Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen

Vaccine

Volumn 26, Issue 22, 2008, Pages 2680-2688

  Mutwiri, George ^a   Benjamin, Ponn ^a   Soita, Henry ^a   Babiuk, Lorne A ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Adjuvants; CpG ODN; HBsAg; PCEP; PCPP; Polyphosphazenes; Vaccines

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 12; INTERLEUKIN 4; POLY[DI(SODIUM CARBOXYLATOETHYLPHENOXY)PHOSPHAZENE]; POLY[DI(SODIUM CARBOXYLATOPHENOXY)PHOSPHAZENE];

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG FORMULATION; DRUG POTENTIATION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOSTIMULATION; INNATE IMMUNITY; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SPLEEN CELL; TH1 CELL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELLS, CULTURED; DRUG SYNERGISM; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; IMMUNOGLOBULIN G; INJECTIONS, SUBCUTANEOUS; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; OLIGODEOXYRIBONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS;

EID: 43049176766     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.03.031     Document Type: Article

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