Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 6, 1999, Pages 1582-1587

  Mavri, Alenka ^a,b   Stegnar, Mojca ^a   Krebs, Michael ^b   Sentočnik, Jožica T ^c   Geiger, Margarethe ^b   Binder, Bernard R ^b  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^b UNIVERSITY OF VIENNA   (Austria)

^c Medical Aestetic Centre   (Slovenia)

Author keywords

Adipose tissue; Adipsin; Diet; Leptin; Plasminogen activator inhibitor 1

Indexed keywords

ADIPSIN; INSULIN; LEPTIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADULT; ARTICLE; BODY FAT; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; FEMALE; HUMAN; LOW CALORY DIET; MAJOR CLINICAL STUDY; OBESITY; PRIORITY JOURNAL; WEIGHT REDUCTION;

EID: 0033047930     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.6.1582     Document Type: Article

References (39)

1. Loskutoff DJ. Regulation of PAI-1 gene expression. Fibrinolysis. 1991; 5:197-201.
2. McGill JB, Schneider DJ, Arfken CL, Lucore CL, Sobel BE. Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients. Diabetes. 1994;43:104-109.
3. Vague P, Juhan-Vague I, Chabert V, Alessi MC, Atlan C. Fat distribution and plasminogen activator inhibitor activity in nondiabetic obese women. Metabolism. 1989;38:913-915.
4. Urano T, Kojima Y, Takahashi M, Serizawa K, Sakakibara K, Takada Y, Takada A. Impaired fibrinolysis in hypertension and obesity due to high plasminogen activator inhibitor-1 level in plasma. Jpn J Physiol. 1993; 43:221-228.
5. De Pergola G, De Mitrio V, Perricci A, Cignarelli M, Garruti G, Lomuscio S, Ferri G, Schiraldi O, Giorgino R. Influence of free testosterone on antigen levels of plasminogen activator inhibitor-1 in premenopausal women with central obesity. Metabolism. 1992;41:131-134.
6. Landin K, Stigendal L, Eriksson E, Krotkiewski M, Risberg B, Tengborn L, Smith U. Abdominal obesity is associated with an impaired fibrinolytic activity and elevated plasminogen activator inhibitor-1. Metabolism. 1990;39:1044-1048.
7. Vague P, Juhan-Vague I, Aillaud MF, Badier C, Viard R, Alessi MC, Collen D. Correlation between blood fibrinolytic activity, plasminogen activator inhibitor level, plasma insulin level, and relative body weight in normal and obese subjects. Metabolism. 1986;35:250-253.
8. Juhan-Vague I, Vague P, Alessi MC, Badier C, Valadier J, Aillaud MF, Atlan C. Relationships between plasma insulin, triglyceride, body mass index, and plasminogen activator inhibitor 1. Diabetes Metab. 1987;13:
9. Juhan-Vague I, Thompson SG, Jespersen J, on behalf of the ECAT Angina Pectoris Study Group. Involvement of the hemostatic system in the insulin resistance syndrome: a study of 1500 patients with angina pectoris. Arterioscler Thromb. 1993;13:1865-1873.
10. Hamsten A, Walldius G, Szamozi A, Blombäck M, de Faire U, Dahlen G, Landou C, Wiman B. Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet. 1987;2:3-9.
11. Juhan-Vague I, Pyke SDM, Alessi MC, Jespersen J, Haverkate F, Thompson SG. Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. Circulation. 1996;94: 2057-2063.
12. Manson JE, Willett WC, Stampfer MJ, Colditz GA, Hunter DJ, Hankinson SE, Hennekens CH, Speizer FE. Body weight and mortality among women. N Engl J Med. 1995;333:677-685.
13. Folsom AR, Qamhieh HT, Wing RR, Jeffery RW, Stinson VL, Kuller LH, Wu KK. Impact of weight loss on plasminogen activator inhibitor (PAI-1), factor VII, and other hemostatic factors in moderately overweight adults. Arteriosder Thromb. 1993;13:162-169.
14. Palaretti G, Legnani C, Poggi M, Parenti M, Babini AC, Biagi R, Baraldi L, Luchi A, Capelli M, Coccheri S. Prolonged very low calorie diet in obese subjects reduces factor VII and PAI but not fibrinogen levels. Fibrinolysis. 1994;8:16-21.
15. Huisveld IA, Leenen R, vd Kooy K, Hospers JEH, Seidel JC, Deurenberg P, Koppeschaar HPF, Mosterd WL, Bouma BN. Body composition and weight reduction in relation to antigen and activity of plasminogen activator inhibitor (PAI-1) in overweight individuals. Fibrinolysis 1990; 4(suppl 2):84-85.
16. Mehrabian M, Peter JB, Bernard RJ, Lusis AJ, Dietary regulation of fibrinolytic factors. Atherosclerosis. 1990;84:25-32.
17. Svendsen OL, Hassager C, Christiansen C, Nielsen JD, Winther K. Plasminogen activator inhibitor-1, tissue-type plasminogen activator, and fibrinogen: effect of dieting with or without exercise in overweight postmenopausal women. Arteriosder Thromb Vasc Biol. 1996;16: 381-385.
18. Sundell IB, Dahlgren S, Rånby M, Lundin E, Stenling R, Nilsson TK. Reduction of elevated plasminogen activator inhibitor levels during modest weight loss. Fibrinolysis. 1989;3:51-53.
19. Peternel P, Stegnar M, Mavri A, Salobir-Pajniè B. The effect of fasting and/or body weight reduction on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI-1). Fibrinolysis. 1994;8(suppl 2):41-43.
20. Sawdey M, Loskutoff DJ. Regulation of murine type-1 plasminogen activator inhibitor gene expression in vivo: tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β. J Clin Invest. 1991;88:1346-1353.
21. Samad F, Yamamoto K, Loskutoff DJ. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. J Clin Invest. 1996;97:37-46.
22. Loskutof DJ, Samad F. The adipocyte and hemostatic balance in obesity: studies of PAI-1. Arterioscler Thromb Vasc Biol. 1998;18:1-6.
23. White RT, Damm D, Hancock N, Rosen BS, Lowell BB, Usher P, Flier JS, Spiegelman BM. Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem. 1992-267: 9210-9213.
24. Cianflone K, Maslowska M, Sniderman A. The acylation stimulating protcin-adipsin system. Int J Obes. 1995;19(suppl 1):S34-S38.
25. Flier JS, Cook KS, Usher P, Spiegelman BM. Severely impaired adipsin in genetic and acquired obesity. Science. 1987;237:405-408.
26. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med. 1995;1:1155-1161.
27. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science. 1993;259:87-91.
28. Bray GA. Pathophysiology of obesity. Am J Clin Nutr 1992;55: 488S-494S.
29. Lean MEJ, Han TS, Deurenberg P. Predicting body composition by densitometry from simple anthropometric measurements. Am J Clin Nutr. 1996;36:4-14.
30. Bondar RJL, Mead DC. Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum. Clin Chem. 1974;20:586-590.
31. Fossati P. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982;28: 2077-2080.
32. Oppermann M, Baumgarten H, Brandt E, Gottsleben, Kurts C, Götze O. Quantitation of components of the alternative pathway of the complement (APC) by enzyme-linked immunosorbent assay. J Immunol Methods. 1990;133:181-190.
33. Alessi MC, Juhan-Vague I, Kooistra T, Declerk PJ, Collen D. Insulin stimulates the synthesis of plasminogen activator inhibitor 1 by the human hepatocellular cell line Hep G2. Thromb Haemost. 1988;60: 491-494.
34. Stiko-Rahm A, Wiman B, Hamsten A, Nilsson J. Secretion of plasminogen activator inhibitor 1 from cultured human umbilical vein endothelial cells is induced by very low density lipoprotein. Arteriosclerosis. 1990; 10:1067-1073.
35. Juhan-Vague I, Alessi MC, Vague P. Increased plasma plasminogen activator inhibitor 1 levels: a possible link between insulin resistance and atherothrombosis. Diabetologia. 1991;34:457-462.
36. Alessi MC, Pieretti F, Morange M, Henry M, Nalbone G, Juhan-Vague I. Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease. Diabetes. 1997;46:860-867.
37. Alessi MC, Parrot G, Guenoun E, Scelles V, Vague P, Juhan-Vague I. Relation between plasma PAI activity and adipsin levels. Thromb Haemost. 1995;74:1200-1202.
38. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996;334:292-295.
39. Napolitano A, Lowell BB, Damm D, Leibel RL, Ravussin E, Jimerson DJ, Lesem MD, Van Dyke DC, Daly PA, Chatis P, Tyler White R, Spiegelman BM, Flier JS. Concentrations of adipsin in blood and rates of adipsin secretion by adipose tissue in humans with normal, elevated and diminished adipose tissue mass. Int J Obes Relat Metab Disord. 1994;18:213-218.