메뉴 건너뛰기




Volumn 143, Issue 6, 2007, Pages 505-512

Macrophage, inflammation, adipose tissue, obesity and insulin resistance;Macrófagos, inflamación, tejido adiposo, obesidad y resistencia a la insulina

Author keywords

Adipocite; Endothelial dysfunction; Inflammation; Insulin resistance; Macrophage; MCP1

Indexed keywords

CHEMOKINE RECEPTOR CCR2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; CCL2 PROTEIN, HUMAN; CCR2 PROTEIN, HUMAN;

EID: 42949138485     PISSN: 00163813     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (25)

References (54)
  • 1
    • 33644898538 scopus 로고    scopus 로고
    • Metabolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds
    • Grundy SM. Metabolic syndrome: connecting and reconciling cardiovascular and diabetes worlds. J Am Coll Cardiol 2006;47:1093-100.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1093-1100
    • Grundy, S.M.1
  • 2
    • 27644463193 scopus 로고    scopus 로고
    • American Heart Association; National Heart, Lung, and Blood Institute; Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, et al. Diagnosis and management of the metabolic syndrome. An American Heart Association/ National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2005;13:322-327.
    • American Heart Association; National Heart, Lung, and Blood Institute; Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, et al. Diagnosis and management of the metabolic syndrome. An American Heart Association/ National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2005;13:322-327.
  • 3
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 4
    • 32144448122 scopus 로고    scopus 로고
    • A constellation of complications: The metabolic syndrome
    • Grundy SM. A constellation of complications: the metabolic syndrome. Clin Cornerstone 2005;7:36-45.
    • (2005) Clin Cornerstone , vol.7 , pp. 36-45
    • Grundy, S.M.1
  • 5
    • 0026468362 scopus 로고
    • What if Minkowski had been ageusic? An alternative angle on diabetes
    • McGarry JD. What if Minkowski had been ageusic? An alternative angle on diabetes. Science 1992;258:766-770.
    • (1992) Science , vol.258 , pp. 766-770
    • McGarry, J.D.1
  • 6
    • 0028839110 scopus 로고
    • Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans
    • Lewis GF, Uffelman KD, Szeto LW, Weller B, Steiner G. Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans. J Clin Invest 1995;95:158-166.
    • (1995) J Clin Invest , vol.95 , pp. 158-166
    • Lewis, G.F.1    Uffelman, K.D.2    Szeto, L.W.3    Weller, B.4    Steiner, G.5
  • 7
    • 0024500560 scopus 로고
    • Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases
    • Eckel RH. Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N Engl J Med 1989;320:1060-1068.
    • (1989) N Engl J Med , vol.320 , pp. 1060-1068
    • Eckel, R.H.1
  • 8
    • 0037031893 scopus 로고    scopus 로고
    • Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3
    • Kim YB, Shulman GI, Kahn BB. Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3. J Biol Chem 2002;277:32915-32922.
    • (2002) J Biol Chem , vol.277 , pp. 32915-32922
    • Kim, Y.B.1    Shulman, G.I.2    Kahn, B.B.3
  • 9
    • 0346250164 scopus 로고    scopus 로고
    • Role of Ser/Thr kinases in the uncoupling of insulin signaling
    • Zick Y. Role of Ser/Thr kinases in the uncoupling of insulin signaling. Int J Obes Relat Metab Disord 2003;27(Suppl 3):S56-S60.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.SUPPL. 3
    • Zick, Y.1
  • 10
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 12
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000;275:9047-9054.
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 14
    • 0037184925 scopus 로고    scopus 로고
    • Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
    • Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 2002;277:50230-50236.
    • (2002) J Biol Chem , vol.277 , pp. 50230-50236
    • Yu, C.1    Chen, Y.2    Cline, G.W.3    Zhang, D.4    Zong, H.5    Wang, Y.6
  • 15
    • 0036295566 scopus 로고    scopus 로고
    • Protein kinase C and lipid-induced insulin resistance in skeletal muscle
    • Schmitz-Peiffer C. Protein kinase C and lipid-induced insulin resistance in skeletal muscle. Ann N Y Acad Sci 2002;967:146-157.
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 146-157
    • Schmitz-Peiffer, C.1
  • 16
    • 0037073679 scopus 로고    scopus 로고
    • Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex
    • Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ, et al. Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex. J Biol Chem 2002;277:48115-48121.
    • (2002) J Biol Chem , vol.277 , pp. 48115-48121
    • Gao, Z.1    Hwang, D.2    Bataille, F.3    Lefevre, M.4    York, D.5    Quon, M.J.6
  • 17
    • 0346880505 scopus 로고    scopus 로고
    • Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance
    • Shoelson SE, Lee J, Yuan M. Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance. Int J Obes Relat Metab Disord 2003;27(Suppl 3):S49-S52.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.SUPPL. 3
    • Shoelson, S.E.1    Lee, J.2    Yuan, M.3
  • 18
    • 0042330251 scopus 로고    scopus 로고
    • Minireview. The adipocyte: At the crossroads of energy homeostasis, inflammation, and atherosclerosis
    • Rajala MW, Scherer PE. Minireview. The adipocyte: at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 2003;144:3765-3773.
    • (2003) Endocrinology , vol.144 , pp. 3765-3773
    • Rajala, M.W.1    Scherer, P.E.2
  • 19
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation stress, and diabetes
    • Wellen KE, Hotamisligil GS. Inflammation stress, and diabetes. J Clin Invest 2005;115:1111-1119.
    • (2005) J Clin Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 20
    • 0034029201 scopus 로고    scopus 로고
    • Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture
    • Bornstein SR, Abu-Asab M, Glasow A, Path G, Hauner H, Tsokos M, et al. Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. Diabetes 2000;49:532-538.
    • (2000) Diabetes , vol.49 , pp. 532-538
    • Bornstein, S.R.1    Abu-Asab, M.2    Glasow, A.3    Path, G.4    Hauner, H.5    Tsokos, M.6
  • 21
    • 2342537773 scopus 로고    scopus 로고
    • From blood monocytes to adipose tissue-resident macrophages: Induction of diapedesis by human mature adipocytes
    • Curat CA, Miranville A, Sengenes C, Diehl M, Tonus C, Busse R, et al. From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes 2004;53:1285-1292.
    • (2004) Diabetes , vol.53 , pp. 1285-1292
    • Curat, C.A.1    Miranville, A.2    Sengenes, C.3    Diehl, M.4    Tonus, C.5    Busse, R.6
  • 22
    • 0033002831 scopus 로고    scopus 로고
    • Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas
    • Vacca A, Ribatti D, Ruco L, Giacchetta F, Nico B, Quondamatteo F, et al. Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. Br J Cancer 1999;79:965-970.
    • (1999) Br J Cancer , vol.79 , pp. 965-970
    • Vacca, A.1    Ribatti, D.2    Ruco, L.3    Giacchetta, F.4    Nico, B.5    Quondamatteo, F.6
  • 23
    • 0036995812 scopus 로고    scopus 로고
    • Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals
    • Takahashi K, Takeya M, Sakashita N. Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals. Med Electron Microsc 2002;35:179-203.
    • (2002) Med Electron Microsc , vol.35 , pp. 179-203
    • Takahashi, K.1    Takeya, M.2    Sakashita, N.3
  • 25
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003;112:1821-1830.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 26
    • 0032753226 scopus 로고    scopus 로고
    • Early upregulation of endothelial adhesion molecules in obese hypertensive men
    • Ferri C, Desideri G, Valenti M, Bellini C, Pasin M, Santucci A, et al. Early upregulation of endothelial adhesion molecules in obese hypertensive men. Hypertension 1999;34:568-573.
    • (1999) Hypertension , vol.34 , pp. 568-573
    • Ferri, C.1    Desideri, G.2    Valenti, M.3    Bellini, C.4    Pasin, M.5    Santucci, A.6
  • 27
    • 0035552478 scopus 로고    scopus 로고
    • Increasing plasma levels of soluble cell adhesion molecules (sE-Selectin, sP-Selectin and sICAM-1) in overweight adults with combined hyperlipidemia
    • Kvasnicka T, Kvasnicka J, Ceska R, Grauova B, Vrablik M. Increasing plasma levels of soluble cell adhesion molecules (sE-Selectin, sP-Selectin and sICAM-1) in overweight adults with combined hyperlipidemia. Sb Lek 2001;102:473-477.
    • (2001) Sb Lek , vol.102 , pp. 473-477
    • Kvasnicka, T.1    Kvasnicka, J.2    Ceska, R.3    Grauova, B.4    Vrablik, M.5
  • 29
    • 0348048487 scopus 로고    scopus 로고
    • Higher production of interleukin-8 in visceral compared to subcutaneous adipose tissue: Implications of non-adipose cells in adipose tissue
    • Bruun JM, Lihn AS, Madan AK, Pedersen SB, Schiott KM, Fain JN, et al. Higher production of interleukin-8 in visceral compared to subcutaneous adipose tissue: implications of non-adipose cells in adipose tissue. Am J Physiol Endocrinol Metab 2004;286:E8-E13.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Bruun, J.M.1    Lihn, A.S.2    Madan, A.K.3    Pedersen, S.B.4    Schiott, K.M.5    Fain, J.N.6
  • 30
    • 0032999682 scopus 로고    scopus 로고
    • Leptin induces oxidative stress in human endothelial cells
    • Bouloumie A, Marumo T, Lafontan M, Busse R. Leptin induces oxidative stress in human endothelial cells. FASEB J 1999;13:1231-1238.
    • (1999) FASEB J , vol.13 , pp. 1231-1238
    • Bouloumie, A.1    Marumo, T.2    Lafontan, M.3    Busse, R.4
  • 31
    • 0035816639 scopus 로고    scopus 로고
    • Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
    • Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzmán M, Brownlee M. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem 2001;276:25096-25100.
    • (2001) J Biol Chem , vol.276 , pp. 25096-25100
    • Yamagishi, S.I.1    Edelstein, D.2    Du, X.L.3    Kaneda, Y.4    Guzmán, M.5    Brownlee, M.6
  • 32
    • 0344443732 scopus 로고    scopus 로고
    • Adiposity elevates plasma MCP-1 levels leading to the increased CD11bpositive monocytes in mice
    • Takahashi K, Mizuarai S, Araki H, Mashiko S, Ishihara A, Kanatani A, et al. Adiposity elevates plasma MCP-1 levels leading to the increased CD11bpositive monocytes in mice. J Biol Chem 2003;278:46654-46660.
    • (2003) J Biol Chem , vol.278 , pp. 46654-46660
    • Takahashi, K.1    Mizuarai, S.2    Araki, H.3    Mashiko, S.4    Ishihara, A.5    Kanatani, A.6
  • 34
    • 17844393870 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): Implication of macrophages resident in the AT
    • Bruun JM, Lihn AS, Pedersen SB, Richelsen B. Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT. J Clin Endocrinol Metab 2005;90:2282-2289.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2282-2289
    • Bruun, J.M.1    Lihn, A.S.2    Pedersen, S.B.3    Richelsen, B.4
  • 35
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci USA 2003;100:7265-7270.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7265-7270
    • Sartipy, P.1    Loskutoff, D.J.2
  • 36
    • 0030003249 scopus 로고    scopus 로고
    • Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC
    • Kurihara T, Bravo R. Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC. J Biol Chem 1996;271:11603-11607.
    • (1996) J Biol Chem , vol.271 , pp. 11603-11607
    • Kurihara, T.1    Bravo, R.2
  • 37
    • 0242273333 scopus 로고    scopus 로고
    • Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization
    • Charo IF, Peters W. Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization. Microcirculation 2003;10:259-264.
    • (2003) Microcirculation , vol.10 , pp. 259-264
    • Charo, I.F.1    Peters, W.2
  • 38
    • 0037137305 scopus 로고    scopus 로고
    • Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice
    • Inoue S, Egashira K, Ni W, Kitamoto S, Usui M, Otani K, et al. Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice. Circulation 2002;106:2700-2706.
    • (2002) Circulation , vol.106 , pp. 2700-2706
    • Inoue, S.1    Egashira, K.2    Ni, W.3    Kitamoto, S.4    Usui, M.5    Otani, K.6
  • 39
    • 0038705876 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 induces scavenger receptor expression and monocyte differentiation into foam cells
    • Tabata T, Mine S, Kawahara C, Okada Y, Tanaka Y. Monocyte chemoattractant protein-1 induces scavenger receptor expression and monocyte differentiation into foam cells. Biochem Biophys Res Commun 2003;305:380-385.
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 380-385
    • Tabata, T.1    Mine, S.2    Kawahara, C.3    Okada, Y.4    Tanaka, Y.5
  • 42
  • 43
    • 26844448558 scopus 로고    scopus 로고
    • Discovery and pharmacological characterization of a novel rodent active CCR2 antagonist, INCB3344
    • Brodmerkel CM. Discovery and pharmacological characterization of a novel rodent active CCR2 antagonist, INCB3344. J Immunol 2005;175:5370-5378.
    • (2005) J Immunol , vol.175 , pp. 5370-5378
    • Brodmerkel, C.M.1
  • 44
    • 0015473277 scopus 로고
    • Cellularity of adipose depots in six strains of genetically obese mice
    • Johnson PR, Hirsch J. Cellularity of adipose depots in six strains of genetically obese mice. J Lipid Res 1972;13:2-11.
    • (1972) J Lipid Res , vol.13 , pp. 2-11
    • Johnson, P.R.1    Hirsch, J.2
  • 45
    • 0021014504 scopus 로고
    • Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution
    • Krotkiewski M, Bjorntorp P, Sjöstrom L, Smith U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J Clin Invest 1983;72:1150-1162.
    • (1983) J Clin Invest , vol.72 , pp. 1150-1162
    • Krotkiewski, M.1    Bjorntorp, P.2    Sjöstrom, L.3    Smith, U.4
  • 46
    • 0026730037 scopus 로고
    • Role of body fat distribution in the decline in insulin sensitivity and glucose tolerance with age
    • Coon PJ, Rogus EM, Drinkwater D, Muller DC, Goldberg AP. Role of body fat distribution in the decline in insulin sensitivity and glucose tolerance with age. J Clin Endocrinol Metab 1992;75:1125-1132.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1125-1132
    • Coon, P.J.1    Rogus, E.M.2    Drinkwater, D.3    Muller, D.C.4    Goldberg, A.P.5
  • 49
    • 0031158830 scopus 로고    scopus 로고
    • A review of the microcirculation of adipose tissue: Anatomic, metabolic, and angiogenic perspectives
    • Crandall DL, Hausman GJ, Kral JG. A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives. Microcirculation 1997;4:211-232.
    • (1997) Microcirculation , vol.4 , pp. 211-232
    • Crandall, D.L.1    Hausman, G.J.2    Kral, J.G.3
  • 50
    • 0036035527 scopus 로고    scopus 로고
    • Inflammatory bio-markers and cardiovascular risk prediction
    • Blake GJ, Ridker PM. Inflammatory bio-markers and cardiovascular risk prediction. J Intern Med 2002;252:283-294.
    • (2002) J Intern Med , vol.252 , pp. 283-294
    • Blake, G.J.1    Ridker, P.M.2
  • 51
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKKβ and NF-êB
    • Cai D. Local and systemic insulin resistance resulting from hepatic activation of IKKβ and NF-êB. Nat Med 2005;11:183-190.
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1
  • 52
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005;46:2347-2355.
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3    Murano, I.4    Ceresi, E.5    Faloia, E.6
  • 53
    • 33846410348 scopus 로고    scopus 로고
    • Macrophage-secreted factors impair human adipogenesis: Involvement of proinflammatory state in preadipocytes
    • Lacasa D, Taleb S, Keophiphath M, Miranville A, Clement K. Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes. Endocrinology 2007;148:868-877.
    • (2007) Endocrinology , vol.148 , pp. 868-877
    • Lacasa, D.1    Taleb, S.2    Keophiphath, M.3    Miranville, A.4    Clement, K.5
  • 54
    • 34247570643 scopus 로고    scopus 로고
    • Abdominal obesity and cardiovascular disease risk: The emerging role of the adipocyte
    • Lee Y, Pratley RE. Abdominal obesity and cardiovascular disease risk: the emerging role of the adipocyte. JCRP 2007;27:2-10.
    • (2007) JCRP , vol.27 , pp. 2-10
    • Lee, Y.1    Pratley, R.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.