메뉴 건너뛰기




Volumn 68, Issue 7, 2008, Pages 698-714

Longitudinal analysis of androgen deprivation of prostate cancer cells identifies pathways to androgen independence

Author keywords

Androgen ablation; Androgen independent prostate cancer; Gene expression array; Survival

Indexed keywords

ANDROGEN; ANDROGEN METABOLIZING ENZYME; ANDROGEN RECEPTOR; BIOLOGICAL MARKER; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOCHROME C; E1A PROTEIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENZYME; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GELSOLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JAGGED1; MATRILYSIN; NUCLEAR RECEPTOR COACTIVATOR 2; NUCLEAR RECEPTOR COREPRESSOR; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; PROTEIN P53; SCATTER FACTOR RECEPTOR; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; SONIC HEDGEHOG PROTEIN; STEROID RECEPTOR COACTIVATOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNINDEXED DRUG;

EID: 43049131149     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20677     Document Type: Article
Times cited : (43)

References (55)
  • 2
    • 0024832529 scopus 로고
    • Etiology and disease process of benign prostatic hyperplasia
    • Isaacs JT, Coffey DS. Etiology and disease process of benign prostatic hyperplasia. Prostate Suppl 1989;2:33-50.
    • (1989) Prostate Suppl , vol.2 , pp. 33-50
    • Isaacs, J.T.1    Coffey, D.S.2
  • 3
    • 0029873670 scopus 로고    scopus 로고
    • Denmeade SR, Lin XS, Isaacs JT. Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. [Erratum appears in Prostate 1996 Jun;28(6):414]. Prostate 1996;28(4):251-265.
    • Denmeade SR, Lin XS, Isaacs JT. Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. [Erratum appears in Prostate 1996 Jun;28(6):414]. Prostate 1996;28(4):251-265.
  • 4
    • 0032933296 scopus 로고    scopus 로고
    • The biology of hormone refractory prostate cancer. Why does it develop?
    • Isaacs JT. The biology of hormone refractory prostate cancer. Why does it develop? Urol Clin North Am 1999;26(2):263-273.
    • (1999) Urol Clin North Am , vol.26 , Issue.2 , pp. 263-273
    • Isaacs, J.T.1
  • 5
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1(1):34-45.
    • (2001) Nat Rev Cancer , vol.1 , Issue.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 6
    • 23244454378 scopus 로고    scopus 로고
    • Endothelin-1 inhibits apoptosis in prostate cancer
    • Nelson JB, Udan MS, Guruli G, Pflug BR. Endothelin-1 inhibits apoptosis in prostate cancer. Neoplasia 2005;7(7):631-637.
    • (2005) Neoplasia , vol.7 , Issue.7 , pp. 631-637
    • Nelson, J.B.1    Udan, M.S.2    Guruli, G.3    Pflug, B.R.4
  • 7
    • 24944494039 scopus 로고    scopus 로고
    • Role of endothelin axis in progression to aggressive phenotype of prostate adenocarcinoma
    • Godara G, Cannon GW, Cannon GM Jr, Bies RR, Nelson JB, Pflug BR. Role of endothelin axis in progression to aggressive phenotype of prostate adenocarcinoma. Prostate 2005;65(1):27-34.
    • (2005) Prostate , vol.65 , Issue.1 , pp. 27-34
    • Godara, G.1    Cannon, G.W.2    Cannon Jr, G.M.3    Bies, R.R.4    Nelson, J.B.5    Pflug, B.R.6
  • 8
    • 0032806788 scopus 로고    scopus 로고
    • Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines
    • Pflug BR, Reiter RE, Nelson JB. Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines. Prostate 1999;40(4):269-273.
    • (1999) Prostate , vol.40 , Issue.4 , pp. 269-273
    • Pflug, B.R.1    Reiter, R.E.2    Nelson, J.B.3
  • 9
    • 33744549560 scopus 로고    scopus 로고
    • In vitro transcription amplification and labeling methods contribute to the variability of gene expression profiling with DNA microarrays
    • Ma C, Lyons-Weiler M, Liang W, LaFramboise W, Gilbertson JR, Becich MJ, Monzon FA. In vitro transcription amplification and labeling methods contribute to the variability of gene expression profiling with DNA microarrays. J Mol Diagn 2006;8(2):183-192.
    • (2006) J Mol Diagn , vol.8 , Issue.2 , pp. 183-192
    • Ma, C.1    Lyons-Weiler, M.2    Liang, W.3    LaFramboise, W.4    Gilbertson, J.R.5    Becich, M.J.6    Monzon, F.A.7
  • 12
    • 0029859580 scopus 로고    scopus 로고
    • Human prostate tumor growth in athymic mice: Inhibition by androgens and stimulation by finasteride
    • Umekita Y, Hiipakka RA, Kokontis JM, Liao S. Human prostate tumor growth in athymic mice: Inhibition by androgens and stimulation by finasteride. Proc Natl Acad Sci USA 1996;93(21): 11802-11807.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.21 , pp. 11802-11807
    • Umekita, Y.1    Hiipakka, R.A.2    Kokontis, J.M.3    Liao, S.4
  • 14
    • 28744456066 scopus 로고    scopus 로고
    • Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity
    • Kokontis JM, Hsu S, Chuu CP, Dang M, Fukuchi J, Hiipakka RA, Liao S. Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity. Prostate 2005;65(4):287-298.
    • (2005) Prostate , vol.65 , Issue.4 , pp. 287-298
    • Kokontis, J.M.1    Hsu, S.2    Chuu, C.P.3    Dang, M.4    Fukuchi, J.5    Hiipakka, R.A.6    Liao, S.7
  • 15
    • 0242624620 scopus 로고    scopus 로고
    • Biologic and therapeutic role of HER2 in cancer
    • Menard S, Pupa SM, Campiglio M, Tagliabue E. Biologic and therapeutic role of HER2 in cancer. Oncogene 2003;22(42):6570-6578.
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6570-6578
    • Menard, S.1    Pupa, S.M.2    Campiglio, M.3    Tagliabue, E.4
  • 16
    • 33748769249 scopus 로고    scopus 로고
    • Pretreatment serum level of HER2/nue as a prognostic factor in metastatic prostate cancer patients about to undergo endocrine therapy
    • Okegawa T, Kinjo M, Nutahara K, Higashihara E. Pretreatment serum level of HER2/nue as a prognostic factor in metastatic prostate cancer patients about to undergo endocrine therapy. Int J Urol 2006;13(9):1197-1201.
    • (2006) Int J Urol , vol.13 , Issue.9 , pp. 1197-1201
    • Okegawa, T.1    Kinjo, M.2    Nutahara, K.3    Higashihara, E.4
  • 17
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
    • Daub H, Weiss FU, Wallasch C, Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996;379(6565):557-560.
    • (1996) Nature , vol.379 , Issue.6565 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ullrich, A.4
  • 18
    • 0034665584 scopus 로고    scopus 로고
    • Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells
    • Vacca F, Bagnato A, Catt KJ, Tecce R. Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells. Cancer Res 2000;60(18):5310-5317.
    • (2000) Cancer Res , vol.60 , Issue.18 , pp. 5310-5317
    • Vacca, F.1    Bagnato, A.2    Catt, K.J.3    Tecce, R.4
  • 19
    • 7944234374 scopus 로고    scopus 로고
    • HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
    • Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell 2004;6(5):517-527.
    • (2004) Cancer Cell , vol.6 , Issue.5 , pp. 517-527
    • Mellinghoff, I.K.1    Vivanco, I.2    Kwon, A.3    Tran, C.4    Wongvipat, J.5    Sawyers, C.L.6
  • 20
    • 0038637317 scopus 로고    scopus 로고
    • Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?
    • Litvinov IV, De Marzo AM, Isaacs JT. Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling? J Clin Endocrinol Metab 2003;88(7):2972-2982.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.7 , pp. 2972-2982
    • Litvinov, I.V.1    De Marzo, A.M.2    Isaacs, J.T.3
  • 21
    • 0033381357 scopus 로고    scopus 로고
    • The role for transforming growth factor-beta (TGF-beta) in human cancer
    • Gold LI. The role for transforming growth factor-beta (TGF-beta) in human cancer. Crit Rev Oncog 1999;10(4):303-360.
    • (1999) Crit Rev Oncog , vol.10 , Issue.4 , pp. 303-360
    • Gold, L.I.1
  • 25
    • 33748872289 scopus 로고    scopus 로고
    • Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells
    • Zhang Y, Wang Z, Ahmed F, Banerjee S, Li Y, Sarkar FH. Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells. Int J Cancer 2006;119(9): 2071-2077.
    • (2006) Int J Cancer , vol.119 , Issue.9 , pp. 2071-2077
    • Zhang, Y.1    Wang, Z.2    Ahmed, F.3    Banerjee, S.4    Li, Y.5    Sarkar, F.H.6
  • 27
    • 33645083201 scopus 로고    scopus 로고
    • Sonic Hedgehog signaling in advanced prostate cancer
    • Datta S, Datta MW. Sonic Hedgehog signaling in advanced prostate cancer. Cell Mol Life Sci 2006;63(4):435-448.
    • (2006) Cell Mol Life Sci , vol.63 , Issue.4 , pp. 435-448
    • Datta, S.1    Datta, M.W.2
  • 28
    • 30344480772 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis
    • Maywood
    • Ii M, Yamamoto H, Adachi Y, Maruyama Y, Shinomura Y. Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Exp Biol Med (Maywood) 2006;231(1):20-27.
    • (2006) Exp Biol Med , vol.231 , Issue.1 , pp. 20-27
    • Ii, M.1    Yamamoto, H.2    Adachi, Y.3    Maruyama, Y.4    Shinomura, Y.5
  • 29
    • 0034986503 scopus 로고    scopus 로고
    • Up-regulation of TRPM-2, MMP-7 and ID-1 during sex hormone-induced prostate carcinogenesis in the Noble rat
    • Ouyang XS, Wang X, Lee DT, Tsao SW, Wong YC. Up-regulation of TRPM-2, MMP-7 and ID-1 during sex hormone-induced prostate carcinogenesis in the Noble rat. Carcinogenesis 2001; 22(6):965-973.
    • (2001) Carcinogenesis , vol.22 , Issue.6 , pp. 965-973
    • Ouyang, X.S.1    Wang, X.2    Lee, D.T.3    Tsao, S.W.4    Wong, Y.C.5
  • 30
    • 33745714787 scopus 로고    scopus 로고
    • Role of the Survivin gene in pathophysiology
    • Li F, Brattain MG. Role of the Survivin gene in pathophysiology. Am J Pathol 2006;169(1):1-11.
    • (2006) Am J Pathol , vol.169 , Issue.1 , pp. 1-11
    • Li, F.1    Brattain, M.G.2
  • 31
    • 0024205612 scopus 로고
    • The human androgen receptor: Complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate
    • Lubahn DB, Joseph DR, Sar M, Tan J, Higgs HN, Larson RE, French FS, Wilson EM. The human androgen receptor: Complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate. Mol Endocrinol 1988;2(12):1265-1275.
    • (1988) Mol Endocrinol , vol.2 , Issue.12 , pp. 1265-1275
    • Lubahn, D.B.1    Joseph, D.R.2    Sar, M.3    Tan, J.4    Higgs, H.N.5    Larson, R.E.6    French, F.S.7    Wilson, E.M.8
  • 32
    • 0036755404 scopus 로고    scopus 로고
    • Androgen receptor as a target in androgen-independent prostate cancer
    • discussion 138-139
    • Balk SP. Androgen receptor as a target in androgen-independent prostate cancer. Urology 2002;60(3 Suppl 1):132-138; discussion 138-139.
    • (2002) Urology , vol.60 , Issue.3 SUPPL. 1 , pp. 132-138
    • Balk, S.P.1
  • 33
    • 33846603663 scopus 로고    scopus 로고
    • Androgen receptor coregulators and their involvement in the development and progression of prostate cancer
    • Chmelar R, Buchanan G, Need EF, Tilley W, Greenberg NM. Androgen receptor coregulators and their involvement in the development and progression of prostate cancer. Int J Cancer 2007;120(4):719-733.
    • (2007) Int J Cancer , vol.120 , Issue.4 , pp. 719-733
    • Chmelar, R.1    Buchanan, G.2    Need, E.F.3    Tilley, W.4    Greenberg, N.M.5
  • 36
    • 33645056171 scopus 로고    scopus 로고
    • Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
    • Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, Febbo PG, Balk SP. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006;66(5):2815-2825.
    • (2006) Cancer Res , vol.66 , Issue.5 , pp. 2815-2825
    • Stanbrough, M.1    Bubley, G.J.2    Ross, K.3    Golub, T.R.4    Rubin, M.A.5    Penning, T.M.6    Febbo, P.G.7    Balk, S.P.8
  • 37
    • 0141676080 scopus 로고    scopus 로고
    • Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: Implications for finasteride therapy of prostate carcinoma
    • Luo J, Dunn TA, Ewing CM, Walsh PC, Isaacs WB. Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: Implications for finasteride therapy of prostate carcinoma. Prostate 2003;57(2):134-139.
    • (2003) Prostate , vol.57 , Issue.2 , pp. 134-139
    • Luo, J.1    Dunn, T.A.2    Ewing, C.M.3    Walsh, P.C.4    Isaacs, W.B.5
  • 38
    • 17644362707 scopus 로고    scopus 로고
    • Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer
    • Thomas LN, Lazier CB, Gupta R, Norman RW, Troyer DA, O'Brien SP, Rittmaster RS. Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer. Prostate 2005;63(3):231-239.
    • (2005) Prostate , vol.63 , Issue.3 , pp. 231-239
    • Thomas, L.N.1    Lazier, C.B.2    Gupta, R.3    Norman, R.W.4    Troyer, D.A.5    O'Brien, S.P.6    Rittmaster, R.S.7
  • 40
    • 33745822086 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostate cancer
    • Shariff AH, Ather MH. Neuroendocrine differentiation in prostate cancer. Urology 2006;68(1):2-8.
    • (2006) Urology , vol.68 , Issue.1 , pp. 2-8
    • Shariff, A.H.1    Ather, M.H.2
  • 41
    • 0024440505 scopus 로고
    • The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an "endocrine marker
    • Abrahamsson PA, Falkmer S, Falt K, Grimelius L. The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an "endocrine marker". Pathol Res Pract 1989;185(3):373-380.
    • (1989) Pathol Res Pract , vol.185 , Issue.3 , pp. 373-380
    • Abrahamsson, P.A.1    Falkmer, S.2    Falt, K.3    Grimelius, L.4
  • 42
    • 1842788109 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy
    • discussion 592
    • Hirano D, Okada Y, Minei S, Takimoto Y, Nemoto N. Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy. Eur Urol 2004;45(5): 586-592; discussion 592.
    • (2004) Eur Urol , vol.45 , Issue.5 , pp. 586-592
    • Hirano, D.1    Okada, Y.2    Minei, S.3    Takimoto, Y.4    Nemoto, N.5
  • 43
    • 0033303702 scopus 로고    scopus 로고
    • Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells
    • Lu S, Tsai SY, Tsai MJ. Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells. Endocrinology 1999;140(11):5054-5059.
    • (1999) Endocrinology , vol.140 , Issue.11 , pp. 5054-5059
    • Lu, S.1    Tsai, S.Y.2    Tsai, M.J.3
  • 44
    • 0034749615 scopus 로고    scopus 로고
    • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
    • Murillo H, Huang H, Schmidt LJ, Smith DI, Tindall DJ. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 2001; 142(11):4795-4805.
    • (2001) Endocrinology , vol.142 , Issue.11 , pp. 4795-4805
    • Murillo, H.1    Huang, H.2    Schmidt, L.J.3    Smith, D.I.4    Tindall, D.J.5
  • 45
    • 0041833727 scopus 로고    scopus 로고
    • Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells
    • Wright ME, Tsai MJ, Aebersold R. Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol 2003;17(9):1726-1737.
    • (2003) Mol Endocrinol , vol.17 , Issue.9 , pp. 1726-1737
    • Wright, M.E.1    Tsai, M.J.2    Aebersold, R.3
  • 47
    • 0028290656 scopus 로고
    • Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer
    • Sehgal I, Powers S, Huntley B, Powis G, Pittelkow M, Maihle NJ. Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer. Proc Natl Acad Sci USA 1994;91(11):4673-4677.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.11 , pp. 4673-4677
    • Sehgal, I.1    Powers, S.2    Huntley, B.3    Powis, G.4    Pittelkow, M.5    Maihle, N.J.6
  • 49
    • 33845290622 scopus 로고    scopus 로고
    • Comprehensive expression analysis of L-dopa decarboxylase and established neuroendocrine markers in neoadjuvant hormone-treated versus varying Gleason grade prostate tumors
    • Wafa LA, Palmer J, Fazli L, Hurtado-Coll A, Bell RH, Nelson CC, Gleave ME, Cox ME, Rennie PS. Comprehensive expression analysis of L-dopa decarboxylase and established neuroendocrine markers in neoadjuvant hormone-treated versus varying Gleason grade prostate tumors. Hum Pathol 2007; 38(1):161-170.
    • (2007) Hum Pathol , vol.38 , Issue.1 , pp. 161-170
    • Wafa, L.A.1    Palmer, J.2    Fazli, L.3    Hurtado-Coll, A.4    Bell, R.H.5    Nelson, C.C.6    Gleave, M.E.7    Cox, M.E.8    Rennie, P.S.9
  • 50
    • 0024797778 scopus 로고
    • Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration
    • English HF, Kyprianou N, Isaacs JT. Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration. Prostate 1989;15(3):233-250.
    • (1989) Prostate , vol.15 , Issue.3 , pp. 233-250
    • English, H.F.1    Kyprianou, N.2    Isaacs, J.T.3
  • 52
    • 34248584876 scopus 로고    scopus 로고
    • In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer
    • Banerjee S, Hussain M, Wang Z, Saliganan A, Che M, Bonfil D, Cher M, Sarkar FH. In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Cancer Res 2007;67(8):3818-3826.
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3818-3826
    • Banerjee, S.1    Hussain, M.2    Wang, Z.3    Saliganan, A.4    Che, M.5    Bonfil, D.6    Cher, M.7    Sarkar, F.H.8
  • 53
    • 0019841416 scopus 로고
    • Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma
    • Isaacs JT, Coffey DS. Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma. Cancer Res 1981;41(12 Pt 1):5070-5075.
    • (1981) Cancer Res , vol.41 , Issue.12 PART 1 , pp. 5070-5075
    • Isaacs, J.T.1    Coffey, D.S.2
  • 54
    • 0033794201 scopus 로고    scopus 로고
    • Androgen deprivation induces selective outgrowth of aggressive hormone-refractory prostate cancer clones expressing distinct cellular and molecular properties not present in parental androgen-dependent cancer cells. [See comment]
    • Tso CL, McBride WH, Sun J, Patel B, Tsui KH, Paik SH, Gitlitz B, Caliliw R, van Ophoven A, Wu L, deKernion J, Belldegrun A. Androgen deprivation induces selective outgrowth of aggressive hormone-refractory prostate cancer clones expressing distinct cellular and molecular properties not present in parental androgen-dependent cancer cells. [See comment]. Cancer J 2000; 6(4):220-233.
    • (2000) Cancer J , vol.6 , Issue.4 , pp. 220-233
    • Tso, C.L.1    McBride, W.H.2    Sun, J.3    Patel, B.4    Tsui, K.H.5    Paik, S.H.6    Gitlitz, B.7    Caliliw, R.8    van Ophoven, A.9    Wu, L.10    deKernion, J.11    Belldegrun, A.12
  • 55
    • 15844429706 scopus 로고    scopus 로고
    • Mechanisms of the development of androgen independence in prostate cancer
    • So A, Gleave M, Hurtado-Col A, Nelson C. Mechanisms of the development of androgen independence in prostate cancer. World J Urol 2005;23(1):1-9.
    • (2005) World J Urol , vol.23 , Issue.1 , pp. 1-9
    • So, A.1    Gleave, M.2    Hurtado-Col, A.3    Nelson, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.