The Growth-regulatory protein HCRP1/h Vps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation

Molecular Biology of the Cell

Volumn 15, Issue 9, 2004, Pages 4337-4346

  Bache, Kristi G ^a   Slagsvold, Thomas ^a   Cabezas, Alicia ^a   Rosendal, Ken R ^a   Raiborg, Camilla ^a   Stenmark, Harald ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ESCRT 1; PROTEIN HCRP1; REGULATOR PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL VACUOLE; COMPLEX FORMATION; CONFOCAL MICROSCOPY; ENDOSOME; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOSOMES; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN SUBUNITS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 4344570298     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E04-03-0250     Document Type: Article

References (44)

1. Babst, M., Katzmann, D.J., Estepa-Sabal, E.J., Meerloo, T., and Emr, S.D. (2002a). Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev. Cell 3, 271-282.
2. Babst, M., Katzmann, D.J., Snyder, W.B., Wendland, B., and Emr, S.D. (2002b). Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev. Cell 3, 283-289.
3. Babst, M., Odorizzi, G., Estepa, E.J., and Emr, S.D. (2000). Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1, 248-258.
4. Bache, K.G., Brech, A., Mehlum, A., and Stenmark, H. (2003). Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J. Cell Biol. 162, 435-442.
5. Begley, D., Murphy, A.M., Hiu, C., and Tsubota, S.I. (1995). Modifier of rudimentary p1, mod(r)p1, a trans-acting regulatory mutation of rudimentary. Mol. Gen. Genet. 248, 69-78.
6. Bilodeau, P.S., Urbanowski, J.L., Winistorfer, S.C., and Piper, R.C. (2002). The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat. Cell Biol. 4, 534-539.
7. Bishop, N., Horman, A., and Woodman, P. (2002). Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. J. Cell Biol. 157, 91-101.
8. Bishop, N., and Woodman, P. (2001). TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes. J. Biol. Chem. 276, 11735-11742.
9. Brenner, S.E., Chothia, C., and Hubbard, T.J. (1998). Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships. Proc. Natl. Acad. Sci. USA 95, 6073-6078.
10. Conibear, E. (2002). An ESCRT into the endosome. Mol. Cell 10, 215-216.
11. Drab, M., et al. (2001). Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293, 2449-2452.
12. Dupre, S., Volland, C., and Haguenauer-Tsapis, R. (2001). Membrane transport: ubiquitylation in endosomal sorting. Curr. Biol. 11, R932-R934.
13. Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
14. Garrus, J.E., et al. (2001). Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107, 55-65.
15. Guarente, L. (1983). Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101, 181-189.
16. Hicke, L. (2001). Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol. 2, 195-201.
17. Hosokawa, Y., Nagai, E., and Seto, M. (2000). Truncated TSG101 transcripts in human leukemia and lymphoma cell lines. J. Cancer Res. Clin. Oncol. 126, 79-84.
18. Huynen, M., Doerks, T., Eisenhaber, F., Orengo, C., Sunyaev, S., Yuan, Y., and Bork, P. (1998). Homology-based fold predictions for Mycoplasma genitalium proteins. J. Mol. Biol. 280, 323-326.
19. Kanazawa, C., Morita, E., Yamada, M., Ishii, N., Miura, S., Asao, H., Yoshimori, T., and Sugamura, K. (2003). Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation. Biochem. Biophys. Res. Commun. 309, 848-856.
20. Katzmann, D.J., Babst, M., and Emr, S.D. (2001). Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106, 145-155.
21. Katzmann, D.J., Odorizzi, G., and Emr, S.D. (2002). Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3, 893-905.
22. Katzmann, D.J., Stefan, C.J., Babst, M., and Emr, S.D. (2003). Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J. Cell Biol. 162, 413-423.
23. Komada, M., and Kitamura, N. (1995). Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol. Cell. Biol. 15, 6213-6221.
24. Li, L., and Cohen, S.N. (1996). Tsg 101, a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell 85, 319-329.
25. Lu, Q., Hope, L.W., Brasch, M., Reinhard, C., and Cohen, S.N. (2003). TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc. Natl. Acad. Sci. USA 100, 7626-7631.
26. Martin-Serrano, J., Zang, T., and Bieniasz, P.D. (2001): HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat. Med. 7, 1313-1319.
27. Motley, A., Bright, N.A., Seaman, M.N., and Robinson, M.S. (2003). Clathrin-mediated endocytosis in AP-2-depleted cells. J. Cell Biol. 162, 909-918.
28. Mullins, C., and Bonifacino, J.S. (2001). The molecular machinery for lysosome biogenesis. Bioessays 23, 333-343.
29. Mushegian, A.R., Bassett, D.E., Jr., Boguski, M.S., Bork, P., and Koonin, E.V. (1997). Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs. Proc. Natl. Acad. Sci. USA 94, 5831-5836.
30. O'Boyle, J.D., Proctor, M.L., Fong, K.M., Lin, W.M., Miller, D.S., and Muller, C.Y. (1999). Role of TSG101 in uterine cervix cancer. Gynecol. Oncol. 75, 401-405.
31. Odorizzi, G., Katzmann, D.J., Babst, M., Audhya, A., and Emr, S.D. (2003). Brol is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J. Cell Sci. 116, 1893-1903.
32. Ponting, C.P., Cai, Y.D., and Bork, P. (1997). The breast cancer gene product TSG 101, a regulator of ubiquitination? J. Mol. Med. 75, 467-469.
33. Pornillos, O., Garrus, J.E., and Sundquist, W.I. (2002). Mechanisms of enveloped RNA virus budding. Trends Cell Biol. 12, 569-579.
34. Pornillos, O., Higginson, D.S., Stray, K.M., Fisher, R.D., Garrus, J.E., Payne, M., He, G.P., Wang, H.E., Morham, S.G., and Sundquist, W.I. (2003). HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J. Cell Biol. 162, 425-434.
35. Raiborg, C., Bache, K.G., Gillooly, D., Madshus, I.H., Stang, E., and Stenmark, H. (2002). Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat. Cell Biol. 4, 394-398.
36. Raiborg, C., Bache, K.G., Mehlum, A., Stang, E., and Stenmark, H. (2001). Hrs recruits clathrin to early endosomes. EMBO J. 20, 5008-5021.
37. Schiestl, R.H., and Gietz, R.D. (1989). High efficiency transformation of intact cells using single stranded nucleic acid as a carrier. Curr. Genet. 16, 339-346.
38. Shih, S.C., Katzmann, D.J., Schnell, J.D., Sutanto, M., Emr, S.D., and Hicke, L. (2002). Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat. Cell Biol. 4, 389-393.
39. Simonsen, A., Bremnes, B., Rønning, E., Aasland, R., and Stenmark, H. (1998). Syntaxin-16, a putative Golgi t-SNARE. Eur. J. Cell Biol. 75, 223-231.
40. Vincent, O., Rainbow, L., Tilburn, J., Arst, H.N., Jr., and Penalva, M.A. (2003). YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix. Mol. Cell Biol. 23, 1647-1655.
41. Vojtek, A.B., Hollenberg, S.M., and Cooper, J.A. (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74, 205-214.
42. von Schwedler, U.K., et al. (2003). The protein network of HIV budding. Cell 114, 701-713.
43. Waterman, H., and Yarden, Y. (2001). Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases. FEBS Lett. 490, 142-152.
44. Xu, Z., Liang, L., Wang, H., Li, T., and Zhao, M. (2003). HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein. Biochem. Biophys. Res. Commun. 311, 1057-1066.