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Volumn 10, Issue 5, 2008, Pages 471-480

Decitabine-induced demethylation of 5′ CpG island in GADD45A leads to apoptosis in osteosarcoma cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; TRANSFER RNA;

EID: 43249116904     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.08174     Document Type: Article
Times cited : (50)

References (46)
  • 1
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone—modification maps
    • M Esteller Cancer epigenomics: DNA methylomes and histone—modification maps Nat Rev Genet 8 4 2007 286 298
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M1
  • 4
    • 0038747956 scopus 로고    scopus 로고
    • Relevance of DNA methylation in the management of cancer
    • M Esteller Relevance of DNA methylation in the management of cancer Lancet Oncol 4 6 2003 351 358
    • (2003) Lancet Oncol , vol.4 , Issue.6 , pp. 351-358
    • Esteller, M1
  • 5
    • 35348849607 scopus 로고    scopus 로고
    • Epigenetics provides a new generation of oncogenes and tumour-suppressor genes
    • M Esteller Epigenetics provides a new generation of oncogenes and tumour-suppressor genes Br J Cancer 96 Suppl 2007 R26 R30
    • (2007) Br J Cancer , vol.96 , Issue.Suppl , pp. R26-R30
    • Esteller, M1
  • 6
    • 34250213859 scopus 로고    scopus 로고
    • DNA methylation as a therapeutic target in cancer
    • JP Issa DNA methylation as a therapeutic target in cancer Clin Cancer Res 13 6 2007 1634 1637
    • (2007) Clin Cancer Res , vol.13 , Issue.6 , pp. 1634-1637
    • Issa, JP1
  • 7
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: the DNA hypermethylome
    • M Esteller Epigenetic gene silencing in cancer: the DNA hypermethylome Hum Mol Genet 16 2007 R50 R59 (Spec No 1)
    • (2007) Hum Mol Genet , vol.16 , pp. R50-R59
    • Esteller, M1
  • 8
    • 35448997854 scopus 로고    scopus 로고
    • Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: identification of apoptotic genes as targets for demethylation
    • KI Al-Romaih GR Somers J Bayani S Hughes M Prasad JC Cutz H Xue M Zielenska Y Wang JA Squire Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: identification of apoptotic genes as targets for demethylation Cancer Cell Int 7 1 2007 14
    • (2007) Cancer Cell Int , vol.7 , Issue.1 , pp. 14
    • Al-Romaih, KI1    Somers, GR2    Bayani, J3    Hughes, S4    Prasad, M5    Cutz, JC6    Xue, H7    Zielenska, M8    Wang, Y9    Squire, JA10
  • 9
    • 25144510121 scopus 로고    scopus 로고
    • The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors
    • J Ying G Srivastava WS Hsieh Z Gao P Murray SK Liao R Ambinder Q Tao The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors Clin Cancer Res 11 18 2005 6442 6449
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6442-6449
    • Ying, J1    Srivastava, G2    Hsieh, WS3    Gao, Z4    Murray, P5    Liao, SK6    Ambinder, R7    Tao, Q8
  • 10
    • 25144508812 scopus 로고    scopus 로고
    • GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets
    • LF Zerbini TA Libermann GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets Clin Cancer Res 11 18 2005 6409 6413
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6409-6413
    • Zerbini, LF1    Libermann, TA2
  • 12
    • 10444235646 scopus 로고    scopus 로고
    • Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage
    • Q Zhan Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage Mutat Res 569 1–2 2005 133 143
    • (2005) Mutat Res , vol.569 , Issue.1–2 , pp. 133-143
    • Zhan, Q1
  • 15
    • 0037048302 scopus 로고    scopus 로고
    • Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a
    • MC Hollander AJ Fornace Jr Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a Oncogene 21 40 2002 6228 6233
    • (2002) Oncogene , vol.21 , Issue.40 , pp. 6228-6233
    • Hollander, MC1    Fornace, AJ2
  • 19
    • 0141889935 scopus 로고    scopus 로고
    • High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays
    • JA Squire J Pei P Marrano B Beheshti J Bayani G Lim L Moldovan M Zielenska High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays Genes Chromosomes Cancer 38 3 2003 215 225
    • (2003) Genes Chromosomes Cancer , vol.38 , Issue.3 , pp. 215-225
    • Squire, JA1    Pei, J2    Marrano, P3    Beheshti, B4    Bayani, J5    Lim, G6    Moldovan, L7    Zielenska, M8
  • 20
    • 2442710134 scopus 로고    scopus 로고
    • c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism
    • D Barsyte-Lovejoy DY Mao LZ Penn c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism Oncogene 23 19 2004 3481 3486
    • (2004) Oncogene , vol.23 , Issue.19 , pp. 3481-3486
    • Barsyte-Lovejoy, D1    Mao, DY2    Penn, LZ3
  • 21
    • 33751179886 scopus 로고    scopus 로고
    • Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element
    • K Daino S Ichimura M Nenoi Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element Biochim Biophys Acta 1759 10 2006 458 469
    • (2006) Biochim Biophys Acta , vol.1759 , Issue.10 , pp. 458-469
    • Daino, K1    Ichimura, S2    Nenoi, M3
  • 22
    • 0032514967 scopus 로고    scopus 로고
    • A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
    • M Takekawa H Saito A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK Cell 95 4 1998 521 530
    • (1998) Cell , vol.95 , Issue.4 , pp. 521-530
    • Takekawa, M1    Saito, H2
  • 24
    • 21044444012 scopus 로고    scopus 로고
    • Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria
    • T Tong J Ji S Jin X Li W Fan Y Song M Wang Z Liu M Wu Q Zhan Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria Mol Cell Biol 25 11 2005 4488 4500
    • (2005) Mol Cell Biol , vol.25 , Issue.11 , pp. 4488-4500
    • Tong, T1    Ji, J2    Jin, S3    Li, X4    Fan, W5    Song, Y6    Wang, M7    Liu, Z8    Wu, M9    Zhan, Q10
  • 25
    • 17844395749 scopus 로고    scopus 로고
    • Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer
    • W Wang G Huper Y Guo SK Murphy JA Olson Jr JR Marks Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer Oncogene 24 16 2005 2705 2714
    • (2005) Oncogene , vol.24 , Issue.16 , pp. 2705-2714
    • Wang, W1    Huper, G2    Guo, Y3    Murphy, SK4    Olson, JA5    Marks, JR6
  • 26
    • 0036171225 scopus 로고    scopus 로고
    • Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine
    • G Liang FA Gonzales PA Jones TF Orntoft T Thykjaer Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine Cancer Res 62 4 2002 961 966
    • (2002) Cancer Res , vol.62 , Issue.4 , pp. 961-966
    • Liang, G1    Gonzales, FA2    Jones, PA3    Orntoft, TF4    Thykjaer, T5
  • 28
    • 20344361938 scopus 로고    scopus 로고
    • Development and characterization of efficient xenograft models for benign and malignant human prostate tissue
    • Y Wang MP Revelo D Sudilovsky M Cao WG Chen L Goetz H Xue M Sadar SB Shappell GR Cunha Development and characterization of efficient xenograft models for benign and malignant human prostate tissue Prostate 64 2 2005 149 159
    • (2005) Prostate , vol.64 , Issue.2 , pp. 149-159
    • Wang, Y1    Revelo, MP2    Sudilovsky, D3    Cao, M4    Chen, WG5    Goetz, L6    Xue, H7    Sadar, M8    Shappell, SB9    Cunha, GR10
  • 29
    • 0345603004 scopus 로고    scopus 로고
    • The CpG island searcher: a new WWW resource
    • D Takai PA Jones The CpG island searcher: a new WWW resource In Silico Biol 3 3 2003 235 240
    • (2003) In Silico Biol , vol.3 , Issue.3 , pp. 235-240
    • Takai, D1    Jones, PA2
  • 32
    • 0031014589 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for pediatric osteosarcoma patients
    • A Uchida A Myoui N Araki H Yoshikawa Y Shinto T Ueda Neoadjuvant chemotherapy for pediatric osteosarcoma patients Cancer 79 2 1997 411 415
    • (1997) Cancer , vol.79 , Issue.2 , pp. 411-415
    • Uchida, A1    Myoui, A2    Araki, N3    Yoshikawa, H4    Shinto, Y5    Ueda, T6
  • 34
    • 0030605691 scopus 로고    scopus 로고
    • Preoperative and postoperative chemotherapy of osteogenic sarcoma of the limbs in children
    • Villa A Munoz G Ocete ML Aymerich S Maldonado E Otheo M Calvo J Amaya Preoperative and postoperative chemotherapy of osteogenic sarcoma of the limbs in children Med Clin (Barc) 107 5 1996 161 164
    • (1996) Med Clin (Barc) , vol.107 , Issue.5 , pp. 161-164
    • Munoz, Villa A1    Ocete, G2    Aymerich, ML3    Maldonado, S4    Otheo, E5    Calvo, M6    Amaya, J7
  • 36
    • 34548585368 scopus 로고    scopus 로고
    • The use of hypomethylating agents in the treatment of hematologic malignancies
    • JE Kihslinger LA Godley The use of hypomethylating agents in the treatment of hematologic malignancies Leuk Lymphoma 48 9 2007 1676 1695
    • (2007) Leuk Lymphoma , vol.48 , Issue.9 , pp. 1676-1695
    • Kihslinger, JE1    Godley, LA2
  • 37
    • 0035866787 scopus 로고    scopus 로고
    • Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency
    • MC Hollander O Kovalsky JM Salvador KE Kim AD Patterson DC Haines AJ Fornace Jr Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency Cancer Res 61 6 2001 2487 2491
    • (2001) Cancer Res , vol.61 , Issue.6 , pp. 2487-2491
    • Hollander, MC1    Kovalsky, O2    Salvador, JM3    Kim, KE4    Patterson, AD5    Haines, DC6    Fornace, AJ7
  • 40
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • M Kansara DM Thomas Molecular pathogenesis of osteosarcoma DNA Cell Biol 26 1 2007 1 18
    • (2007) DNA Cell Biol , vol.26 , Issue.1 , pp. 1-18
    • Kansara, M1    Thomas, DM2
  • 41
    • 0036275374 scopus 로고    scopus 로고
    • Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
    • H Mita J Tsutsui M Takekawa EA Witten H Saito Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding Mol Cell Biol 22 13 2002 4544 4555
    • (2002) Mol Cell Biol , vol.22 , Issue.13 , pp. 4544-4555
    • Mita, H1    Tsutsui, J2    Takekawa, M3    Witten, EA4    Saito, H5
  • 42
    • 33749023927 scopus 로고    scopus 로고
    • Gadd45a suppresses Rasdriven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence
    • JS Tront B Hoffman DA Liebermann Gadd45a suppresses Rasdriven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence Cancer Res 66 17 2006 8448 8454
    • (2006) Cancer Res , vol.66 , Issue.17 , pp. 8448-8454
    • Tront, JS1    Hoffman, B2    Liebermann, DA3
  • 43
    • 0037115421 scopus 로고    scopus 로고
    • Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53
    • J Hildesheim DV Bulavin MR Anver WG Alvord MC Hollander L Vardanian AJ Fornace Jr Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53 Cancer Res 62 24 2002 7305 7315
    • (2002) Cancer Res , vol.62 , Issue.24 , pp. 7305-7315
    • Hildesheim, J1    Bulavin, DV2    Anver, MR3    Alvord, WG4    Hollander, MC5    Vardanian, L6    Fornace, AJ7
  • 44
    • 33845946480 scopus 로고    scopus 로고
    • Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses
    • D Zhang L Song J Li K Wu C Huang Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses J Biol Chem 281 45 2006 34113 34123
    • (2006) J Biol Chem , vol.281 , Issue.45 , pp. 34113-34123
    • Zhang, D1    Song, L2    Li, J3    Wu, K4    Huang, C5
  • 45
    • 34247511439 scopus 로고    scopus 로고
    • Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells
    • J Yamauchi Y Miyamoto M Murabe Y Fujiwara A Sanbe Y Fujita S Murase A Tanoue Gadd45a , the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells Exp Cell Res 313 9 2007 1886 1896
    • (2007) Exp Cell Res , vol.313 , Issue.9 , pp. 1886-1896
    • Yamauchi, J1    Miyamoto, Y2    Murabe, M3    Fujiwara, Y4    Sanbe, A5    Fujita, Y6    Murase, S7    Tanoue, A8
  • 46
    • 4344633830 scopus 로고    scopus 로고
    • High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalin-fixed paraffin-embedded tissue
    • M Zielenska P Marrano P Thorner J Pei B Beheshti M Ho J Bayani Y Liu BC Sun JA Squire High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalin-fixed paraffin-embedded tissue Cytogenet Genome Res 107 1–2 2004 77 82
    • (2004) Cytogenet Genome Res , vol.107 , Issue.1–2 , pp. 77-82
    • Zielenska, M1    Marrano, P2    Thorner, P3    Pei, J4    Beheshti, B5    Ho, M6    Bayani, J7    Liu, Y8    Sun, BC9    Squire, JA10


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