Synthetic retinoid CD437 induces mitochondria-mediated apoptosis in hepatocellular carcinoma cells

Biochemical and Biophysical Research Communications

Volumn 370, Issue 4, 2008, Pages 629-633

  Gonda, Kazue ^a   Tsuchiya, Hiroyuki ^a   Sakabe, Tomohiko ^a   Akechi, Yuji ^a   Ikeda, Remina ^a   Nishio, Ren ^a   Terabayashi, Kei ^a   Ishii, Kyoko ^a   Matsumi, Yoshiaki ^a   Ashla, An Afida ^a   Okamoto, Hideharu ^b   Takubo, Kazuko ^b   Matsuoka, Saori ^a,c   Watanabe, Yumi ^a,d   Hoshikawa, Yoshiko ^a   Kurimasa, Akihiro ^a   Shiota, Goshi ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c SHIMANE PREFECTURAL CENTRAL HOSPITAL   (Japan)

^d Watanabe Children and Ladies Clinic   (Japan)

Author keywords

Apoptosis; CD437; Hepatocellular carcinoma; Mitochondria; Synthetic retinoid

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; CASPASE 3; CASPASE 9; PROTEIN BAX; PROTEIN BCL 2; RETINOID DERIVATIVE; RHODAMINE 123;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MEMBRANE DEPOLARIZATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RETINOIDS;

EID: 43049176639     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.008     Document Type: Article

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