-
1
-
-
0142105914
-
Cholesterol: From heart attacks to Alzheimer's disease
-
Raffai, R. L., and Weisgraber, K. H. (2003) Cholesterol: From heart attacks to Alzheimer's disease. J. Lipid Res. 44, 1423-1430.
-
(2003)
J. Lipid Res
, vol.44
, pp. 1423-1430
-
-
Raffai, R.L.1
Weisgraber, K.H.2
-
2
-
-
0023900109
-
Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains
-
Wetterau, J. R., Aggerbeck, L. P., Rall, S. C., Jr., and Weisgraber, K. H. (1988) Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains. J. Biol. Chem. 263, 6240-6248.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 6240-6248
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Rall Jr., S.C.3
Weisgraber, K.H.4
-
3
-
-
0028303072
-
Apolipoprotein E: Structure-function relationships
-
Weisgraber, K. H. (1994) Apolipoprotein E: Structure-function relationships. Adv. Protein Chem. 45, 249-302.
-
(1994)
Adv. Protein Chem
, vol.45
, pp. 249-302
-
-
Weisgraber, K.H.1
-
4
-
-
3242656580
-
Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins
-
Saito, H., Lund-Katz, S., and Phillips, M. C. (2004) Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins. Prog. Lipid Res. 43, 350-380.
-
(2004)
Prog. Lipid Res
, vol.43
, pp. 350-380
-
-
Saito, H.1
Lund-Katz, S.2
Phillips, M.C.3
-
5
-
-
0035834416
-
CNS synaptogenesis promoted by glia-derived cholesterol
-
Mauch, D. H., Nagler, K., Schumacher, S., Goritz, C., Muller, E. C., Otto, A., and Pfrieger, F. W. (2001) CNS synaptogenesis promoted by glia-derived cholesterol. Science 294, 1354-1357.
-
(2001)
Science
, vol.294
, pp. 1354-1357
-
-
Mauch, D.H.1
Nagler, K.2
Schumacher, S.3
Goritz, C.4
Muller, E.C.5
Otto, A.6
Pfrieger, F.W.7
-
6
-
-
0026523122
-
The amphipathic helix in the exchangeable apolipoproteins: A review of secondary structure and function
-
Segrest, J. P., Jones, M. K., De Loof, H., Brouillette, C. G., Venkatachalapathi, Y. V., and Anantharamaiah, G. M. (1992) The amphipathic helix in the exchangeable apolipoproteins: A review of secondary structure and function. J. Lipid Res. 33, 141-166.
-
(1992)
J. Lipid Res
, vol.33
, pp. 141-166
-
-
Segrest, J.P.1
Jones, M.K.2
De Loof, H.3
Brouillette, C.G.4
Venkatachalapathi, Y.V.5
Anantharamaiah, G.M.6
-
7
-
-
0142138664
-
Pathogenesis of cerebral amyloid angiopathy
-
Rensink, A. A., de Waal, R. M., Kremer, B., and Verbeek, M. M. (2003) Pathogenesis of cerebral amyloid angiopathy. Brain Res. 43, 207-223.
-
(2003)
Brain Res
, vol.43
, pp. 207-223
-
-
Rensink, A.A.1
de Waal, R.M.2
Kremer, B.3
Verbeek, M.M.4
-
8
-
-
0032211830
-
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe, D. J. (1998) The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8, 447-453.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
9
-
-
0038117796
-
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
-
Naslund, J., Haroutunian, V., Mohs, R., Davis, K. L., Davies, P., Greengard, P., and Buxbaum, J. D. (2000) Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline. J. Am. Med. Assoc. 283, 1571-1577.
-
(2000)
J. Am. Med. Assoc
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
Buxbaum, J.D.7
-
10
-
-
0036708168
-
Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: The emerging role of oligomeric assemblies
-
Kirkitadze, M. D., Bitan, G., and Teplow, D. B. (2002) Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: The emerging role of oligomeric assemblies. J. Neurosci. Res. 69, 567-577.
-
(2002)
J. Neurosci. Res
, vol.69
, pp. 567-577
-
-
Kirkitadze, M.D.1
Bitan, G.2
Teplow, D.B.3
-
11
-
-
4143091289
-
Apolipoprotein E: Diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease
-
Huang, Y., Weisgraber, K. H., Mucke, L., and Mahley, R. W. (2004) Apolipoprotein E: Diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease. J. Mol. Neurosci. 23, 189-204.
-
(2004)
J. Mol. Neurosci
, vol.23
, pp. 189-204
-
-
Huang, Y.1
Weisgraber, K.H.2
Mucke, L.3
Mahley, R.W.4
-
12
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W. J., Saunders, A. M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G. S., and Roses, A. D. (1993) Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90, 1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
13
-
-
12044254746
-
-
Strittmatter, W. J., Weisgraber, K. H., Huang, D. Y., Dong, L. M., Salvesen, G. S., Pericak-Vance, M., Schmechel, D., Saunders, A. M., Goldgaber, D., and Roses, A. D. (1993) Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90, 8098-8102.
-
Strittmatter, W. J., Weisgraber, K. H., Huang, D. Y., Dong, L. M., Salvesen, G. S., Pericak-Vance, M., Schmechel, D., Saunders, A. M., Goldgaber, D., and Roses, A. D. (1993) Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90, 8098-8102.
-
-
-
-
14
-
-
0028026587
-
Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
-
Sanan, D. A., Weisgraber, K. H., Russell, S. J., Mahley, R. W., Huang, D., Saunders, A., Schmechel, D., Wisniewski, T., Frangione, B., and Roses, A. D. (1994) Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J. Clin. Invest. 94, 860-869.
-
(1994)
J. Clin. Invest
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
Schmechel, D.7
Wisniewski, T.8
Frangione, B.9
Roses, A.D.10
-
15
-
-
0029905421
-
Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide Aβ
-
Chan, W., Fornwald, J., Brawner, M., and Wetzel, R. (1996) Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide Aβ. Biochemistry 35, 7123-7130.
-
(1996)
Biochemistry
, vol.35
, pp. 7123-7130
-
-
Chan, W.1
Fornwald, J.2
Brawner, M.3
Wetzel, R.4
-
16
-
-
0029754637
-
Alzheimer amyloid-β peptide forms denaturant-resistant complex with type ε3 but not type ε4 isoform of native apolipoprotein E
-
Zhou, Z., Smith, J. D., Greengard, P., and Gandy, S. (1996) Alzheimer amyloid-β peptide forms denaturant-resistant complex with type ε3 but not type ε4 isoform of native apolipoprotein E. Mol. Med. 2, 175-180.
-
(1996)
Mol. Med
, vol.2
, pp. 175-180
-
-
Zhou, Z.1
Smith, J.D.2
Greengard, P.3
Gandy, S.4
-
17
-
-
0030867936
-
Interaction of nascent apoE2, apoE3, and apoE4 isoforms expressed in mammalian cells with amyloid peptide β (1-40). Relevance to Alzheimer's disease
-
Aleshkov, S., Abraham, C. R., and Zannis, V. I. (1997) Interaction of nascent apoE2, apoE3, and apoE4 isoforms expressed in mammalian cells with amyloid peptide β (1-40). Relevance to Alzheimer's disease. Biochemistry 36, 10571-10580.
-
(1997)
Biochemistry
, vol.36
, pp. 10571-10580
-
-
Aleshkov, S.1
Abraham, C.R.2
Zannis, V.I.3
-
18
-
-
0034214329
-
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides
-
Tokuda, T., Calero, M., Matsubara, E., Vidal, R., Kumar, A., Permanne, B., Zlokovic, B., Smith, J. D., Ladu, M. J., Rostagno, A., Frangione, B., and Ghiso, J. (2000) Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides. Biochem. J. 348, 359-365.
-
(2000)
Biochem. J
, vol.348
, pp. 359-365
-
-
Tokuda, T.1
Calero, M.2
Matsubara, E.3
Vidal, R.4
Kumar, A.5
Permanne, B.6
Zlokovic, B.7
Smith, J.D.8
Ladu, M.J.9
Rostagno, A.10
Frangione, B.11
Ghiso, J.12
-
19
-
-
0028894661
-
Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the α2-macroglobulin receptor/low-density- lipoprotein receptor-related protein
-
Rebeck, G. W., Harr, S. D., Strickland, D. K., and Hyman, B. T. (1995) Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the α2-macroglobulin receptor/low-density- lipoprotein receptor-related protein. Ann. Neurol. 37, 211-217.
-
(1995)
Ann. Neurol
, vol.37
, pp. 211-217
-
-
Rebeck, G.W.1
Harr, S.D.2
Strickland, D.K.3
Hyman, B.T.4
-
20
-
-
0034721849
-
Apolipoprotein E receptors mediate the effects of β-amyloid on astrocyte cultures
-
LaDu, M. J., Shah, J. A., Reardon, C. A., Getz, G. S., Bu, G., Hu, J., Guo, L., and van Eldik, L. J. (2000) Apolipoprotein E receptors mediate the effects of β-amyloid on astrocyte cultures. J. Biol. Chem. 275, 33974-33980.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33974-33980
-
-
LaDu, M.J.1
Shah, J.A.2
Reardon, C.A.3
Getz, G.S.4
Bu, G.5
Hu, J.6
Guo, L.7
van Eldik, L.J.8
-
21
-
-
0031882562
-
β-Amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons
-
Beffert, U., Aumont, N., Dea, D., Lussier-Cacan, S., Davignon, J., and Poirier, J. (1998) β-Amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. J. Neurochem. 70, 1458-1466.
-
(1998)
J. Neurochem
, vol.70
, pp. 1458-1466
-
-
Beffert, U.1
Aumont, N.2
Dea, D.3
Lussier-Cacan, S.4
Davignon, J.5
Poirier, J.6
-
22
-
-
23944511140
-
Alzheimer's disease amyloid-β peptide modulates apolipoprotein E isoform specific receptor binding
-
Hone, E., Martins, I. J., Jeoung, M., Ji, T. H., Ganady, S. E., and Martins, R. N. (2005) Alzheimer's disease amyloid-β peptide modulates apolipoprotein E isoform specific receptor binding. J. Alzheimer's Dis. 7, 303-314.
-
(2005)
J. Alzheimer's Dis
, vol.7
, pp. 303-314
-
-
Hone, E.1
Martins, I.J.2
Jeoung, M.3
Ji, T.H.4
Ganady, S.E.5
Martins, R.N.6
-
23
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
24
-
-
0242662225
-
Intermolecular coiled-coil formation in human apolipoprotein E C-terminal domain
-
Choy, N., Raussens, V., and Narayanaswami, V. (2003) Intermolecular coiled-coil formation in human apolipoprotein E C-terminal domain. J. Mol. Biol. 334, 527-539.
-
(2003)
J. Mol. Biol
, vol.334
, pp. 527-539
-
-
Choy, N.1
Raussens, V.2
Narayanaswami, V.3
-
25
-
-
0035851137
-
Lipid association-induced N- and C-terminal domain reorganization in human apolipoprotein E3
-
Narayanaswami, V., Szeto, S. S., and Ryan, R. O. (2001) Lipid association-induced N- and C-terminal domain reorganization in human apolipoprotein E3. J. Biol. Chem. 276, 37853-37860.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 37853-37860
-
-
Narayanaswami, V.1
Szeto, S.S.2
Ryan, R.O.3
-
26
-
-
18844441394
-
Orientation and mode of lipid-binding interaction of human apolipoprotein E C-terminal domain
-
Raussens, V., Drury, J., Forte, T. M., Choy, N., Goormaghtigh, E., Ruysschaert, J. M., and Narayanaswami, V. (2005) Orientation and mode of lipid-binding interaction of human apolipoprotein E C-terminal domain. Biochem. J. 387, 747-754.
-
(2005)
Biochem. J
, vol.387
, pp. 747-754
-
-
Raussens, V.1
Drury, J.2
Forte, T.M.3
Choy, N.4
Goormaghtigh, E.5
Ruysschaert, J.M.6
Narayanaswami, V.7
-
27
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren, K. N., Manelli, A. M., Stine, W. B., Jr., Baker, L. K., Krafft, G. A., and LaDu, M. J. (2002) Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J. Biol. Chem. 277, 32046-32053.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
28
-
-
0030611858
-
Soluble amyloid Aβ-(1-40) exists as a stable dimer at low concentrations
-
Garzon-Rodriguez, W., Sepulveda-Becerra, M., Milton, S., and Glabe, C. G. (1997) Soluble amyloid Aβ-(1-40) exists as a stable dimer at low concentrations. J. Biol. Chem. 272, 21037-21044.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 21037-21044
-
-
Garzon-Rodriguez, W.1
Sepulveda-Becerra, M.2
Milton, S.3
Glabe, C.G.4
-
29
-
-
20544455385
-
Role of buried polar residues in helix bundle stability and lipid binding of apolipophorin III: Destabilization by threonine 31
-
Weers, P. M., Abdullahi, W. E., Cabrera, J. M., and Hsu, T. C. (2005) Role of buried polar residues in helix bundle stability and lipid binding of apolipophorin III: Destabilization by threonine 31. Biochemistry 44, 8810-8816.
-
(2005)
Biochemistry
, vol.44
, pp. 8810-8816
-
-
Weers, P.M.1
Abdullahi, W.E.2
Cabrera, J.M.3
Hsu, T.C.4
-
30
-
-
34447542267
-
Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediated functional impairment of human apolipoprotein E
-
Tamamizu-Kato, S., Wong, J. Y., Jairam, V., Uchida, K., Raussens, V., Kato, H., Ruyssachaert, J.-M., and Narayanaswami, V. (2007) Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediated functional impairment of human apolipoprotein E. Biochemistry 46, 8392-8400.
-
(2007)
Biochemistry
, vol.46
, pp. 8392-8400
-
-
Tamamizu-Kato, S.1
Wong, J.Y.2
Jairam, V.3
Uchida, K.4
Raussens, V.5
Kato, H.6
Ruyssachaert, J.-M.7
Narayanaswami, V.8
-
31
-
-
0027524130
-
Prevention of phospholipase-C induced aggregation of low density lipoprotein by amphipathic apolipoproteins
-
Liu, H., Scraba, D. G., and Ryan, R. O. (1993) Prevention of phospholipase-C induced aggregation of low density lipoprotein by amphipathic apolipoproteins. FEBS Lett. 316, 27-33.
-
(1993)
FEBS Lett
, vol.316
, pp. 27-33
-
-
Liu, H.1
Scraba, D.G.2
Ryan, R.O.3
-
32
-
-
0027186135
-
Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization
-
Westerlund, J. A., and Weisgraber, K. H. (1993) Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization. J. Biol. Chem. 268, 15745-15750.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 15745-15750
-
-
Westerlund, J.A.1
Weisgraber, K.H.2
-
33
-
-
0032951957
-
β-Amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: Relevance to Alzheimer's disease
-
Pillot, T., Goethals, M., Najib, J., Labeur, C., Lins, L., Chambaz, J., Brasseur, R., Vandekerckhove, J., and Rosseneu, M. (1999) β-Amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: Relevance to Alzheimer's disease. J. Neurochem. 72, 230-237.
-
(1999)
J. Neurochem
, vol.72
, pp. 230-237
-
-
Pillot, T.1
Goethals, M.2
Najib, J.3
Labeur, C.4
Lins, L.5
Chambaz, J.6
Brasseur, R.7
Vandekerckhove, J.8
Rosseneu, M.9
-
34
-
-
0033551431
-
Contribution of cysteine 158, the glycosylation site threonine 194, the amino- and carboxy-terminal domains of apolipoprotein E in the binding to amyloid peptide β (1-40)
-
Aleshkov, S. B., Li, X., Lavrentiadou, S. N., and Zannis, V. I. (1999) Contribution of cysteine 158, the glycosylation site threonine 194, the amino- and carboxy-terminal domains of apolipoprotein E in the binding to amyloid peptide β (1-40). Biochemistry 38, 8918-8925.
-
(1999)
Biochemistry
, vol.38
, pp. 8918-8925
-
-
Aleshkov, S.B.1
Li, X.2
Lavrentiadou, S.N.3
Zannis, V.I.4
-
35
-
-
0032802312
-
Molecular determinants of the interaction between the C-terminal domain of Alzheimer's β-amyloid peptide and apolipoprotein E α-helices
-
Lins, L., Thomas-Soumarmon, A., Pillot, T., Vandekerchkhove, J., Rosseneu, M., and Brasseur, R. (1999) Molecular determinants of the interaction between the C-terminal domain of Alzheimer's β-amyloid peptide and apolipoprotein E α-helices. J. Neurochem. 73, 758-769.
-
(1999)
J. Neurochem
, vol.73
, pp. 758-769
-
-
Lins, L.1
Thomas-Soumarmon, A.2
Pillot, T.3
Vandekerchkhove, J.4
Rosseneu, M.5
Brasseur, R.6
-
36
-
-
21844473805
-
Fluorescence resonance energy transfer analysis of apolipoprotein E C-terminal domain and amyloid β peptide (1-42) interaction
-
Phu, M. J., Hawbecker, S. K., and Narayanaswami, V. (2005) Fluorescence resonance energy transfer analysis of apolipoprotein E C-terminal domain and amyloid β peptide (1-42) interaction. J. Neurosci. Res. 80, 877-886.
-
(2005)
J. Neurosci. Res
, vol.80
, pp. 877-886
-
-
Phu, M.J.1
Hawbecker, S.K.2
Narayanaswami, V.3
-
37
-
-
0030786781
-
Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks
-
Phillips, J. C., Wriggers, W., Li, Z., Jonas, A., and Schulten, K. (1997) Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks. Biophys. J. 73, 2337-2346.
-
(1997)
Biophys. J
, vol.73
, pp. 2337-2346
-
-
Phillips, J.C.1
Wriggers, W.2
Li, Z.3
Jonas, A.4
Schulten, K.5
-
38
-
-
0034111173
-
Interaction of locust apolipophorin III with lipoproteins and phospholipid vesicles: Effect of glycosylation
-
Weers, P. M., van der Horst, D. J., and Ryan, R. O. (2000) Interaction of locust apolipophorin III with lipoproteins and phospholipid vesicles: Effect of glycosylation. J. Lipid Res. 41, 416-423.
-
(2000)
J. Lipid Res
, vol.41
, pp. 416-423
-
-
Weers, P.M.1
van der Horst, D.J.2
Ryan, R.O.3
-
39
-
-
0034721777
-
The lipid-associated conformation of the low density lipoprotein receptor binding domain of human apolipoprotein E
-
Fisher, C. A., Narayanaswami, V., and Ryan, R. O. (2000) The lipid-associated conformation of the low density lipoprotein receptor binding domain of human apolipoprotein E. J. Biol. Chem. 275, 33601-33606.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33601-33606
-
-
Fisher, C.A.1
Narayanaswami, V.2
Ryan, R.O.3
-
40
-
-
0034617305
-
Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid
-
Lu, B., Morrow, J. A., and Weisgraber, K. H. (2000) Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid. J. Biol. Chem. 275, 20775-20781.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 20775-20781
-
-
Lu, B.1
Morrow, J.A.2
Weisgraber, K.H.3
-
41
-
-
1842740161
-
Helix orientation of the functional domains in apolipoprotein E in discoidal high density lipoprotein particles
-
Narayanaswami, V., Maiorano, J. N., Dhanasekaran, P., Ryan, R. O., Phillips, M. C., Lund-Katz, S., and Davidson, W. S. (2004) Helix orientation of the functional domains in apolipoprotein E in discoidal high density lipoprotein particles. J. Biol. Chem. 279, 14273-14279.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 14273-14279
-
-
Narayanaswami, V.1
Maiorano, J.N.2
Dhanasekaran, P.3
Ryan, R.O.4
Phillips, M.C.5
Lund-Katz, S.6
Davidson, W.S.7
-
42
-
-
17644420761
-
Examination of lipid-bound conformation of apolipoprotein E4 by pyrene excimer fluorescence
-
Drury, J., and Narayanaswami, V. (2005) Examination of lipid-bound conformation of apolipoprotein E4 by pyrene excimer fluorescence. J. Biol. Chem. 280, 14605-14610.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 14605-14610
-
-
Drury, J.1
Narayanaswami, V.2
-
43
-
-
33947205478
-
The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins
-
Vedhachalam, C., Narayanaswami, V., Neto, N., Forte, T. M., Phillips, M. C., Lund-Katz, S., and Bielicki, J. K. (2007) The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins. Biochemistry 46, 2583-2593.
-
(2007)
Biochemistry
, vol.46
, pp. 2583-2593
-
-
Vedhachalam, C.1
Narayanaswami, V.2
Neto, N.3
Forte, T.M.4
Phillips, M.C.5
Lund-Katz, S.6
Bielicki, J.K.7
-
44
-
-
33746311471
-
Apolipoprotein E structure: Insights into function
-
Hatters, D. M., Peters-Libeu, C. A., and Weisgraber, K. H. (2006) Apolipoprotein E structure: Insights into function. Trends Biochem. Sci. 31, 445-454.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 445-454
-
-
Hatters, D.M.1
Peters-Libeu, C.A.2
Weisgraber, K.H.3
-
45
-
-
0033991858
-
Molecular basis of exchangeable apolipoprotein function
-
Narayanaswami, V., and Ryan, R. O. (2000) Molecular basis of exchangeable apolipoprotein function. Biochim. Biophys. Acta 1483, 15-36.
-
(2000)
Biochim. Biophys. Acta
, vol.1483
, pp. 15-36
-
-
Narayanaswami, V.1
Ryan, R.O.2
-
46
-
-
0035798681
-
Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles
-
Saito, H., Dhanasekaran, P., Baldwin, F., Weisgraber, K. H., Lund-Katz, S., and Phillips, M. C. (2001) Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles. J. Biol. Chem. 276, 40949-40954.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 40949-40954
-
-
Saito, H.1
Dhanasekaran, P.2
Baldwin, F.3
Weisgraber, K.H.4
Lund-Katz, S.5
Phillips, M.C.6
-
47
-
-
0030863380
-
Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: A possible role for apolipoprotein E in Alzheimer's disease
-
Aizawa, Y., Fukatsu, R., Takamaru, Y., Tsuzuki, K., Chiba, H., Kobayashi, K., Fujii, N., and Takahata, N. (1997) Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: A possible role for apolipoprotein E in Alzheimer's disease. Brain Res. 768, 208-214.
-
(1997)
Brain Res
, vol.768
, pp. 208-214
-
-
Aizawa, Y.1
Fukatsu, R.2
Takamaru, Y.3
Tsuzuki, K.4
Chiba, H.5
Kobayashi, K.6
Fujii, N.7
Takahata, N.8
-
48
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins
-
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U.S.A. 95, 6448-6453.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
49
-
-
0034609516
-
The oligomerization of amyloid β-protein begins intracellularly in cells derived from human brain
-
Walsh, D. M., Tseng, B. P., Rydel, R. E., Podlisny, M. B., and Selkoe, D. J. (2000) The oligomerization of amyloid β-protein begins intracellularly in cells derived from human brain. Biochemistry 39, 10831-10839.
-
(2000)
Biochemistry
, vol.39
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
50
-
-
9444245809
-
Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
Roher, A. E., Chaney, M. O., Kuo, Y. M., Webster, S. D., Stine, W. B., Haverkamp, L. J., Woods, A. S., Cotter, R. J., Tuohy, J. M., Krafft, G. A., Bonnell, B. S., and Emmerling, M. R. (1996) Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J. Biol. Chem. 271, 20631-20635.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
Kuo, Y.M.3
Webster, S.D.4
Stine, W.B.5
Haverkamp, L.J.6
Woods, A.S.7
Cotter, R.J.8
Tuohy, J.M.9
Krafft, G.A.10
Bonnell, B.S.11
Emmerling, M.R.12
-
51
-
-
16644379264
-
Natural oligomers of the amyloid-β protein specifically disrupt cognitive function
-
Cleary, J. P., Walsh, D. M., Hofmeister, J. J., Shankar, G. M., Kuskowski, M. A., Selkoe, D. J., and Ashe, K. H. (2005) Natural oligomers of the amyloid-β protein specifically disrupt cognitive function. Nat. Neurosci. 8, 79-84.
-
(2005)
Nat. Neurosci
, vol.8
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
Ashe, K.H.7
-
52
-
-
0029766916
-
Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
-
Dong, L. M., and Weisgraber, K. H. (1996) Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins. J. Biol. Chem. 271, 19053-19057.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 19053-19057
-
-
Dong, L.M.1
Weisgraber, K.H.2
-
53
-
-
22544443366
-
Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4
-
Hatters, D. M., Peters-Libeu, C. A., and Weisgraber, K. H. (2005) Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4. J. Biol. Chem. 280, 26477-26482.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 26477-26482
-
-
Hatters, D.M.1
Peters-Libeu, C.A.2
Weisgraber, K.H.3
-
54
-
-
0029989388
-
Apolipoprotein E produced by human monocyte-derived macrophages mediates cholesterol efflux that occurs in the absence of added cholesterol acceptors
-
Zhang, W. Y., Gaynor, P. M., and Kruth, H. S. (1996) Apolipoprotein E produced by human monocyte-derived macrophages mediates cholesterol efflux that occurs in the absence of added cholesterol acceptors. J. Biol. Chem. 271, 28641-28646.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 28641-28646
-
-
Zhang, W.Y.1
Gaynor, P.M.2
Kruth, H.S.3
-
55
-
-
0026742235
-
Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs
-
Herscovitz, H., Gantz, D., Tercyak, A. M., Zannis, V. I., and Small, D. M. (1992) Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs. J. Lipid Res. 33, 791-803.
-
(1992)
J. Lipid Res
, vol.33
, pp. 791-803
-
-
Herscovitz, H.1
Gantz, D.2
Tercyak, A.M.3
Zannis, V.I.4
Small, D.M.5
-
56
-
-
0026061357
-
The effect of apo E secretion on lipoprotein uptake in transfected cells
-
Shimano, H., Fukazawa, C., Shibasaki, Y., Mori, N., Gotoda, T., Harada, K., Shimada, M., Yamada, N., Yazaki, Y., and Takaku, F. (1991) The effect of apo E secretion on lipoprotein uptake in transfected cells. Biochim. Biophys. Acta 1086, 245-254.
-
(1991)
Biochim. Biophys. Acta
, vol.1086
, pp. 245-254
-
-
Shimano, H.1
Fukazawa, C.2
Shibasaki, Y.3
Mori, N.4
Gotoda, T.5
Harada, K.6
Shimada, M.7
Yamada, N.8
Yazaki, Y.9
Takaku, F.10
-
57
-
-
0032974482
-
Differential generation of high-density lipoprotein by endogenous and exogenous apolipoproteins in cultured fetal rat astrocytes
-
Ito, J., Zhang, L. Y., Asai, M., and Yokoyama, S. (1999) Differential generation of high-density lipoprotein by endogenous and exogenous apolipoproteins in cultured fetal rat astrocytes. J. Neurochem. 72, 2362-2369.
-
(1999)
J. Neurochem
, vol.72
, pp. 2362-2369
-
-
Ito, J.1
Zhang, L.Y.2
Asai, M.3
Yokoyama, S.4
-
58
-
-
0024399670
-
Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: Effect of cholesterol efflux
-
Dory, L. (1989) Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: Effect of cholesterol efflux. J. Lipid Res. 30, 809-816.
-
(1989)
J. Lipid Res
, vol.30
, pp. 809-816
-
-
Dory, L.1
-
59
-
-
0021337341
-
Synthesis, intracellular processing, and signal peptide of human apolipoprotein E
-
Zannis, V. I., McPherson, J., Goldberger, G., Karathanasis, S. K., and Breslow, J. L. (1984) Synthesis, intracellular processing, and signal peptide of human apolipoprotein E. J. Biol. Chem. 259, 5495-5499.
-
(1984)
J. Biol. Chem
, vol.259
, pp. 5495-5499
-
-
Zannis, V.I.1
McPherson, J.2
Goldberger, G.3
Karathanasis, S.K.4
Breslow, J.L.5
-
60
-
-
0033569749
-
Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice
-
Fagan, A. M., Holtzman, D. M., Munson, G., Mathur, T., Schneider, D., Chang, L. K., Getz, G. S., Reardon, C. A., Lukens, J., Shah, J. A., and LaDu, M. J. (1999) Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice. J. Biol. Chem. 274, 30001-30007.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 30001-30007
-
-
Fagan, A.M.1
Holtzman, D.M.2
Munson, G.3
Mathur, T.4
Schneider, D.5
Chang, L.K.6
Getz, G.S.7
Reardon, C.A.8
Lukens, J.9
Shah, J.A.10
LaDu, M.J.11
-
61
-
-
0035902514
-
Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
-
Huang, Y., Liu, X. Q., Wyss-Coray, T., Brecht, W. J., Sanan, D. A., and Mahley, R. W. (2001) Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc. Natl. Acad. Sci. U.S.A. 98, 8838-8843.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A
, vol.98
, pp. 8838-8843
-
-
Huang, Y.1
Liu, X.Q.2
Wyss-Coray, T.3
Brecht, W.J.4
Sanan, D.A.5
Mahley, R.W.6
-
62
-
-
0035061891
-
Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Aβ aggregation
-
Cho, H. S., Hyman, B. T., Greenberg, S. M., and Rebeck, G. W. (2001) Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Aβ aggregation. J. Neuropathol. Exp. Neurol. 60, 342-349.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, pp. 342-349
-
-
Cho, H.S.1
Hyman, B.T.2
Greenberg, S.M.3
Rebeck, G.W.4
-
63
-
-
0029832616
-
A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity
-
Marques, M. A., Tolar, M., Harmony, J. A., and Crutcher, K. A. (1996) A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity. NeuroReport 7, 2529-2532.
-
(1996)
NeuroReport
, vol.7
, pp. 2529-2532
-
-
Marques, M.A.1
Tolar, M.2
Harmony, J.A.3
Crutcher, K.A.4
-
64
-
-
0030804828
-
Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated
-
Tolar, M., Marques, M. A., Harmony, J. A., and Crutcher, K. A. (1997) Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated. J. Neurosci. 17, 5678-5686.
-
(1997)
J. Neurosci
, vol.17
, pp. 5678-5686
-
-
Tolar, M.1
Marques, M.A.2
Harmony, J.A.3
Crutcher, K.A.4
-
65
-
-
24144466495
-
A 13 kDa carboxy-terminal fragment of ApoE stabilizes Aβ hexamers
-
Wellnitz, S., Friedlein, A., Bonanni, C., Anquez, V., Goepfert, F., Loetscher, H., Adessi, C., and Czech, C. (2005) A 13 kDa carboxy-terminal fragment of ApoE stabilizes Aβ hexamers. J. Neurochem. 94, 1351-1360.
-
(2005)
J. Neurochem
, vol.94
, pp. 1351-1360
-
-
Wellnitz, S.1
Friedlein, A.2
Bonanni, C.3
Anquez, V.4
Goepfert, F.5
Loetscher, H.6
Adessi, C.7
Czech, C.8
-
66
-
-
0029866177
-
The interaction between apolipoprotein E and Alzheimer's amyloid β-peptide is dependent on β-peptide conformation
-
Golabek, A. A., Soto, C., Vogel, T., and Wisniewski, T. (1996) The interaction between apolipoprotein E and Alzheimer's amyloid β-peptide is dependent on β-peptide conformation. J. Biol. Chem. 271, 10602-10606.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 10602-10606
-
-
Golabek, A.A.1
Soto, C.2
Vogel, T.3
Wisniewski, T.4
-
67
-
-
0033869207
-
Sodium dodecyl sulfate-resistant complexes of Alzheimer's amyloid β-peptide with the N-terminal, receptor binding domain of apolipoprotein E
-
Golabek, A. A., Kida, E., Walus, M., Perez, C., Wisniewski, T., and Soto, C. (2000) Sodium dodecyl sulfate-resistant complexes of Alzheimer's amyloid β-peptide with the N-terminal, receptor binding domain of apolipoprotein E. Biophys. J. 79, 1008-1015.
-
(2000)
Biophys. J
, vol.79
, pp. 1008-1015
-
-
Golabek, A.A.1
Kida, E.2
Walus, M.3
Perez, C.4
Wisniewski, T.5
Soto, C.6
|