Humic substances - Part 2: Interactions with organisms

Environmental Science and Pollution Research

Volumn 15, Issue 2, 2008, Pages 128-135

  Steinberg, Christian E W ^a,f   Meinelt, Thomas ^b   Timofeyev, Maxim A ^c,d   Bittner, Michal ^e   Menzel, Ralph ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b LEIBNIZ INSTITUTE OF FRESHWATER ECOLOGY AND INLAND FISHERIES   (Germany)

^c IRKUTSK STATE UNIVERSITY   (Russian Federation)

^d Baikalean Research Centre   (Russian Federation)

^e MASARYK UNIVERSITY   (Czech Republic)

^f Arboretum   (Germany)

Author keywords

Chemical stress defense; Dissolved humic substances; Feminization; Longevity; Membrane irritation; Multiple stress resistance; Natural herbicides; Natural organic matter (NOM); Teratogenic effects

Indexed keywords

ALGA; CYPRINID; DEFENSE MECHANISM; DISSOLVED MATTER; ENVIRONMENTAL STRESS; EXPERIMENTAL STUDY; HERBICIDE; HUMIC SUBSTANCE; MACROPHYTE; METABOLISM; NEMATODE; PHYSIOLOGICAL RESPONSE; SEX REVERSAL;

ALGAE; AMPHIBIA; CAENORHABDITIS ELEGANS; CYANOBACTERIA; DANIO RERIO; EUKARYOTA;

ENDOCRINE DISRUPTOR; FRESH WATER; GLYCOPROTEIN P; HEAT SHOCK PROTEIN; OXYGEN; PHEROMONE; SODIUM;

ALGA; ANIMAL; CELL MEMBRANE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMIC SUBSTANCE; METABOLISM; PHOTOSYNTHESIS; PLANT; REVIEW; WATER POLLUTANT;

ALGAE; ANIMALS; CELL MEMBRANE; ENDOCRINE DISRUPTORS; FRESH WATER; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMIC SUBSTANCES; OXYGEN; P-GLYCOPROTEINS; PHEROMONES; PHOTOSYNTHESIS; PLANTS; SODIUM; WATER POLLUTANTS;

EID: 42949137152     PISSN: 09441344     EISSN: None     Source Type: Journal    
DOI: 10.1065/espr2007.07.434     Document Type: Review

References (94)

1. Beer AM, Lukanov J, Sagorchev P (2000): The influence of fulvic and ulmic acids from peat, on the spontaneous contractile activity of smooth muscles. Phytomedicine 7, 407-415
2. Beer AM, Sagrochev P, Lukanov J (2002): Isolation of biologically active fractions from the water soluble components of fulvic and ulmic acids from peat. Phytomedicine 9, 659-666
3. Beer AM, Junginger HE, Lukanov J, Sagorchev P (2003): Evaluation of the permeation of peat substances through human skin in vitro. Intern J Pharmacol 253, 169-175
4. Bertolo A, Magnan P (2007): Logging-induced variations in dissolved organic carbon affect yellow perch (Perca flavescens) recruitment in Canadian Shield lakes. Can J Fish Aquat Sci 64, 181-186
5. Bierkens J, Van de Perre W, Maes J (1998): Effect of different environmental variables on the synthesis of Hsp 70 in Raphidocelis subcapitata. Comp Biochem Physiol A 120, 29-34
6. Bijlsma R, Loeschke V (eds) (1997): Environmental Stress, Adaptation and Evolution. Birkhäuser, Basel
7. Bittner M, Hilscherová K, Giesy J (2007): Changes of AhR-mediated activity of humic substances after irradiation. Environ Intern 3, 812-816
8. Bittner M, Janošek J, Hilscherová K, Giesy J, Holoubek I, Bláha L (2006): Activation of Ah receptor by pure humic acids. Environ Toxicol 21, 338-342
9. Blokhina O, Violainen E, Fagerstedt KV (2003): Antioxidants, oxidative damage and oxygen deprivation stress: a review. Ann Bot 91, 179-194
10. Calabrese EJ (2005): Paradigm lost, paradigm found: The re-emergence of hormesis as a fundamental dose response model in toxicological sciences. Environ Poll 138, 379-412
11. Cazenave J, Ángeles Bistoni M de, Zwirnmann E, Wunderlin DA, Wiegand C (2006): Attenuating effects of natural organic matter on microcystin toxicity in zebra fish (Danio rerio) embryos - Benefits and costs of microcystin detoxication. Environ Toxicol 21, 22-32
12. Chao NL (2001): The fishery, diversity, and conservation of ornamental fishes in the Rio Negro Basin, Brazil: A review of Project Piaba (1989-99). In: Chao NL, Petry P, Prang G, Sonneschien L, Tlusty M (eds), Conservation and Management of Ornamental Fish Resources of the Rio Negro Basin, Amazonia, Brazil - Project Piaba, Universidade do Amazonas, Manaus, pp 161-204
13. Cheng ML, Ho HY, Chiu DTY, Lu FJ (1999): Humic acid-mediated oxidative damages to human erythrocytes: A possible mechanism leading to anemia in Blackfoot disease. Free Rad Biol Med 27, 470-477
14. Cheng ML, Ho HY, Huang YW, Lu FJ, Chiu DTY (2003): Humic acid induces oxidative DNA damage, growth retardation, and apoptosis in human primary fibroblasts. Exper Biol Med 228, 413-423
15. El-Shall SA, Eissa FM, Fathi MA, Walia D, Kotob SI (2007): The role of rootstocks and Actosol® humic acid in enhancing the salt tolerance of some deciduous fruit seedlings. Lecture at Humic Science & Technology Ten: Structures, Properties and Uses. Northeastern University, Boston, MA, March 21-23, 2007
16. Farjalla VF, Amado AM, Suhett AL (2008): Humic Substances. Part 3: Reviewing DOC removal paradigms in highly humic aquatic ecostems. Env Sci Pollt Res (in press)
17. Gau RJ, Yang HL, Chow SN, Suen JL, Lu FJ (2000): Humic acid suppresses the LPS-induced expression of cell-surface adhesion proteins through the inhibition of NF-κB activation. Toxicol Appl Pharmacol 166, 59-67
18. Gau RJ, Yang HL, Suen JL, Lu FJ (2001): Induction of oxidative stress by humic acid through increasing intracellular iron: A possible mechanism leading to atherothrombotic vascular disorder in blackfoot disease. Biochem Biophys Res Comm 283, 743-749
19. Geller A (1985): Light-induced conversion of refractory, high molecular weight lake water constituents. Schweiz Z Hydrol 47, 21-26
20. Gems D, McElwee JJ (2003): Microarraying mortality. Nature 424, 259-261
21. Glover CN, Pane EF, Wood CM (2005): Humic substances influence sodium metabolism in the freshwater crustacean Daphnia magna. Physiol Biochem Zool 78, 405-416
22. Glover CN, Wood CM (2005): The disruption of Daphnia magna sodium metabolism by humic substances: Mechanism of action and effect of humic substance source. Physiol Biochem Zool 78, 1005-1016
23. Gonçalves JF Jr, Santos AM, Esteves FA (2004): The influence of the chemical composition of Typha domingensis and Nymphaea ampla on invertebrate colonization during decomposition in a Brazilian coastal lagoon. Hydrobiologia 527, 125-137
24. Gryndler M, Hršelová H, Sudová R, Gryndlerová, Řezáčová H, Merhautová V (2005): Hyphal growth and mycorrhiza formation by the arbuscular mycorrhizal fungus Glomus claroideum BEG 23 is stimulated by humic substances. Mycorrhiza 15, 483-488
25. Hehmann A, Krienitz L, Koschel R (2001): Long-term phytoplankton changes in an artificially divided, top-down manipulated humic lake. Hydrobiologia 448, 83-96
26. Helbig B, Klöcking R, Wutzler P (1997): Anti-herpes simplex virus type 1 activity of humic acid-like polymers and their o-diphenolic starting compounds. Antivir Chem Chemother 8, 265-273
27. Helbig B, Klöcking R, Wutzler P (2003): Comparison of polymerisates derived from o-and p-diphenolic compounds with regard to their anti-HSV-1 activity in vitro and their chemical properties. Akad gemeinn Wiss Erfurt, Sitzungsber Mathem-Naturw Klasse 12, 153-163 (in German with English summary)
28. Höss S, Bergtold M, Haitzer M, Traunspurger W, Steinberg CEW (2001): Refractory dissolved organic matter can influence the reproduction of Caenorhabditis elegans (Nematoda). Freshwater Biol 46, 1-10
29. Höss S, Jüttner I, Traunspurger W, Pfister G, Schramm KW, Steinberg CEW (2002): Enhanced growth and reproduction of Caenorhabditis elegans (Nematoda) in the presence of 4-nonylphenol. Environ Poll 120, 169-172
30. Hseu YC, Huang HW, Wang SY, Chen HY, Lu FJ, Gau RJ, Yang HL (2002): Humic acid induces apoptosis in human endothelian cells. Toxicol Appl Pharm 182, 34-43
31. Huang TS, Lu FJ, Chopra IJ (1993): Inhibition of hepatic thyroxine 5′-monodeiodinase by humic acids. Environ Toxicol Chem 12, 1267-1271
32. Huang TS, Lu FJ, Tsai CW, Chopra IJ (1994): Effect of humic acids on thyroidal function. J Endocr Invest 17, 787-791
33. Hubbard PC, Barata EN, Canario AVM (2002): Possible disruption of pheromonal communication by humic acid in the goldfish, Carassius auratus. Aquat Toxicol 60, 169-183
34. Jackson TA, Hecky RE (1980): Depression of primary productivity by humic matter in lake and reservoir water of the boreal forest zone. Can J Fish Aquat Sci 37, 2300-2317
35. Janošek J, Bittner M, Hilscherová K, Bláha L, Giesy JP, Holoubek I (2007): AhR-mediated and antiestrogenic activity of humic substances. Chemosphere 67, 1096-1101
36. Jones RI (1998): Phytoplankton, primary production and nutrient cycling. In: Hessen DO, Tranvik LJ (eds), Aquatic Humic Substances - Ecology and Biogeochemistry. Springer, Berlin, pp 145-175
37. Jones RI (2005): Limnology of humic waters: Special theme or universal framework? Verh Intern Verein Limnol 29, 51-60
38. Karasyova AT, Klose OE, Menzel R, Steinberg CEW (2007): Impact of dissolved humic materials on growth of two closely related coccal green algal species. Env Sci Poll Res 14, 88-93
39. Kjerfve B (ed) (1994): Coastal Lagoon Processes. Elsevier Oceanography Series 60, Elsevier, Amsterdam
40. Kozlowsky-Suzuki B, Bozelli RL (2004): Resilience of a zooplankton community subjected to marine intrusion in a tropical coastal lagoon. Hydrobiologia 522, 165-177
41. th IHSS Meeting, Karlsruhe, Germany, pp 425-428
42. th IHSS Meeting, Karlsruhe, Germany, pp 437-440
43. Laurberg P, Andersen S, Pedersen IB, Ovesen L, Knudsen N (2003): Humic substances in drinking water and the epidemiology of thyroid disease. Biofactors 19, 145-153
44. Le Bourg É (2003): Delaying aging: Could the study of hormesis be more helpful than that of the genetic pathway used to survive starvation? Biogerontology 4, 319-324
45. Lee Y, Huang TS, Yang ML, Huang LR, Chen CH Lu FJ (1999): Peroxisome proliferation, adipocyte determination and differentiation of C3H10T1/2 fibroblast cells induced by humic acid: Induction of PPAR in diverse cells. J Cell Physiol 179, 218-225
46. Leenheer JA, Rostad CE (2004): Tannins and terpenoids as major precursors of Suwannee River fulvic acids. U.S. Geological Survey Scientific Investigations Report, 1004-5276, 16 pp
47. Lovley DR, Coates JD, Blunt-Harris EL, Phillips EJP, Woodward JC (1996): Humic substances as electron acceptors for microbial respiration. Nature 382, 445-448
48. Lutz I, Zhang J, Opitz R, Kloas W, Xu Y, Menzel R, Steinberg CEW (2005): Environmental signals: Synthetic humic substances act as xeno-estrogen and affect the thyroid system of Xenopus laevis. Chemosphere 61, 1183-1188
49. Mahr N, Klöcking HP, Klöcking R (2003): The effect of naturally occurring humic acids on the clotting factors IIa, VIIa and Xa. Akad gemeinn Wiss Erfurt, Sitzungsber Mathem-Naturw Klasse 12, 165-172 (in German, with English summary)
50. Matsuo AYO, Woodin BR, Reddy CM, Val AL, Stegeman JJ (2006): Humic substances and crude oil induce CYP1A expression in the Amazonian fish species Colossoma macropomum (tambaqui). Environ Sci Technol 40, 2851-2858
51. Meerbach A, Helbig B, Wutzler P (2003): In-vitro activity of polyhydroxycarboxylates against herpes viruses and HIV. Akad gemeinn Wiss Erfurt, Sitzungsber Mathem-Naturw Klasse 12, 139-151 (in German with English summary)
52. Meinelt T, Schreckenbach K, Knopf K, Wienke A, Stüber A, Steinberg CEW (2004): Humic substances increase the constitution of swordtail (Xiphophorus helleri). Aquat Sci 66, 239-245
53. Menzel R, Stürzenbaum S, Kulas J, Bärenwaldt A, Steinberg CEW (2005): Humic material induces behavioral and global transcriptional responses in the nematode Caenorhabditis elegans. Environ Sci Technol 39, 8324-8332
54. Meshcheryakova OV, Gruzdev AI, Nemova NN (2004): Comparative evaluation of carbohydrate metabolism in perch (Perca fluviatilis L) from water bodies with different contents of humic acids. Biol Bull 31, 15-20
55. Mesquita RMRS, Canário AVM, Melo E (2003): Partition of fish pheromones between water and aggregates of humic acids. Consequences for sexual signaling. Environ Sci Technol 37, 742-746
56. Minois N (2002): Longevity and aging: Beneficial effects of exposure to mild stress. Biogerontology 1, 15-29
57. Morrow G, Battistini S, Zhang P, Tanguay RM (2004): Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila. J Biol Chem 279, 43382-43385
58. Münster U (1985): Investigation about structure, distribution and dynamics of different organic substrates in the DOM of lake Plusssee. Arch Hydrobiol/Suppl 70, 429-480
59. Murphy CT, McCarrol SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C (2003): Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-284
60. Nykänen M, Kairesalo T, Mäkelä S, Huitu E, Ala-Opas P, Mannio J (2005): A typology and ecological classification system for Finnish lakes: applicability of the ECOFRAME scheme. Boreal Environ Res 10, 159-179
61. Pan B, Ning P, Xing BS (2008a): Humic Substances. Part 4: Sorption of hydrophobic organic contaminants. Env Sci Pollut Res (in press)
62. Pan B, Ning P, Xing BS (2008b): Humic Substances. Part 5: Sorption of pharmaceuticals and personal care products. Env Sci Pollut Res (in press)
63. th IHSS Meeting, Karlsruhe, Germany, pp 921-924
64. Paul A, Pflugmacher S, Steinberg CEW (2003): Correlation of spin concentration in humic substances with inhibitory effects on photosynthesis of aquatic macrophytes. Akad gemeinn Wiss Erfurt, Sitzungsber Mathem-Naturw Klasse 12, 205-217 (in German with English summary)
65. Pflugmacher S, Pietsch C, Rieger W, Steinberg CEW (2006): Influence of structural moieties of dissolved organic matter on the photosynthetic oxygen production of aquatic plants. Sci Total Environ 357, 169-175
66. Prokhotskaya LYu, Steinberg CEW (2007): Differential sensitivity of a coccal green alga and a cyanobacterial species to dissolved natural organic matter. Env Sci Pollut Res 14, Spec Issue, 11-18
67. Rask M, Viljanen M, Sarvala J (1999): Humic lakes as fish habitats. In: Keskitalo J, Eloranta P (eds), Limnology of Humic Waters. Backhuys, Leiden, pp 209-224
68. Ridge I, Walters J, Street M (1999): Algal growth control by terrestrial leaf litter: a realistic tool? Hydrobiologia 395/396, 173-180
69. Sarvala J, Ilmavirta V, Paasivirta L, Salonen K (1981): The ecosystem of the oligotrophic Lake Pääjärvi 3. Secondary production and an ecological energy budget of the lake. Verh Intern Verein Limnol 21, 422-427
70. Smital T, Luckenbach T, Sauerborn R, Hamdoun AM, Vega RL, Epel D (2004): Emerging contaminants - Pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mutat Res - Fundam Mol Mech Mutagen 552, 101-117
71. Steinberg CEW (2003): Ecology of Humic Substances in Freshwaters. Springer, Berlin
72. Steinberg CEW, Kamara S, Prokhotskaya VYu, Manusadžianas L, Karasyova TA, Timofeyev MA, Zhang J, Paul A, Meinelt T, Farjalla VF, Matsuo AYO, Burnison BK, Menzel R (2006): Dissolved humic substances - Ecological driving forces from the individual to the ecosystem level? Freshwater Biol 51, 1189-1210
73. Steinberg CEW, Manusadžianas L, Grigutytǧ R, Karitonas R, Jurkoniene S, Pflugmacher S (2004): Membrane depolarization and elevation of ROS-defensive mechanisms due to the impact of dissolved natural organic matter (NOM) in the Charophyte Nitellopsis obtusa. In: Martin-Neto L et al. (eds), Humic Substances and Soil and Water Environment. Embrapa, São Carlos, Brazil, pp 135-137
74. Steinberg CEW, Saul N, Pietsch K, Meinelt T, Rienau S, Menzel R (2007): Humic substances facilitate life in extreme aquatic environments and have the potential to extend lifespan of Caenorhabditis elegans. Ann Environ Sci 1, 81-90
75. Steinberg CEW, Paul A, Pflugmacher S, Meinelt T, Klöcking R, Wiegand C (2003): Pure humic substances have the potential to act as xenobiotic chemicals - A review. Fresenius Environ Bull 12, 391-401
76. Suhett, AL, MacCord F, Amado AM, Farjalla VF, Esteves FA (2004): Photodegradation of dissolved organic carbon in humic coastal lagoons (RJ, Brazil). In: Martin-Neto L et al. (eds), Humic Substances and Soil and Water Environment. Embrapa, São Carlos, Brazil, 61-63
77. Thomas H (2002): Ageing in plants. Mech Age Devel 123, 747-753
78. Thurman EM (1985): Organic Geochemistry of Natural Waters. Dr. W. Junk Publishers, Dordrecht
79. Timofeyev MA, Shatilina ZM, Bedulina DS, Menzel R, Steinberg CEW (2007): Natural organic (NOM) has the potential to modify the multixenobiotic resistance (MXR) activity in freshwater amphipods Eulimnogammarus cyaneus (Dyb) and Eulimnogammarus verrucosus (Gerst.). Comp Biochem Physiol B 146, 496-503
80. Timofeyev MA, Shatilina ZM, Kolesnichenko AV, Bedulina DS, Kolesnichenko VV, Pflugmacher S, Steinberg CEW (2006a): Natural organic matter (NOM) induces oxidative stress in freshwater amphipods Gammarus lacustris Sars and G. tigrinus (Sexton). Sci Total Environ 366, 673-681
81. Timofeyev MA, Shatilina ZM, Kolesnichenko AV, Kolesnichenko VV, Steinberg CEW (2006b): Specific antioxidant reactions to oxidative stress promoted by natural organic matter (NOM) in two amphipod species from Lake Baikal. Environ Toxicol 21, 104-110
82. Timofeyev MA, Steinberg CEW (2006): Comparative study of the antioxidant response to Natural Organic Matter (NOM) exposure in three Baikalean amphipod species from contrasting habitats. Comp Biochem Physiol B 145, 197-203
83. Timofeyev MA, Wiegand C, Burnison BK, Shatilina ZM, Pflugmacher S, Steinberg CEW (2004): Direct impact of natural organic matter (NOM) on freshwater amphipods. Sci Total Environ 319, 115-121
84. Tranvik LJ, Höfle MG (1987): Bacterial growth in mixed cultures on dissolved organic carbon from humic and clear waters. Appl Environ Microbiol 53, 482-488
85. Visser SA (1985): Physiological action of humic substances on microbial cells. Soil Biol Biochem 17, 457-462
86. Vuori KM, Muotka T (1999): Benthic communities in humic streams. In: Keskitalo J, Eloranta P (eds), Limnology of Humic Waters. Backhuys, Leiden, pp 193-207
87. Wang WH, Bray CM, Jones MN (1999): The fate of 14C-labelled humic substances in rice cells in cultures. J Plant Physiol 154, 203-211
88. Welch IM, Barrett PRF, Gibson MT, Ridge I (1990): Barley straw as an inhibitor of algal growth I: Studies in the Chesterfield Canal. J Appl Phycol 2, 231-239
89. rdP ed. Academic Press, San Diego, CA
90. Wiegand C, Meems N, Timofeyev M, Steinberg CEW, Pflugmacher S (2004): More evidence for humic substances acting as biogeochemicals on organisms. In: Ghabbour EA, Davies G (eds), Humic Substances: Nature's Most Versatile Materials. Taylor and Francis, New York, pp 349-363
91. Willén E (2003): Dominance patterns of phytoplankton algae in Swedish forest lakes. Hydrobiologia 502, 315-324
92. Yang HL, Hseu YC, Hseu YT, Lu FJ, Lin E, Lai JS (2004): Humic acid induces apoptosis in human premyelocytic leukemia HL-60 cells. Life Sci 75, 1817-1831
93. Zenkevics H, Klavins M, Vose V, Bucena A (2005): Humic acid reduce gonadotropin activity and hormonal sensitivity of frog oocytes. Aquat Toxicol 75, 380-383
94. Ziechmann W (1996): Huminstoffe und ihre Wirkungen. Spektrum Akademischer Verlag, Heidelberg