Susceptibility to collagen-induced arthritis: Cytokine-mediated regulation

Clinical Immunology

Volumn 98, Issue 1, 2001, Pages 109-118

  Ortmann, Robert A ^a   Shevach, Ethan M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Collagen induced arthritis; Cytokines; Knockout mice; MHC restriction; Th1 Th2 cells

Indexed keywords

COLLAGEN; CYTOKINE; FREUND ADJUVANT;

ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTHRITIS; ARTICLE; AUTOIMMUNITY; COMPLEMENT FIXATION; DRUG INDUCED DISEASE; GENE DELETION; GENE DISRUPTION; HAPLOTYPE; IMMUNIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

EID: 0035182141     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2000.4961     Document Type: Article

References (40)

1. Autoimmunity to type II collagen: An experimental model
2. Immunization against heterologous type II collagen induces arthritis in mice
3. Type II collagen autoimmunity in animals and provocations leading to arthritis
4. Type collagen-induced arthritis in mice. I. Major Histocompatibility Complex (I region) linkage and antibody correlates
5. Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
6. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors
7. Accelerated collagen-induced arthritis in IFN-γ receptor-deficient mice
8. Interferon-γ confers resistance to experimental allergic encephalomiyelitis
9. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
10. Genetic control of collagen-induced arthritis in rats: The immune response to type II collagen among susceptible and resistant strains and evidence for multiple gene control
11. Interleukin-6 is required for the development of collagen-induced arthritis
12. Type II collagen-induced arthritis. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity
13. Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-γ receptor deficient mice
14. 1 mice with monoclonal antibody to γ interferon
15. Experimental therapy of systemic lupus erythematosis: The treatment of NZB/W mice with soluble interferon-γ receptor inhibits the onset of glomerulonephritis
16. Essential role for interferon-γ and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice
17. Essential pathogenic role for endogenous interferon-γ (IFN-γ) during disease onset phase of murine experimental auotimmune orchitis. I. In vivo studies
18. Biphasic effect of interferongamma in murine collagen-induced arthritis
19. Administration of interleukin-12 in combination with type II collagen induces severe arthritis in DBA/1 mice
20. Reduced incidence of collagen-induced arthritis in interleukin-12-deficient mice
21. The effect of treatment with interferon-gamma on type II collagen-induced arthritis
22. Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis
23. IL-12 promotes cellular but not humoral type II collagen-specific Th1-type responses in C57BL/6 and B10.Q mice and fails to induce arthritis
24. b) mice: New insights into an important disease model of rheumatoid arthritis
25. IFN-γ deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response
26. IFN-γ-deficient mice develop severe granulomatous experimental autoimmune thyroiditis with eosinophil infiltration in thyroids
27. IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
28. Failure to suppress the expansion of the activated CD4 T cell population in interferon-γ deficient mice leads to exacerbation of experimental auto-immune encephalomyelitis
29. Enhanced auto-immune arthritis in IFN-γ receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells
30. IFN-γ shapes immune invasion of the central nervous system via regulation of chemokines
31. Collagen-induced arthritis in mice: Relationship of collagen-specific and total IgE synthesis to disease
32. Interleukin-10 inhibition of the progression of established collagen-induced arthritis
33. Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13
34. Protective major histocompatibility complex genes and the role of interleukin-4 in collagen-induced arthritis
35. B cell-deficient mice do not develop type II collagen induced arthritis (CIA)
36. b mice susceptible to collagen-induced arthritis
37. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice
38. Properties and functions of interleukin-10
39. Dual role of IL-12 in early and late stages of murine collagen type II arthritis
40. Role of cytokines in rheumatoid arthritis