Murine osteoblasts regulate mesenchymal stem cells via WNT and cadherin pathways: Mechanism depends on cell-cell contact mode

Journal of Tissue Engineering and Regenerative Medicine

Volumn 1, Issue 1, 2007, Pages 39-50

  Wang, Yongzhong ^a   Volloch, Vladimir ^a   Pindrus, Mariya A ^a   Blasioli, Dominick J ^a   Chen, Jingsong ^a   Kaplan, David L ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Cadherin; Mesenchymal stem cell; Osteoblast; WNT; Catenin

Indexed keywords

BONE; FLOWCHARTING; GLYCOPROTEINS; OSTEOBLASTS; PROTEINS; STEM CELLS;

CADHERIN; CELL TYPES; CELL-CELL CONTACT; CONTACT MODES; MESENCHYMAL STEM CELL; PROTEIN LEVEL; STIMULATORY EFFECTS; WNT; WNT PATHWAY; Β-CATENIN;

CELL CULTURE;

CADHERIN; WNT PROTEIN;

ANIMAL; ARTICLE; BONE DEVELOPMENT; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; COCULTURE; CYTOLOGY; MESENCHYMAL STEM CELL; METABOLISM; MOUSE; OSTEOBLAST; SIGNAL TRANSDUCTION;

ANIMALS; CADHERINS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; COCULTURE TECHNIQUES; MESENCHYMAL STEM CELLS; MICE; OSTEOBLASTS; OSTEOGENESIS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 42949140534     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.6     Document Type: Article

References (41)

1. Anjos-Afonso F, Siapati EK, Bonnet D. 2004; In vivo contribution of murine mesenchymal stem cells into multiple cell types under minimal damage conditions. J Cell Sci 117: 5655-5664.
2. Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA. 2001; Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 3: 683-686.
3. BennettCN, LongoKA, WrightWS, et al. 2005; Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci USA 102: 3324-3329.
4. Calvi LM, Adams GB, Weibrecht KW, et al. 2003; Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425: 841-846.
5. Cheng SL, Lecanda F, Davidson MK, et al. 1998; Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation. J BoneMiner Res 13: 633-644.
6. Church V, Nohno T, Linker C, Marcelle C, Francis-West P. 2002; Wnt regulation of chondrocyte differentiation. J Cell Sci 115: 4809-4818.
7. Day TF, Guo X, Garrett-Beal L, Yang Y. 2005; Wnt/β-catenin signalling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 8: 739-750.
8. Fridenshtein A. 1982; [Stromal bone marrow cells and the haematopoietic microenvironment]. Arkh Patol 44: 3-11.
9. Gerstenfeld LC, Barnes GL, Shea CM, Einhorn TA. 2003; Osteogenic differentiation is selectively promoted by morphogenetic signals from chondrocytes and synergized by a nutrient rich growth environment. Connect Tissue Res 44(SUPPL 1): 85-91.
10. Gerstenfeld LC, Cruceta J, Shea CM, et al. 2002; Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells. J Bone Miner Res 17: 221-230.
11. Glass DA II, Bialek P, Ahn JD, et al. 2005; Canonical Wnt signalling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 8: 751-764.
12. Glinka A, Wu W, Delius H, et al. 1998; Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391: 357-362.
13. Haegel H, Larue L, Ohsugi M, et al. 1995; Lack of β-catenin affects mouse development at gastrulation. Development 121: 3529-3537.
14. Hartmann C, Tabin CJ. 2000; Dual roles of Wnt signalling during chondrogenesis in the chicken limb. Development 127: 3141-3159.
15. Hartmann C, Tabin CJ. 2001; Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 104: 341-351.
16. Heino TJ, Hentunen TA, Vaananen HK. 2004; Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Exp Cell Res 294: 458-468.
17. Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C. 2005; Canonical Wnt/β-catenin signalling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 8: 727-738.
18. Hoang BH, Kubo T, Healey JH, et al. 2004; Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma. Int J Cancer 109: 106-111.
19. Hu H, Hilton MJ, Tu X, et al. 2005; Sequential roles of Hedgehog and Wnt signalling in osteoblast development. Development 132: 49-60.
20. Huelsken J, Vogel R, Brinkmann V, et al. 2000; Requirement for β-catenin in anterior-posterior axis formation in mice. J Cell Biol 148: 567-578.
21. Hughes FJ, McCulloch CA. 1991; Stimulation of the differentiation of osteogenic rat bone marrow stromal cells by osteoblast cultures. Lab Invest J Tech Methods Pathol 64: 617-622.
22. Kii I, Amizuka N, Shimomura J, Saga Y, Kudo A. 2004; Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteolineage and the chondro-lineage. J BoneMinerRes 19: 1840-1849
23. Kim H, Lee JH, Suh H. 2003; Interaction of mesenchymal stem cells and osteoblasts for in vitro osteogenesis. Yonsei Med J 44: 187-197.
24. Logan CY, Nusse R. 2004; The Wnt signalling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781-810.
25. Mao B,Wu W, Davidson G, et al. 2002; Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling. Nature 417: 664-667.
26. Mao B, Wu W, Li Y, et al. 2001; LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411: 321-325.
27. Nelson WJ, Nusse R. 2004; Convergence of Wnt, β-catenin, and cadherin pathways. Science 303: 1483-1487.
28. Nusse R. 2001; Developmental biology. Making head or tail of Dickkopf. Nature 411: 255-256.
29. Ott SM. 2002; Histomorphometric analysis of bone remodelling. In Principles of Bone Biology, 2nd edn, Bilezikian JP, Raisz LG, Rodan GA (eds). Academic Press: New York; 303-319.
30. Phinney DG, Kopen G, Isaacson RL, Prockop DJ. 1999; Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. J Cell Biochem 72: 570-585.
31. Potter E, Bergwitz C, Brabant G. 1999; The cadherin-catenin system: implications for growth and differentiation of endocrine tissues. Endocr Rev 20: 207-239.
32. Schreiber E, Matthias P, Muller MM, Schaffner W. 1989; Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 17: 6419.
33. Semenov MV, Tamai K, Brott BK, et al. 2001; Head inducer Dickkopf-1 is a ligand for Wnt co-receptor LRP6. Curr Biol 11: 951-961.
34. Topol L, Jiang X, Choi H, et al. 2003; Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent β-catenin degradation. J Cell Biol 162: 899-908.
35. Tropel P, Noel D, Platet N, et al. 2004; Isolation and characterization of mesenchymal stem cells from adult mouse bone marrow. Exp Cell Res 295: 395-406.
36. Wang D, Christensen K, Chawla K, et al. 1999; Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res 14: 893-903.
37. Watt FM, Hogan BL. 2000; Out of Eden: stem cells and their niches. Science 287: 1427-1430.
38. Westendorf JJ, Kahler RA, Schroeder TM. 2004; Wnt signalling in osteoblasts and bone diseases. Gene 341: 19-39.
39. Yang Y, Topol L, Lee H, Wu J. 2003; Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Development 130: 1003-1015.
40. Zhang J, Niu C, Ye L, et al. 2003; Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425: 836-841.
41. Zhang Y,Wang Y, Li X, et al. 2004; The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol 24: 4677-4684.