Peptide-based in vitro assay for the detection of reactive metabolites

Chemical Research in Toxicology

Volumn 21, Issue 4, 2008, Pages 859-868

  Mitchell, Michael D ^a   Elrick, Mollisa M ^a   Walgren, Jennie L ^a   Mueller, Richard A ^b   Morris, Dale L ^a   Thompson, David C ^a  

^a PFIZER INC   (United States)

^b ChemGate Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; AMINO ACID; CYSTEINE; CYTOCHROME P450; PEPTIDE;

ANIMAL CELL; ARTICLE; ASSAY; CATION EXCHANGE; COVALENT BOND; DRUG ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER MICROSOME; METABOLITE; NONHUMAN; PROTEIN BINDING; RAT; TIME OF FLIGHT MASS SPECTROMETRY;

ALDEHYDE DEHYDROGENASE; ANIMALS; BIOLOGICAL ASSAY; BIOTRANSFORMATION; CYTOCHROME P-450 CYP3A; HORSERADISH PEROXIDASE; HUMANS; MICROSOMES, LIVER; PEPTIDES; PEROXIDASE; RATS; RECOMBINANT PROTEINS;

RATTUS;

EID: 43149125196     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx700344m     Document Type: Article

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