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Volumn 27, Issue 2, 2008, Pages 169-178

The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancer

Author keywords

Cancer; Oxidative stress; Phosphatase; PP5

Indexed keywords

GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 90; HORMONE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN P53; PROTEIN PHOSPHATASE 5; RAC PROTEIN; RAF PROTEIN; RAS PROTEIN; SERINE PROTEINASE; THREONINE PROTEINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 43049097815     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-008-9125-z     Document Type: Review
Times cited : (76)

References (75)
  • 1
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts, P. J., & Der, C. J. (2007). Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene, 26, 3291-3310.
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 2
    • 34250165729 scopus 로고    scopus 로고
    • Downstream intracellular effectors of epidermal growth factor receptor as targets for anticancer therapy
    • Milano, A., De Rosa, V., Iaffaioli, R. V., & Caponigro, F. (2007). Downstream intracellular effectors of epidermal growth factor receptor as targets for anticancer therapy. Expert Opinion on Therapeutic Targets, 11, 771-782.
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , pp. 771-782
    • Milano, A.1    De Rosa, V.2    Iaffaioli, R.V.3    Caponigro, F.4
  • 3
    • 34447502203 scopus 로고    scopus 로고
    • DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis
    • 6
    • Schmitt, E., Paquet, C., Beauchemin, M., & Bertrand, R. (2007). DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis. Journal of Zhejiang University Science B, 8(6), 377-397.
    • (2007) Journal of Zhejiang University Science B , vol.8 , pp. 377-397
    • Schmitt, E.1    Paquet, C.2    Beauchemin, M.3    Bertrand, R.4
  • 5
    • 0036667397 scopus 로고    scopus 로고
    • Serine/threonine protein phosphatases in apoptosis
    • 4
    • Klumpp, S., & Krieglstein, J. (2002). Serine/threonine protein phosphatases in apoptosis. Current Opinion in Pharmacology, 2(4), 458-462.
    • (2002) Current Opinion in Pharmacology , vol.2 , pp. 458-462
    • Klumpp, S.1    Krieglstein, J.2
  • 6
    • 0037081563 scopus 로고    scopus 로고
    • Protein phosphatase 1-targeted in many directions
    • Pt 2
    • Cohen, P. T. (2002). Protein phosphatase 1-targeted in many directions. Journal of Cell Science, 115(Pt 2), 241-256.
    • (2002) Journal of Cell Science , vol.115 , pp. 241-256
    • Cohen, P.T.1
  • 7
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • Cohen, P. (1989). The structure and regulation of protein phosphatases. Annual Review of Biochemistry, 58, 453-508.
    • (1989) Annual Review of Biochemistry , vol.58 , pp. 453-508
    • Cohen, P.1
  • 8
    • 0030790128 scopus 로고    scopus 로고
    • Novel protein serine/threonine phosphatases: Variety is the spice of life
    • 7
    • Cohen, P. T. (1997). Novel protein serine/threonine phosphatases: Variety is the spice of life. Trends in Biochemical Sciences, 22(7), 245-251.
    • (1997) Trends in Biochemical Sciences , vol.22 , pp. 245-251
    • Cohen, P.T.1
  • 9
    • 0025313882 scopus 로고
    • Serine/threonine protein phosphatases: An expanding family
    • Cohen, P. T. W., Brewis, N. D., Hughes, V., & Mann, D. J. (1990). Serine/threonine protein phosphatases: An expanding family. FEBS Letters, 268, 355-358.
    • (1990) FEBS Letters , vol.268 , pp. 355-358
    • Cohen, P.T.W.1    Brewis, N.D.2    Hughes, V.3    Mann, D.J.4
  • 10
    • 0025996058 scopus 로고
    • Cloning of protein-serine/threonine phosphatases
    • Cohen, P. T. W. (1991). Cloning of protein-serine/threonine phosphatases. Methods in Enzymology, 201, 398-408.
    • (1991) Methods in Enzymology , vol.201 , pp. 398-408
    • Cohen, P.T.W.1
  • 11
    • 0024977379 scopus 로고
    • A suppressor of HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases
    • Arndt, K. T., Styles, C. A., & Fink, G. R. (1989). A suppressor of HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases. Cell, 56, 527-537.
    • (1989) Cell , vol.56 , pp. 527-537
    • Arndt, K.T.1    Styles, C.A.2    Fink, G.R.3
  • 12
    • 0032524677 scopus 로고    scopus 로고
    • Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21WAF1/Cip1 and mediate growth arrest
    • 20
    • Zhuang, Z., Dean, N. M., & Honkanen, R. E. (1998). Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21WAF1/Cip1 and mediate growth arrest. Journal of Biological Chemistry, 273(20), 12250-12258.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 12250-12258
    • Zhuang, Z.1    Dean, N.M.2    Honkanen, R.E.3
  • 13
    • 0030921056 scopus 로고    scopus 로고
    • Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin
    • 26
    • Silverstein, A. M., Galigniana, M. D., Chen, M. S., Owens-Grillo, J. K., Chinkers, M., & Pratt, W. B. (1997). Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. Journal of Biological Chemistry, 272(26), 16224-16230.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 16224-16230
    • Silverstein, A.M.1    Galigniana, M.D.2    Chen, M.S.3    Owens-Grillo, J.K.4    Chinkers, M.5    Pratt, W.B.6
  • 14
    • 0030928118 scopus 로고    scopus 로고
    • Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5
    • Skinner, J., Sinclair, C., Romeo, C., Armstrong, D., Charbonneau, H., & Rossie, S. (1997). Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5. Journal of Biological Chemistry, 272, 22464-22471.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 22464-22471
    • Skinner, J.1    Sinclair, C.2    Romeo, C.3    Armstrong, D.4    Charbonneau, H.5    Rossie, S.6
  • 15
    • 0031572314 scopus 로고    scopus 로고
    • Genomic organization of the human PP4 gene encoding a serine/threonine protein phosphatase (PP4) suggest a common ancestry with PP2A
    • Huang, X., Cheng, A., & Honkanen, R. E. (1997). Genomic organization of the human PP4 gene encoding a serine/threonine protein phosphatase (PP4) suggest a common ancestry with PP2A. Genomics, 44, 336-343.
    • (1997) Genomics , vol.44 , pp. 336-343
    • Huang, X.1    Cheng, A.2    Honkanen, R.E.3
  • 16
    • 0030475875 scopus 로고    scopus 로고
    • The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation
    • Pt 12
    • Bastians, H., & Ponstingl, H. (1996). The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation. Journal of Cell Science, 109(Pt 12), 2865-2874.
    • (1996) Journal of Cell Science , vol.109 , pp. 2865-2874
    • Bastians, H.1    Ponstingl, H.2
  • 17
    • 0031915128 scopus 로고    scopus 로고
    • Molecular cloning, expression and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)
    • 3
    • Huang, X., & Honkanen, R. E. (1998). Molecular cloning, expression and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC). Journal of Biological Chemistry, 273(3), 1462-1468.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 1462-1468
    • Huang, X.1    Honkanen, R.E.2
  • 18
    • 4043101125 scopus 로고    scopus 로고
    • Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5
    • 32
    • Swingle, M. R., Honkanen, R. E., & Ciszak, E. M. (2004). Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5. Journal of Biological Chemistry, 279(32), 33992-33999.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 33992-33999
    • Swingle, M.R.1    Honkanen, R.E.2    Ciszak, E.M.3
  • 20
    • 0025898450 scopus 로고
    • Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain
    • 10
    • Honkanen, R. E., Zwiller, J., Daily, S. L., Khatra, B. S., Dukelow, M., & Boynton, A. L. (1991). Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain. Journal of Biological Chemistry, 266(10), 6614-6619.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 6614-6619
    • Honkanen, R.E.1    Zwiller, J.2    Daily, S.L.3    Khatra, B.S.4    Dukelow, M.5    Boynton, A.L.6
  • 21
    • 0028023078 scopus 로고
    • Molecular cloning of a protein serine threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain
    • Becker, W., Kentrup, H., Klumpp, S., Schultz, J. E., & Joost, H. G. (1994). Molecular cloning of a protein serine threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain. Journal of Biological Chemistry, 269, 22586-22592.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 22586-22592
    • Becker, W.1    Kentrup, H.2    Klumpp, S.3    Schultz, J.E.4    Joost, H.G.5
  • 22
    • 0028133445 scopus 로고
    • A novel human serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus
    • 18
    • Chen, M. X., McPartlin, A. E., Brown, L., Chen, Y. H., Barker, H. M., & Cohen, P. T. W. (1994). A novel human serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. The EMBO Journal, 13(18), 4278-4290.
    • (1994) The EMBO Journal , vol.13 , pp. 4278-4290
    • Chen, M.X.1    McPartlin, A.E.2    Brown, L.3    Chen, Y.H.4    Barker, H.M.5    Cohen, P.T.W.6
  • 23
    • 0028117770 scopus 로고
    • Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor
    • Chinkers, M. (1994). Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor. Proceedings of the National Academy of Sciences of the United States of America, 91, 11075-11079.
    • (1994) Proceedings of the National Academy of Sciences of the United States of America , vol.91 , pp. 11075-11079
    • Chinkers, M.1
  • 25
    • 0029751136 scopus 로고    scopus 로고
    • The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant
    • Chen, M. S., Silverstein, A. M., Pratt, W. B., & Chinkers, M. (1996). The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant. Journal of Biological Chemistry, 271, 32315-32320.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 32315-32320
    • Chen, M.S.1    Pratt, W.B.2    Silverstein, A.M.3    Chinkers, M.4
  • 26
    • 13544267438 scopus 로고    scopus 로고
    • Differential control of glucocorticoid receptor hormone-binding function by tetratricopeptide repeat (TPR) proteins and the immunosuppressive ligand FK506
    • Davies, T. H., Ning, Y. M., & Sanchez, E. R. (2005). Differential control of glucocorticoid receptor hormone-binding function by tetratricopeptide repeat (TPR) proteins and the immunosuppressive ligand FK506. Biochemistry, 44, 2030-2038.
    • (2005) Biochemistry , vol.44 , pp. 2030-2038
    • Davies, T.H.1    Ning, Y.M.2    Sanchez, E.R.3
  • 27
    • 0031437422 scopus 로고    scopus 로고
    • The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex
    • 51
    • Ollendorff, V., & Donoghue, D. J. (1997). The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex. Journal of Biological Chemistry, 272(51), 32011-32018.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 32011-32018
    • Ollendorff, V.1    Donoghue, D.J.2
  • 28
    • 0031266991 scopus 로고    scopus 로고
    • Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity
    • Zhao, S., & Sancar, A. (1997). Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity. Photochemistry and Photobiology, 66, 727-731.
    • (1997) Photochemistry and Photobiology , vol.66 , pp. 727-731
    • Zhao, S.1    Sancar, A.2
  • 29
    • 0037188421 scopus 로고    scopus 로고
    • Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase
    • Shao, J., Hartson, S. D., & Matts, R. L. (2002). Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase. Biochemistry, 41, 6770-6779.
    • (2002) Biochemistry , vol.41 , pp. 6770-6779
    • Shao, J.1    Hartson, S.D.2    Matts, R.L.3
  • 30
    • 0035503696 scopus 로고    scopus 로고
    • Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
    • Morita, K., Saitoh, M., Tobiume, K., Matsuura, H., Enomoto, S., Nishitoh, H., et al. (2001). Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. The EMBO Journal, 20, 6028-6036.
    • (2001) The EMBO Journal , vol.20 , pp. 6028-6036
    • Morita, K.1    Saitoh, M.2    Tobiume, K.3    Matsuura, H.4    Enomoto, S.5    Nishitoh, H.6
  • 32
    • 1042301303 scopus 로고    scopus 로고
    • Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
    • Ali, A., Zhang, J., Bao, S., Liu, I., Otterness, D., Dean, N. M., et al. (2004). Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. Genes and Development, 18, 249-254.
    • (2004) Genes and Development , vol.18 , pp. 249-254
    • Ali, A.1    Zhang, J.2    Bao, S.3    Liu, I.4    Otterness, D.5    Dean, N.M.6
  • 34
    • 0035914309 scopus 로고    scopus 로고
    • Interaction between protein phosphatase 5 and the a subunit of protein phosphatase 2A: Evidence for a heterotrimeric form of protein phosphatase 5
    • 42
    • Lubert, E. J., Hong, Y., & Sarge, K. D. (2001). Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: Evidence for a heterotrimeric form of protein phosphatase 5. Journal of Biological Chemistry, 276(42), 38582-38587.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 38582-38587
    • Lubert, E.J.1    Hong, Y.2    Sarge, K.D.3
  • 35
    • 0037031156 scopus 로고    scopus 로고
    • Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
    • Yamaguchi, Y., Katoh, H., Mori, K., & Negishi, M. (2002). Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Current Biology, 12, 1353.
    • (2002) Current Biology , vol.12 , pp. 1353
    • Yamaguchi, Y.1    Katoh, H.2    Mori, K.3    Negishi, M.4
  • 39
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • Pratt, W. B., & Toft, D. O. (1997). Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocrine Reviews, 18, 306-360.
    • (1997) Endocrine Reviews , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 40
    • 0031106603 scopus 로고    scopus 로고
    • Chaperones get in touch: The Hip-Hop connection
    • Frydman, J., & Höhfeld, J. (1997). Chaperones get in touch: The Hip-Hop connection. Trends in Biochemical Sciences, 22, 87-92.
    • (1997) Trends in Biochemical Sciences , vol.22 , pp. 87-92
    • Frydman, J.1    Höhfeld, J.2
  • 41
    • 0040370216 scopus 로고    scopus 로고
    • Ser/thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest
    • 28
    • Zuo, Z., Urban, G., Scammell, J. G., Dean, N. M., McLean, T. K., Aragon, I. V., et al. (1999). Ser/thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. Biochemistry, 38(28), 8849-8857.
    • (1999) Biochemistry , vol.38 , pp. 8849-8857
    • Zuo, Z.1    Urban, G.2    Scammell, J.G.3    Dean, N.M.4    McLean, T.K.5    Aragon, I.V.6
  • 42
    • 2342666137 scopus 로고    scopus 로고
    • Serine/threonine phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling
    • 6
    • Dean, D. A., Urban, G., Aragon, I. V., Swingle, M., Miller, B., Rusconi, S., et al. (2001). Serine/threonine phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling. BMC Cell Biology, 2(6), 1471-2121.
    • (2001) BMC Cell Biology , vol.2 , pp. 1471-2121
    • Dean, D.A.1    Urban, G.2    Aragon, I.V.3    Swingle, M.4    Miller, B.5    Rusconi, S.6
  • 44
    • 0033712280 scopus 로고    scopus 로고
    • Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding
    • Denny, W. B., Valentine, D. L., Reynolds, P. D., Smith, D. F., & Scammell, J. G. (2000). Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding. Endocrinology, 141, 4107-4113.
    • (2000) Endocrinology , vol.141 , pp. 4107-4113
    • Denny, W.B.1    Valentine, D.L.2    Reynolds, P.D.3    Smith, D.F.4    Scammell, J.G.5
  • 45
    • 0037085381 scopus 로고    scopus 로고
    • A new first step in activation of steroid receptors: Hormone-induced switching of FKBP51 and FKBP52 immunophilins
    • Davies, T. H., Ning, Y. M., & Sanchez, E. R. (2002). A new first step in activation of steroid receptors: Hormone-induced switching of FKBP51 and FKBP52 immunophilins. Journal of Biological Chemistry, 277, 4597-4600.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 4597-4600
    • Davies, T.H.1    Ning, Y.M.2    Sanchez, E.R.3
  • 46
    • 33847198615 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by C-terminal-associated protein phosphatase
    • Wang, Z., Chen, W., Kono, E., Dang, T., & Garabedian, M. J. (2007). Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by C-terminal-associated protein phosphatase. Molecular Endocrinology, 21, 625-634.
    • (2007) Molecular Endocrinology , vol.21 , pp. 625-634
    • Wang, Z.1    Chen, W.2    Kono, E.3    Dang, T.4    Garabedian, M.J.5
  • 48
    • 0042318859 scopus 로고    scopus 로고
    • Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARbeta activity
    • 36
    • Sumanasekera, W. K., Tien, E. S., Davis, J. W., II, Turpey, R., Perdew, G. H., & Vanden Heuvel, J. P. (2003). Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARbeta activity. Biochemistry, 42(36), 10726-10735.
    • (2003) Biochemistry , vol.42 , pp. 10726-10735
    • Sumanasekera, W.K.1    Tien, E.S.2    Davis II, J.W.3    Turpey, R.4    Perdew, G.H.5    Vanden Heuvel, J.P.6
  • 49
    • 0033669662 scopus 로고    scopus 로고
    • Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2
    • 3
    • Meyer, B. K., Petrulis, J. R., & Perdew, J. H. (2000). Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2. Cell Stress Chaperones, 5(3), 243-254.
    • (2000) Cell Stress Chaperones , vol.5 , pp. 243-254
    • Meyer, B.K.1    Petrulis, J.R.2    Perdew, J.H.3
  • 50
    • 0032524677 scopus 로고    scopus 로고
    • Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21WAF1/Cip1 and mediate growth arrest
    • Zuo, Z., Dean, N. M., & Honkanen, R. E. (1998). Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21WAF1/Cip1 and mediate growth arrest. Journal of Biological Chemistry, 273, 12250-12258.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 12250-12258
    • Zuo, Z.1    Dean, N.M.2    Honkanen, R.E.3
  • 51
    • 0038660681 scopus 로고    scopus 로고
    • Identification of a functional link for the p53-tumor suppressor protein in dexamethasone induced growth suppression
    • 11
    • Urban, G., Golden, T., Aragon, I. V., Cowsert, L., Cooper, S. R., Dean, N. M., et al. (2003). Identification of a functional link for the p53-tumor suppressor protein in dexamethasone induced growth suppression. Journal of Biological Chemistry, 278(11), 9747-9753.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 9747-9753
    • Urban, G.1    Golden, T.2    Aragon, I.V.3    Cowsert, L.4    Cooper, S.R.5    Dean, N.M.6
  • 52
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. (1996). Cancer cell cycles. Science, 274, 1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 53
    • 0035827335 scopus 로고    scopus 로고
    • A p53 Amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation
    • Zhang, Y., & Xiong, Y. (2001). A p53 Amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation. Science, 292, 1910-1915.
    • (2001) Science , vol.292 , pp. 1910-1915
    • Zhang, Y.1    Xiong, Y.2
  • 54
    • 0035280982 scopus 로고    scopus 로고
    • Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV
    • Bean, L. J., & Stark, G. R. (2001). Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV. Oncogene, 20, 1076-1084.
    • (2001) Oncogene , vol.20 , pp. 1076-1084
    • Bean, L.J.1    Stark, G.R.2
  • 55
    • 0037039158 scopus 로고    scopus 로고
    • Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel
    • Storey, N. M., O'Bryan, J. P., & Armstrong, D. L. (2002). Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel. Current Biology, 12, 27-33.
    • (2002) Current Biology , vol.12 , pp. 27-33
    • Storey, N.M.1    O'Bryan, J.P.2    Armstrong, D.L.3
  • 57
    • 0035920229 scopus 로고    scopus 로고
    • Identification of an Estrogen-inducible Phosphatase (PP5) that converts MCF-7 Human Breast Carcinoma Cells into an Estrogen-Independent phenotype when expressed constitutively
    • 29
    • Urban, G., Golden, T., Aragon, I. V., Scammell, J. G., Dean, N. M., & Honkanen, R. E. (2001). Identification of an Estrogen-inducible Phosphatase (PP5) that converts MCF-7 Human Breast Carcinoma Cells into an Estrogen-Independent phenotype when expressed constitutively. Journal of Biological Chemistry, 276(29), 27638-27646.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 27638-27646
    • Urban, G.1    Golden, T.2    Aragon, I.V.3    Scammell, J.G.4    Dean, N.M.5    Honkanen, R.E.6
  • 58
    • 2342573676 scopus 로고    scopus 로고
    • Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription
    • Ikeda, k., Ogawa, S., Tsukui, T., Horie-Inoue, K., Ouchi, Y., Kato, S., et al. (2004). Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription. Molecular Endocrinology, 18, 1131-1143.
    • (2004) Molecular Endocrinology , vol.18 , pp. 1131-1143
    • Ikeda, K.1    Ogawa, S.2    Tsukui, T.3    Horie-Inoue, K.4    Ouchi, Y.5    Kato, S.6
  • 59
    • 4544233003 scopus 로고    scopus 로고
    • Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice
    • Golden, T., Aragon, I. V., Zhou, G., Cooper, S. R., Dean, N. M., & Honkanen, R. E. (2004). Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice. Cancer Letters, 215, 95-100.
    • (2004) Cancer Letters , vol.215 , pp. 95-100
    • Golden, T.1    Aragon, I.V.2    Zhou, G.3    Cooper, S.R.4    Dean, N.M.5    Honkanen, R.E.6
  • 60
    • 8744271485 scopus 로고    scopus 로고
    • Ser/thr protein phosphatase 5 (PP5) inactivates hypoxia-induced activation of an ASK-1/MKK-4/JNK-signaling cascade
    • Zhou, G., Golden, T., Aragon, I. V., & Honkanen, R. E. (2004). Ser/thr protein phosphatase 5 (PP5) inactivates hypoxia-induced activation of an ASK-1/MKK-4/JNK-signaling cascade. Journal of Biological Chemistry, 279, 46595-46605.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 46595-46605
    • Zhou, G.1    Golden, T.2    Aragon, I.V.3    Honkanen, R.E.4
  • 62
    • 0036019933 scopus 로고    scopus 로고
    • Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice
    • Matsuzawa, A., Nishitoh, H., Tobiume, K., Takeda, K., & Ichijo, H. (2002). Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice. Antioxidants and Redox Signalling, 4, 415-425.
    • (2002) Antioxidants and Redox Signalling , vol.4 , pp. 415-425
    • Matsuzawa, A.1    Nishitoh, H.2    Tobiume, K.3    Takeda, K.4    Ichijo, H.5
  • 63
    • 4344610451 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity
    • Huang, S., Shu, L., Easton, J., Harwood, F. C., Germain, G. S., Ichijo, H., et al. (2004). Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity. Journal of Biological Chemistry, 279, 36490-36496.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 36490-36496
    • Huang, S.1    Shu, L.2    Easton, J.3    Harwood, F.C.4    Germain, G.S.5    Ichijo, H.6
  • 64
    • 0034162719 scopus 로고    scopus 로고
    • DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus
    • DiBiase, S. J., Zeng, Z.-C., Chen, R., Hyslop, T., Curran, W. J., Jr., & Iliakis, G. (2000). DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. Canadian Research, 60, 1245-1253.
    • (2000) Canadian Research , vol.60 , pp. 1245-1253
    • Dibiase, S.J.1    Zeng, Z.-C.2    Chen, R.3    Hyslop, T.4    Curran Jr., W.J.5    Iliakis, G.6
  • 65
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham, R. T. (2001). Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes and Development, 15, 2177-2196.
    • (2001) Genes and Development , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 66
    • 34447525646 scopus 로고    scopus 로고
    • Mice lacking protein phosphatase5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest
    • Yong, W., Bao, S., Chen, H., Dapei, L., Sanchez, E. R., & Shou, W. (2007). Mice lacking protein phosphatase5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest. Journal of Biological Chemistry, 282, 14690-14694.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 14690-14694
    • Yong, W.1    Bao, S.2    Chen, H.3    Dapei, L.4    Sanchez, E.R.5    Shou, W.6
  • 67
    • 2342667394 scopus 로고    scopus 로고
    • Characterization of Saccharomyces cerevisiae protein Ser/Thr phosphatase T1 and comparison to its mammalian homolog PP5
    • Jeong, J.-Y., Johns, J., Sinclair, C., Park, J.-M., & Rossie, S. (2003). Characterization of Saccharomyces cerevisiae protein Ser/Thr phosphatase T1 and comparison to its mammalian homolog PP5. BMC Cell Biology, 4, 3.
    • (2003) BMC Cell Biology , vol.4 , pp. 3
    • Jeong, J.-Y.1    Johns, J.2    Sinclair, C.3    Park, J.-M.4    Rossie, S.5
  • 71
    • 34147138082 scopus 로고    scopus 로고
    • Mitelman, F., Johansson, B., Mertens, F. (Eds.)
    • Mitelman, F., Johansson, B., Mertens, F. (Eds.) (2007). Mitelman database of chromosome aberrations in cancer. http://cgap.nci.nih.gov/Chromosomes/ Mitelman
    • (2007) Mitelman Database of Chromosome Aberrations in Cancer
  • 72
    • 0038286174 scopus 로고    scopus 로고
    • The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases
    • Lad, C., Williams, N. H., & Wolfenden, R. (2003). The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases. Proceedings of the National Academy of Sciences of the United States of America, 100, 5607-5610.
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , pp. 5607-5610
    • Lad, C.1    Williams, N.H.2    Wolfenden, R.3
  • 74
    • 0029133116 scopus 로고
    • X-ray structure of calcineurin inhibited by the immunophilin- immunosuppressant FKBP12-FK506 complex
    • Griffith, J. P., Kim, J. L., Kim, E. E., Sintchak, M. D., Thomson, J. A., Fitzgibbon, M. J., et al. (1995). X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Cell, 82, 507-522.
    • (1995) Cell , vol.82 , pp. 507-522
    • Griffith, J.P.1    Kim, J.L.2    Kim, E.E.3    Sintchak, M.D.4    Thomson, J.A.5    Fitzgibbon, M.J.6


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