메뉴 건너뛰기




Volumn 15, Issue 4, 2004, Pages 207-222

Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: Role of conventional and novel PKC isoforms

Author keywords

CD4; CXCR4; HIV; PKC; Prostratin

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; ISOPROTEIN; MEMBRANE PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTRATIN; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

EID: 4344651661     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020401500404     Document Type: Article
Times cited : (48)

References (54)
  • 1
    • 0033625869 scopus 로고    scopus 로고
    • Protein kinase Ctheta: A new essential superstar on the T-cell stage
    • Altman A, Isakov N & Baier G (2000) Protein kinase Ctheta: a new essential superstar on the T-cell stage. Immunology Today 21:567-573.
    • (2000) Immunology Today , vol.21 , pp. 567-573
    • Altman, A.1    Isakov, N.2    Baier, G.3
  • 2
    • 0030812438 scopus 로고    scopus 로고
    • Molecular mechanism of desensitization of the chemokine receptor CCR-5: Receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor
    • Aramori I, Ferguson SS, Bieniasz PD, Zhang J, Cullen B & Cullen MG (1997) Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor. EMBO Journal 16:4606-4616.
    • (1997) EMBO Journal , vol.16 , pp. 4606-4616
    • Aramori, I.1    Ferguson, S.S.2    Bieniasz, P.D.3    Zhang, J.4    Cullen, B.5    Cullen, M.G.6
  • 5
    • 0035037684 scopus 로고    scopus 로고
    • Membrane lipid microdomains and the role of PKCtheta in T cell activation
    • Bi K & Altman A (2001) Membrane lipid microdomains and the role of PKCtheta in T cell activation. Seminar Immunology 13:139-146.
    • (2001) Seminar Immunology , vol.13 , pp. 139-146
    • Bi, K.1    Altman, A.2
  • 6
    • 0041743235 scopus 로고    scopus 로고
    • Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate
    • Bocklandt S, Blumberg PM & Hamer DH (2003) Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate. Antiviral Research 59:89-98.
    • (2003) Antiviral Research , vol.59 , pp. 89-98
    • Bocklandt, S.1    Blumberg, P.M.2    Hamer, D.H.3
  • 10
    • 0027104825 scopus 로고
    • The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation
    • Clemens MJ, Trayner I & Menaya J (1992) The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation. Journal of Cellular Science 103:881-887.
    • (1992) Journal of Cellular Science , vol.103 , pp. 881-887
    • Clemens, M.J.1    Trayner, I.2    Menaya, J.3
  • 12
    • 0038204321 scopus 로고    scopus 로고
    • Evaluation and management of metabolic and coagulative disorders in HIV-infected patients receiving highly active antiretroviral therapy
    • Fantoni M, Del Borgo C & Autore C (2003) Evaluation and management of metabolic and coagulative disorders in HIV-infected patients receiving highly active antiretroviral therapy AIDS 17 (Suppl 1):S162-169.
    • (2003) AIDS , vol.17 , Issue.SUPPL. 1
    • Fantoni, M.1    Del Borgo, C.2    Autore, C.3
  • 14
    • 0023881037 scopus 로고
    • Rapid and reversible modulation of T4 (CD4) on monocytoid cells by phorbol myristate acetate: Effect on HIV susceptibility
    • Firestein GS, Reifler D, Richman D & Gruber HE (1988) Rapid and reversible modulation of T4 (CD4) on monocytoid cells by phorbol myristate acetate: effect on HIV susceptibility. Cellular Immunology 113:63-69.
    • (1988) Cellular Immunology , vol.113 , pp. 63-69
    • Firestein, G.S.1    Reifler, D.2    Richman, D.3    Gruber, H.E.4
  • 16
    • 0032567335 scopus 로고    scopus 로고
    • A novel mechanism of CD4 down-modulation induced by monosialoganglioside GM3. Involvement of serine phosphorylation and protein kinase c delta translocation
    • Garofalo T, Sorice M, Misasi R, Cinque B, Giammatteo M, Pontieri GM, Cifone MG & Pavan A (1998) A novel mechanism of CD4 down-modulation induced by monosialoganglioside GM3. Involvement of serine phosphorylation and protein kinase c delta translocation. Journal of Biological Chemistry 273:35153-35160.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 35153-35160
    • Garofalo, T.1    Sorice, M.2    Misasi, R.3    Cinque, B.4    Giammatteo, M.5    Pontieri, G.M.6    Cifone, M.G.7    Pavan, A.8
  • 17
    • 0031023704 scopus 로고    scopus 로고
    • Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV)
    • Gulakowski RJ, McMahon JB, Buckheit RW Jr, Gustafson KR & Boyd MR (1997) Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV). Antiviral Research 33:87-97.
    • (1997) Antiviral Research , vol.33 , pp. 87-97
    • Gulakowski, R.J.1    McMahon, J.B.2    Buckheit Jr., R.W.3    Gustafson, K.R.4    Boyd, M.R.5
  • 20
    • 0037241329 scopus 로고    scopus 로고
    • Emerging drug toxicities of highly active anti-retroviral therapy for human immunodeficiency virus (HIV) infection
    • Heath KV, Montaner JS, Bondy G, Singer J, O'Shaughnessy MV & Hogg RS (2003) Emerging drug toxicities of highly active anti-retroviral therapy for human immunodeficiency virus (HIV) infection. Current Drug Targets 4:13-22.
    • (2003) Current Drug Targets , vol.4 , pp. 13-22
    • Heath, K.V.1    Montaner, J.S.2    Bondy, G.3    Singer, J.4    O'Shaughnessy, M.V.5    Hogg, R.S.6
  • 21
    • 0025078379 scopus 로고
    • Selective post-transcriptional down-regulation of protein kinase C isoenzymes in leukemic T cells chronically treated with phorbol ester
    • Isakov N, McMahon P & Altman A (1990) Selective post-transcriptional down-regulation of protein kinase C isoenzymes in leukemic T cells chronically treated with phorbol ester. Journal of Biological Chemistry 265:2091-2097.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 2091-2097
    • Isakov, N.1    McMahon, P.2    Altman, A.3
  • 22
    • 0025004457 scopus 로고
    • Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells
    • Kinter AL, Poli G, Maury W, Folks TM & Fauci AS (1990) Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells. Journal of Virology 64:4306-4312.
    • (1990) Journal of Virology , vol.64 , pp. 4306-4312
    • Kinter, A.L.1    Poli, G.2    Maury, W.3    Folks, T.M.4    Fauci, A.S.5
  • 23
    • 0036315848 scopus 로고    scopus 로고
    • Effects of prostratin on T-cell activation and human immunodeficiency virus latency
    • Korin YD, Brooks DG, Brown S, Korotzer A & Zack JA (2002) Effects of prostratin on T-cell activation and human immunodeficiency virus latency. Journal of Virology 76:8118-8123.
    • (2002) Journal of Virology , vol.76 , pp. 8118-8123
    • Korin, Y.D.1    Brooks, D.G.2    Brown, S.3    Korotzer, A.4    Zack, J.A.5
  • 24
    • 0035892120 scopus 로고    scopus 로고
    • Prostratin: Activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART
    • Kulkosky J, Culnan DM, Roman J, Dornadula G, Schnell M, Boyd MR & Pomerantz RJ (2001) Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART. Blood 98:3006-3015.
    • (2001) Blood , vol.98 , pp. 3006-3015
    • Kulkosky, J.1    Culnan, D.M.2    Roman, J.3    Dornadula, G.4    Schnell, M.5    Boyd, M.R.6    Pomerantz, R.J.7
  • 26
    • 0025129069 scopus 로고
    • Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: Blockade by protein kinase inhibitors and relationship to tat-directed trans-activation
    • Laurence J, Sikder SK, Jhaveri S & Salmon JE (1990) Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: blockade by protein kinase inhibitors and relationship to tat-directed trans-activation. Biochemical & Biophysical Research Communications 166:349-357.
    • (1990) Biochemical & Biophysical Research Communications , vol.166 , pp. 349-357
    • Laurence, J.1    Sikder, S.K.2    Jhaveri, S.3    Salmon, J.E.4
  • 27
    • 0034031401 scopus 로고    scopus 로고
    • Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta
    • Lin X, O'Mahony A, Mu Y, Geleziunas R & Greene WC (2000) Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Molecular & Cellular Biology 20:2933-2940.
    • (2000) Molecular & Cellular Biology , vol.20 , pp. 2933-2940
    • Lin, X.1    O'Mahony, A.2    Mu, Y.3    Geleziunas, R.4    Greene, W.C.5
  • 28
    • 0031786125 scopus 로고    scopus 로고
    • The sevenfold way of PKC regulation
    • Liu WS & Heckman CA (1998) The sevenfold way of PKC regulation. Cellular Signalling 10:529-542.
    • (1998) Cellular Signalling , vol.10 , pp. 529-542
    • Liu, W.S.1    Heckman, C.A.2
  • 29
    • 0030614819 scopus 로고    scopus 로고
    • The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
    • Mangasarian A, Foti M, Aiken C, Chin D, Carpentier JL & Trono D (1997) The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67-77.
    • (1997) Immunity , vol.6 , pp. 67-77
    • Mangasarian, A.1    Foti, M.2    Aiken, C.3    Chin, D.4    Carpentier, J.L.5    Trono, D.6
  • 30
    • 0027050407 scopus 로고
    • Phorbol ester reduces constitutive nuclear NF kappa B and inhibits HIV-1 production in mature human monocytic cells
    • Mufson RA, Myers C, Turpin JA & Meltzer M (1992) Phorbol ester reduces constitutive nuclear NF kappa B and inhibits HIV-1 production in mature human monocytic cells. Journal of Leukocyte Biology 52:637-644.
    • (1992) Journal of Leukocyte Biology , vol.52 , pp. 637-644
    • Mufson, R.A.1    Myers, C.2    Turpin, J.A.3    Meltzer, M.4
  • 31
    • 0033553484 scopus 로고    scopus 로고
    • Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms
    • Parolini I, Topa S, Sorice M, Pace A, Ceddia P, Montesoro E, Pavan A, Lisanti MP, Peschle C & Sargiacomo M (1999) Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms. Journal of Biological Chemistry 274:14176-14187.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 14176-14187
    • Parolini, I.1    Topa, S.2    Sorice, M.3    Pace, A.4    Ceddia, P.5    Montesoro, E.6    Pavan, A.7    Lisanti, M.P.8    Peschle, C.9    Sargiacomo, M.10
  • 33
    • 0024789208 scopus 로고
    • Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells
    • Pelchen-Matthews A, Armes JE & Marsh M (1989) Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells. EMBO Journal 8:3641-3649
    • (1989) EMBO Journal , vol.8 , pp. 3641-3649
    • Pelchen-Matthews, A.1    Armes, J.E.2    Marsh, M.3
  • 34
    • 0026506657 scopus 로고
    • The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits
    • Pelchen-Matthews A, Boulet I, Littman DR, Fagard R & Marsh M (1992) The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits. Journal of Cellular Biology 117:279-290.
    • (1992) Journal of Cellular Biology , vol.117 , pp. 279-290
    • Pelchen-Matthews, A.1    Boulet, I.2    Littman, D.R.3    Fagard, R.4    Marsh, M.5
  • 35
    • 0027321454 scopus 로고
    • Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting
    • Pelchen-Matthews A, Parsons IJ & Marsh M (1993) Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting. Journal of Experimental Medicine 178:1209-1222.
    • (1993) Journal of Experimental Medicine , vol.178 , pp. 1209-1222
    • Pelchen-Matthews, A.1    Parsons, I.J.2    Marsh, M.3
  • 37
    • 0028200761 scopus 로고
    • Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4
    • Rhee SS & Marsh JW (1994) Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. Journal of Virology 68:5156-5163.
    • (1994) Journal of Virology , vol.68 , pp. 5156-5163
    • Rhee, S.S.1    Marsh, J.W.2
  • 38
    • 0029980243 scopus 로고    scopus 로고
    • Activating protein-1 cooperates with phorbol ester activation signals to increase HIV-1 expression
    • Roebuck KA, Gu DS & Kagnoff MF (1996) Activating protein-1 cooperates with phorbol ester activation signals to increase HIV-1 expression. AIDS 10:819-826.
    • (1996) AIDS , vol.10 , pp. 819-826
    • Roebuck, K.A.1    Gu, D.S.2    Kagnoff, M.F.3
  • 39
    • 0025089942 scopus 로고
    • Structural features of the cytoplasmic region of CD4 required for internalization
    • Shin J, Doyle C, Yang Z, Kappes D & Strominger JL (1990) Structural features of the cytoplasmic region of CD4 required for internalization. EMBO Journal 9:425-434.
    • (1990) EMBO Journal , vol.9 , pp. 425-434
    • Shin, J.1    Doyle, C.2    Yang, Z.3    Kappes, D.4    Strominger, J.L.5
  • 44
    • 0024431785 scopus 로고
    • Phorbol esters stimulate macropinocytosis and solute flow through macrophages
    • Swanson JA (1989) Phorbol esters stimulate macropinocytosis and solute flow through macrophages. Journal of Cell Science 94:135-142.
    • (1989) Journal of Cell Science , vol.94 , pp. 135-142
    • Swanson, J.A.1
  • 45
    • 0026049420 scopus 로고
    • Prostratin, a nonpromoting phorbol ester, inhibits induction by phorbol 12-myristate 13-acetate of ornithine decarboxylase, edema, and hyperplasia in CD-1 mouse skin
    • Szallasi Z & Blumberg PM (1991) Prostratin, a nonpromoting phorbol ester, inhibits induction by phorbol 12-myristate 13-acetate of ornithine decarboxylase, edema, and hyperplasia in CD-1 mouse skin. Cancer Research 51:5355-5360.
    • (1991) Cancer Research , vol.51 , pp. 5355-5360
    • Szallasi, Z.1    Blumberg, P.M.2
  • 46
    • 0026476731 scopus 로고
    • Non-promoting 12-deoxyphorbol 13-esters as potent inhibitors of phorbol 12-myristate 13-acetate-induced acute and chronic biological responses in CD-1 mouse skin
    • Szallasi Z, Krausz KW & Blumberg PM (1992) Non-promoting 12-deoxyphorbol 13-esters as potent inhibitors of phorbol 12-myristate 13-acetate-induced acute and chronic biological responses in CD-1 mouse skin. Carcinogenesis 13:2161-2167.
    • (1992) Carcinogenesis , vol.13 , pp. 2161-2167
    • Szallasi, Z.1    Krausz, K.W.2    Blumberg, P.M.3
  • 47
    • 0027212503 scopus 로고
    • Nonpromoting 12-deoxyphorbol 13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1 mouse skin
    • Szallasi Z, Krsmanovic L & Blumberg PM (1993) Nonpromoting 12-deoxyphorbol 13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1 mouse skin. Cancer Research 53:2507-2512.
    • (1993) Cancer Research , vol.53 , pp. 2507-2512
    • Szallasi, Z.1    Krsmanovic, L.2    Blumberg, P.M.3
  • 48
    • 0027256455 scopus 로고
    • Regulation of protein kinase C isoform proteins in phorbol ester-stimulated Jurkat T lymphoma cells
    • Tsutsumi A, Kubo M, Fujii H, Freire-Moar J, Turck CW & Ransom JT (1993) Regulation of protein kinase C isoform proteins in phorbol ester-stimulated Jurkat T lymphoma cells. Journal of Immunology 150:1746-1754.
    • (1993) Journal of Immunology , vol.150 , pp. 1746-1754
    • Tsutsumi, A.1    Kubo, M.2    Fujii, H.3    Freire-Moar, J.4    Turck, C.W.5    Ransom, J.T.6
  • 50
    • 0026452726 scopus 로고
    • Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4
    • Willey RL, Maldarelli F, Martin MA & Strebel K (1992) Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. Journal of Virology 66:7193-200.
    • (1992) Journal of Virology , vol.66 , pp. 7193-7200
    • Willey, R.L.1    Maldarelli, F.2    Martin, M.A.3    Strebel, K.4
  • 53
    • 0017655069 scopus 로고
    • New tigliane and daphnane derivatives from Pimeleaprostrata and Pimelea simplex
    • Zayed S, Hafez A, Adolf W & Hecker E (1977) New tigliane and daphnane derivatives from Pimeleaprostrata and Pimelea simplex. Experientia 33:1554-1555.
    • (1977) Experientia , vol.33 , pp. 1554-1555
    • Zayed, S.1    Hafez, A.2    Adolf, W.3    Hecker, E.4
  • 54
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey R, Nagy D, Mandel RJ, Naldini L & Trono D (1997) Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnology 15:871-875.
    • (1997) Nature Biotechnology , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.