITA Y, et al: Long-term graft acceptance in rat heart transplantation by gene transfection combined with FTY720 treatment. World J Surg 25:391-397, 2001
    • (2001) World J Surg , vol.25 , pp. 391-397
    • Ohba, M.1    Li, X.K.2    Kita, Y.3
  • 23
    • 0035114740 scopus 로고    scopus 로고
    • Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720
    • LI XK, TAMURA A, FUJINO M, et al: Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720. Clin Exp Immunol 123:331-339, 2000
    • (2000) Clin Exp Immunol , vol.123 , pp. 331-339
    • Li, X.K.1    Tamura, A.2    Fujino, M.3
  • 24
    • 0034719352 scopus 로고    scopus 로고
    • Prolongation of canine liver allograft survival by a novel immuosuppressant, FTY720
    • FURUKAWA H, SUZUKI T, JIN MB, et al: Prolongation of canine liver allograft survival by a novel immuosuppressant, FTY720. Transplantation 69:235-241, 2000
    • (2000) Transplantation , vol.69 , pp. 235-241
    • Furukawa, H.1    Suzuki, T.2    Jin, M.B.3
  • 25
    • 0000220111 scopus 로고    scopus 로고
    • FTY720A mediates reduction of lynmphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism
    • BOHLER T, WAISER J, SCHUTZ M, et al: FTY720A mediates reduction of lynmphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism. Transplant Int 13:S311-S313, 2000
    • (2000) Transplant Int , vol.13
    • Bohler, T.1    Waiser, J.2    Schutz, M.3
  • 26
    • 0033668231 scopus 로고    scopus 로고
    • Effect of a novel immunosuppressant, FTY720, on allograft survival after renal transplant in rats
    • UEDA H, TAKAHARA S, AZUMA H, et al: Effect of a novel immunosuppressant, FTY720, on allograft survival after renal transplant in rats. Eur Surg Res 32:279-283, 2000
    • (2000) Eur Surg Res , vol.32 , pp. 279-283
    • Ueda, H.1    Takahara, S.2    Azuma, H.3
  • 27
    • 0032724212 scopus 로고    scopus 로고
    • A short-course therapy with FTY720 prolongs allograft survival after canine kidney transplantation
    • OMURA T, SUZUKI T, SHIMAMURA T, et al: A short-course therapy with FTY720 prolongs allograft survival after canine kidney transplantation. Transplant Proc 31:2783-2784, 1999
    • (1999) Transplant Proc , vol.31 , pp. 2783-2784
    • Omura, T.1    Suzuki, T.2    Shimamura, T.3
  • 28
    • 0033833627 scopus 로고    scopus 로고
    • Tolerance induction with FTY720 and donor-specific blood transfusion: Discrepancy between heart transplantation and intestinal transplantation
    • KOSHIBA T, JI P, TANAKA K, et al: Tolerance induction with FTY720 and donor-specific blood transfusion: Discrepancy between heart transplantation and intestinal transplantation. Transplant Proc 32:1255-1257, 2000
    • (2000) Transplant Proc , vol.32 , pp. 1255-1257
    • Koshiba, T.1    Ji, P.2    Tanaka, K.3
  • 29
    • 0031791427 scopus 로고    scopus 로고
    • Immunosuppressive effect of FTY720 on rat pancreas allograft
    • SUZUKI K, KAZUI T, KAWABE A, et al: Immunosuppressive effect of FTY720 on rat pancreas allograft. Transplant Proc 30:3417-3418, 1998
    • (1998) Transplant Proc , vol.30 , pp. 3417-3418
    • Suzuki, K.1    Kazui, T.2    Kawabe, A.3
  • 30
    • 0035076872 scopus 로고    scopus 로고
    • FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation model
    • FU F, HU S, LI S, et al: FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation model. Transplant Proc 33:672-673, 2000
    • (2000) Transplant Proc , vol.33 , pp. 672-673
    • Fu, F.1    Hu, S.2    Li, S.3
  • 31
    • 0030805527 scopus 로고    scopus 로고
    • Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY720, in rat small bowel transplantation
    • MITSUSADA M, SUZUKI S, KOBAYASHI E, et al: Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY720, in rat small bowel transplantation. Transplant Int 10:343-349, 1997
    • (1997) Transplant Int , vol.10 , pp. 343-349
    • Mitsusada, M.1    Suzuki, S.2    Kobayashi, E.3
  • 32
    • 0030049234 scopus 로고    scopus 로고
    • A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation
    • SUZUKI S, ENOSAWA S, KAKEFUDA T, et al: A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation. Transplantation 61:200-205, 1996
    • (1996) Transplantation , vol.61 , pp. 200-205
    • Suzuki, S.1    Enosawa, S.2    Kakefuda, T.3
  • 33
    • 0035082902 scopus 로고    scopus 로고
    • Combined FTY720/cyclosporine a treatment promotes graft survival and lowers the peripheral lymphocyte count in DA Lewis heart and skin transplantation models
    • NIKOLOVA Z, HOF A, BAUMLIN Y, HOF RP: Combined FTY720/cyclosporine A treatment promotes graft survival and lowers the peripheral lymphocyte count in DA Lewis heart and skin transplantation models. Transplant Immunol 8:267-277, 2001
    • (2001) Transplant Immunol , vol.8 , pp. 267-277
    • Nikolova, Z.1    Hof, A.2    Baumlin, Y.3    Hof, R.P.4
  • 34
    • 0033025331 scopus 로고    scopus 로고
    • FTY720, a novel immunosuppressant, shows a synergistic effect in combination with FK506 in rat allograft models
    • HOSHINO Y, YANAGAWA Y, OHTSUKI M, et al: FTY720, a novel immunosuppressant, shows a synergistic effect in combination with FK506 in rat allograft models. Transplant Proc 31:224-1226, 1999
    • (1999) Transplant Proc , vol.31 , pp. 224-1226
    • Hoshino, Y.1    Yanagawa, Y.2    Ohtsuki, M.3
  • 35
    • 0033958095 scopus 로고    scopus 로고
    • Immunosuppressive therapy using FTY720 combined with tacrolimus in rat liver transplantation
    • TAMURA A, LI XK, FUNESHIMA N, et al: Immunosuppressive therapy using FTY720 combined with tacrolimus in rat liver transplantation. Surgery 127:47-54, 2000
    • (2000) Surgery , vol.127 , pp. 47-54
    • Tamura, A.1    Li, X.K.2    Funeshima, N.3
  • 36
    • 0343819994 scopus 로고    scopus 로고
    • FTYS720 blocks allograft rejection by homing of lymphocyte in vivo
    • YUZAWA K, STEPHKOWSKI SM, WANG M, KAHAN BD: FTYS720 blocks allograft rejection by homing of lymphocyte in vivo. Transplant Proc 32:269, 2000
    • (2000) Transplant Proc , vol.32 , pp. 269
    • Yuzawa, K.1    Stephkowski, S.M.2    Wang, M.3    Kahan, B.D.4
  • 37
    • 0028676662 scopus 로고
    • Host leukocytes and their products in chronic kidney allograft rejection in rats
    • AZUMA H, HEEMANN U, TULLIUS SG, TILNEY NL: Host leukocytes and their products in chronic kidney allograft rejection in rats. Transplant Int 7:S325-S327, 1994
    • (1994) Transplant Int , vol.7
    • Azuma, H.1    Heemann, U.2    Tullius, S.G.3    Tilney, N.L.4
  • 38
    • 0032910625 scopus 로고    scopus 로고
    • The Banff 97 working classification of renal allograft pathology
    • RACUSEN LC, SOLEZ K, COLVIN RB, et al: The Banff 97 working classification of renal allograft pathology. Kidney Int 55:713-723, 1999
    • (1999) Kidney Int , vol.55 , pp. 713-723
    • Racusen, L.C.1    Solez, K.2    Colvin, R.B.3
  • 39
    • 0035964621 scopus 로고    scopus 로고
    • Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: An active mode of immune evasion in colon cancer
    • SONG E, CHEN J, OUYANG N, et al: Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: An active mode of immune evasion in colon cancer. Br J Cancer 85:1047-1054, 2001
    • (2001) Br J Cancer , vol.85 , pp. 1047-1054
    • Song, E.1    Chen, J.2    Ouyang, N.3
  • 40
    • 0034773379 scopus 로고    scopus 로고
    • Antiandrogens ameliorate chronic allograft nephropathy
    • ANTUS B, YAO Y, LIU S, et al: Antiandrogens ameliorate chronic allograft nephropathy. Kidney Int 60:1955-1963, 2001
    • (2001) Kidney Int , vol.60 , pp. 1955-1963
    • Antus, B.1    Yao, Y.2    Liu, S.3
  • 41
    • 0034055332 scopus 로고    scopus 로고
    • SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts
    • VIKLICKY O, ZOU H, MULLER V, et al: SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts. Transplantation 69:497-502, 2000
    • (2000) Transplantation , vol.69 , pp. 497-502
    • Viklicky, O.1    Zou, H.2    Muller, V.3
  • 42
    • 0029115699 scopus 로고
    • Influence of intrarenal deposits of ciclosporin a on acute renal transplant rejection
    • GOMEZ-MORALES M, BUSTOS M, MONTES A, et al: Influence of intrarenal deposits of ciclosporin A on acute renal transplant rejection. Nephron 70:402-409, 1995
    • (1995) Nephron , vol.70 , pp. 402-409
    • Gomez-Morales, M.1    Bustos, M.2    Montes, A.3
  • 43
    • 0031446586 scopus 로고    scopus 로고
    • Impact of new immunosuppressive agents on late graft outcome
    • VANRENTERGHEM YF: Impact of new immunosuppressive agents on late graft outcome. Kidney Int 52(Suppl 63):S81-S83, 1997
    • (1997) Kidney Int , vol.52 , Issue.63 SUPPL.
    • Vanrenterghem, Y.F.1
  • 44
    • 0031000670 scopus 로고    scopus 로고
    • Molecular analyses of human renal allografts: Differential intragraft gene expression during rejection
    • SUTHANTHIRAN M: Molecular analyses of human renal allografts: Differential intragraft gene expression during rejection. Kidney Int 52(Suppl 58):S15-S52, 1997
    • (1997) Kidney Int , vol.52 , Issue.58 SUPPL.
    • Suthanthiran, M.1
  • 45
    • 0029086366 scopus 로고
    • Sequential cytokine dynamics in chronic rejection of rat renal allograft: Roles for cytokines RANTES and MCP-1
    • NADEAU KC, AZUMA H, TILNEY NL: Sequential cytokine dynamics in chronic rejection of rat renal allograft: Roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci USA 92:8729-8733, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8729-8733
    • Nadeau, K.C.1    Azuma, H.2    Tilney, N.L.3
  • 46
    • 0035870788 scopus 로고    scopus 로고
    • Involvement of platelet-derived growth factor and histocompatibility of DRB 1 in chronic renal allograft nephrophathy
    • YAMADA K, HATAKEYAMA E, SAKAMAKI T, et al: Involvement of platelet-derived growth factor and histocompatibility of DRB 1 in chronic renal allograft nephrophathy. Transplantation 71:936-941, 2001
    • (2001) Transplantation , vol.71 , pp. 936-941
    • Yamada, K.1    Hatakeyama, E.2    Sakamaki, T.3
  • 47
    • 12644252937 scopus 로고    scopus 로고
    • T-cell interactions with extracellular matrix proteins and endothelium in chronic renal allograft rejection
    • KORCZAK-KOWALSKA G, NOWACZYK M, STEPIEN-SOPNIEWSKA B, et al: T-cell interactions with extracellular matrix proteins and endothelium in chronic renal allograft rejection. Transplant Proc 29:1057-1059, 1997
    • (1997) Transplant Proc , vol.29 , pp. 1057-1059
    • Korczak-Kowalska, G.1    Nowaczyk, M.2    Stepien-Sopniewska, B.3
  • 48
    • 0026729563 scopus 로고    scopus 로고
    • Heart grafts in murine systems: The differential activation of Th2-like effectors in peripheral tolerance
    • TAKEUCHI T, LOWRY RP, KONIECZNY B: Heart grafts in murine systems: The differential activation of Th2-like effectors in peripheral tolerance. Transplantation 53:1281-1294
    • Transplantation , vol.53 , pp. 1281-1294
    • Takeuchi, T.1    Lowry, R.P.2    Konieczny, B.3
  • 49
    • 0028895076 scopus 로고
    • IL-10 immunosuppression in transplantation
    • BROMBERG JS: IL-10 immunosuppression in transplantation. Curr Opin Immunol 7:639-643, 1995
    • (1995) Curr Opin Immunol , vol.7 , pp. 639-643
    • Bromberg, J.S.1
  • 50
    • 0024840085 scopus 로고
    • Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth in cultured rat liver fat-storing cells
    • PINZANI M, GESUALDO L, SABBAH GM, ABBOUND HE: Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth in cultured rat liver fat-storing cells. J Clin Invest 84:1786-1793, 1989
    • (1989) J Clin Invest , vol.84 , pp. 1786-1793
    • Pinzani, M.1    Gesualdo, L.2    Sabbah, G.M.3    Abbound, H.E.4
  • 51
    • 0026308617 scopus 로고
    • Differential proliferation of rat lung fibroblasts induced by the platelet-derived growth factor-AA, -AB, and BB isoforms secreted by rat alveolar macrophages
    • BONNER JC, OSORNIO-VARGAS AR, BADGETT A, BRODY AR: Differential proliferation of rat lung fibroblasts induced by the platelet-derived growth factor-AA, -AB, and BB isoforms secreted by rat alveolar macrophages. Am J Respir Cell Mol Biol 5:539-549, 1991
    • (1991) Am J Respir Cell Mol Biol , vol.5 , pp. 539-549
    • Bonner, J.C.1    Osornio-Vargas, A.R.2    Badgett, A.3    Brody, A.R.4
  • 52
    • 0001184102 scopus 로고    scopus 로고
    • Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat
    • SZABO A, LUTZ J, SCHLEIMER K, et al: Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat. Kidney Int 57:982-991, 2000
    • (2000) Kidney Int , vol.57 , pp. 982-991
    • Szabo, A.1    Lutz, J.2    Schleimer, K.3
  • 53
    • 0029812735 scopus 로고    scopus 로고
    • Induction of lymphocyte apoptosis and üprolongation of allograft survival by FTY720
    • SUZUKI S, LI XK, SHINOMIYA T, et al: Induction of lymphocyte apoptosis and üprolongation of allograft survival by FTY720. Transplant Proc 28:2049-2050, 1996
    • (1996) Transplant Proc , vol.28 , pp. 2049-2050
    • Suzuki, S.1    Li, X.K.2    Shinomiya, T.3
  • 54
    • 0029857032 scopus 로고    scopus 로고
    • A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes
    • SUZUKI S, LI XK, ENOSAWA S, SHINOMIYA T: A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes. Immunology 89:518-523, 1996
    • (1996) Immunology , vol.89 , pp. 518-523
    • Suzuki, S.1    Li, X.K.2    Enosawa, S.3    Shinomiya, T.4
  • 55
    • 0034665512 scopus 로고    scopus 로고
    • Immunosuppressant FTY720 induces apoptosis by direct induction of üpermeability transition and release of cytochrome c from mitochondria
    • NAGAHARA Y, IKEKITA M, SHINOMIYA T: Immunosuppressant FTY720 induces apoptosis by direct induction of üpermeability transition and release of cytochrome c from mitochondria. J Immunol 165:3250-3259, 2000
    • (2000) J Immunol , vol.165 , pp. 3250-3259
    • Nagahara, Y.1    Ikekita, M.2    Shinomiya, T.3
  • 56
    • 0032525049 scopus 로고    scopus 로고
    • FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
    • CHIBA K, YANAGAWA Y, MASUBUCHI Y, et al: FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J Immunol 160:5037-5044, 1998
    • (1998) J Immunol , vol.160 , pp. 5037-5044
    • Chiba, K.1    Yanagawa, Y.2    Masubuchi, Y.3
  • 57
    • 0032980920 scopus 로고    scopus 로고
    • Analysis of the mode of action of a novel immunosuppressant FTY720 in mice
    • LUO ZJ, TANAKA T, KIMURA F, MIYAAKA M: Analysis of the mode of action of a novel immunosuppressant FTY720 in mice. Immunopharmacology 41:199-207, 1999
    • (1999) Immunopharmacology , vol.41 , pp. 199-207
    • Luo, Z.J.1    Tanaka, T.2    Kimura, F.3    Miyaaka, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.