-
2
-
-
0024160877
-
Role of insulin resistance in human disease
-
Reaven G.M. Role of insulin resistance in human disease. Diabetes. 37:1988;1595-1607
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
3
-
-
0024391834
-
The deadly quartet: Upperbody obesity, glucose intolerance, hypertriglycemia, and hypertension
-
Kaplan N.M. The deadly quartet Upperbody obesity, glucose intolerance, hypertriglycemia, and hypertension. Arch Intern Med. 149:1989;1514-1520
-
(1989)
Arch Intern Med
, vol.149
, pp. 1514-1520
-
-
Kaplan, N.M.1
-
4
-
-
0026021161
-
A hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo R.A., Ferrannini E. A hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 14:1991;173-194
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
Defronzo, R.A.1
Ferrannini, E.2
-
5
-
-
0023117178
-
Contribution of intraabdominal visceral fat accumulation to the impairment of glucose and lipid metabolism in human obesity
-
Fujioka S., Matsuzawa Y., Tokunaga K., et al. Contribution of intraabdominal visceral fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism. 36:1987;54-59
-
(1987)
Metabolism
, vol.36
, pp. 54-59
-
-
Fujioka, S.1
Matsuzawa, Y.2
Tokunaga, K.3
-
6
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 346:2002;393-403
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
-
7
-
-
0030935652
-
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and diabetes study
-
Pan X.R., Li G.W., Hu Y.H., et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and diabetes study. Diabetes Care. 20:1977;537-544
-
(1977)
Diabetes Care
, vol.20
, pp. 537-544
-
-
Pan, X.R.1
Li, G.W.2
Hu, Y.H.3
-
8
-
-
0018098853
-
Kinetics of human connecting peptide in normal and diabetic subjects
-
Faber O.K., Hagen C., Binder C., et al. Kinetics of human connecting peptide in normal and diabetic subjects. J Clin Invest. 62:1978;197-203
-
(1978)
J Clin Invest
, vol.62
, pp. 197-203
-
-
Faber, O.K.1
Hagen, C.2
Binder, C.3
-
9
-
-
0018956367
-
Prehepatic insulin production in men: Kinetic analysis using peripheral connecting peptide behavior
-
Eaton R.P., Allen R.C., Schade D.S., et al. Prehepatic insulin production in men Kinetic analysis using peripheral connecting peptide behavior. J Clin Endocrinol Metab. 51:1980;520-528
-
(1980)
J Clin Endocrinol Metab
, vol.51
, pp. 520-528
-
-
Eaton, R.P.1
Allen, R.C.2
Schade, D.S.3
-
10
-
-
0022572232
-
Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients
-
Polonsky K.S., Licinio-Paixao J., Given B.D., et al. Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients. J Clin Invest. 77:1986;98-105
-
(1986)
J Clin Invest
, vol.77
, pp. 98-105
-
-
Polonsky, K.S.1
Licinio-Paixao, J.2
Given, B.D.3
-
11
-
-
0031846461
-
How to measure insulin sensitivity
-
Ferrannini E., Mari A. How to measure insulin sensitivity. J Hypertens. 16:1998;895-906
-
(1998)
J Hypertens
, vol.16
, pp. 895-906
-
-
Ferrannini, E.1
Mari, A.2
-
12
-
-
0018487598
-
Quantitative estimation of insulin sensitivity
-
Bergman R.N., Ider Y.Z., Bowden C.R., et al. Quantitative estimation of insulin sensitivity. Am J Physiol. 236:1979;E667-E677
-
(1979)
Am J Physiol
, vol.236
-
-
Bergman, R.N.1
Ider, Y.Z.2
Bowden, C.R.3
-
13
-
-
0025300177
-
A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes
-
Finegood D.T., Hramiak I.M., Dupre J. A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes. J Clin Endocrinol Metab. 70:1990;1538-1549
-
(1990)
J Clin Endocrinol Metab
, vol.70
, pp. 1538-1549
-
-
Finegood, D.T.1
Hramiak, I.M.2
Dupre, J.3
-
14
-
-
0030775141
-
Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol
-
Saad M.F., Steil G.M., Riad-Gabriel M., et al. Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol. Diabetes. 46:1997;2044-2048
-
(1997)
Diabetes
, vol.46
, pp. 2044-2048
-
-
Saad, M.F.1
Steil, G.M.2
Riad-Gabriel, M.3
-
15
-
-
0023809501
-
First phase insulin response to glucose in nonobese or obese subjects with glucose intolerance: Analysis by C-peptide secretion rate
-
Kanatsuka A., Makino H., Sakurada M., et al. First phase insulin response to glucose in nonobese or obese subjects with glucose intolerance Analysis by C-peptide secretion rate. Metabolism. 37:1988;878-884
-
(1988)
Metabolism
, vol.37
, pp. 878-884
-
-
Kanatsuka, A.1
Makino, H.2
Sakurada, M.3
-
16
-
-
0034916605
-
Pathophysiologic phenotypes of Japanese subjects with varying degrees of glucose tolerance: Using the combination of C-peptide secretion rate and minimal model analysis
-
Tokuyama Y., Sakurai K., Yagui K., et al. Pathophysiologic phenotypes of Japanese subjects with varying degrees of glucose tolerance Using the combination of C-peptide secretion rate and minimal model analysis. Metabolism. 50:2001;812-818
-
(2001)
Metabolism
, vol.50
, pp. 812-818
-
-
Tokuyama, Y.1
Sakurai, K.2
Yagui, K.3
-
17
-
-
0031041609
-
Visceral adipose tissue impaires insulin secretion and insulin sensitivity but not energy expenditure in obesity
-
Macor C., Ruggeri A., Mazzonetto P., et al. Visceral adipose tissue impaires insulin secretion and insulin sensitivity but not energy expenditure in obesity. Metabolism. 46:1997;123-129
-
(1997)
Metabolism
, vol.46
, pp. 123-129
-
-
MacOr, C.1
Ruggeri, A.2
Mazzonetto, P.3
-
18
-
-
0022797049
-
MINMOD: A computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test
-
Pacini G., Bergman. MINMOD A computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed. 23:1986;113-122
-
(1986)
Comput Methods Programs Biomed
, vol.23
, pp. 113-122
-
-
Pacini, G.1
Bergman2
-
19
-
-
0026752239
-
Nutritional factors and the etiology of non-insulin-dependent diabetes mellitus: An epidemiological overview
-
Feskens E.J.M. Nutritional factors and the etiology of non-insulin-dependent diabetes mellitus An epidemiological overview. World Rev Nutr Diet. 69:1992;1-39
-
(1992)
World Rev Nutr Diet
, vol.69
, pp. 1-39
-
-
Feskens, E.J.M.1
-
20
-
-
0020072671
-
Type 2 (non-insulin-dependent) diabetes - An epidemiological overview
-
Zimmer P. Type 2 (non-insulin-dependent) diabetes - An epidemiological overview. Diabetologia. 22:1982;399-411
-
(1982)
Diabetologia
, vol.22
, pp. 399-411
-
-
Zimmer, P.1
-
21
-
-
0028085031
-
Dietary fat predicts conversion from impaired glucose tolerance to NIDDM
-
Marshall J.A., Hoag S., Shetterly S., et al. Dietary fat predicts conversion from impaired glucose tolerance to NIDDM. Diabetes Care. 17:1994;50-56
-
(1994)
Diabetes Care
, vol.17
, pp. 50-56
-
-
Marshall, J.A.1
Hoag, S.2
Shetterly, S.3
-
22
-
-
0037097039
-
Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomized trial
-
Chiasson J.L., Josse R.G., Gomis R., et al. Acarbose for prevention of type 2 diabetes mellitus The STOP-NIDDM randomized trial. Lancet. 359:2002;2072-2077
-
(2002)
Lancet
, vol.359
, pp. 2072-2077
-
-
Chiasson, J.L.1
Josse, R.G.2
Gomis, R.3
-
23
-
-
0030883933
-
Metabolic and cardiovascular assssment in moderate obesity: Effect of weight loss
-
Muscelli E., Camatra S., Catalano C., et al. Metabolic and cardiovascular assssment in moderate obesity Effect of weight loss. J Clin Endocrinol Metab. 82:1997;2937-2943
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 2937-2943
-
-
Muscelli, E.1
Camatra, S.2
Catalano, C.3
-
24
-
-
0342758616
-
Differentated long-term effects of intentional weight loss on diabetes and hypertension
-
Sjostrom C.D., Peltonen M., Wedel H., et al. Differentated long-term effects of intentional weight loss on diabetes and hypertension. Hypertension. 36:2000;20-25
-
(2000)
Hypertension
, vol.36
, pp. 20-25
-
-
Sjostrom, C.D.1
Peltonen, M.2
Wedel, H.3
-
25
-
-
0034682621
-
Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men
-
Ross R., Dagnone D., Jones P.J.H., et al. Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. Ann Intern Med. 133:2000;92-103
-
(2000)
Ann Intern Med
, vol.133
, pp. 92-103
-
-
Ross, R.1
Dagnone, D.2
Jones, P.J.H.3
-
27
-
-
0032834250
-
Evolution of β-cell dysfunction in impaired glucose tolerance and diabetes
-
Polonsky K.S. Evolution of β-cell dysfunction in impaired glucose tolerance and diabetes. Exp Clin Endocrinol Diabetes. 107:1998;S124-S127
-
(1998)
Exp Clin Endocrinol Diabetes
, vol.107
-
-
Polonsky, K.S.1
-
28
-
-
0028350685
-
Alfa- and beta-cell function in obese Zucker (fa/fa) rats: A study with the isolated perfused pancreas
-
Hirose H., Maruyama H., Kido K., et al. Alfa- and beta-cell function in obese Zucker (fa/fa) rats A study with the isolated perfused pancreas. Clin Sci. 86:1994;311-316
-
(1994)
Clin Sci
, vol.86
, pp. 311-316
-
-
Hirose, H.1
Maruyama, H.2
Kido, K.3
-
29
-
-
0028985060
-
Pancreatic β-cells in obesity: Evidence for induction of functional, morphogic and metabolic abnormalities by increased lon-chain fatty acids
-
Milburn J.L. Jr, Hirose H., Lee Y.H., et al. Pancreatic β-cells in obesity Evidence for induction of functional, morphogic and metabolic abnormalities by increased lon-chain fatty acids. J Biol Chem. 270:1995;1295-1299
-
(1995)
J Biol Chem
, vol.270
, pp. 1295-1299
-
-
Milburn Jr., J.L.1
Hirose, H.2
Lee, Y.H.3
-
30
-
-
0014594153
-
Stimulation of insulin secretion by infusion of free fatty acids
-
Crespin S.R., Greenough W.B. III, Steinberg D. Stimulation of insulin secretion by infusion of free fatty acids. J Clin Invest. 48:1969;1934-1943
-
(1969)
J Clin Invest
, vol.48
, pp. 1934-1943
-
-
Crespin, S.R.1
Greenough III, W.B.2
Steinberg, D.3
-
31
-
-
0024995157
-
A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely couplrd to fatty acid oxidation
-
Sako Y., Grill V.E. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely couplrd to fatty acid oxidation. Endocrinology. 127:1990;1580-1589
-
(1990)
Endocrinology
, vol.127
, pp. 1580-1589
-
-
Sako, Y.1
Grill, V.E.2
-
32
-
-
0027303165
-
Chronic perfusion of rat islets with palmitate suppress glucose-stimulated insulin release
-
Elks M.L. Chronic perfusion of rat islets with palmitate suppress glucose-stimulated insulin release. Endocrinology. 133:1993;208-214
-
(1993)
Endocrinology
, vol.133
, pp. 208-214
-
-
Elks, M.L.1
-
33
-
-
0033794857
-
In vivo and in vitro suppression by leptin of glucose-stimulated insulin hypersecretion in high glucose-ded rats
-
Widdup G., Bryson J.M., Pawlak D., et al. In vivo and in vitro suppression by leptin of glucose-stimulated insulin hypersecretion in high glucose-ded rats. Eur J Endocrinol. 143:2000;431-437
-
(2000)
Eur J Endocrinol
, vol.143
, pp. 431-437
-
-
Widdup, G.1
Bryson, J.M.2
Pawlak, D.3
-
34
-
-
0034969285
-
TNF alfa and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T 15 pancreatic cells
-
Tsiotra P.C., Tsigos C., Raptis S.A. TNF alfa and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T 15 pancreatic cells. Int J Obes Relat Metab Disord. 25:2001;1018-1026
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, pp. 1018-1026
-
-
Tsiotra, P.C.1
Tsigos, C.2
Raptis, S.A.3
-
35
-
-
0032698952
-
Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells)
-
Ahren B., Havel P.J. Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells). Am J Physiol. 277:1999;R959-R966
-
(1999)
Am J Physiol
, vol.277
-
-
Ahren, B.1
Havel, P.J.2
-
36
-
-
0033044994
-
Leptin suppression of insulin secretion and gene expression in human pancreatic islets: Implications for the development of adipogenic diabetes mellitus
-
Seufert J., Kieffer T.J., Leech C.A., et al. Leptin suppression of insulin secretion and gene expression in human pancreatic islets Implications for the development of adipogenic diabetes mellitus. J Clin Endocrinol Metab. 84:1999;670-676
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 670-676
-
-
Seufert, J.1
Kieffer, T.J.2
Leech, C.A.3
-
37
-
-
0032169556
-
Leptin inhibits insulin secretion by activation of phosphodiesterase 3B
-
Zhao A.Z., Bornfeldt K.E., Beavo J.A. Leptin inhibits insulin secretion by activation of phosphodiesterase 3B. J Clin Invest. 102:1998;869-873
-
(1998)
J Clin Invest
, vol.102
, pp. 869-873
-
-
Zhao, A.Z.1
Bornfeldt, K.E.2
Beavo, J.A.3
-
38
-
-
0034950377
-
Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion
-
Khan A., Narangoda S., Ahren B., et al. Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion. Int J Obes Relat Metab Disord. 25:2001;816-821
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, pp. 816-821
-
-
Khan, A.1
Narangoda, S.2
Ahren, B.3
-
39
-
-
0033781729
-
Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells
-
Islam M.S., Sjoholm A., Emilsson V. Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells. Int J Obes Relat Metab Disord. 24:2000;1246-1253
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 1246-1253
-
-
Islam, M.S.1
Sjoholm, A.2
Emilsson, V.3
-
40
-
-
0034969285
-
TNF alfa and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T15 pancreatic cells
-
Tsiotra P.C., Tsigos C., Raptis S.A. TNF alfa and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T15 pancreatic cells. Int J Obes Relat Metab Disord. 25:2001;1018-1026
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, pp. 1018-1026
-
-
Tsiotra, P.C.1
Tsigos, C.2
Raptis, S.A.3
-
41
-
-
0035125097
-
Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo
-
Cases J.A., Gabriely I., Ma X.H., et al. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes. 50:2001;348-352
-
(2001)
Diabetes
, vol.50
, pp. 348-352
-
-
Cases, J.A.1
Gabriely, I.2
Ma, X.H.3
-
42
-
-
0033794857
-
In vivo and in vitro suppression by leptin of glucose-stimulated insulin hypersecretion in high glucose-fed rats
-
Widdup G., Bryson J.M., Pawlak D., et al. In vivo and in vitro suppression by leptin of glucose-stimulated insulin hypersecretion in high glucose-fed rats. Eur J Endocrinol. 143:2000;431-437
-
(2000)
Eur J Endocrinol
, vol.143
, pp. 431-437
-
-
Widdup, G.1
Bryson, J.M.2
Pawlak, D.3
-
43
-
-
0027947379
-
β-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-β cell relationships
-
Lee Y., Hirose H., Ohneda M., et al. β-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats Impairment in adipocyte-β cell relationships. Proc Natl Acad Sci USA. 91:1994;10878-10882
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10878-10882
-
-
Lee, Y.1
Hirose, H.2
Ohneda, M.3
-
44
-
-
0033613181
-
Troglitazone prevents mitochondrial alterations, β cell destruction, and diabetes in obese prediabetic rats
-
Higa M., Zhou Y.-T., Ravazzola M., et al. Troglitazone prevents mitochondrial alterations, β cell destruction, and diabetes in obese prediabetic rats. Proc Natl Acad Sci USA. 96:1999;11513-11518
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11513-11518
-
-
Higa, M.1
Zhou, Y.-T.2
Ravazzola, M.3
-
45
-
-
15844381594
-
Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
-
Shimomura I., Funahashi T., Takahashi M., et al. Enhanced expression of PAI-1 in visceral fat Possible contributor to vascular disease in obesity. Nat Med. 2:1996;800-803
-
(1996)
Nat Med
, vol.2
, pp. 800-803
-
-
Shimomura, I.1
Funahashi, T.2
Takahashi, M.3
-
46
-
-
0029827134
-
Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice
-
Samad F., Loskutoff D.J. Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice. Mol Med. 2:1996;568-582
-
(1996)
Mol Med
, vol.2
, pp. 568-582
-
-
Samad, F.1
Loskutoff, D.J.2
-
47
-
-
0030975615
-
Production of plasminogen activator inhibitor 1 by human adipose tissue: Possible link between visceral fat accumulation and vascular disease
-
Alessi M.C., Peiretti F., Morange P., et al. Production of plasminogen activator inhibitor 1 by human adipose tissue Possible link between visceral fat accumulation and vascular disease. Diabetes. 46:1997;860-867
-
(1997)
Diabetes
, vol.46
, pp. 860-867
-
-
Alessi, M.C.1
Peiretti, F.2
Morange, P.3
-
48
-
-
0033047930
-
Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women
-
Mavri A., Stegnar M., Krebs M., et al. Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women. Arterioscler Thromb Vasc Biol. 19:1999;1582-1587
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1582-1587
-
-
Mavri, A.1
Stegnar, M.2
Krebs, M.3
|