Emerging drug toxicities of highly active antiretroviral therapy for human immunodeficiency virus (HIV) infection

Current Drug Targets

Volumn 4, Issue 1, 2003, Pages 13-22

  Heath, K V ^a   Montaner, J S G ^a   Bondy, G ^a   Singer, J ^a   O'Shaughnessy, M V ^a   Hogg, R S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; ANTIRETROVIRUS AGENT; CERIVASTATIN; DIDANOSINE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; ORAL ANTIDIABETIC AGENT; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

BONE DENSITY; BONE MINERAL; BONE NECROSIS; CLINICAL PRACTICE; DRUG EFFICACY; DRUG WITHDRAWAL; DYSLIPIDEMIA; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERLACTATEMIA; LACTIC ACIDOSIS; LIPOATROPHY; LIPODYSTROPHY; LIPOHYPERTROPHY; METABOLIC BONE DISEASE; METABOLIC DISORDER; OSTEOPENIA; OSTEOPOROSIS; PATHOGENESIS; PATIENT COMPLIANCE; REVIEW; TISSUE SPECIFICITY;

ACIDOSIS, LACTIC; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BONE DISEASES, METABOLIC; DNA, MITOCHONDRIAL; HIV INFECTIONS; HUMANS; LACTIC ACID; LIPODYSTROPHY; METABOLIC DISEASES;

EID: 0037241329     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450033347109     Document Type: Review

References (108)

1. Michelet, C.; Arvieux, C.; Francois, C.; Besnien, J.M.; Rogers, J.P.; Breux, J.P.; Sovala, F.; Allavena, C.; Raffi, F. (1998) AIDS 12, 1815-1822.
2. Hogg, R.S.; Heath, K.V.; Yip, B.; Schecter, M.T.; Craib, K.J.P.; O'Shaughnessy, M.V.; Montaner, J.S. (1998) JAMA 279, 450-454.
3. Palella, F.J. Jr.; Delany, K.M.; Moorman, A.C.; Loveless M.O.; Fuhre, J.; Satten, G.A.; Aschman, O.J. (1998) N. Engl. J. Med. 338, 853-860.
4. Carr, A.; Samaras, K.; Chisholm, D.J.; Cooper, D.A. (1998) Lancet 351, 1881-1883.
5. Miller, K.D.; Jones, E.; Yanovski, J.A.; Shankar, R.; Feurstein, I.; Falloon, J. (1998) Lancet 351(9106), 871-5.
6. Carr, A.; Samaras, K.; Burton, S.; Law, M.; Freund, J.; Chisholm, D.J.; Cooper, D.A. (1998) AIDS 12(7), F51-F58.
7. Thiébaut, R.; Daucourt, V.; Malvy, D.; et al. (1999) 1st International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, San Diego, California [abstract 17].
8. Wali, R.K.; Hefort, O.; Michl, G.M.; Demant, T.; Jager, H.; Dieterte, C.; Bogner, J.R.; Landgraf, R.; Goebel, F.D. (1998) AIDS 12, F167-F173.
9. Carr, A.; Samaras, K.; Thorisdottir, A.; Kaufman, E.R.; Chisholm, D.J.; Cooper, D.A (1999) Lancet 353, 2093-99.
10. Dube, M.P.; Johnson, D.L.; Currier, J.S.; Leedom, J.M. (1997) Lancet 350, 713-714.
11. Safrin, S. and Grunfeld, C. (1999) AIDS 13, 2493-2505.
12. Heath, K.V.; Hogg, R.S.; Chan, K.J.; Harris, M.; Montissori, V.; O'Shaughnessy, M.V. (2001) AIDS 15, 1-9.
13. Saint-Marc, T.; Partisani, M.; Poizot-Martin, I.; Rouviere, O.; Bruno, F.; Avellaneda, R.; Lang, J.; Gastaut, J.; Touraine, J. (2000) AIDS 14, 37-49.
14. Goebel, F.D.; Walli, R. (1999) [abstract 005]. Antiviral. Ther. 4 (suppl. 2), 13.
15. Rakotoambinina, B.; Medioni, J.; Rabian, C.; Jubault, V.; Jais, J.P.; Viard, J.P (2001) J. Acquir. Immune. Defic. Syndr. 27, 443-449.
16. van der Valk, M.; Gisolf, E.H.; Reiss, P., Wit, F.W.N.M.; Japour, A.; Weverling, G.J.; Danner, S.A.; on behalf of the Prometheus study group. (2000) AIDS 15, 847-855.
17. Martinez, E.; Mocroft, A.; Garcia-Viejo, M.A.; Perez-Cuevas, J.B.; Blanco, J.L.; Mallolas, J.; Bianchi, L.; Conget, I.; Blanch, J.; Phillips, A.; Gatell, J.M. (2001) Lancet 357, 592-98.
18. Goujard, C.; Boufassa, F.; Deveau, C.; Laskri, D.; Meyer, L. for the Primo Group. (2001) 8th Conference on Retroviruses and Opportunistic Infections [abstract 403].
19. Striker, R.; Conlin, D.; Marz, M.; Wiviott, L. (1998) ACID 27, 218-220.
20. Schindler, J.T.; Sponer, K.M.; Deker, C.F. (1998) Ann. Intern. Med. [Letter] 129, 164.
21. Virben, R. and Aquilna, C. (1998) AIDS 12, F37-F39.
22. Sullivan, A.K.; Feher, M.D.; Nelson, M.R.; Gazzard, B.G. (1998) AIDS [Letter] 12 (11), 1395-6.
23. Kotler, D.P.; Rosenbaum, K.; Wang, J.; Pierson, R.N. (1999) J. Acquir. Immun. Defic. Syndr. Human Retrovirol. 20, 228-237.
24. Thiebaut, R.; Daucourt, V.; Mercie, P.; Ekouevi, D.K.; Malvy, D.; Morlat, P.; Dupon, M.; Neau, D.; Farbos, S.; Marimoutou, C.; Dabis, F. (2000) ACID 31, 1482-1487.
25. Polo, R.; Verdejo, J.; Gonzalez-Munoz, M.; et al. (1999) 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California [abstract 1302].
26. Carr, A.; Samaras, K.; Thorisdottir, A.; Kaufman, E.R.; Chisholm, D.J.; Cooper, D.A. (1999) Lancet 353, 2093-9.
27. Saint-Marc, T.; Partisani, M.; Poizot-Martin, I.; Bruno, F.; Rouviere, O.; Lang, J.; Gastaut, J.; Touraine, J. (1999) AIDS 13, 1659-1667.
28. Bogner, J.R.; Vielhauer, V.; Beckman, R.A.; Michl, G.; Wille, L.; Salzberger, B.; Goebel, F.D. (2001) J. Acquir. Immun. Defic. Syndr. 27, 237-244.
29. Lichtenstein, K.A.; Ward, D.J.; Moorman, A.C.; Delaney, K.M.; Young, B.; Palella, F.J.; Rhodes, P.H.; Wood, K.C.; Holmberg, S.D. (2001) AIDS 15, 1389-1398.
30. Mallal, S.A.; John, M.; Moore, C.B.; James, I.R.; McKinnon, E.J. (2000) AIDS 14, 1309-1316.
31. Paparizos, V.A.; Kyriakis, K.P.; Botsis, C.; Papastamopoulos, V.; Hadjivassiliou, M.; Stavrianeas, N.G. (2000) AIDS [Letter] 14, 903-905.
32. Boufassa, F.; Dulioust, A.; Lascaux, A.S.; Meyer, L.; Bove, F.; Delfiraissy, J.F.; Sobel, A.; Goujard, C. (2001) HIV Clin. Trials 2, 339-345.
33. Knopp, R.H. (1999) N. Engl. J. Med. 341, 498-511.
34. Anderson, D.W. and Virmani, R. (1990) Human Pathology 21, 253-259.
35. Patel, R.C. and Frishman, W.H. (1997) Medical Clinics of North America 80, 1493-1512.
36. Baum, M.K. Shor-Posner, G.; Lai, S.; Zhang, G.; Lai, H.; Fletcher, M.A.; Sauberlich, H.; Page, J.B. (1997) J. Acquir. Immun. Defic. Syndr. 15, 370-374.
37. Constans, J.; Pellegrin, J.L.; Peuchant, E.; Dumon, M.F.; Pellegrin, I.; Sergeant, C.; Simonoff, M.; Boussard, G.; Barbeau, P.; Fleury, H. (1994) Eur. J. Clin. Invest. 24, 416-420.
38. Tabib, A.; Leroux, C.; Mornex, J.F.; Loire, R. (2000) Coron. Artery Dis. 11, 41-46.
39. Constans, J.; Marchand, J.M.; Conri, C.; Peuchant, E.; Seigneur, M.; Rispal, P.; Lasseur, C.; Pellegrin, J.L. (1995) Ann. Med. 27, 683-685.
40. Henry, K.; Melroe, H.; Huebsch, J.; Hermundson, J.; Levine, C.; Swensen, L.; Daley, J. (1998) Lancet 351, 1328.
41. Maggi, P.; Serio, G.; Epifani, G.; Fiorentino, G.; Saracino, A.; Fico, C.; Perilli, F.; Lillo, A.; Ferraro, S.; Gangiulo, M.; Chirianni, A.; Gioacchino, A.; Regina, G.; Pastore, G. (2000) AIDS 14, 123-128.
42. Depairon, M.; Chessex, S.; Sudre, P.; Rondondi, N.; Doser, N.; Chave, J.; Riesen, W.; Niced, P.; Darioli, R.; Telenti, A.; Mooser, V. (2001) AIDS 15, 329-334.
43. Stamler, J.; Wentworth, D.; Neaton, J.D. (1986) JAMA 256, 2823-28.
44. Howard, G.; Bergman, R.; Wagenknecht, L.E.; Haffner, S.M.; Savage, P.J.; Saad, M.F.; Laws, A.; D'Angostino, R.B. (1998) Ann. Epidemiol. 8, 358-369.
45. Hadigan, C.; Meigs, J.B.; Corcoran, C.; Rietschel, P.; Piecuch, S.; Basgoz, N.; Davis, B.; Sax, P.; Stanley, T.; Wilson, P.W.; D'Angostino, R.B.; Grinspoon, S. (2001) ACID 32, 130-139.
46. Holmberg, S.; Moorman, A.C.; Tong, T. et al. (2001) Program and abstracts of the 39th Annual Meeting of the Infectious Diseases Society of America, San Francisco [abstract 18].
47. Henry, K.; Melroe, H.; Heubesch, J.; Hermundson, J.; Levine, C.; Swensen, L.; Daley, J. (1998) Lancet 352, 1031-1032.
48. Ballantyne, C.M. (1998) Am. J. Med. 104, 33S-41S.
49. Moyle, G.J.; Lloyd, M.; Reynolds, B.; Baldwin, C.; Mandalia, S.; Gazzard, B.G. (2001) AIDS 15, 1503-1508.
50. Walli, R.K.; Michl, G.M.; Bogner, J.R.; Goebel, F.D. (1999) Program and Abstracts of the 6th Conference on retroviruses and Opportunistic Infections, Chicago, Illinois [abstract 673].
51. Saint-Marc, T. and Touraine, J.L. (1999) Program and Abstracts of the 6th Conference on retroviruses and Opportunistic Infections, Chicago, Illinois [abstract 672].
52. Arioglu, E.; Duncan-Morin, J.; Sebring, N.; Rother, K.I.; Gottlieb, N.; Lieberman, J.; Herion, D.; Kleiner, D.E.; Reynolds, J.; Premkumar, A.; Sumner, A.E.; Hoofnagle, J.; Reitman, M.L.; Taylor, S.I. (2000) Ann. Intern. Med. 133, 263-274.
53. Hadigan, C.; Corcoran, C.; Basgoz, N.; Davis, B.; Sax, P.; Grinspoon, S. (2000) JAMA 284, 472-477.
54. Derfronzo, R.A. (1999) Ann. Intern. Med 131, 281-303.
55. Roubenoff, R.; Weiss, L.; McDermott, A.; Heflin, T.; Clouties, G.J.; Wood, M.; Gorbach, S. (1999) AIDS 13, 1373-1375.
56. Strawford, A.; Barbieri, T.; Van Loan, M.; Parks, E.; Catlin, D.; Barton, N.; Neese, R.; Christiansen, M.; King, J.; Hellerstein, M.K. (1999) JAMA 281, 1282-1290.
57. Schambelan, M.; Mulligan, K.; Grunfeld, C.; Daar, E.S.; LaMarca, A.; Kotler, D.P.; Wang, J.; Bozette, S.A. (1996) Ann. Intern. Med 125, 873-882.
58. Torres, R. and Unger, K. (1999) 6th Conference on Retroviruses and Opportunistic Infections, Chicago, Illinois [abstract 675].
59. Chattha, G.; Arieff, A.I.; Cummings, C.; Tierney, L.M. (1993) Ann. Intern. Med. 11, 37-39.
60. Bissuel, F.; Bruneel, F.; Habersetzer, F.; Chassard, D.; Cotte, L.; Chevallier, M.; Bernuau, J.; Lucet, J.C. (1994) J. Intern. Med. 235, 367-371.
61. Lewis, W. and Dalakis, M.C. (1995) Nature Med 1, 417-421.
62. Sundar, K.; Suarez, M.; Banogon, P.E.; Shapiro, J.P. (1997) Crit. Care Med. 25, 1425-1430.
63. Lenzo, N.P.; Garas, B.A.; French, M.A. (1997) AIDS 11, 1294-1296.
64. Carr, A.; Miller, J.; Law, M.; Cooper, D.A. (2000) AIDS 14 (3), F25-F32.
65. Masur, H. (2001) International AIDS Society USA: Topics in HIV Medicine 9, 8-11.
66. Gerard, Y.; Maulin, L.; Yazdanpanah, Y.; De La Tribonniere, X.; Amiel, C.; Maurage, C.A.; Robin, S.; Salbonniere, B.; Dhennain, C.; Mouton, Y. (2000) AIDS 14, 2723-2730.
67. John, M.; Moore, C.B.; James, I.R.; Nolan, D.; Upton, R.P.; McKinnon, E.J.; Mallal, S.A. (2001) AIDS 15, 717-723.
68. Brinkman, K.; Vrouenraets, S.M.E.; Kauffman, R.; Weigel, H.; Frissen, J. (2000) AIDS 14, 2801-2802.
69. Lonergan, J.T.; Havlir, D.; Barber, E.; Mathews, W.C. (2001) Program and abstracts of the 8th Conference on Retroviruses and opportunistic Infections; Chicago, Illinois [abstract 9].
70. Boxwell, D.E. and Styrt, B.A. (1999) 39th International Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California [abstract 1284].
71. Fortgang, I.; Belitsos, P.; Chaisson, R.; Moore, R. (1995) Am. J. Gastroenterology 90, 1433-36.
72. Steinberg, M.E. (1997) J. Musculoskeletal. Med. 14, 13-25.
73. Monier, P.; McKown, K.; Bronze, M.S. (2000) ACID 31, 1488-1492.
74. Timpone, J.; Fluhme, D.; Nascone, J.; Evans, B.; Kumar, P. (1999) Sixth Conference on Retroviral and Opportunistic Infections, Chicago, Illinois [abstract 680].
75. Roudier, L. and Viard, J. (2000) AIDS [Letter] 14, 2056.
76. Meyer, D.; Behrens, G.; Schmidt, R.E.; Stoll, M. (1999) AIDS [Letter] 13, 1147-1148.
77. Scribner, A.N.; Troia-Cancio, P.V.; Cox, B.A.; Marcantonio, D.; Hamid, F.; Keiser, P.; Levi, M.; Allen, B.; Murphy, K.; Jones, R.E.; Skiest, O.J. (2000) J. Acquir. Immune. Defic. Syndr. 25, 19-25.
78. Glesby, M. and Vaamonde, C. (2000) Antiretroviral. Therapy 5 (suppl. 5), 21.
79. Paton, N.I.J.; Macallan, D.C.; Griffin, G.E.; Pazianas, M. (1997) Calcified Tissue International 61, 30-32.
80. Tebas, P.; Powderly, W.G.; Claxton, S.; Marin, D.; Tantisiriwat, W.; Teitelbaum, S.L.; Yarasheski, K.E. (2000) AIDS 14, F63-F67.
81. Hoy, J.; Hudson, J.; Law, M.; Cooper, D.A. (2000) 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, California [abstract 208].
82. Tebas, P.; Yarasheski, K.E.; Whyte, M.; Claxton, S.; DeMarco, D.; Powderly, W.G. (2000) Second International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Toronto, Ontario [abstract 029].
83. Mora, S.; Sala, N.; Bricalli, D.; Zuin, G.; Chiumello, G.; Vigano, A. (2001) AIDS 15, 1823-1829.
84. Chen, C.; Vazquez-Padua, M.; Cheng, Y. (1991) Molecular Pharmacology 39, 625-28.
85. Brinkman, K.; ter Hofstede, H.J.M.; Burger, D.M.; Smeitink, J.A.; Koopmans, P.P. (1998) AIDS 12, 1735-44.
86. Lonergan, J.T.; Havlin, D.; Behling, C.; Pfander, H.; Hassanein, T.; Mathews, W.C. (2000) ACID 31, 162-166.
87. Brinkman, K. (2000) ACID 31, 167-69.
88. Ginspoon, S.K.; Baum, H.B.A.; Kim, V.; Coggins, C.; Klibanski, A. (1995) J. Endocrinol. Metab. 80, 3628-3633.
89. Carr, A.; Miller, J.; Eisman, J.A.; Cooper, D.A. (2001) AIDS 15, 703-709.
90. Huang, J.S.; Rietschel, P.; Hadigan, C.M.; Rosenthal, D.I.; Grinspoon, S. (2001) AIDS 15, 975-982.
91. Brinkman, K.; Smeitink, J.A.; Romijin, J.A.; Reiss, P. (1999) Lancet 354, 1112-15.
92. Klopstock, T.; Naumann, M.; Seibel, P.; Shalke, B.; Reiners, K.; Reichmann, H. (1997) Mol. Cell Biochem. 174, 271-75.
93. Becker-Wegrerich, P.; Steuber, M.; Olbrisch, R.; Ruzicka, T.; Auburger, G.; Hofhaus, G. (1998) Arch. Dermatol. Res. 290, 652-55.
94. Shikuma, C.M.; Hu, H..; Milne, C.; Yost, F.; Waslien, C.; Shimizu, S.; Shiramizu, B. (2001) AIDS 15, 1801-1809.
95. Zaera, M.G.; Miro, O.; Pedrol, E.; Soler, A.; Picon, M.; Cardellach, F.; Casademont, J.; Nunes, V. (2001) AIDS 15, 1643-1651.
96. Moyle, G. (2001) AIDS [letter] 15, 413-415.
97. Walker, U.A.; Bickel, M.; Lutke-Volksbeck, S.I.; et al. (2000) 2nd International Workshop on Adverse Drug Interations and Lipodystrophy, Toronto, Ontario [abstract 06].
98. Chinnery, P.F.; Howell, N.; Andrews, R.M.; Turbull, D.M. (1999) J. Med. Genet. 36, 425-436.
99. Ware, L.J.; Morelese, J.; Burdge, G.; et al. (2000) 2nd International Workshop on Adverse Drug Interactions and Lipodystrophy, Toronto, Ontario [abstract 020].
100. Roge, B.T.; Calbert, J.; Moller, K.; et al. (2000) 2nd International Workshop on Adverse Drug Interactions and Lipodystrophy, Toronto, Ontario [abstract P22].
101. Bassetti, S.; Battegay, M.; Furrer, H.; Rickenbach, M.; Flepp, M.; Kaiser, L.; Telenti, A.; Vernazza, P.L.; Bernasconi, E.; Sudre, P. (1999) J. Acquir. Immune. Defic. Syndr. 21, 114-19.
102. Harrington, M. and Carpenter, C.C.J. (2000) Lancet 355, 2147-52.
103. Aversal, S. and Kimberlin, C. (1996) Patient Educ. Couns. 29, 207-19.
104. Aversal, S.; Kimberlin, C.; Segal, R. (1998) Qual. Life Res. 7, 205-14.
105. Morris, L.S. and Schulz, R.M. (1993) Clin. Ther. 15, 593-606.
106. Burgos, M.; Revsin, N.S.; Vilas, A.; Fontan, L. (1998) International Conference on AIDS, Geneva, Switzerland [abstract 32400].
107. Vanhove, G.F.; Schapiro, J.M.; Winters, M.A.; Merigan, T.C.; Blaschke, T.F. (1999) JAMA 276, 1955-56.
108. Bangsberg, D.R.; Hecht, F.M.; Charlebois, E.D.; Zolopa, A.R.; Holodniy, M.; Sheiner, L.; Bamberger, J.D.; Chesney, M.A.; Moss, A. (2000) AIDS 14, 357-66.