Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis

Cancer Research

Volumn 65, Issue 8, 2005, Pages 3053-3058

  Irving, Julie A E ^a   Bloodworth, Lisa ^a   Bown, Nick P ^a   Case, Marian C ^a   Hogarth, Linda A ^a   Hall, Andrew G ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; ETOPOSIDE; GLUCOCORTICOID RECEPTOR; PROTEIN P16INK4A; STEROID;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLELE; ARTICLE; CANCER GROWTH; CANCER RECURRENCE; CANCER RELAPSE; CAUSE OF DEATH; CELL ISOLATION; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 9P; CHROMOSOME ABERRATION; CLINICAL ARTICLE; DNA MICROARRAY; GENE LOCUS; GENE LOSS; GENE MAPPING; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LYMPHOBLAST; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT FAILURE;

EID: 17144422895     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-2604     Document Type: Article

References (14)

1. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998;396:643-9.
2. Matsuzaki H, Loi H, Dong S, et al. Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array. Genome Res 2004;14:414-25.
3. Wong KK, Tsang YT, Shen J, et al. Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA. Nucleic Acids Res 2004;32:e69.
4. Takeuchi S, Seriu T, van Dongen JJ, et al. Allelotype analysis in relapsed childhood acute lymphoblastic leukemia. Oncogene 2003;22:6970-6.
5. Calero Moreno TM, Gustafsson G, Garwicz S, et al. Deletion of the Ink4-locus (the p16ink4a, p14ARF and p15ink4b genes) predicts relapse in children with ALL treated according to the Nordic protocols NOPHO-86 and NOPHO-92. Leukemia 2002;16:2037-45.
6. Hann I, Vora A, Harrison G, et al. Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol. Br J Haematol 2001;113:103-14.
7. Scholz I, Popp S, Granzow M, et al. Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis. Cancer Genet Cytogenet 2001;124:89-97.
8. Heerema NA, Sather HN, Sensel MG, et al. Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood 1999;94:1537-44.
9. Yasui K, Mihara S, Zhao C, et al. Alteration in copy numbers of genes as a mechanism for acquired drug resistance. Cancer Res 2004;64:1403-14.
10. Clark R, Byatt SA, Bennett CF, et al. Monosomy 20 as a pointer to dicentric (9;20) in acute lymphoblastic leukemia. Leukemia 2000;14:241-6.
11. McEvoy CR, Morley AA, Firgaira FA. Evidence for whole chromosome 6 loss and duplication of the remaining chromosome in acute lymphoblastic leukemia. Genes Chromosomes Cancer 2003;37:321-5.
12. Takeuchi S, Tsukasaki K, Bartram CR, et al. Long-term study of the clinical significance of loss of heterozygosity in childhood acute lymphoblastic leukemia. Leukemia 2003;17:149-54.
13. Kristensen TD, Wesenberg F, Jonsson OG, et al. High-resolution comparative genomic hybridisation yields a high detection rate of chromosomal aberrations in childhood acute lymphoblastic leukaemia. Eur J Haematol 2003;70:363-72.
14. Kirchhoff M, Gerdes T, Maahr J, et al. Deletions below 10 megabasepairs are detected in comparative genomic hybridization by standard reference intervals. Genes Chromosomes Cancer 1999;25:410-3.