Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 8, 2008, Pages 2987-2992

  Tsatsanis, Christos ^a   Vaporidi, Katerina ^b   Zacharioudaki, Vassiliki ^a   Androulidaki, Ariadne ^a   Sykulev, Yuri ^c   Margioris, Andrew N ^a   Tsichlis, Philip N ^b  

^a UNIVERSITY OF CRETE   (Greece)

^b TUFTS MEDICAL CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cancer; CD8; CTLA4; Lymphoma; T cell receptor transgene 2C (TCR2C)

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MITOGEN ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; MAP3K8 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; ONCOPROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POPULATION; CELL PROLIFERATION; CELL STIMULATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE FUNCTION; GENETIC CROSS; LATENT PERIOD; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; T CELL LYMPHOMA; THYMUS; TPL2 GENE; TRANSGENE; TUMOR CELL; TUMOR SUPPRESSOR GENE; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; FLOW CYTOMETRY; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSGENES;

EID: 42949137559     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0708381104     Document Type: Article

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