Determination of protein-ligand binding modes using complexation-induced changes in 1H NMR chemical shift

Journal of Medicinal Chemistry

Volumn 51, Issue 8, 2008, Pages 2512-2517

  Ciofli, Marina ^a   Hunter, Christopher A ^a   Packer, Martin J ^b   Spitaleri, Andrea ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ZINOSTATIN;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; GENETIC ALGORITHM; LIGAND BINDING; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; VALIDATION PROCESS;

CRYSTALLOGRAPHY, X-RAY; LIGANDS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEINS;

EID: 43049083331     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm701194r     Document Type: Article

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