CBFβ allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium

Nature Structural and Molecular Biology

Volumn 11, Issue 9, 2004, Pages 901-906

  Yan, Jiangli ^a,c   Liu, Yizhou ^a   Lukasik, Stephen M ^a   Speck, Nancy A ^b   Bushweller, John H ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORE BINDING FACTOR; CORE BINDING FACTOR BETA; DNA; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; NITROGEN; ONCOPROTEIN; TRANSCRIPTION FACTOR AP 2;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DNA CONFORMATION; DNA PROTEIN COMPLEX; ENERGY TRANSFER; EQUILIBRIUM CONSTANT; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; BINDING SITE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TIME;

ALLOSTERIC SITE; BINDING SITES; CALORIMETRY; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DIMERIZATION; DNA; DNA-BINDING PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NITROGEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; TIME FACTORS; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS;

EID: 4344649812     PISSN: 15459993     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsmb819     Document Type: Article

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