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Volumn 11, Issue 12, 2005, Pages 4365-4371

Steroid 5α-reductase isozymes I and II in recurrent prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; ISOENZYME; POLYCLONAL ANTIBODY; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE I; STEROID 5ALPHA REDUCTASE II; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 20444476601     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-0738     Document Type: Article
Times cited : (158)

References (50)
  • 2
    • 0036680098 scopus 로고    scopus 로고
    • Hormones and prostate cancer: Current perspectives and future directions
    • Hsing AW, Reichardt JKV, Stanczyk FZ. Hormones and prostate cancer: current perspectives and future directions. Prostate 2002;52:213-35.
    • (2002) Prostate , vol.52 , pp. 213-235
    • Hsing, A.W.1    Reichardt, J.K.V.2    Stanczyk, F.Z.3
  • 3
    • 0024318399 scopus 로고
    • Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat, guinea pig after castration: Unique importance of extratesticular androgens in men
    • Balanger B, Balanger A, Labrie F, Dupont A, Cusan L, Monfette G. Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat, guinea pig after castration: unique importance of extratesticular androgens in men. J Steroid Biochem 1989;32:695-8.
    • (1989) J Steroid Biochem , vol.32 , pp. 695-698
    • Balanger, B.1    Balanger, A.2    Labrie, F.3    Dupont, A.4    Cusan, L.5    Monfette, G.6
  • 4
    • 0028173882 scopus 로고
    • Steroid 5α-reductase: Two genes two enzymes
    • Russell DW, Wilson JD. Steroid 5α-reductase: two genes two enzymes. Annu Rev Biochem 1994;63:25-61.
    • (1994) Annu Rev Biochem , vol.63 , pp. 25-61
    • Russell, D.W.1    Wilson, J.D.2
  • 6
    • 0029873670 scopus 로고    scopus 로고
    • Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer
    • Denmeade SR, Lin XS, Isaacs JT. Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. Prostate 1996;28:251-65.
    • (1996) Prostate , vol.28 , pp. 251-265
    • Denmeade, S.R.1    Lin, X.S.2    Isaacs, J.T.3
  • 7
    • 0001189211 scopus 로고
    • Studies on prostatic cancer: 2. The effects of castration on advanced carcinoma of the prostate gland
    • Huggins CB, Stephens RC, Hodges CV. Studies on prostatic cancer: 2. The effects of castration on advanced carcinoma of the prostate gland. Arch Surg 1941;43:209-12.
    • (1941) Arch Surg , vol.43 , pp. 209-212
    • Huggins, C.B.1    Stephens, R.C.2    Hodges, C.V.3
  • 8
    • 0031038011 scopus 로고    scopus 로고
    • Human androgen receptor expression in prostate cancer following androgen ablation
    • De Vere White R, Meyers F, Chi SG, et al. Human androgen receptor expression in prostate cancer following androgen ablation. Eur Urol 1997;31:1-6.
    • (1997) Eur Urol , vol.31 , pp. 1-6
    • De Vere White, R.1    Meyers, F.2    Chi, S.G.3
  • 9
    • 0031946389 scopus 로고    scopus 로고
    • Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
    • Culig Z, Hobisch A, Hittmair A, et al. Expression, structure, and function of androgen receptor in advanced prostatic carcinoma. Prostate 1998;35:63-70.
    • (1998) Prostate , vol.35 , pp. 63-70
    • Culig, Z.1    Hobisch, A.2    Hittmair, A.3
  • 10
    • 0842311632 scopus 로고    scopus 로고
    • The androgen axis in recurrent prostate cancer
    • Mohler JL, Gregory CW, Ford OH, et al. The androgen axis in recurrent prostate cancer. Clin Cancer Res 2004;10:440-8.
    • (2004) Clin Cancer Res , vol.10 , pp. 440-448
    • Mohler, J.L.1    Gregory, C.W.2    Ford, O.H.3
  • 11
    • 0032535307 scopus 로고    scopus 로고
    • Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
    • Gregory CW, Hamil KG, Kim D, et al. Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 1998;58:5718-24.
    • (1998) Cancer Res , vol.58 , pp. 5718-5724
    • Gregory, C.W.1    Hamil, K.G.2    Kim, D.3
  • 12
    • 0035845850 scopus 로고    scopus 로고
    • Failure of hormone therapy in prostate cancer involves systemic restoration of androgen responsive genes and activation of rapamycin sensitive signaling
    • Mousses S, Wagner U, Chen Y, et al. Failure of hormone therapy in prostate cancer involves systemic restoration of androgen responsive genes and activation of rapamycin sensitive signaling. Oncogene 2001;20:6718-23.
    • (2001) Oncogene , vol.20 , pp. 6718-6723
    • Mousses, S.1    Wagner, U.2    Chen, Y.3
  • 13
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene in progression of human prostate cancer
    • Visakorpi T, Hytinen E, Koivist P, et al. In vivo amplification of the androgen receptor gene in progression of human prostate cancer. Nat Genet 1995;9:401-6.
    • (1995) Nat Genet , vol.9 , pp. 401-406
    • Visakorpi, T.1    Hytinen, E.2    Koivist, P.3
  • 14
    • 0034566055 scopus 로고    scopus 로고
    • Expression and function of androgen receptor in carcinoma of the prostate
    • Culig Z, Hobisch A, Bartsch G, Klocker H. Expression and function of androgen receptor in carcinoma of the prostate. Microsc Res Tech 2000;51:447-55.
    • (2000) Microsc Res Tech , vol.51 , pp. 447-455
    • Culig, Z.1    Hobisch, A.2    Bartsch, G.3    Klocker, H.4
  • 15
    • 8244262043 scopus 로고    scopus 로고
    • Dehydroepiandrosterone activates mutant androgen receptor expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells
    • Tan J-A, Sharief Y, Hamil KG, et al. Dehydroepiandrosterone activates mutant androgen receptor expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells. Mol Endocrinol 1997;11:450-9.
    • (1997) Mol Endocrinol , vol.11 , pp. 450-459
    • Tan, J.-A.1    Sharief, Y.2    Hamil, K.G.3
  • 16
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 17
    • 0036219874 scopus 로고    scopus 로고
    • Mechanisms involved in the progression of androgen-independent prostate cancers: It is not only the cancer cell's fault
    • Arnold JT, Isaacs JT. Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault. Endocr Relat Cancer 2002;9:61-73.
    • (2002) Endocr Relat Cancer , vol.9 , pp. 61-73
    • Arnold, J.T.1    Isaacs, J.T.2
  • 18
    • 0037812658 scopus 로고    scopus 로고
    • The influence of finasteride on the development of prostate cancer
    • Thompson IM, Goodman PJ, Tangen CM, et al. The influence of finasteride on the development of prostate cancer. N Engl J Med 2003;349:215-24.
    • (2003) N Engl J Med , vol.349 , pp. 215-224
    • Thompson, I.M.1    Goodman, P.J.2    Tangen, C.M.3
  • 19
    • 0035361340 scopus 로고    scopus 로고
    • A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
    • Gregory CW, He B, Johnson RT, et al. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 2001;61:4315-9.
    • (2001) Cancer Res , vol.61 , pp. 4315-4319
    • Gregory, C.W.1    He, B.2    Johnson, R.T.3
  • 20
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 1998;4:844-7.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 21
    • 0032940563 scopus 로고    scopus 로고
    • Immunohistochemical quantitation of androgen receptor expression using color video image analysis
    • Kim D, Gregory CW, Smith GJ, Mohler JL. Immunohistochemical quantitation of androgen receptor expression using color video image analysis. Cytometry 1999;35:2-10.
    • (1999) Cytometry , vol.35 , pp. 2-10
    • Kim, D.1    Gregory, C.W.2    Smith, G.J.3    Mohler, J.L.4
  • 22
    • 0141988845 scopus 로고    scopus 로고
    • 5α-reductase type 1 immunostaining is enhanced in some prostate cancers compared with benign prostatic hyperplasia epithelium
    • Thomas LN, Douglas RC, Vessey JP, et al. 5α-reductase type 1 immunostaining is enhanced in some prostate cancers compared with benign prostatic hyperplasia epithelium. J Urol 2003;170:2019-25.
    • (2003) J Urol , vol.170 , pp. 2019-2025
    • Thomas, L.N.1    Douglas, R.C.2    Vessey, J.P.3
  • 23
    • 0026643758 scopus 로고
    • The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia
    • Shapiro E, Becich MJ, Hartanto V, Lepor H. The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia. J Urol 1992;147:1293-7.
    • (1992) J Urol , vol.147 , pp. 1293-1297
    • Shapiro, E.1    Becich, M.J.2    Hartanto, V.3    Lepor, H.4
  • 24
    • 0027166764 scopus 로고
    • Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue
    • Miyamoto KK, McSherry SA, Dent GA, et al. Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue. J Urol 1993;149:1015-9.
    • (1993) J Urol , vol.149 , pp. 1015-1019
    • Miyamoto, K.K.1    McSherry, S.A.2    Dent, G.A.3
  • 25
    • 0016458753 scopus 로고
    • Reduced nicotinamide adenine dinucleotide phosphate: δ-4-3- ketosteroid 5α-oxidoreductase
    • Moore RJ, Wilson JD. Reduced nicotinamide adenine dinucleotide phosphate: δ-4-3-ketosteroid 5α-oxidoreductase. Methods Enzymol 1975;36:466-74.
    • (1975) Methods Enzymol , vol.36 , pp. 466-474
    • Moore, R.J.1    Wilson, J.D.2
  • 27
    • 0034744568 scopus 로고    scopus 로고
    • Characterization of the 5α-reductase-3-hydroxysteroid dehydrogenase complex in the human brain
    • Steckelbroeck S, Watzka M, Reichelt R, et al. Characterization of the 5α-reductase-3-hydroxysteroid dehydrogenase complex in the human brain. J Clin Endocrinol Metab 2001;86:1324-31.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1324-1331
    • Steckelbroeck, S.1    Watzka, M.2    Reichelt, R.3
  • 28
    • 0031018808 scopus 로고    scopus 로고
    • Immunocytochemical evidence for differential subcellular localization of 5α-reductase isoenzymes in human tissues
    • Aumuller G, Eicheler W, Renneberg H, Adermann K, Vilja P, Forssman WG. Immunocytochemical evidence for differential subcellular localization of 5α-reductase isoenzymes in human tissues. Acta Anat (Basel) 1996;156:241-52.
    • (1996) Acta Anat (Basel) , vol.156 , pp. 241-252
    • Aumuller, G.1    Eicheler, W.2    Renneberg, H.3    Adermann, K.4    Vilja, P.5    Forssman, W.G.6
  • 29
    • 0029910571 scopus 로고    scopus 로고
    • Differential expression of 5α-reductase isoenzymes in human prostate and prostatic carcinomas
    • Bonkhoff H, Stein U, Aumuller G, Remberger K. Differential expression of 5α-reductase isoenzymes in human prostate and prostatic carcinomas. Prostate 1996;29:261-7.
    • (1996) Prostate , vol.29 , pp. 261-267
    • Bonkhoff, H.1    Stein, U.2    Aumuller, G.3    Remberger, K.4
  • 30
    • 0021914207 scopus 로고
    • Discrimination between normal, hyperplastic and malignant human prostatic tissues by enzymatic profiles
    • Brendler CB, Follansbee AL, Isaacs JT. Discrimination between normal, hyperplastic and malignant human prostatic tissues by enzymatic profiles. J Urol 1985;133:495-501.
    • (1985) J Urol , vol.133 , pp. 495-501
    • Brendler, C.B.1    Follansbee, A.L.2    Isaacs, J.T.3
  • 31
    • 0347986651 scopus 로고    scopus 로고
    • Messenger RNA levels and enzyme activities of 5α-reductase types 1 and 2 in human benign prostatic hyperplasia (BPH) tissue
    • Shirakawa T, Okada H, Acharya B, et al. Messenger RNA levels and enzyme activities of 5α-reductase types 1 and 2 in human benign prostatic hyperplasia (BPH) tissue. Prostate 2004;58:33-40.
    • (2004) Prostate , vol.58 , pp. 33-40
    • Shirakawa, T.1    Okada, H.2    Acharya, B.3
  • 32
    • 0035094483 scopus 로고    scopus 로고
    • Messenger ribonucleic acid levels of steroid 5α-reductase 2 in human prostate predict the enzyme activity
    • Soderstrom TG, Bjelfman C, Brekkan E, et al. Messenger ribonucleic acid levels of steroid 5α-reductase 2 in human prostate predict the enzyme activity. J Clin Endocrinol Metab 2001;86:855-8.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 855-858
    • Soderstrom, T.G.1    Bjelfman, C.2    Brekkan, E.3
  • 33
    • 0034351821 scopus 로고    scopus 로고
    • Enzyme assay for 5α-reductase type 2 activity in the presence of 5α-reductase type I activity in rat testis
    • Pratis K, O'Donnell L, Ooi GT, McLachian RI, Robertson DM, Enzyme assay for 5α-reductase type 2 activity in the presence of 5α-reductase type I activity in rat testis. J Steroid Biochem Mol Biol 2000;75:75-82.
    • (2000) J Steroid Biochem Mol Biol , vol.75 , pp. 75-82
    • Pratis, K.1    O'Donnell, L.2    Ooi, G.T.3    McLachian, R.I.4    Robertson, D.M.5
  • 34
    • 17444446412 scopus 로고    scopus 로고
    • Endothelial cell proliferation activity in benign prostatic hyperplasia and prostate cancer: An in vitro model for assessment
    • Weingartner K, Ben-Sasson SA, Stewart R, Richie JP, Riedmiller H, Folkman J. Endothelial cell proliferation activity in benign prostatic hyperplasia and prostate cancer: an in vitro model for assessment. J Urol 1998;159:465-70.
    • (1998) J Urol , vol.159 , pp. 465-470
    • Weingartner, K.1    Ben-Sasson, S.A.2    Stewart, R.3    Richie, J.P.4    Riedmiller, H.5    Folkman, J.6
  • 35
    • 0029614856 scopus 로고
    • Microvascularization invasion of prostate cancer correlates with pathologic stage
    • Salomao DR, Graham SD, Bostwick DB. Microvascularization invasion of prostate cancer correlates with pathologic stage. Arch Pathol Lab Med 1995;119:1050-4.
    • (1995) Arch Pathol Lab Med , vol.119 , pp. 1050-1054
    • Salomao, D.R.1    Graham, S.D.2    Bostwick, D.B.3
  • 36
    • 0038004462 scopus 로고    scopus 로고
    • Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate cancer cells
    • Mabjeesh NJ, Willard MT, Frederickson CE, Simons JW. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3′-kinase/protein kinase B in prostate cancer cells. Clin Cancer Res 2003;9:2416-25.
    • (2003) Clin Cancer Res , vol.9 , pp. 2416-2425
    • Mabjeesh, N.J.1    Willard, M.T.2    Frederickson, C.E.3    Simons, J.W.4
  • 37
    • 0033571682 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases
    • Zhong H, De Marzo AM, Laughner E, et al. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 1999;59:5830-5.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.M.2    Laughner, E.3
  • 38
    • 0034671307 scopus 로고    scopus 로고
    • Hypoxia-inducible expression of tumor-associated carbonic anhydrases
    • Wykoff CC, Beasley NJP, Watson PH, et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000;60:7075-83.
    • (2000) Cancer Res , vol.60 , pp. 7075-7083
    • Wykoff, C.C.1    Beasley, N.J.P.2    Watson, P.H.3
  • 39
    • 0842288274 scopus 로고    scopus 로고
    • High cell density induces expression from the carbonic anhydrase 9 promoter
    • Kaluzova M, Kaluz S, Stanbridge EJ. High cell density induces expression from the carbonic anhydrase 9 promoter. Biotechniques 2004;36:228-34.
    • (2004) Biotechniques , vol.36 , pp. 228-234
    • Kaluzova, M.1    Kaluz, S.2    Stanbridge, E.J.3
  • 41
    • 0034743536 scopus 로고    scopus 로고
    • Steroid 5-reductases and 3-hydroxysteroid dehydrogenases: Key enzymes in androgen metabolism
    • Jin Y, Penning TM. Steroid 5-reductases and 3-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism. Best Pract Res Clin Endocrinol Metab 2001;15:79-94.
    • (2001) Best Pract Res Clin Endocrinol Metab , vol.15 , pp. 79-94
    • Jin, Y.1    Penning, T.M.2
  • 44
    • 9144254440 scopus 로고    scopus 로고
    • Phase I and clinical pharmacology of a type I and II, 5-α-reductase inhibitor (LY320236) in prostate cancer: Elevation of estradiol as possible mechanism of action
    • Eisenberger MA, Laufer M, Vogelzang NJ, et al. Phase I and clinical pharmacology of a type I and II, 5-α-reductase inhibitor (LY320236) in prostate cancer: elevation of estradiol as possible mechanism of action. Urology 2004;63:114-9.
    • (2004) Urology , vol.63 , pp. 114-119
    • Eisenberger, M.A.1    Laufer, M.2    Vogelzang, N.J.3
  • 45
    • 0037105670 scopus 로고    scopus 로고
    • Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines
    • Kim IY, Kim B-C, Seong DH, et al. Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines. Cancer Res 2002;62:5365-9.
    • (2002) Cancer Res , vol.62 , pp. 5365-5369
    • Kim, I.Y.1    Kim, B.-C.2    Seong, D.H.3
  • 46
    • 0032145396 scopus 로고    scopus 로고
    • A phase II trial of oral diethylstielbesterol as a second-line hormonal agent in advanced prostate cancer
    • Smith DC, Redman BG, Flaherty LE, Li L, Strawderman WI, Pienta KJ. A phase II trial of oral diethylstielbesterol as a second-line hormonal agent in advanced prostate cancer. Urology 1998;52:257-60.
    • (1998) Urology , vol.52 , pp. 257-260
    • Smith, D.C.1    Redman, B.G.2    Flaherty, L.E.3    Li, L.4    Strawderman, W.I.5    Pienta, K.J.6
  • 47
    • 0025373464 scopus 로고
    • Genotoxic effects of estrogens
    • Liehr JG. Genotoxic effects of estrogens. Mutat Res 1990;238:269-76.
    • (1990) Mutat Res , vol.238 , pp. 269-276
    • Liehr, J.G.1
  • 49
    • 0028799960 scopus 로고
    • Combination finasteride and flutamide in advanced carcinoma of the prostate: Effective therapy with minimal side effects
    • Fleshner NE, Trachtenberg J. Combination finasteride and flutamide in advanced carcinoma of the prostate: effective therapy with minimal side effects. J Urol 1995;154:1642-6.
    • (1995) J Urol , vol.154 , pp. 1642-1646
    • Fleshner, N.E.1    Trachtenberg, J.2
  • 50
    • 0036754256 scopus 로고    scopus 로고
    • Efficacy and safety of a dual inhibitor of 5-α-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia
    • Roehrborn CG, Boyle J, Nickel JC, Hoefner K, Andriole G. Efficacy and safety of a dual inhibitor of 5-α-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia. Urology 2002;60:434-41.
    • (2002) Urology , vol.60 , pp. 434-441
    • Roehrborn, C.G.1    Boyle, J.2    Nickel, J.C.3    Hoefner, K.4    Andriole, G.5


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