JNK MAP kinase is involved in the humoral immune response of the greater wax moth larvae Galleria mellonella

Archives of Insect Biochemistry and Physiology

Volumn 56, Issue 4, 2004, Pages 143-154

  Wojda, Iwona ^a   Kowalski, Patryk ^a   Jakubowicz, Teresa ^a  

^a MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

Author keywords

Galleria mellonello; Insect immunity; JNK MAP kinase; Protein phosphorylation

Indexed keywords

ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; ENZYME INHIBITOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL; ARTICLE; ENZYME ACTIVATION; ENZYMOLOGY; FAT BODY; HEMOLYMPH; IMMUNOLOGY; METABOLISM; MOTH; PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTHRACENES; BLOTTING, WESTERN; ENZYME ACTIVATION; ENZYME INHIBITORS; FAT BODY; HEMOLYMPH; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MOTHS; PHOSPHORYLATION;

GALLERIA; GALLERIA MELLONELLA; INSECTA; LEPIDOPTERA;

EID: 4344607800     PISSN: 07394462     EISSN: None     Source Type: Journal    
DOI: 10.1002/arch.20001     Document Type: Article

References (35)

1. Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B, Perrimon N. 2003. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev Cell 5:441-445.
2. Anderson KV, Nusslein-Volhard C. 1984. Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 311:223-227.
3. Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce AS, Satoh Y, Bhagwat SS, Manning AM, Anderson DW. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. PNAS 98:13681-13686.
4. Boman HG, Nilsson-Faye I, Paul K, Rasmuson T Jr. 1974. Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cythia pupae. Infect Immun 10:136-145.
5. Boutros M, Agaisse H, Perrimon N. 2002. Sequential activation of signalling pathways during innate immune responses in Drosophila. Cell 3:711-722.
6. Bradford M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 72:248.
7. Bulet P, Hetru Ch, Dimarcq J-L, Hoffmann D. 1999. Antimicrobial peptides in insects; structure and function. Dev Comp Immunol 23:329-344.
8. Canesi L, Betti M, Ciacci C, Scarpato A, Citterio B, Carla Pruzzo Gallo G. 2002a. Signalling pathways involved in the physiological response of mussel hemocytes to bacterial challenge: the role of stress-activated p38 MAP kinases. Dev Comp Immunol 26:325-334.
9. Canesi L, Scarpato A, Betti M, Ciacci C, Pruzzo C, Gallo G. 2002b. Bacterial killing by Mytilus hemocyte monolayers as a model for investigating the signaling pathways involved in mussel immune defence. Mar Env Res 54:547-551.
10. Chalk R, Townson H, Natori S, Desmond H, Ham PJ. 1994. Purification of an insect defensin from the Mosquito, Aedes aegypti. Insect Biochem Mol Biol 24:403-410.
11. Cytryńska M, Zdybicka-Barabas A, Jabloński P, Jakubowicz T. 2001. Detection of antibacterial polvpeptide activity in situ after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 299:274-276.
12. De Gregorio E, Spellman PT, Rubin GM, Lemaitre B. 2001. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. PNAS 98:12590-12595.
13. De Gregorio E, Spellman PT, Tzou P, Rubin GM, Lemaitre B. 2002. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. The EMBO J 21:2568-2579.
14. Dong Ch, Davis R, Flavell RA. 2002. MAP kinases in the immune response. Annu Rev Immunol 20:55-72.
15. Ekengren S, Tryselius Y, Dushay MS, Liu G, Steiner H, Hultmark D. 2001. A humoral stress in Drosophila. Curr Biol 11:714-718.
16. Engström Y. 1999. Induction and regulation of antimicrobial peptides in Drosophila. Dev Comp Immunol 23:263-442.
17. Han Z, Enslen H, Hu X, Meng X, Wu I-H, Barrett T, Davis RJ, Ip YT. 1998. A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol Cell Biol 18:3527-3539.
18. Hetru Ch, Troxler L, Hoffman JA. 2003. Drosophila melanogaster antimicrobial defense. JID 187:327334.
19. Hultmark D. 1998. Quantification of antimicrobial activity using the inhibition-zone assay. In: Wiesner A, Dunphy GB, Marmaras VJ, Morishima I, Sugumaran M, Yamakawa M, editors. Techniques in insect immunology. Fair Heaven: SOS Publications.
20. Hultmark D. 2003. Drosophila immunity; paths and patterns. Curr Op Immunol 15:12-19.
21. Irving P, Troxler L, Heuer TS, Belvin M, Kopczynski C, Reichhart J-M, Hoffmann JA, Hetru Ch. 2001. A genome-wide analysis of immune responses in Drosophila. PNAS 98:15119-15124.
22. Khush RS, Lemaitre B. 2000. Genes that fight infection, what the Drosophila genome says about animal immunity. TIG 16:442-448.
23. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
24. Lemaitre B, Reichhart JM, Hoffmann JA. 1997. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. PNAS 94:14614-14619.
25. McLeish KR, Klein JB, Coxon PY, Head KZ, Ward RA. 1998. Bacterial phagocytosis activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in neutrophils. J Leuk Biol 64:835-844.
26. Mizutani T, Kobayashi M, Eshita Y, Shirato K, Kimura T, Ako Y, Miyoshi T, Takasaki T, Kurane I, Kariwa H, Umemura T, Takashima T. 2003. Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytoses, endocytosis and infection of the West Nile virus. Insect Mol Biol 12:491.
27. Perskvist N, Zheng L, Stendahl O. 2000. Activation of human neutrophils in Mycobacterium tuberculosis H37Ra involves phospholipase Cγ2, She adapter protein, and p38 mitogen-activated protein kinase. J Immunol 164:959-965.
28. Procyk KJ, Kovarik P, von Gabain A, Baccarini M. 1999. Salmonella thypimurium and lipopolisaccharide stimulate extracellularly regulated kinase activation in macrophages by a mechanism involving phosphatidilinositol 3-kinase and phospholipase D as novel intermediates. Infect Immun 67:1011-1017.
29. Schaefer HJ, Weber MJ. 1999. Mitogen-activated protein kinases: specific messages from ubiquititous messengers. Mol Cell Biol 19:2435-2444.
30. Schmolz E, Schulz O. 1995. Colorimetric investigations on thermoregulation and growth of wax moth larvae Galleria mellonella. Thermochimica A 251:241-245.
31. Sehnal, F. 1966. Kritishes Studium der Bionomie und Biometrik der in verschiedenen Lebensbedingungen gezüchteten Wachsmotte Galleria mellonella. Z Wiss Zool 174:53-82.
32. Silverman N, Maniatis T. 2001. NF-B signaling pathways in mammalian and insect innate immunity. Genes Dev 15:2321-2342.
33. Sluss HK, Han Z, Berrett T, Davis RJ, Ip YT. 1996. A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev 10:2745-2758.
34. Vidal S, Khush RS, Leulier F, Tzou P, Nakamura M, Lemaitre B. 2001. Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/ NF-κB-dependent innate immune responses. Gen Dev 15:1900-1912.
35. Yamamori T, Inanami O, Nagahata H, Cui YD, Kuwabara M. 2000. Roles of p38 MAPK, PKC and PI-Kin the signalling pathways of NADPH oxidase activation and phagocytosis in bovine polymorphonuclear leukocytes. FEBS Lett 467:253-258.