-
1
-
-
0032568370
-
E-cadherin germline mutations in familial gastric cancer
-
Guilford P, Hopkins J, Harraway J et al.: E-cadherin germline mutations in familial gastric cancer. Nature 392, 402-405 (1998).
-
(1998)
Nature
, vol.392
, pp. 402-405
-
-
Guilford, P.1
Hopkins, J.2
Harraway, J.3
-
2
-
-
0037459077
-
Sticky business: Orchestrating cellular signals at adherens junctions
-
Perez-Moreno M, Jamora C, Fuchs E: Sticky business: orchestrating cellular signals at adherens junctions. Cell 112, 535-548 (2003).
-
(2003)
Cell
, vol.112
, pp. 535-548
-
-
Perez-Moreno, M.1
Jamora, C.2
Fuchs, E.3
-
3
-
-
0035347391
-
Loss of E-cadherin is the fundamental defect in diffuse-type gastric carcinoma and infiltrating lobular carcinoma of the breast
-
Chan JK, Wong CS: Loss of E-cadherin is the fundamental defect in diffuse-type gastric carcinoma and infiltrating lobular carcinoma of the breast. Adv. Anat. Pathol. 8, 165-172 (2001).
-
(2001)
Adv. Anat. Pathol
, vol.8
, pp. 165-172
-
-
Chan, J.K.1
Wong, C.S.2
-
4
-
-
2442698759
-
Hereditary diffuse gastric cancer: Predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone
-
Charlton A, Blair V, Shaw D, Parry S, Guilford P, Martin IG: Hereditary diffuse gastric cancer: predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone. Cut 53, 814-820 (2004).
-
(2004)
Cut
, vol.53
, pp. 814-820
-
-
Charlton, A.1
Blair, V.2
Shaw, D.3
Parry, S.4
Guilford, P.5
Martin, I.G.6
-
5
-
-
0035927967
-
Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations
-
Huntsman DG, Carneiro F, Lewis FR et al.: Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations. N. Engl. J. Med. 344, 1904-1909 (2001).
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 1904-1909
-
-
Huntsman, D.G.1
Carneiro, F.2
Lewis, F.R.3
-
6
-
-
0035395151
-
Germline E-cadherin gene mutations: Is prophylactic total gastrectomy indicated?
-
Chun YS, Lindor NM, Smyrk TC et al.: Germline E-cadherin gene mutations: is prophylactic total gastrectomy indicated? Cancer 92, 181-187 (2001).
-
(2001)
Cancer
, vol.92
, pp. 181-187
-
-
Chun, Y.S.1
Lindor, N.M.2
Smyrk, T.C.3
-
7
-
-
34047248572
-
Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer
-
Humar B, Fukuzawa R, Blair V et al.: Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res. 67, 2480-2489 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 2480-2489
-
-
Humar, B.1
Fukuzawa, R.2
Blair, V.3
-
8
-
-
0037686144
-
Defining epithelial cell progenitors in the human oxyntic mucosa
-
Karam SM, Straiton T, Hassan WM, Leblond CP: Defining epithelial cell progenitors in the human oxyntic mucosa. Stem Cells 21, 322-336 (2003).
-
(2003)
Stem Cells
, vol.21
, pp. 322-336
-
-
Karam, S.M.1
Straiton, T.2
Hassan, W.M.3
Leblond, C.P.4
-
9
-
-
2642556280
-
Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening
-
Carneiro F, Huntsman DG, Smyrk TC et al.: Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. J. Pathol. 203, 681-687 (2004).
-
(2004)
J. Pathol
, vol.203
, pp. 681-687
-
-
Carneiro, F.1
Huntsman, D.G.2
Smyrk, T.C.3
-
10
-
-
0033816924
-
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
-
Grady WM, Willis J, Guilford PJ et al.: Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer. Nat. Genet. 26, 16-17 (2000).
-
(2000)
Nat. Genet
, vol.26
, pp. 16-17
-
-
Grady, W.M.1
Willis, J.2
Guilford, P.J.3
-
11
-
-
35549011087
-
Characterization of the P373L E-cadherin germline missense mutation and implication for clinical management
-
Corso G, Roviello F, Paredes J et al.: Characterization of the P373L E-cadherin germline missense mutation and implication for clinical management. Eur. J. Surg. Oncol. 33, 1061-1067 (2007).
-
(2007)
Eur. J. Surg. Oncol
, vol.33
, pp. 1061-1067
-
-
Corso, G.1
Roviello, F.2
Paredes, J.3
-
12
-
-
34047190317
-
Epigenetic field for cancerization
-
Ushijima T: Epigenetic field for cancerization. J. Biochem. Mol. Biol. 40, 142-150 (2007).
-
(2007)
J. Biochem. Mol. Biol
, vol.40
, pp. 142-150
-
-
Ushijima, T.1
-
14
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/ HDAC2 complex
-
Peinado H, Ballestar E, Esteller M, Cano A: Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/ HDAC2 complex. Mol. Cell. Biol. 24, 306-319 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
15
-
-
1842591223
-
Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour
-
Oliveira C, de Bruin J, Nabais S et al.: Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. Oncogene 23, 2236-2240 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 2236-2240
-
-
Oliveira, C.1
de Bruin, J.2
Nabais, S.3
-
16
-
-
0034116268
-
Selective degradation of E-cadherin and dissolution of E-cadherin -catenin complexes in epithelial ischemia
-
Bush KT, Tsukamoto T, Nigam SK: Selective degradation of E-cadherin and dissolution of E-cadherin -catenin complexes in epithelial ischemia. Am. J. Physiol. Renal Physiol. 278, F847-F852 (2000).
-
(2000)
Am. J. Physiol. Renal Physiol
, vol.278
-
-
Bush, K.T.1
Tsukamoto, T.2
Nigam, S.K.3
-
18
-
-
0037154004
-
Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage
-
le Borgne R, Bellaiche Y, Schweisguth F: Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage. Curr. Biol. 12, 95-104 (2002).
-
(2002)
Curr. Biol
, vol.12
, pp. 95-104
-
-
le Borgne, R.1
Bellaiche, Y.2
Schweisguth, F.3
-
19
-
-
3242667728
-
Lineage allocation and cell polarity during mouse embryogenesis
-
Johnson MH, McConnell IM: Lineage allocation and cell polarity during mouse embryogenesis. Semin. Cell Dev. Biol. 15, 583-597 (2004).
-
(2004)
Semin. Cell Dev. Biol
, vol.15
, pp. 583-597
-
-
Johnson, M.H.1
McConnell, I.M.2
-
20
-
-
0025818032
-
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
-
Vleminckx K, Vakaet L, Mareel M, Fiers W, van Roy F: Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66, 107-119 (1991).
-
(1991)
Cell
, vol.66
, pp. 107-119
-
-
Vleminckx, K.1
Vakaet, L.2
Mareel, M.3
Fiers, W.4
van Roy, F.5
-
21
-
-
0037068393
-
DNA methylation and gene silencing in cancer: Which is the guilty party?
-
Clark SJ, Melki J: DNA methylation and gene silencing in cancer: which is the guilty party? Oncogene 21, 5380-5387 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 5380-5387
-
-
Clark, S.J.1
Melki, J.2
-
22
-
-
34547765951
-
Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis
-
Clark SJ: Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis. Hum. Mol. Genet. 16(Spec. No. 1), R88-R95 (2007).
-
(2007)
Hum. Mol. Genet
, vol.16
, Issue.SPEC. 1
-
-
Clark, S.J.1
-
23
-
-
0842307061
-
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9
-
Mutskov V, Felsenfeld G: Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J. 23, 138-149 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 138-149
-
-
Mutskov, V.1
Felsenfeld, G.2
-
24
-
-
0032534028
-
The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation
-
Mummaneni P, Yates P, Simpson J, Rose J, Turker MS: The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation. Nucleic Acids Res. 26, 5163-5169 (1998).
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 5163-5169
-
-
Mummaneni, P.1
Yates, P.2
Simpson, J.3
Rose, J.4
Turker, M.S.5
-
25
-
-
9144222659
-
Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible
-
Tagoh H, Schebesta A, Lefevre P et al.: Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible, EMBO J. 23, 4275-4285 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4275-4285
-
-
Tagoh, H.1
Schebesta, A.2
Lefevre, P.3
-
26
-
-
0141537154
-
Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasla, and chronic inflammation
-
Kang GH, Lee HJ, Hwang KS, Lee S, Kim JH, Kim JS: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasla, and chronic inflammation. Am. J. Pathol. 163, 1551-1556 (2003).
-
(2003)
Am. J. Pathol
, vol.163
, pp. 1551-1556
-
-
Kang, G.H.1
Lee, H.J.2
Hwang, K.S.3
Lee, S.4
Kim, J.H.5
Kim, J.S.6
-
27
-
-
0030091627
-
P14yford RJ, Pignatelli M: Downregulation of E-cadherin in the reparative epithelium of the human gastrointestinal tract
-
Hanby AM, Chinery R, Poulsom R, P14yford RJ, Pignatelli M: Downregulation of E-cadherin in the reparative epithelium of the human gastrointestinal tract. Am. J. Pathol. 148, 723-729 (1996).
-
(1996)
Am. J. Pathol
, vol.148
, pp. 723-729
-
-
Hanby, A.M.1
Chinery, R.2
Poulsom, R.3
-
28
-
-
0034514406
-
Focal up-regulation of E-cadherin-catenin complex in inflamed bowel mucosa but reduced expression in ulcer-associated cell lineage
-
Demetter P, de Vos M, van Damme N et al.: Focal up-regulation of E-cadherin-catenin complex in inflamed bowel mucosa but reduced expression in ulcer-associated cell lineage. Am. J. Clin. Pathol. 114, 364-370 (2000).
-
(2000)
Am. J. Clin. Pathol
, vol.114
, pp. 364-370
-
-
Demetter, P.1
de Vos, M.2
van Damme, N.3
-
29
-
-
0028959170
-
E-cadherin expression in intestinal epithelium
-
Dogan A, Wang ZD, Spencer J: E-cadherin expression in intestinal epithelium. J. Clin. Pathol. 48, 143-146 (1995).
-
(1995)
J. Clin. Pathol
, vol.48
, pp. 143-146
-
-
Dogan, A.1
Wang, Z.D.2
Spencer, J.3
-
30
-
-
0031809678
-
H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control
-
Terres AM, Pajares JM. O'Toole D, Ahern S, Kelleher D: H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control. J. Clin. Pathol. 51, 410-412 (1998).
-
(1998)
J. Clin. Pathol
, vol.51
, pp. 410-412
-
-
Terres, A.M.1
Pajares, J.M.2
O'Toole, D.3
Ahern, S.4
Kelleher, D.5
-
31
-
-
33645090169
-
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B
-
Krishnamachary B, Zagzag D, Nagasawa H et al.: Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res. 66, 2725-2731 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 2725-2731
-
-
Krishnamachary, B.1
Zagzag, D.2
Nagasawa, H.3
-
32
-
-
0141760411
-
Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
-
Imai T, Horiuchi A, Wang C et al.: Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am. J. Pathol. 163, 1437-1447 (2003).
-
(2003)
Am. J. Pathol
, vol.163
, pp. 1437-1447
-
-
Imai, T.1
Horiuchi, A.2
Wang, C.3
-
33
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW et al.: The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen dependent proteolysis. Nature 399, 271-275 (1999).
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
34
-
-
17044452288
-
HIF activation-identifies early lesions in VHL kidneys: Evidence for site-specific tumor suppressor function in the nephron
-
Mandriota SJ, Turner KJ, Davies DR et al.: HIF activation-identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell 1, 459-468 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 459-468
-
-
Mandriota, S.J.1
Turner, K.J.2
Davies, D.R.3
-
35
-
-
33645748171
-
Regulation of E-cadherin expression by VHL and hypoxia-inducible factor
-
Esteban MA, Tran MG. Harten SK et al.: Regulation of E-cadherin expression by VHL and hypoxia-inducible factor. Cancer Res. 66, 3567-3575 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 3567-3575
-
-
Esteban, M.A.1
Tran, M.G.2
Harten, S.K.3
-
36
-
-
33744925683
-
Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
-
Dohadwala M, Yang SC, Luo J et al.: Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 66, 5338-5345 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 5338-5345
-
-
Dohadwala, M.1
Yang, S.C.2
Luo, J.3
-
37
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado H, Olmeda D, Cano A: Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. 7, 415-428 (2007).
-
(2007)
Nat. Rev
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
38
-
-
0031802252
-
Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer
-
Huang JQ, Sridhar S, Chen Y, Hunt RH: Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology 114, 1169-1179 (1998).
-
(1998)
Gastroenterology
, vol.114
, pp. 1169-1179
-
-
Huang, J.Q.1
Sridhar, S.2
Chen, Y.3
Hunt, R.H.4
-
39
-
-
34547625912
-
The association between Helicobacter pylori infection and early gastric cancer: A meta-analysis
-
Wang C, Yuan Y, Hunt RH: The association between Helicobacter pylori infection and early gastric cancer: a meta-analysis. Am. J. Gastroenterol. 102, 1789-1798 (2007).
-
(2007)
Am. J. Gastroenterol
, vol.102
, pp. 1789-1798
-
-
Wang, C.1
Yuan, Y.2
Hunt, R.H.3
-
40
-
-
32944459562
-
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
-
Maekita T, Nakazawa K, Mihara M et al.: High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin. Cancer Res. 12, 989-995 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 989-995
-
-
Maekita, T.1
Nakazawa, K.2
Mihara, M.3
-
41
-
-
12244267687
-
Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1α in gastric cancer cells
-
Park JH, Kim TY, Jong HS et al.: Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1α in gastric cancer cells. Clin. Cancer Res. 9, 433-440 (2003).
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 433-440
-
-
Park, J.H.1
Kim, T.Y.2
Jong, H.S.3
-
42
-
-
0031011444
-
The epidermal stem cell compartment: Variation in expression levels of E-cadherin and catenins within the basal layer of human epidermis
-
Moles JP, Watt FM: The epidermal stem cell compartment: variation in expression levels of E-cadherin and catenins within the basal layer of human epidermis, J. Histochem. Cytochem. 45, 867-874 (1997).
-
(1997)
J. Histochem. Cytochem
, vol.45
, pp. 867-874
-
-
Moles, J.P.1
Watt, F.M.2
-
43
-
-
9244230606
-
Repressed E-cadherin expression in the lower crypt of human small intestine: A cell marker of functional relevance
-
Escaffit F, Perreault N, Jean D et al.: Repressed E-cadherin expression in the lower crypt of human small intestine: a cell marker of functional relevance. Exp. Cell Res. 302, 206-220 (2005).
-
(2005)
Exp. Cell Res
, vol.302
, pp. 206-220
-
-
Escaffit, F.1
Perreault, N.2
Jean, D.3
-
44
-
-
33846065117
-
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells
-
Capaldo CT, Macara IG: Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Mol. Biol. Cell 18, 189-200 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 189-200
-
-
Capaldo, C.T.1
Macara, I.G.2
-
45
-
-
0030045345
-
Origins of cell polarity
-
Drubin DG, Nelson WJ: Origins of cell polarity. Cell 84, 335-344 (1996).
-
(1996)
Cell
, vol.84
, pp. 335-344
-
-
Drubin, D.G.1
Nelson, W.J.2
-
46
-
-
34447513236
-
A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity
-
Nejsum LN, Nelson WJ: A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity. J. Cell Biol. 178, 323-335 (2007).
-
(2007)
J. Cell Biol
, vol.178
, pp. 323-335
-
-
Nejsum, L.N.1
Nelson, W.J.2
-
47
-
-
0023020417
-
Establishment of the mechanism of cytokinesis in animal cells
-
Rappaport R: Establishment of the mechanism of cytokinesis in animal cells. Int. Rev. Cytol. 105, 245-281 (1986).
-
(1986)
Int. Rev. Cytol
, vol.105
, pp. 245-281
-
-
Rappaport, R.1
-
48
-
-
24644494270
-
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
-
Lechler T, Fuchs E: Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 437, 275-280 (2005).
-
(2005)
Nature
, vol.437
, pp. 275-280
-
-
Lechler, T.1
Fuchs, E.2
-
49
-
-
0028101021
-
Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells
-
Reinsch S, Karsenti E: Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells. J Cell Biol. 126, 1509-1526 (1994).
-
(1994)
J Cell Biol
, vol.126
, pp. 1509-1526
-
-
Reinsch, S.1
Karsenti, E.2
-
50
-
-
0035945614
-
Adherens junctions inhibit asymmetric division in the Drosopbila epithelium
-
Lu B, Roegiers F, Jan LY, Jan YN: Adherens junctions inhibit asymmetric division in the Drosopbila epithelium. Nature 409, 522-525 (2001).
-
(2001)
Nature
, vol.409
, pp. 522-525
-
-
Lu, B.1
Roegiers, F.2
Jan, L.Y.3
Jan, Y.N.4
-
52
-
-
33645525794
-
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
-
Lee CY, Wilkinson BD, Siegrist SE, Wharton RP, Doe CQ: Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev. Cell 10, 441-449 (2006).
-
(2006)
Dev. Cell
, vol.10
, pp. 441-449
-
-
Lee, C.Y.1
Wilkinson, B.D.2
Siegrist, S.E.3
Wharton, R.P.4
Doe, C.Q.5
-
53
-
-
33646027006
-
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
-
Betschinger J, Mechtler K, Knoblich JA: Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253 (2006).
-
(2006)
Cell
, vol.124
, pp. 1241-1253
-
-
Betschinger, J.1
Mechtler, K.2
Knoblich, J.A.3
-
54
-
-
33646065651
-
Connecting cancer to the asymmetric division of stem cells
-
Wodarz A, Gonzalez C: Connecting cancer to the asymmetric division of stem cells. Cell 124, 1121-1123 (2006).
-
(2006)
Cell
, vol.124
, pp. 1121-1123
-
-
Wodarz, A.1
Gonzalez, C.2
-
55
-
-
27144555447
-
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
-
Caussinus E, Gonzalez C: Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster Nat. Genet. 37, 1125-1129 (2005).
-
(2005)
Nat. Genet
, vol.37
, pp. 1125-1129
-
-
Caussinus, E.1
Gonzalez, C.2
-
56
-
-
4043170088
-
Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors
-
Blider D: Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 18, 1909-1925 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 1909-1925
-
-
Blider, D.1
-
58
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
Prince ME, Sivanandan R, Kaczorowski A et al.: Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl Acad Sci. USA 104, 973-978 (2007).
-
(2007)
Proc. Natl Acad Sci. USA
, vol.104
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
-
59
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P et al.: Identification of pancreatic cancer stem cells. Cancer Res. 67, 1030-1037 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
60
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID et al.: Identification of human brain tumour initiating cells. Nature 432, 396-401 (2004).
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
61
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc. Natl Acad. Sci. USA 100, 3983-3988 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
62
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
Dalerba P, Dylla SJ, Park IK et al.: Phenotypic characterization of human colorectal cancer stem cells. Proc. Natl Acad. Sci. USA 104, 10158-10163 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.K.3
-
63
-
-
34250213859
-
DNA methylation as a therapeutic target in cancer
-
Issa JP: DNA methylation as a therapeutic target in cancer. Clin. Cancer Res. 13, 1634-1637 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1634-1637
-
-
Issa, J.P.1
-
64
-
-
0842281433
-
Therapeutic implications of cancer stem cells
-
Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF: Therapeutic implications of cancer stem cells. Curr. Opin. Genet. Dev. 14, 43-47 (2004).
-
(2004)
Curr. Opin. Genet. Dev
, vol.14
, pp. 43-47
-
-
Al-Hajj, M.1
Becker, M.W.2
Wicha, M.3
Weissman, I.4
Clarke, M.F.5
-
65
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB: The epigenomics of cancer. Cell 128, 683-692 (2007).
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
66
-
-
33847130464
-
Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients
-
Sonneman J, Gange J, Pilz S et al.: Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients. BMC Cancer 6, 183 (2006).
-
(2006)
BMC Cancer
, vol.6
, pp. 183
-
-
Sonneman, J.1
Gange, J.2
Pilz, S.3
-
67
-
-
33847677760
-
Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma
-
Kumar KS, Sonnemann J, Hong Le TT et al.: Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma. Anticancer Res. 27, 465-470 (2007).
-
(2007)
Anticancer Res
, vol.27
, pp. 465-470
-
-
Kumar, K.S.1
Sonnemann, J.2
Hong, L.T.3
-
68
-
-
34548299792
-
Combination of SK-7041, one of novel histone deacetylase inhibitors, and STI571-induced synergistic apoptosis in chronic myeloid leukemia
-
Kim BS, Bae E, Kim YJ et al.: Combination of SK-7041, one of novel histone deacetylase inhibitors, and STI571-induced synergistic apoptosis in chronic myeloid leukemia. Anticancer Drugs 18, 641-647 (2007).
-
(2007)
Anticancer Drugs
, vol.18
, pp. 641-647
-
-
Kim, B.S.1
Bae, E.2
Kim, Y.J.3
-
69
-
-
33744829728
-
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells
-
Wischnewski F. Pantel K, Schwarzenbach H: Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. Mol. Cancer Res. 4, 339-349 (2006).
-
(2006)
Mol. Cancer Res
, vol.4
, pp. 339-349
-
-
Wischnewski, F.1
Pantel, K.2
Schwarzenbach, H.3
-
70
-
-
34250634403
-
A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy
-
Karpf AR: A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy. Epigenetics 1, 116-120 (2006).
-
(2006)
Epigenetics
, vol.1
, pp. 116-120
-
-
Karpf, A.R.1
-
71
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo CB, Jones PA: Epigenetic therapy of cancer: past, present and future. Nat. Rev. Drug Discov. 5, 37-50 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
72
-
-
33750065136
-
Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer
-
Yuecheng Y, Hongmei L, Xiaoyan X: Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer. Clin. Exp. Metastasis 23, 65-74 (2006).
-
(2006)
Clin. Exp. Metastasis
, vol.23
, pp. 65-74
-
-
Yuecheng, Y.1
Hongmei, L.2
Xiaoyan, X.3
-
73
-
-
1642289104
-
5-aza-2′-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis
-
Nam JS, Ino Y, Kanai Y, Sakamoto M, Hirohashi S: 5-aza-2′-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis. Clin. Exp. Metastasis 21, 49-56 (2004).
-
(2004)
Clin. Exp. Metastasis
, vol.21
, pp. 49-56
-
-
Nam, J.S.1
Ino, Y.2
Kanai, Y.3
Sakamoto, M.4
Hirohashi, S.5
-
74
-
-
0035829016
-
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells
-
Si HX, Tsao SW, Lam KY et al.: E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells. Cancer Lett. 173, 71-78 (2001).
-
(2001)
Cancer Lett
, vol.173
, pp. 71-78
-
-
Si, H.X.1
Tsao, S.W.2
Lam, K.Y.3
-
76
-
-
34648846599
-
Trichostatin A, a histone deacetylase inhibitor, attenuates invasiveness and reactivates E-cadherin expression in immortalized endometriotic cells
-
Wu Y, Starzinski-Powitz A, Guo SW: Trichostatin A, a histone deacetylase inhibitor, attenuates invasiveness and reactivates E-cadherin expression in immortalized endometriotic cells. Reprod. Sci. 14, 374-382 (2007).
-
(2007)
Reprod. Sci
, vol.14
, pp. 374-382
-
-
Wu, Y.1
Starzinski-Powitz, A.2
Guo, S.W.3
-
77
-
-
33845976704
-
Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-β1 in human renal epithelial cells
-
Yoshikawa M, Hishikawa K, Marumo T, Fujita T: Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-β1 in human renal epithelial cells. J. Am. Soc. Nephrol. 18, 58-65 (2007).
-
(2007)
J. Am. Soc. Nephrol
, vol.18
, pp. 58-65
-
-
Yoshikawa, M.1
Hishikawa, K.2
Marumo, T.3
Fujita, T.4
-
78
-
-
34250810709
-
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells
-
Kumagai T, Wakimoto N, Yin D et al.: Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. Int. J. Cancer 121, 656-665 (2007).
-
(2007)
Int. J. Cancer
, vol.121
, pp. 656-665
-
-
Kumagai, T.1
Wakimoto, N.2
Yin, D.3
-
79
-
-
1042267223
-
Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells
-
Takai N, Desmond JC, Kumagai T et al.: Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells. Clin. Cancer Res. 10, 1141-1149 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 1141-1149
-
-
Takai, N.1
Desmond, J.C.2
Kumagai, T.3
-
80
-
-
33847796188
-
Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cells
-
Ueda T, Takai N, Nishida M, Nasu K, Narahara H: Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cells. Int. J. Mol. Med. 19, 301-308 (2007).
-
(2007)
Int. J. Mol. Med
, vol.19
, pp. 301-308
-
-
Ueda, T.1
Takai, N.2
Nishida, M.3
Nasu, K.4
Narahara, H.5
-
81
-
-
0001056246
-
Butyrate- but not TGFβ1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase
-
Butt AJ, Hague A, Paraskeva C: Butyrate- but not TGFβ1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase. Cell Death Differ. 4, 725-732 (1997).
-
(1997)
Cell Death Differ
, vol.4
, pp. 725-732
-
-
Butt, A.J.1
Hague, A.2
Paraskeva, C.3
-
82
-
-
0033986784
-
Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells
-
Barshishat M, Polak-Charcon S, Schwartz B: Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells. Br. J. Cancer 82, 195-203 (2000).
-
(2000)
Br. J. Cancer
, vol.82
, pp. 195-203
-
-
Barshishat, M.1
Polak-Charcon, S.2
Schwartz, B.3
-
83
-
-
0038676409
-
Inhibition of histone deacetylase activity by butyrate
-
Davie JR: Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133, S2485-S2493 (2003).
-
(2003)
J. Nutr
, vol.133
-
-
Davie, J.R.1
-
84
-
-
33846228427
-
Valproic acid: Second generation
-
Bialer M, Yagen B: Valproic acid: second generation. Neurotherapeutics 4, 130-137 (2007).
-
(2007)
Neurotherapeutics
, vol.4
, pp. 130-137
-
-
Bialer, M.1
Yagen, B.2
-
85
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB: Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21, 103-107 (1999).
-
(1999)
Nat. Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
|