Immunohistochemical analysis of oxidative DNA damage in arsenic-related human skin samples from arsenic-contaminated area of China

Cancer Letters

Volumn 214, Issue 1, 2004, Pages 11-18

  An, Yan ^a,b   Gao, Zenglin ^b   Wang, Zhongwen ^b   Yang, Shaohe ^c   Liang, Jianfen ^d   Feng, Yan ^d   Kato, Koichi ^a   Nakano, Masayuki ^e   Okada, Shoji ^f   Yamanaka, Kenzo ^a  

^a NIHON UNIVERSITY   (Japan)

^b CHINA INSTITUTE FOR RADIATION PROTECTION   (China)

^c Workers' Hosp of Yunnan Tin Corp   (China)

^d SHANXI MEDICAL UNIVERSITY   (China)

^e NATIONAL HOSPITAL ORGANIZATION CHIBA MEDICAL CENTER   (Japan)

^f UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

8 Oxo 2 deoxyguanosine (8 oxodG); Arsenic related human skin cancers; Free radicals; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ARSENIC; DNA;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHINA; CONTROLLED STUDY; DNA STRAND BREAKAGE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATOSIS; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; SKIN CANCER; SKIN TUMOR; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ADULT; AGED; AGED, 80 AND OVER; ARSENIC POISONING; BIOPSY; CHINA; DEOXYGUANOSINE; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; OXIDATIVE STRESS; SKIN NEOPLASMS;

EID: 4344570861     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.04.005     Document Type: Article

References (35)

1. International Agency Research on Cancer. IARC monographs on the evaluation of the carcinogenic risks of the chemicals to humans. Overall Evaluations of Carcinogenicity: an Updating of IARC Monographs. 1-42 (Suppl. 7):1987;IARC, Lyon. pp. 100-106
2. Wanibuchi H., Hori T., Meenakshi V., Ichihara T., Yamamoto S., Yano Y., et al. Promotion of rat hepatocarcinogenesis by dimethylarsinic acid: association with elevated ornithine decarboxylase activity and formation of 8-hydroxydeoxyguanosine in the liver. Jpn. J. Cancer Res. 88:1997;1149-1154
3. Nordenson I., Beckman L. Is the genotoxic effect of arsenic mediated by oxygen free radicals? Hum. Hered. 41:1991;71-73
4. Hei T.K., Liu S.X., Waldren C. Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species. Proc. Natl Acad. Sci. USA. 95:1998;8103-8107
5. Rin K., Kawaguchi K., Yamanaka K., Tezuka M., Oku N., Okada S. DNA-strand breaks induced by dimethylarsinic acid, a metabolite of inorganic arsenics, are strongly enhanced by superoxide anion radicals. Biol. Pharm. Bull. 18:1995;45-48
6. Vijayaraghavan M., Wanibuchi H., Karim R., Yamamoto S., Masuda C., Nakae D., et al. Dimethylarsinic acid induces 8-hydroxy-2′-deoxyguanosine formation in the kidney of NCI-Black Reiter rats. Cancer Lett. 165:2001;11-17
7. Kitchin K.T., Ahmad S. Oxidative stress as a possible mode of action for arsenic carcinogenesis. Toxicol. Lett. 137:2003;3-13
8. Liu J., Kadiiska M., Liu Y., Qu W., Mason R.P., Waalkes M.P. Acute arsenic-induced free radical production and oxidative stress-related gene expression in mice. Toxicologist. 54:2000;280-281
9. Liu S.X., Athar M., Lippai I., Waldren C., Hei T.K. Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity. Proc. Natl Acad. Sci. 98:2001;1643-1648
10. Ahmad S., Kitchin K.T., Cullen W.R. Arsenic species that cause release of iron from ferritin and generation of activated oxygen. Arch. Biochem. Biophys. 382:2000;195-202
11. Ahmad S., Kitchin K.T., Cullen W.R. Plasmid DNA damage caused by methylated arsenicals, ascorbic acid and human liver ferritin. Toxicol. Lett. 133:2002;47-57
12. Yamanaka K., Hoshino M., Okamoto M., Sawamura R., Hasegawa A., Okada S. Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxy radical, Biochem. Biophys. Res. Commun. 168:1990;58-64
13. Yamanaka K., Hasegawa A., Sawamura R., Okada S. Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice. Biochem. Biophys. Res. Commun. 165:1989;43-50
14. Yamanaka K., Mizoi M., Kato K., Hasegawa A., Nakano M., Okada S. Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter. Biol. Pharm. Bull. 24:2001;510-514
15. Yamanaka K., Hasegawa A., Sawamura R., Okada S. Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice. Toxicol. Appl. Pharmacol. 108:1991;205-213
16. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged bases 8-oxodG. Nature. 349:1991;431-434
17. Yamanaka K., Takabayashi F., Mizoi M., An Y., Hasegawa A., Okada S. Oral exposure of dimethylarsenic acid, a main metabolite of inorganic arsenics, in mice leads to an increase in 8-oxo-2′-deoxyguanosine level, specifically in the target organs for arsenic carcinogenesis. Biochem. Biophys. Res. Commun. 287:2001;66-70
18. Matsui M., Nishigori C., Toyokuni S., Takada J., Akaboshi M., Ishikawa M., et al. The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2′-deoxyguanosine in arsenic-related Bowen's disease. J. Invest. Dermatol. 113:1999;26-31
19. Sun S.Q., Meng X.Y., Yuan L.Y., You Z.Y., Liu S.E., Yang X.O., et al. Etiological analysis of lung cancer among miners at Gejiu, Yuannan Province. Radiat. Prot. 1:1981;1-9. (Chinese)
20. Zhang F.M. The analysis of the ridge regressor about occupational factor of the lung cancer of Yunnan tin miners. Chin. J. Prevent. Med. 20:1986;151-153. (Chinese)
21. Sun S.Q., You Z.Y. Discussion on etiology of miner lung cancer in Gejiu tin mine, Yunnan Province, China. Chin. J. Radiol. Med. Protect. 7:1987;225-228
22. Liu Y.T., Chen Z., Wang A.D. Approach on etiology of Yunnan tin miner's lung cancer. Chin. J. Ind. Hyg. Occup. Dis. 5:1987;20-21. (Chinese)
23. Taylor P.R., Qiao Y.L., Schatzkin A., Yao S.X., Lubin J., Mao B.L., et al. Relation of arsenic exposure to lung cancer among tin miners in Yunnan Province, China. Br. J. Ind. Med. 46:1989;881-886
24. The Public Health Department at Gejiu City, People's Hospital of Gejiu City, The Environmental Protection Division at Gejiu City, China Institute for Radiation Protection, Investigation for health effect of arsenic in Gejiu city, Lao Dong Wei Sheng Zhi Ye Bing Zhuan Ji, 6 (1981), 32-41 (Chinese).
25. Li F.J., Sun G.F., Liang G. Clinical symptom of arsenic-intoxicated patients and arsenic pollution in China. China Public Health. 14:1998;651-652. (Chinese)
26. Weyers W., Bonczkowitz M., Weyers I., Bittinger A., Schill W.B. Melanoma in situ versus melanocytic hyperplasia in sun-damaged skin: assessment of the significance of histopathologic criteria for differential diagnosis. Am. J. Dermatopathol. 18:1996;560-566
27. Hsu S.M., Raine L., Fanger H. A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am. J. Clin. Pathol. 75:1981;734-738
28. Cattoretti G., Becker M.H., Key G., Duchrow M., Schluter C., Galle J., Gerdes J. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J. Pathol. 168:1992;357-363
29. Breimer L.H. Molecular mechanism of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage. Mol. Carcinog. 3:1990;188-197
30. Chaudhary A.K., Nokubo M., Marnett L.J., Blair I.A. Analysis of the malondialdehyde-2′-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry. Biol. Mass. Spectrom. 23:1994;457-464
31. Basset-Seguin N., Moles J.P., Mils V., Dereure O., Guilhou J.J. TP53 tumor suppressor gene and skin carcinogenesis. J. Invest. Dermatol. 103:(Suppl. 5):1994;102S-106S
32. Pierceall W.E., Mukhopadhyay T., Goldberg L.H., Ananthaswamy H.N. Mutation in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas. Mol. Carcinog. 4:1991;445-449
33. Wei M., Wanibuchi H., Morimura K., Iwai S., Yoshida K., Endo G., et al. Carcinogenesity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors. Carcinogenesis. 23:2002;1387-1397
34. Yamanaka K., Mizoi M., Tachikawa M., Hasegawa A., Hoshino M., Okada S. Oxidative DNA damage following exposure to dimethylarsinous iodide: the formation of cis-thymine glycol. Toxicol. Lett. 143:2003;145-153
35. Nesnow S., Roop B.C., Lambert G., Kadiiska M., Mason R.P., Cullen W.R., Mass M.J. DNA damaged induced by methylated trivalent arsenicals is mediated by reactive oxygen species. Chem. Res. Toxicol. 15:2002;1627-1634