-
1
-
-
0344301900
-
Role of the p16 tumor suppressor gene in cancer
-
Liggett Jr. W.H., and Sidransky D. Role of the p16 tumor suppressor gene in cancer. J Clin Oncol 16 (1998) 1197-1206
-
(1998)
J Clin Oncol
, vol.16
, pp. 1197-1206
-
-
Liggett Jr., W.H.1
Sidransky, D.2
-
2
-
-
0030941813
-
Homozygous deletion of the p16/MTS1 gene in pediatric acute lymphoblastic leukemia is associated with unfavorable clinical outcome
-
Kees U.R., Burton P.R., Lu C., and Baker D.L. Homozygous deletion of the p16/MTS1 gene in pediatric acute lymphoblastic leukemia is associated with unfavorable clinical outcome. Blood 89 (1997) 4161-4166
-
(1997)
Blood
, vol.89
, pp. 4161-4166
-
-
Kees, U.R.1
Burton, P.R.2
Lu, C.3
Baker, D.L.4
-
3
-
-
0036799357
-
Deletion of the Ink4-locus (the p16ink4a, p14ARF and p15ink4b genes) predicts relapse in children with ALL treated according to the Nordic protocols NOPHO-86 and NOPHO-92
-
Calero Moreno T.M., Gustafsson G., Garwicz S., Grander D., Jonmundsson G.K., Frost B.M., et al. Deletion of the Ink4-locus (the p16ink4a, p14ARF and p15ink4b genes) predicts relapse in children with ALL treated according to the Nordic protocols NOPHO-86 and NOPHO-92. Leukemia 16 (2002) 2037-2045
-
(2002)
Leukemia
, vol.16
, pp. 2037-2045
-
-
Calero Moreno, T.M.1
Gustafsson, G.2
Garwicz, S.3
Grander, D.4
Jonmundsson, G.K.5
Frost, B.M.6
-
4
-
-
37849189808
-
Application of high throughput cell array technology to FISH: investigation of the role of deletion of p16 gene in leukemias
-
Lee D.S., Lee J.H., Min H.C., Kim T.Y., Oh B.R., Kim H.Y., et al. Application of high throughput cell array technology to FISH: investigation of the role of deletion of p16 gene in leukemias. J Biotechnol 127 (2007) 355-360
-
(2007)
J Biotechnol
, vol.127
, pp. 355-360
-
-
Lee, D.S.1
Lee, J.H.2
Min, H.C.3
Kim, T.Y.4
Oh, B.R.5
Kim, H.Y.6
-
5
-
-
0029664370
-
Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia
-
Heyman M., Rasool O., Borgonovo Brandter L., Liu Y., Grander D., Soderhall S., et al. Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia. J Clin Oncol 14 (1996) 1512-1520
-
(1996)
J Clin Oncol
, vol.14
, pp. 1512-1520
-
-
Heyman, M.1
Rasool, O.2
Borgonovo Brandter, L.3
Liu, Y.4
Grander, D.5
Soderhall, S.6
-
6
-
-
34249733805
-
High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
-
Kuiper R.P., Schoenmakers E.F., van Reijmersdal S.V., Hehir-Kwa J.Y., van Kessel A.G., van Leeuwen F.N., et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia 21 (2007) 1258-1266
-
(2007)
Leukemia
, vol.21
, pp. 1258-1266
-
-
Kuiper, R.P.1
Schoenmakers, E.F.2
van Reijmersdal, S.V.3
Hehir-Kwa, J.Y.4
van Kessel, A.G.5
van Leeuwen, F.N.6
-
7
-
-
33745781461
-
The prognostic significance of CDKN2A, CDKN2B and MTAP inactivation in B-lineage acute lymphoblastic leukemia of childhood. Results of the EORTC studies 58881 and 58951
-
Mirebeau D., Acquaviva C., Suciu S., Bertin R., Dastugue N., Robert A., et al. The prognostic significance of CDKN2A, CDKN2B and MTAP inactivation in B-lineage acute lymphoblastic leukemia of childhood. Results of the EORTC studies 58881 and 58951. Haematologica 91 (2006) 881-885
-
(2006)
Haematologica
, vol.91
, pp. 881-885
-
-
Mirebeau, D.1
Acquaviva, C.2
Suciu, S.3
Bertin, R.4
Dastugue, N.5
Robert, A.6
-
8
-
-
17144422895
-
Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis
-
Irving J.A., Bloodworth L., Bown N.P., Case M.C., Hogarth L.A., and Hall A.G. Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis. Cancer Res 65 (2005) 3053-3058
-
(2005)
Cancer Res
, vol.65
, pp. 3053-3058
-
-
Irving, J.A.1
Bloodworth, L.2
Bown, N.P.3
Case, M.C.4
Hogarth, L.A.5
Hall, A.G.6
-
9
-
-
21744454690
-
CDKN2 deletions have no prognostic value in childhood precursor-B acute lymphoblastic leukaemia
-
van Zutven L.J., van Drunen E., de Bont J.M., Wattel M.M., Den Boer M.L., Pieters R., et al. CDKN2 deletions have no prognostic value in childhood precursor-B acute lymphoblastic leukaemia. Leukemia 19 (2005) 1281-1284
-
(2005)
Leukemia
, vol.19
, pp. 1281-1284
-
-
van Zutven, L.J.1
van Drunen, E.2
de Bont, J.M.3
Wattel, M.M.4
Den Boer, M.L.5
Pieters, R.6
-
10
-
-
0037402496
-
CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono- and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia
-
Bertin R., Acquaviva C., Mirebeau D., Guidal-Giroux C., Vilmer E., and Cave H. CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono- and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer 37 (2003) 44-57
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 44-57
-
-
Bertin, R.1
Acquaviva, C.2
Mirebeau, D.3
Guidal-Giroux, C.4
Vilmer, E.5
Cave, H.6
-
11
-
-
0029121279
-
Homozygous deletions of p16/MTS1 gene are frequent but mutations are infrequent in childhood T-cell acute lymphoblastic leukemia
-
Ohnishi H., Kawamura M., Ida K., Sheng X.M., Hanada R., Nobori T., et al. Homozygous deletions of p16/MTS1 gene are frequent but mutations are infrequent in childhood T-cell acute lymphoblastic leukemia. Blood 86 (1995) 1269-1275
-
(1995)
Blood
, vol.86
, pp. 1269-1275
-
-
Ohnishi, H.1
Kawamura, M.2
Ida, K.3
Sheng, X.M.4
Hanada, R.5
Nobori, T.6
-
12
-
-
34249668665
-
Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization
-
Strefford J.C., Worley H., Barber K., Wright S., Stewart A.R., Robinson H.M., et al. Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization. Oncogene 26 (2007) 4306-4318
-
(2007)
Oncogene
, vol.26
, pp. 4306-4318
-
-
Strefford, J.C.1
Worley, H.2
Barber, K.3
Wright, S.4
Stewart, A.R.5
Robinson, H.M.6
-
13
-
-
0029054399
-
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
-
Lukas J., Parry D., Aagaard L., Mann D.J., Bartkova J., Strauss M., et al. Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature 375 (1995) 503-506
-
(1995)
Nature
, vol.375
, pp. 503-506
-
-
Lukas, J.1
Parry, D.2
Aagaard, L.3
Mann, D.J.4
Bartkova, J.5
Strauss, M.6
-
14
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott F.J., Bates S., James M.C., McConnell B.B., Starborg M., Brookes S., et al. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J 17 (1998) 5001-5014
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
-
15
-
-
85047700405
-
Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways
-
Weber H.O., Samuel T., Rauch P., and Funk J.O. Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways. Oncogene 21 (2002) 3207-3212
-
(2002)
Oncogene
, vol.21
, pp. 3207-3212
-
-
Weber, H.O.1
Samuel, T.2
Rauch, P.3
Funk, J.O.4
-
16
-
-
0028168242
-
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
-
Hannon G.J., and Beach D. p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 371 (1994) 257-261
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
17
-
-
13044266372
-
Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group
-
Heerema N.A., Sather H.N., Sensel M.G., Liu-Mares W., Lange B.J., Bostrom B.C., et al. Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood 94 (1999) 1537-1544
-
(1999)
Blood
, vol.94
, pp. 1537-1544
-
-
Heerema, N.A.1
Sather, H.N.2
Sensel, M.G.3
Liu-Mares, W.4
Lange, B.J.5
Bostrom, B.C.6
-
18
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A., Herman J.G., Mao L., Lee D.J., Gabrielson E., Burger P.C., et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1 (1995) 686-692
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
-
19
-
-
0035876192
-
Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance
-
Chim C.S., Tam C.Y., Liang R., and Kwong Y.L. Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance. Cancer 91 (2001) 2222-2229
-
(2001)
Cancer
, vol.91
, pp. 2222-2229
-
-
Chim, C.S.1
Tam, C.Y.2
Liang, R.3
Kwong, Y.L.4
-
20
-
-
0030031325
-
Deletion mapping indicates that MTS1 is the target of frequent deletions at chromosome 9p21 in paediatric acute lymphoblastic leukaemias
-
Guidal-Giroux C., Gerard B., Cave H., Duval M., Rohrlich P., Elion J., et al. Deletion mapping indicates that MTS1 is the target of frequent deletions at chromosome 9p21 in paediatric acute lymphoblastic leukaemias. Br J Haematol 92 (1996) 410-419
-
(1996)
Br J Haematol
, vol.92
, pp. 410-419
-
-
Guidal-Giroux, C.1
Gerard, B.2
Cave, H.3
Duval, M.4
Rohrlich, P.5
Elion, J.6
-
21
-
-
37549039470
-
Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH analysis of Ewing sarcoma
-
Savola S., Nardi F., Scotlandi K., Picci P., and Knuutila S. Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH analysis of Ewing sarcoma. Cytogenet Genome Res 119 1-2 (2007) 21-26
-
(2007)
Cytogenet Genome Res
, vol.119
, Issue.1-2
, pp. 21-26
-
-
Savola, S.1
Nardi, F.2
Scotlandi, K.3
Picci, P.4
Knuutila, S.5
-
22
-
-
0038185593
-
Improving outcome through two decades in childhood ALL in the Nordic countries: the impact of high-dose methotrexate in the reduction of CNS irradiation. Nordic Society of Pediatric Haematology and Oncology (NOPHO)
-
Gustafsson G., Schmiegelow K., Forestier E., Clausen N., Glomstein A., Jonmundsson G., et al. Improving outcome through two decades in childhood ALL in the Nordic countries: the impact of high-dose methotrexate in the reduction of CNS irradiation. Nordic Society of Pediatric Haematology and Oncology (NOPHO). Leukemia 14 (2000) 2267-2275
-
(2000)
Leukemia
, vol.14
, pp. 2267-2275
-
-
Gustafsson, G.1
Schmiegelow, K.2
Forestier, E.3
Clausen, N.4
Glomstein, A.5
Jonmundsson, G.6
-
23
-
-
10744233834
-
Outcome of children with high-risk acute lymphoblastic leukemia (HR-ALL): nordic results on an intensive regimen with restricted central nervous system irradiation
-
Saarinen-Pihkala U.M., Gustafsson G., Carlsen N., Flaegstad T., Forestier E., Glomstein A., et al. Outcome of children with high-risk acute lymphoblastic leukemia (HR-ALL): nordic results on an intensive regimen with restricted central nervous system irradiation. Pediatr Blood Cancer 42 (2004) 8-23
-
(2004)
Pediatr Blood Cancer
, vol.42
, pp. 8-23
-
-
Saarinen-Pihkala, U.M.1
Gustafsson, G.2
Carlsen, N.3
Flaegstad, T.4
Forestier, E.5
Glomstein, A.6
-
24
-
-
33847391188
-
Loss of TP53 in sarcomas with 17p12 to approximately p11 gain. A fine-resolution oligonucleotide array comparative genomic hybridization study
-
Kaur S., Larramendy M.L., Vauhkonen H., Bohling T., and Knuutila S. Loss of TP53 in sarcomas with 17p12 to approximately p11 gain. A fine-resolution oligonucleotide array comparative genomic hybridization study. Cytogenet Genome Res 116 (2007) 153-157
-
(2007)
Cytogenet Genome Res
, vol.116
, pp. 153-157
-
-
Kaur, S.1
Larramendy, M.L.2
Vauhkonen, H.3
Bohling, T.4
Knuutila, S.5
-
25
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan E., and Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 53 457 (1958) 458-481
-
(1958)
J Am Stat Assoc
, vol.53
, Issue.457
, pp. 458-481
-
-
Kaplan, E.1
Meier, P.2
-
26
-
-
0017365573
-
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
-
Peto R., Pike M.C., Armitage P., Breslow N.E., Cox D.R., Howard S.V., et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 35 (1977) 1-39
-
(1977)
Br J Cancer
, vol.35
, pp. 1-39
-
-
Peto, R.1
Pike, M.C.2
Armitage, P.3
Breslow, N.E.4
Cox, D.R.5
Howard, S.V.6
-
27
-
-
0030929534
-
Detection of p16 gene deletions in gliomas: a comparison of fluorescence in situ hybridization (FISH) versus quantitative PCR
-
Perry A., Nobori T., Ru N., Anderl K., Borell T.J., Mohapatra G., et al. Detection of p16 gene deletions in gliomas: a comparison of fluorescence in situ hybridization (FISH) versus quantitative PCR. J Neuropathol Exp Neurol 56 (1997) 999-1008
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 999-1008
-
-
Perry, A.1
Nobori, T.2
Ru, N.3
Anderl, K.4
Borell, T.J.5
Mohapatra, G.6
-
28
-
-
0029029358
-
Detection of homozygous deletions of the cyclin-dependent kinase 4 inhibitor (p16) gene in acute lymphoblastic leukemia and association with adverse prognostic features
-
Fizzotti M., Cimino G., Pisegna S., Alimena G., Quartarone C., Mandelli F., et al. Detection of homozygous deletions of the cyclin-dependent kinase 4 inhibitor (p16) gene in acute lymphoblastic leukemia and association with adverse prognostic features. Blood 85 (1995) 2685-2690
-
(1995)
Blood
, vol.85
, pp. 2685-2690
-
-
Fizzotti, M.1
Cimino, G.2
Pisegna, S.3
Alimena, G.4
Quartarone, C.5
Mandelli, F.6
-
29
-
-
20044367805
-
Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse
-
Huang H.Y., Illei P.B., Zhao Z., Mazumdar M., Huvos A.G., Healey J.H., et al. Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse. J Clin Oncol 23 (2005) 548-558
-
(2005)
J Clin Oncol
, vol.23
, pp. 548-558
-
-
Huang, H.Y.1
Illei, P.B.2
Zhao, Z.3
Mazumdar, M.4
Huvos, A.G.5
Healey, J.H.6
-
30
-
-
29744463936
-
Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis
-
Oda Y., Yamamoto H., Takahira T., Kobayashi C., Kawaguchi K., Tateishi N., et al. Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis. J Pathol 207 (2005) 410-421
-
(2005)
J Pathol
, vol.207
, pp. 410-421
-
-
Oda, Y.1
Yamamoto, H.2
Takahira, T.3
Kobayashi, C.4
Kawaguchi, K.5
Tateishi, N.6
-
31
-
-
0019410724
-
The morphological classification of acute lymphoblastic leukaemia: concordance among observers and clinical correlations
-
Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., et al. The morphological classification of acute lymphoblastic leukaemia: concordance among observers and clinical correlations. Br J Haematol 47 (1981) 553-561
-
(1981)
Br J Haematol
, vol.47
, pp. 553-561
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
Flandrin, G.4
Galton, D.A.5
Gralnick, H.R.6
-
32
-
-
0017162163
-
Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group
-
Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 33 (1976) 451-458
-
(1976)
Br J Haematol
, vol.33
, pp. 451-458
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
Flandrin, G.4
Galton, D.A.5
Gralnick, H.R.6
|